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| 1 | Simultaneous removal of COD and nitrogen using a novel carbon-membrane aerated biofilm reactor显示文摘膜给简历电影反应堆充气了是为废水处理的一种有希望的技术。在这研究,碳膜给简历电影反应堆(CMABR ) 充气了被开发了,到同时把碳 organics 和氮从一个反应堆移开。当它与 20 h 的一水力的保留时间(HRT ) 被操作,结果证明 CMABR 有一个高化学的氧要求(货到付款) 和氮移动效率,并且它也显示出完美的表演,就算 HRT 被弄短到 12 h。在这个时期,货到付款,氨氮(NH4+-N ) ,和总氮(TN ) 的移动效率分别地到达了 86% , 94% ,和 84% 。然而,当 HRT 被弄短到 8 h, NH4+-N 和 TN 的移动效率很快衰退了。这因为非编织的纤维和很高器官的装载率上的生物资源的过多的生长。荧光原位杂交(鱼) 分析显示氧化的氨细菌(AOB ) 主要在简历电影的内部层被散布。在一部简历电影的 AOB 和 eubacteria 的共存能提高货到付款和氮的同时的移动。 | HU Shaowei YANG Fenglin SUN Cui ZHANG Jianye WANG Tonghua | 2008 | Journal of Environmental Sciences2008，20，2： | 12 |
| 2 | DNA barcoding provides distinction between Radix Astragali and its adulterants显示文摘Based on variable nuclear and/or organellar DNA sequences among vastly divergent species as well as morphologically indistinguishable species, DNA barcoding is widely applicable in species identification, biodiversity studies, forensic analyses, and authentication of medicinal plants. The roots of Astragalus membranaceus and A. membranaceus var. mongholica are commonly used as Radix Astragali in several Asian countries, including China, Japan, and Korea. However, in addition to the two species recorded in the Chinese Pharmacopoeia, there are twenty-three species from different genera including Astragalus, Oxytropis, Hedysarum, and Glycyrrhiza, which have been used as adulterants not only in trading markets but also by the herbal medicine industry. Therefore, a simple, reliable, and accurate classification method is important for distinguishing authentic Radix Astragali from its adulterants. In this study, we acquired data for 37 samples from four related genera within the family Fabaceae. Then we compared four candidate DNA barcoding markers using ITS, matK, rbcL, and coxI sequences from nuclear, chloroplast, and mitochondrial genomes, all commonly used for plants to identify genetic variations among genera, intraspecies, and interspecies. We observed higher divergences among genera and interspecies for ITS, which have the average Kimura 2-parameter distances of 4.5% and 14.1%, respectively, whereas matK was found to have sufficient divergence at the intraspecific level. Moreover, two indels detected in the matK sequence are useful for PCR studies in distinguishing Radix Astragali from its adulterants. This study suggests that the combined barcoding regions of ITS and matK are superior barcodes for Radix Astragali and further studies should focus on evaluating the applicability and accuracy of such combined markers for a wide range of traditional Chinese herbs. | GUO HaiYan1,2, WANG WeiWei2, YANG Ning2, GUO BaoLin3, ZHANG Sun2, YANG RuiJing2, YUAN Ye2, YU JunLin4, HU SongNian2, SUN QiShi1 & YU Jun2 1School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China 2Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101300, China 3Chinese Academy of Medical Sciences, Peking Union Medical College Institute of Medicinal Plant Development, Beijing 100094, China 4Department of Chemistry, Tonghua Normal College, Tonghua 134002, China | 2010 | Science China(Life Sciences)2010，53，8： | 7 |
| 3 | Effect of Tangnaikang on TGF-β_1-induced transdifferentiation of human renal tubular epithelial HK-2 cells显示文摘OBJECTIVE: To explore the function of Tangnaikang (TNK) in the prevention and treatment of renal interstitial fibrosis through transdifferentiation of the human renal tubular epithelial cell line HK-2 induced by transforming growth factor-β1(TGF-β1).METHODS: HK-2 cells cultured in dulbecco's modified eagle medium/F12 (1∶1) with 10% fetal calf serum were divided into six groups: blank control group, TGF-β1 group (TGF-β1 10 ng/mL), serum control group (TGF-β1 10 ng/mL+10% serum), treatment group 1 (TGF-β1 10 ng/mL+ 5% TNK serum),treatment group 2 (TGF-β1 10 ng/mL+10% TNK serum), and treatment group 3 (TGF-β1 10 ng/mL+20% TNK serum). Cell proliferation was detected by 4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Expression of α-smooth muscle actin (α-SMA) and E-cadherin were observed by