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| 1 | Linking atmospheric pollution to cryospheric change in the Third Pole region: current progress and future prospects显示文摘The Tibetan Plateau and its surroundings are known as the Third Pole(TP). This region is noted for its high rates of glacier melt and the associated hydrological shifts that affect water supplies in Asia. Atmospheric pollutants contribute to climatic and cryospheric changes through their effects on solar radiation and the albedos of snow and ice surfaces; moreover, the behavior and fates within the cryosphere and environmental impacts of environmental pollutants are topics of increasing concern. In this review, we introduce a coordinated monitoring and research framework and network to link atmospheric pollution and cryospheric changes(APCC) within the TP region. We then provide an up-to-date summary of progress and achievements related to the APCC research framework, including aspects of atmospheric pollution’s composition and concentration, spatial and temporal variations, trans-boundary transport pathways and mechanisms, and effects on the warming of atmosphere and changing in Indian monsoon, as well as melting of glacier and snow cover. We highlight that exogenous air pollutants can enter into the TP’s environments and cause great impacts on regional climatic and environmental changes. At last, we propose future research priorities and map out an extended program at the global scale. The ongoing monitoring activities and research facilitate comprehensive studies of atmosphere–cryosphere interactions, represent one of China’s key research expeditions to the TP and the polar regions and contribute to the global perspective of earth system science. | Shichang Kang Qianggong Zhang Yun Qian Zhenming Ji Chaoliu Li Zhiyuan Cong Yulan Zhang Junming Guo Wentao Du Jie Huang Qinglong You Arnico K.Panday Maheswar Rupakheti Deliang Chen Orjan Gustafsson Mark H.Thiemens Dahe Qin | 2019 | National Science Review2019，6，4： | 35 |
| 2 | Global Attractors for a Nonclassical Diffusion Equation显示文摘我们在 H_0~1 证明全球引起注意的人的存在(为一个非古典的散开方程的Ω) 。非线性 f 的二种类型被考虑:一个人是批评代表,并且其它是任意的顺序的多项式生长。 | Chun You SUN Su Yun WANG Cheng Kui ZHONG | 2007 | Acta Mathematica Sinica,English Series2007，23，7： | 20 |
| 3 | Reliability of transthoracic echocardiography in estimating the size of Amplatzer septal occluder and guiding percutaneous closure of atrial septal defects显示文摘在中国的背景, transthoracic echocardiography ( TTE )流行地为 atrial 为干预前检查被使用氏族的缺点( ASD )并且为指导 ASD closure.However ,为指导 ASD 闭合决定 TTE 的 ASD 尺寸和安全和功效的能力仍然广泛地没被接受试图评估 TTE 的功效和安全的这研究以前使用了,在期间并且在有 Amplatzer 氏族的 occluders ( ASO )的 transcatheter ASD 闭合以后 .Methods 68 个题目( 15 个男人和 53 个女人;吝啬的年龄( | LI Gui-shuang KONG Guang-ming JI Qiu-shang LI Ji-fu CHEN Yu-guo YOU Bei-an ZHANG Yun | 2008 | Chinese Medical Journal2008，，11： | 10 |
| 4 | Express=on of Brain-derived Neurotrophic Factor and Tyrosine Kinase B in Cerebellum of Poststroke Depression Rat Model显示文摘 | Yun Li Chun Peng Xu Guo Jun-Jie You Harishankar Prasad Yadav | 2015 | Chinese Medical Journal2015，，21： | 9 |
| 5 | Response surface modeling-based source contribution analysis and VOC emission control policy assessment in a typical ozone-polluted urban Shunde,China显示文摘To develop a sound ozone(O_3) pollution control strategy,it is important to well understand and characterize the source contribution due to the complex chemical and physical formation processes of O_3.Using the 'Shunde' city as a pilot summer case study,we apply an innovative response surface modeling(RSM) methodology based on the Community Multi-Scale Air Quality(CMAQ) modeling simulations to identify the O_3 regime and provide dynamic analysis of the precursor contributions to effectively assess the O_3 impacts of volatile organic compound(VOC) control strategy.Our results show that Shunde is a typical VOC-limited urban O_3 polluted city.The 'Jiangmen' city,as the main upper wind area during July 2014,its VOCs and nitrogen oxides(NO_x) emissions make up the largest contribution(9.06%).On the contrary,the contribution from local(Shunde) emission is lowest(6.35%) among the seven neighbor regions.The local