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| 1 | Retrospective analysis of extra-gastrointestinal stromal tumors显示文摘AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors(EGISTs)in South Korea.METHODS:A total of 51 patients with an EGIST were identified.The clinicopathologic features,including sex,age,location,tumor size,histology,mitotic rate,immunohistochemical features,genetic status and survival data,were analyzed.RESULTS:The median age was 55 years(range:29-80years),and male:female ratio was 1:1.04.The most common site was in the mesentery(n=15)followed by the retroperitoneum(n=13)and omentum(n=8).The median tumor size was 9.0 cm(range:2.6-30.0cm)and the median mitotic rate was 5.0/50HPF.(1/50-185/50).KIT was analyzed in 16,which revealed 10cases with wild-type KIT and 6 cases with an exon 11mutation.Among 51 patients,31 patients had undergone surgery,and 10 had unresectable disease and had taken palliative imatinib,which resulted in 22.7 mo of progression-free survival.Of the patients who had undergone surgery,18 did not take adjuvant imatinib,and 8 of these were categorized as'high risk'according to the risk criteria.However,the relapse-free survival was not different(P=0.157)between two groups.CONCLUSION:Because the biologic behaviors of GISTs differ according to the location of the tumor,a more stratified strategy is required for managing EGISTs including incorporation of molecular features. | Jun Ho Yi Byeong-Bae Park Jung Hun Kang In Gyu Hwang Dong Bok Shin Sun Jin Sym Hee Kyung Ahn Soon Il Lee Do Hyoung Lim Keon Woo Park Young-Woong Won Sung Hee Lim Se Hoon Park | 2015 | World Journal of Gastroenterology2015，21，6： | 9 |
| 2 | A phase II study of sunitinib as a second-line treatment in advanced biliary tract carcinoma: A multicentre, multinational study显示文摘 | Jun Ho Yi Sumitra Thongprasert Jeeyun Lee D.C. Doval Se Hoon Park Joon Oh Park Young Suk Park Won Ki Kang Ho Yeong Lim | 2011 | European Journal of Cancer2011，，2： | 2 |
| 3 | Weekly docetaxel and gemcitabine in previously treated metastatic esophageal squamous cell carcinoma显示文摘AIM: To assess the efficacy and safety of weekly docetaxel plus a fixed-dose rate(FDR) of gemcitabine in metastatic esophageal squamous cell carcinoma(SCC).METHODS: A multi-center, open-label, prospective phase Ⅱ study was designed.Thirty-three esophageal SCC patients with documented progression after fluoropyrimidine/platinum-based first-line chemotherapy were enrolled and treated with docetaxel 35 mg/m2 and gemcitabine 1000 mg/m2 iv at a FDR(10 mg/m2 per minute) on days 1 and 8.Treatment was repeatedevery twenty-one days until disease progression, unacceptable toxicity, or consent withdrawal.The primary endpoint was response rate(RR), and secondary endpoints were safety, progression-free survival(PFS) and overall survival(OS).RESULTS: Combination of weekly docetaxel and FDR gemcitabine was well tolerated: the most common treatment-related adverse events were anemia(97%), fatigue(64%) and neutropenia(55%).One patient with multiple lung and lymph node metastases died of respiratory failure after receiving four cycles of chemotherapy, and the possibility of drug-induced pneumonitis could not be completely excluded.Disease control(objective response plus stable disease) in the ITT population was achieved in 88% of patients, and the overall RR was 30%(95%CI: 15%-46%).The median PFS and OS were 4.0(95%CI: 3.4-4.6) and 8.8 mo(95%CI: 7.8-9.8 mo), respectively.CONCLUSION: A combination of weekly docetaxel and FDR gemcitabine showed promising antitumor activity and tolerability in previously treated, metastatic esophageal SCC. | Min-Young Lee Ki Sun Jung Hae Su Kim Ji Yun Lee Sung Hee Lim Moonjin Kim Hyun Ae Jung Sung Min Kim Jong Mu Sun Myung-Ju Ahn Jeeyun Lee Se Hoon Park Seong Yoon Yi In Gyu Hwang Sang-Cheol Lee Hee Kyung Ahn Do Hyoung Lim Soon Il Lee Keon Woo Park | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 4 | A developmental mechanism of spontaneous reattachment in rhegmatogenous retinal detach- ment 显示文摘 | Chung SE Kang SW Yi CH | 2012 | Korean J Ophthalmol2012，26，： | 1 |