immunohistochemical assay. The contents of collagen Ⅰ (Col Ⅰ), collagen Ⅲ (Col Ⅲ), and fibronectin (FN) in the culture medium supernatant were detected by ELISA.RESULTS: E-cadherin was expressed and α-SMA was not expressed in normal HK-2 cells. In HK-2 cells cultured with TGF-β1,α-SMA expression significantly increased, HK-2 cells significantly proliferated, and secretion of Col Ⅰ, Col Ⅲ, and FN significantly increased compared with the blank control group (all P<0.05). In the HK-2 cells cultured with TGF-β1 and TNK serum, the expression of α-SMA significantly decreased, the expression of E-cadherin significantly increased, and the cell proliferation and the secretion of Col Ⅰ, Col Ⅲ and FN were significantly inhibited compared with the TGF-β1 group (all P<0.05).CONCLUSION: TNK can inhibit cell proliferation and reduce secretion of Col Ⅰ, Col Ⅲ, and FN.This indicates that TNK can inhibit transdifferentiation of human renal tubular epithelial cells induced by TGF-β1, with the effect of preventing and treating renal interstitial fibrosis. | Lixia Yang Xinhuan Ma Tao Cheng Tonghua Liu Lili Wu Wen Sun Margetts Peter Joseph | 2013 | Journal of Traditional Chinese Medicine2013，33，3： | 5 |
| 4 | De-colorization of Reactive Brilliant Orange X-GN by a novel rotating electrochemical disc process显示文摘A novel electrochemical setup for wastewater treatment-rotating electrochemical disc process(RECDP)was developed in this article. The anode and cathode are distributed alternatively and evenly on a flat round disc,which was designed to improve mass transfer of organics from bulk solution to electrode surface,while at the same time increasing oxygen transfer from air to the liquid to benefit the organics oxidization.The color removal of dye Reactive Brilliant Orange X-GN(RBO)was experimentally investigate... | Zhong Dengjie Yang Ji Xu Yunlan Jia Jinping Wang Yalin Sun Tonghua | 2008 | Journal of Environmental Sciences2008，20，8： | 3 |
| 5 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://links.lww.com7CM9/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 6 | The Surface Energy Budget and Its Impact on the Freeze-thaw Processes of Active Layer in Permafrost Regions of the Qinghai-Tibetan Plateau显示文摘The surface energy budget is closely related to freeze-thaw processes and is also a key issue for land surface process research in permafrost regions.In this study,in situ data collected from 2005 to 2015 at the Tanggula site were used to analyze surface energy regimes,the interaction between surface energy budget and freeze-thaw processes.The results confirmed that surface energy flux in the permafrost region of the Qinghai-Tibetan Plateau exhibited obvious seasonal variations.Annual average net radiation(R_(n))for 2010 was 86.5 W m^(-2),with the largest being in July and smallest in November.Surface soil heat flux(G_(0))was positive during warm seasons but negative in cold seasons with annual average value of 2.7 W m^(-2).Variations in R_(n) and G_(0) were closely related to freeze-thaw processes.Sensible heat flux(H)was the main energy budget component during cold seasons,whereas latent heat flux(LE)dominated surface energy distribution in warm seasons.Freeze-thaw processes,snow cover,precipitation,and surface conditions were important influence factors for surface energy flux.Albedo was strongly dependent on soil moisture content and ground surface state,increasing significantly when land surface was covered with deep snow,and exhibited negative correlation with surface soil moisture content.Energy variation was significantly related to active layer thaw depth.Soil heat balance coefficient K was>1 during the investigation time period,indicating the permafrost in the Tanggula area tended to degrade. | Junjie MA Ren LI Hongchao LIU Zhongwei HUANG Tonghua WU Guojie HU Yao XIAO Lin ZHAO Yizhen DU Shuhua YANG | 2022 | Advances in Atmospheric Sciences2022，39，1： | 1 |
| 7 | Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes,by activating NO-AMPK pathway 显示文摘 | Thandapilly Sijo J Louis Xavier L Yang Tonghua | 2011 | Eur J Pharmacol2011，668，12： | 1 |