VOCs industrial source emission has the largest contribution comparing to other precursor emission sectors in Shunde.The results of dynamic source contribution analysis further show that the local NO_x control could slightly increase the ground O_3 under low(10.00%) and medium(40.00%)reduction ratios,while it could start to turn positive to decrease ground O_3 under the high NO_x abatement ratio(75.00%).The real-time assessment of O_3 impacts from VOCs control strategies in Pearl River Delta(PRD) shows that the joint regional VOCs emission control policy will effectively reduce the ground O_3 concentration in Shunde. | Zhiqiang You Yun Zhu Carey Jang Shuxiao Wang Jian Gao Che-Jen Lin Minhui Li Zhenghua Zhu Hao Wei Wenwei Yang | 2017 | Journal of Environmental Sciences2017，29，1： | 7 |
| 6 | Evolutionary analysis of allotetraploid hybrids of red crucian carp×common carp,based on ISSR,AFLP molecular markers and cloning of cyclins genes显示文摘The allotetraploid hybrids of red crucian carp × common carp are the first reported artificially cultured polyploid fish with bisexual fertility and stable inheritance in vertebrate. Using ISSR and AFLP markers and the cyclins genes, the genomes and cyclin gene sequence changes were analyzed between the allotetraploid hybrids and their parents. The results indicated that the allotetraploids inherited many genetic characteristics from their parents and the genetic characteristics were stable after 15 generations. However, the allotetraploids had a closer genetic relationship with their original female parents and represented a bias toward the maternal progenitor. DNA fingerprinting analysis showed that the allotetraploids had undergone sequences deletion from their original parents and that the deleted sequences were mostly from the male parent's genome. Some non-parental bands were found in the allotetraploid hybrids. Sequences analysis of the cyclin A1 and B1 genes showed nonsynonymous substitutions of single nucleotides in codons that were different from their original parents, leading to non-parental amino acid loci. We speculate that the non-additivity in the allotetraploids, compared with their progenitors, could be an adjustment to the genomic shock from heterozygosity and polyploidy, allowing maintenance of genetic stability. | LIU LiangGuo YAN JinPeng LIU ShaoJun LIU Dong YOU CuiPing ZHONG Huan TAO Min LIU Yun | 2009 | Chinese Science Bulletin2009，54，16： | 6 |
| 7 | Demographic Characteristics and Environmental Risk Factors Exposure of Birth Defects in Pregnant Women: A Population-based Study显示文摘Worldwide, the incidence of birth defects in low-income countries is 6.42%, while in middle-income and high-income countries it is 5.57% and 4.72%, respectively;approximately 303, 000 newborns die from birth defects each year. In China, the incidence of birth defects is about 5.6%, and around 8.14 million people have congenital disabilities, accounting for 9.6% of total disabled people[1]. Birth defect remains a major clinical and public health challenge because of its high fatality rate and protracted and severe sequela. | LIN Hong LUO Mi Yang LUO Jia You ZENG Rong LI Ya Mei DU Qi Yun FANG Jun Qun | 2019 | Biomedical and Environmental Sciences2019，32，1： | 5 |
| 8 | Learning Experience: An Alternative Understanding Inspired by Thinking Through Confucius显示文摘Purpose:This article aims to provide an alternative understanding of learning experience in contrast to the dominant constructivist interpretation,and discuss its implication for pedagogy.Design/Approach/Methods:The aim is specifically achieved in the comparison between a review of how experience is understood in constructivism and its philosophical underpinnings and an exploration of how it can be understood alternatively inspired by Confucius’educational thought and premised on his ontology.Drawing on this philosophical discussion,learning experience is reinterpreted.Findings:Beyond rationally translating experience into knowledge or gaining knowledge on the basis of experience,learning leads students to immediately and consistently experience dao in which tian and ren harmoniously unit.This experience renders aesthetics and religiousness in learning and moral transformation in life events.Originality/Value:By illustrating this ontological alternative of learning experience,this article is an attempt to fundamentally decolonize thinking about pedagogy. | Yun You | 2020 | ECNU Review of Education2020，3，1： | 5 |