| 5 | Lipodystrophia centri-fugalis abdominalis in Korea显示文摘 | Chang SE Bae GY Jeong YI | | 0，，： | 1 |
| 6 | Functional activation of macrophages, monocytes and splenic lymphocytes by polysaccharide fraction from Tricholoma matsutake显示文摘 | Se Eun Byeon Jaehwi Lee Eunji Lee Song Yi Lee Eock Kee Hong Young Eon Kim Jae Youl Cho | 2009 | Archives of Pharmacal Research2009，，11： | 1 |
| 7 | Incidence and risk factors of infection caused by vancomyein-resistant enterococcus colonization in neurosur- gical intensive care unit patients 显示文摘 | Se YB Chun HJ Yi HJ | 2009 | J Korean Neurosurg Soc2009，46，2： | 1 |
| 8 | Stigma developmentand receptivity in almond (Prunus dulcia) 显示文摘 | Yi WG Law SE McCoyD | 2006 | Annals of Botany2006，97，1： | 1 |
| 9 | Case of cutaneous metastasis from intracranial hemangiopericytoma 显示文摘 | Jeong YI Chang SE Lee MW | 2005 | Int J Dermatol2005，44，10： | 1 |
| 10 | Müllerian inhibiting substance signaling uses a bone morphogenetic protein(BMP)-like pathway mediated by ALK2 and induces smad6 expression显示文摘 | Clarke TR Hoshiya Y Yi SE | 2001 | Mol Endoerinol2001，15，6： | 1 |
| 11 | Chitosan-g-mPEG- supported palladium (0) catalyst for Suzuki cross-couplingreaction in water显示文摘 | Sin Eunyoung Yi Song Se Lee Yoon Sik | 2010 | Journal of Molecular Catalysis A: Chemica2010，315，1： | 1 |
| 12 | Definitive chemoradiation therapy with capecitabine in locally advanced pancreatic cancer显示文摘 | Hyo Song Kim Seong Yoon Yi Hyun Jung Jun Jeeyun Lee Se Hoon Park Jong Kyun Lee Kyu Taek Lee Kwang Hyuck Lee Dong Wook Choi Seong-Ho Choi Jin Seok Heo Young Suk Park Ho Yeong Lim Won Ki Kang Hee Chul Park Do Hoon Lim Joon Oh Park | 2010 | Anti-Cancer Drugs2010，，1： | 1 |
| 13 | Lipodystrophia centrifugalis abdominalis in Korea显示文摘 | Chang SE Bae GY Jeong YI | 2004 | Pediatr Dermatol2004，21，5： | 1 |
| 14 | A phase I North Central Treatment Group Trial-N9923 of escalating doses of twice-daily thoracic radiation therapy with alternating chemotherapy in limited-stage small lung cancer(LSCLC)显示文摘 | Garces YI Okuno SH Schild SE | 2007 | Int J Radiat Oncol Biol Phys2007，67，4： | 1 |
| 15 | Case of cutaneous metastasis fi'om intracranial hemangiopericytoma显示文摘 | Jeong YI Chang SE Lee MW | 2005 | Int J Dermatol2005，44，10： | 1 |
| 16 | Lipodystrohia centrifugalis abdom-inalis in Korea显示文摘 | Chang SE Bae GY Jeong YI | 2004 | Pediatr Dermatol2004，21，5： | 1 |
| 17 | The role of Src kinase in macrophage-mediated inflammatory responses显示文摘 | Byeon SE Yi YS Oh J etal | 2012 | Mediators Inflamm2012，2012，51： | 1 |
| 18 | The hypothalamic clock and its control of glucose homeostasis显示文摘 | Kalsbeek A Yi CX La Fleur SE | 2010 | Trends Endocrinol Metab2010，21，7： | 1 |
| 19 | Biliary Complications in Living Donor Liver Transplantation: Imaging Findings and the Roles of Interventional Procedures显示文摘 | Jung Min Chang Jeong Min Lee Kyung Suk Suh Nam Joon Yi Yong Tae Kim Se Hyung Kim Joon Koo Han Byung Ihn Choi | 2005 | CardioVascular and Interventional Radiology2005，，6： | 1 |
| 20 | Design, Syntheses and biological evaluations of nonpeptidic caspase 3 Inhibitors显示文摘 | Kim ES Yoo SE Yi KY | 2002 | Bull Korean Chem Soc2002，23，7： | 1 |
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