| 8 | Carbon membrane-a- erated biofilm reactor for synthetic wastewater treatment 显示文摘 | Liu Huijun Yang Fenglin Wang Tonghua | 2007 | Bio- process and Biosystems Engineering2007，30，4： | 1 |
| 9 | Effects of Diet on the Volatile Flavor and Nutritional Ingredients of Common Octopus(Octopus vulgaris)显示文摘Cephalopods are important economic shellfish that have been developed extensively in the coastal water of various countries. Octopus vulgaris is a large-scaled economic cephalopod that is mainly cultured in South China. This study explored the effect of different diets on the volatile flavor and nutritional ingredients of O. vulgaris. Four diets were tested in four groups: Group A(fish(Scomberomorus niphonius)), Group B(crab(Helice tridens tientsinensis Rathbun)), Group C(clam(Mactra veneriformis)), and Group D(squid(Loligo japonica)). Octopus muscles were sampled after 36 days of feeding, and volatile flavor substances(VFSs), fatty acids(FAs), and amino acids(AAs) were detected. Results showed that the VFSs, FAs, and AAs of octopus in the four groups were obviously different. The sum of volatile ketones and aldehydes was higher in Group B than in the other groups, which could present much more flavors. All groups were abundant in unsaturated FAs, including eicosapentaenoic acid(EPA) and docosahexaenoic acid(DHA). In terms of content and variety, the FAs in Group B were more beneficial to human health than those in the other groups. The content of each AA in Group B was basically higher than those in the other groups and was significantly higher than that in Group D(P < 0.05). Comparing the VFSs, FAs, and AAs in samples fed with four kinds of diets, the results indicate that using crab to feed O. vulgaris can achieve better effects on volatile flavor and nutritional ingredients. | LUO Qihao WANG Weijun LI Zan ZHU Xinghua WANG Xue ZHANG Tonghua XU He YANG Jianmin | 2021 | Journal of Ocean University of China2021，20，2： | 1 |
| 10 | Carbon membrane- aerated biofilm reactor for synthetic wastewater treatment显示文摘 | Liu Huijun Yang Fenglin Wang Tonghua | 2007 | Bioprocess and Biosystems Engineering2007，30，4： | 1 |
| 11 | Low-temperature H2S removal from gas streams with SBA-15 supported ZnO nanoparticles显示文摘 | Wang Xiaohui Sun Tonghua Ji Yang | 2008 | Chemical Engineering Journal2008，142，： | 1 |
| 12 | Low-temperature H 2 S removal from gas streams with SBA-15 supported ZnO nanoparticles显示文摘 | Wang Xiaohui Sun Tonghua Yang Ji | 2008 | Chem Eng J2008，142，： | 1 |
| 13 | Evaluation and spatio-temporal analysis of surface energy flux in permafrost regions over the Qinghai-Tibet Plateau and Arctic using CMIP6 models显示文摘The surface energy budget over the Qinghai-Tibet Plateau(QTP)and the Arctic significantly influences the climate system with global consequences.The performances of 30 selected Coupled Model Intercomparison Project Phase 6(CMIP6)models were evaluated based on six sites in the QTP and Arctic.The simulation results for latent heat flux(LE)were more accurate in the QTP,where the correlation coefficient and root mean square error(RMSE)were 0.9 and 30 W m−2,respectively.The results for sensible heat flux(H)were more accurate in the Arctic,the correlation coefficient and RMSE were 0.8 and 24 W m−2,respectively.Furthermore,the multiple models mean results revealed that the surface energy flux had seasonal variation and regional differences over the QTP and the Arctic.In the QTP,H was the lowest in winter,increased in spring,and reached the maximum in summer.However,the transitional changes in spring and autumn were not apparent in the Arctic,mainly due to seasonal net radiation difference between the two places.LE was affected by precipitation and surface soil moisture content.This work is important for understanding land-atmosphere interactions and useful for improving the accuracy of land surface models simulations. | Junjie Ma Ren Li Zhongwei Huang Tonghua Wu Xiaodong Wu Lin Zhao Hongchao Liu Guojie Hu Yao Xiao Yizhen Du Shuhua Yang Wenhao Liu Yongliang Jiao Shenning Wang | 2022 | International Journal of Digital Earth2022，15，1： | 0 |