| 9 | Seroprevalence of Neutralizing Antibodies against Six Human Adenovirus Types Indicates the Low Level of Herd Immunity in Young Children from Guangzhou, China显示文摘Human adenoviruses(HAdVs) commonly cause many diseases such as respiratory diseases, gastroenteritis, cystitis worldwide. HAdV-3,-7,-4 and emergent HAdV-55 and HAdV-14 are the most important types causing severe respiratory diseases. There is no effective drug available for clinical treatment, and no vaccine available for the general population.Therefore, it is important to investigate the seroprevalence against HAdV for developing novel vaccines and vectors. In this study, we investigated the seroprevalence and titer levels of neutralizing antibodies(NAb) against HAdV-3,-4,-7,-14,-55,and-11 in total 278 healthy populations between 0 months and 49 years of age(228 children and 50 adults) from Guangzhou. In children under the age of 18 years, the seropositive rates were significantly increased against HAdV-3 at12.07%, 33.96%, and 64.29% and against HAdV-7 at 0%, 18.87%, and 19.05% in age groups of 1–2, 3–5, and 6–17 years,respectively. The seroprevalence was very low(0% - 8.1%) for all other four types. In adults aged between 18 and49 years, HAdV-3,-4, and-7(> 50.00%) were the most common types, followed by HAdV-14(38.00%),-55(34.00%),and-11(24.00%). Adults tended to have high NAb titers against HAdV-4 and-55. HAdV-55-seropositive donors tended to be HAdV-11-and HAdV-14-seropositive. These results indicated the low level of herd immunity against all six HAdV types in young children, and HAdV-14,-55,-11 in adults from Guangzhou City. Our findings demonstrate the importance of monitoring HAdV types and developing vaccines against HAdV for children and adults. | Xingui Tian Ye Fan Changbing Wang Zhenwei Liu Wenkuan Liu Yun Xu Chuncong Mo Aiping You Xiao Li Xia Rong Rong Zhou | 2021 | Virologica Sinica2021，36，3： | 5 |
| 10 | Remimazolam besylate for sedation of postoperative patients in intensive care units: a phase I, open label, dose-finding study显示文摘To the Editor:Remimazolam besylate is a novel,ultrashort-acting benzodiazepine with a rapid and a predictable onset and offset profile,no accumulation and extended effect,and independence of organ elimination. | Yun Tang Xiaobo Yang Huaqing Shu Yuan Yu Jiqian Xu Shangwen Pan Xiaojing Zou Shiying Yuan You Shang | 2022 | Chinese Medical Journal2022，135，17： | 5 |
| 11 | Computed tomography and magnetic resonance imaging findings of metastatic rectal linitis plastica from prostate cancer:A case report and review of literature显示文摘Linitis plastica is a rare condition showing circumferentially infiltrating intramural anaplastic carcinoma in a hollow viscus, resulting in a tissue thickening of the involved organ as constricted, inelastic, and rigid. While most secondary rectal linitis plastica(RLP) is caused by metastasis from stomach, breast, gallbladder, or bladder cancer, we report an extremely rare and unique case of secondary RLP due to prostate cancer with computed tomography(CT) and magnetic resonance imaging(MRI) findings, including diffusion weighted imaging(DWI). A 78-year-old man presented with approximately a 2-mo history of constipation and without cancer history. On sigmoidoscopy, there was a luminal narrowing and thickening of rectum with mucosa being grossly normal in its appearance. On contrast-enhanced CT,marked contrast enhancement with wall thickening of rectum was noted. On pelvic MRI, rectal wall thickening showed a target sign on both T2-weighted imaging and DWI. A diffuse infiltrative lesion was suspected in the prostate gland based on low signal intensity on T2-weighted imaging and restricted diffusion. A transanal full-thickness excisional biopsy revealed metastasis from a prostate adenocarcinoma invading the submucosa to the muscularis propria consistent with metastatic RLP. We would like to emphasize the CT and MRI findings of metastatic RLP due to prostate cancer. | Jin Hee You Ji Soo Song Kyu Yun Jang Min Ro Lee | 2018 | World Journal of Clinical Cases2018，6，12： | 5 |