| 14 | Thermal Inertia of 330 MW Circulating Fluidized Bed Boiler during Load Change显示文摘The operating principles of Circulating Fluidized Bed(CFB)boilers involve a significant amount of heat accumulation,which forms the thermal inertia of the boiler and hinders the improvement of its variable load response rate.This study aims to characterize the thermal inertia of CFB boilers by evaluating the change in the boiler's heat accumulation corresponding to the change in unit power generation.The thermal inertia of a 330MW CFB boiler was determined through the collection of operating data under four different operating conditions of 30%,50%,75%,and 100%load.The study proposes to substitute the existing refractory material with a metal grille to reduce the thermal inertia of the boiler.The effect of the metal grille on heat transfer was confirmed through verification on a 440 t/h CFB boiler,and its performance change and thermal inertia reduction were further predicted.The results indicate that over 50%of the total thermal inertia of CFB boilers originates from the refractory material.The use of metal grille in place of refractory material improved heat transfer in the furnace,resulting in a decrease of the furnace chamber temperature by 13℃in the 330 MW CFB boiler.This reduction of thermal inertia by 30%-35%will facilitate faster load lifting and lowering of the boiler,fulfilling the requirement for flexible peaking. | SUN Guorui WU Haowen LIU Shangzhong LIU Tonghua LIU Jixiang YANG Hairui ZHANG Man | 2023 | Journal of Thermal Science2023，32，5： | 0 |
| 15 | A gap-free reference genome reveals structural variations associated with flowering time in rapeseed(Brassica napus)显示文摘Allopolyploid oilseed rape(Brassica napus)is an important oil crop and vegetable.However,the latest version of its reference genome,with collapsed duplications,gaps,and other issues,prevents comprehensive genomic analysis.Herein,we report a gap-free assembly of the rapeseed cv.Xiang5A genome using a combination of ONT(Oxford Nanopore Technologies)ultra-long reads,PacBio high-fidelity reads,and Hi-C datasets.It includes gap-free assemblies of all 19 chromosomes and telomere-to-telomere assemblies of eight chromosomes.Compared with previously published genomes of B.napus,our gap-free genome,with a contig N50 length of 50.70 Mb,has complete assemblies of 9 of 19 chromosomes without manual intervention,and greatly improves contiguity and completeness,thereby representing the highest quality genome assembly to date.Our results revealed that B.napus Xiang5A underwent nearly complete triplication and allotetraploidy relative to Arabidopsis thaliana.Using the gap-free assembly,we found that 917 flowering-related genes were affected by structural variation,including BnaA03.VERNALIZATION INSENSITIVE 3 and BnaC04.HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1.These genes may play crucial roles in regulating flowering time and facilitating the adaptation of Xiang5A in the Yangtze River Basin of China.This reference genome provides a valuable genetic resource for rapeseed functional genomic studies and breeding. | Bao Li Qian Yang Lulu Yang Xing Zhou Lichao Deng Liang Qu Dengli Guo Rongkui Hui Yiming Guo Xinhong Liu Tonghua Wang Lianyi Fan Mei Li Mingli Yan | 2023 | Horticulture Research2023，10，10： | 0 |
| 16 | Acupuncture Combined with Massage for Treatment of 200 cases of Scapulohumeral Periarthritis显示文摘AcupunctureCombinedwithMassageforTreatmentof200casesofScapulohumeralPeriarthritis￥YangTonghua;HuChanghai;QiRuihong(CentralHos... | Yang Tonghua Hu Changhai Qi Ruihong(Central Hospital of Mudanjiang Administritive Bureau of Forest, Helongjiang Province) | 1995 | 中国针灸1995，15，S2： | 0 |
| 17 | Acupuncture Combined with Plucking Muscle Method for Treatment of 48 Cases of Acute Lumbar Sprain显示文摘AcupunctureCombinedwithPluckingMuscleMethodforTreatmentof48CasesofAcuteLumbarSprain￥YangTonghua;HuChanghai;QiRuihong(CentralH... | Yang Tonghua Hu Changhai Qi Ruihong(Central Hospital of Mudanjiang Administrative Bureau of Forest,Helongjiang Province) | 1995 | 中国针灸1995，15，S2： | 0 |
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