| 12 | Fructus phyllanthi tannin fraction induces apoptosis and inhibits migration and invasion of human lung squamous carcinoma cells in vitro via MAPK/MMP pathways显示文摘目的: 从传统的西藏的药 Fructus phyllanthi 的 Fructus phyllanthi 丹宁部分(PTF ) 被发现了在老鼠禁止肺和肝癌。在这研究,我们在人的肺调查了 PTF 的 anticancer 机制在 vitro 的有鳞的癌房间。 | Hai-juan ZHAO Ting LIU Xin MAO Shu-xian HAN Ri-xin LIANG Lian-qiang HUI Chun-yu CAO Yun YOU Lan-zhen ZHANG | 2015 | Acta Pharmacologica Sinica2015，36，6： | 4 |
| 13 | A simple and efficient synthesis of 2-substituted benzothiazoles catalyzed by H_2O_2/HCl显示文摘A simple and efficient procedure for the synthesis of substituted benzothiazoles through condensation of 2-aminothiophenol with aromatic aldehydes in the presence of H_2O_2/HCl system in ethanol at room temperature is described.The target compounds have been characterized by ~1H NMR,^(13)C NMR,IR and MS.Short reaction time,easy and quick isolation of the products,and excellent yields are the main advantages of this procedure. | Hong Yun Guo Ji Chao Li You Le Shang | 2009 | Chinese Chemical Letters2009，20，12： | 4 |
| 14 | Characteristics of the Spectra of Superior Vena Cava Flow Doppler Velocities in Primary Pulmonary Hypertension with Tricuspid Regurgitation显示文摘 | CHEN Hong-mao DUAN Yun -you LI Juan ZHOU Ning LIU Shan-shan | 2007 | Journal of US-China Medical Science2007，4，1： | 3 |
| 15 | Sensitivity Analysis of the Effect of Speed and Inclination Angle on Water-Entry Slamming Pressure of the Bow显示文摘In this paper,a method about the water-entry slamming of a two-dimensional(2D)bow structure has been proposed based on the experimental and simulation results.According to this method,the sensitivity analysis has been carried out about the effect of speed and inclination angle on the slamming pressure of the bow.Firstly,a 2D ship bow experimental model was performed to obtain the slamming pressure distribution at different measuring points under different speeds.Then,numerical simulation for the water-entry slamming of this experimental model was conducted to obtain the pressure distribution on the experimental model under different working conditions.Finally,the experimental results were compared with the numerical simulation results to evaluate the effect of speed and inclination angle on the slamming pressure of the bow.The results show that the slamming pressure is more sensitive to speed variation within the low-speed range.The effect of inclination angle on the slamming pressure is more obvious in the small angle condition.When the inclination angle is larger than 45°,the effect is limited. | ZHANG Jian YOU Yun YAO Zhi HUO Fa-li | 2020 | China Ocean Engineering2020，34，3： | 3 |
| 16 | Recent Progress in Metal-Organic Frameworks@Cellulose Hybrids and Their Applications显示文摘In recent years,metal-organic frameworks(MOFs)are attracting increasing attention due to their charming properties.However,the intrinsic fragility,powdered crystalline state,and poor processibility of MOFs hinder their further application.By this,the designs of MOF-based aerogels,hydrogels,membranes are effective ways to solve this problem.Graphene,silica,synthetic polymer and cellulose are the commonly used raw materials for fabricating MOF-based aerogels,hydrogels,and membranes.Among them,cellulose and its derivatives are the best candidates to support the powdered MOFs from the perspectives of economy,environmental protection and property.This review focuses on discussing the advantages of MOF@cellulose hybrids in applications such as water treatment,antibacterial,gas separation and adsorption,energy storage,drug delivery,catalysis,and other smart composites.MOF@cellulose-based aerogels,hydrogels and membranes can provide valuable guidance for investigating the practical application of MOFs in terms of processability,reusability,stability and easiness in handling. | Xiongli Liu Yun Xiao Zhiyuan Zhang Zifeng You Jinli Li Dingxuan Ma Baiyan Li | 2021 | Chinese Journal of Chemistry2021，39，12： | 2 |
| 17 | Incidence,Prevalence,and Mortality of Four Major Chronic Non-communicable Diseases—China,1990-2017显示文摘Introduction Chronic and non-communicable diseases(NCDs)have become an important public health concern in China.We aimed to estimate the incidence,prevalence,and mortality of four major NCDs including cardiovascular disease(CVD),cancer,chronic respiratory diseases(CRD),and diabetes in China during 1990-2017.Methods The general analytic framework of Global Burden of Diseases Study 2017(GBD 2017)was applied.Data from Disease Surveillance Point System,censuses,and Chinese Center for Disease Control and Prevention Cause-of-Death Reporting System were used for mortality estimates.National surveys,cancer registries,and published studies were used for incidence and prevalence estimates.Results In 2017,new cases for CVD,cancer,and diabetes were 13.5,4.6,and 3.3 million,an increase of 120.4%,159.7%,and 57.3%respectively compared with 1990.There were 9.6 million incident cases for CRD in 2017,a 4.9%decrease compared with 1990.A total of 8.1 million people died from cancer,CVD,CRD,and diabetes in China in 2017.There was a substantial decline in age-standardized mortality rate for CRD and a steady but slow decline for CVD and cancer.During 1990-2017,the age-standardized prevalence rate increased by 7.4%,135.2%,and 17.0%for CVD,cancer,and diabetes respectively.Conclusions and Implications for Public Health Practice The accumulated prevalence of the four major NCDs are increasing but the age-standardized mortality rate for CVD,cancer,and CRD has been on a decline during 1990-2017.More effective intervention strategies should be developed to deal with the continuously increasing burden caused by NCDs in China. | Peng Yin Jinlei Qi Yunning Liu Jiangmei Liu Jinling You Lijun Wang Maigeng Zhou | 2019 | China CDC weekly2019，1，3： | 2 |
| 18 | Carriers of Inactive Hepatitis B Virus Are Still at Risk for Hepatocellular Carcinoma and Liver-Related Death显示文摘 | Jin–De Chen Hwai–I. Yang Uchenna H. Iloeje San–Lin You Sheng–Nan Lu Li–Yu Wang Jun Su Chien–An Sun Yun–Fan Liaw Chien–Jen Chen | 2010 | Gastroenterology2010，，5： | 2 |
| 19 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int J Cancer2012，，9： | 2 |
| 20 | Characteristics of the quasi-16-day wave in the mesosphere and lower thermosphere region as revealed by meteor radar,Aura satellite,and MERRA2 reanalysis data from 2008 to 2017显示文摘This study presents an analysis of the quasi-16-day wave(Q16DW)at three stations in the middle latitudes by using a meteor radar chain in conjunction with Aura Microwave Limb Sounder temperature data and MERRA2(Modern-Era Retrospective Analysis for Research and Applications,Version 2)reanalysis data from 2008 to 2017.The radar chain consists of three meteor radar stations located at Mohe(MH,53.5°N,122.3°E),Beijing(BJ,40.3°N,116.2°E),and Wuhan(WH,30.5°N,114.6°E).The Q16DW wave exhibits similar seasonal variation in the neutral wind and temperature,and the Q16DW amplitude is generally strong during winter and weak around summer.The Q16DW at BJ was found to have secondary enhancement around September in the zonal wind,which is rarely reported at similar latitudes.The latitudinal variations of the Q16DW in the neutral wind and temperature are quite different.The Q16DW at BJ is the most prominent in both neutral wind components among the three stations and the Q16DW amplitudes at MH and WH are comparable,whereas the wave amplitude in temperature decreases with decreasing latitude.The quasi-geostrophic refractive index squared at the three stations in the period from 2008 to 2017 was revealed.The results indicate that the Q16DW in the mesosphere and lower thermosphere(MLT)at MH has a limited contribution from the lower atmosphere.Around March and October,the Q16DW in the troposphere at BJ can propagate upward into the MLT region,whereas at WH,the contribution to the Q16DW in the MLT region is largely from the mesosphere. | Yun Gong Zheng Ma Chun Li XieDong Lv ShaoDong Zhang QiHou Zhou ChunMing Huang KaiMing Huang You Yu GuoZhu Li | 2020 | Earth and Planetary Physics2020，4，3： | 2 |
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