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| 1 | AFP level and histologic differentiation predict the survival of patients with liver transplantation for hepatocellular carcinoma显示文摘BACKGROUND: In liver transplantation or resection for hepatocellular carcinoma (HCC), patient selection depends on morphological features. In patients with HCC, we performed a clinicopathological analysis of risk factors that affected survival after liver transplantation. METHODS: In 389 liver transplantations performed from 2004 to 2010, 102 were for HCC patients. Data were collected retrospectively from the Organ Transplantation Center Database. Variables were as follows: age, gender, preoperative alpha-fetoprotein (AFP) levels, Child-Pugh and MELD scores, prognostic staging criteria (Milan and UCSF), etiology, number of tumors, the largest tumor size, total tumor size, multifocality, intrahepatic portal vein tumor thrombosis, bilobarity, and histological differentiation. RESULTS: One hundred and two patients were evaluated. The 5-year overall survival rate was 56.5%. According to the UCSF criteria, 63% of the patients were within and 37% were beyond UCSF (P=0.03). Ten patients were excluded (one with fibrolamellary HCC and 9 because of early postoperative death without HCC recurrence), and 92 patients were assessed. The mean age of the patients was 56.5±6.9 years. Sixty-two patients underwent living donor liver transplantations. The mean follow-up time was 29.4±22.6 months. Fifteen patients (16.3%) died in the follow-up period due to HCC recurrence. Univariate analysis showed that AFP level, intrahepatic portal vein tumor thrombosis, histologic differentiation and UCSF criteria were significant factors related to survival and tumor recurrence. The 5-year estimated overall survival rate was 62.2% in allpatients. According to the UCSF criteria, and the 5-year overall survival rate was 66.7% within and 52.7% beyond the criteria (P=0.04). Multivariate analysis showed that AFP level and poor differentiation were independent factors. CONCLUSIONS: For proper patient selection in liver trans- plantation for HCC, prognostic criteria related to tumor biology (especially AFP level and histological differentiation) should be considered. Poor differentiation and higher AFP levels are indicators of poor prognosis after liver transplantation. | Onur Yaprak Murat Akyildiz Murat Dayangac Baha Tolga Demirbas Necdet Guler Gulen Bulbul Dogusoy Yildiray Yuzer Yaman Tokat | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 15 |
| 2 | Major complications of adult right lobe living liver donors显示文摘BACKGROUND:The right lobe of the liver is generally preferred for living donor liver transplantation in adult patients with end-stage liver disease.It is important to know the preoperative factors relating to the major postoperative complications.We therefore evaluated the possible risk factors for predicting postoperative complications in right lobe liver donors.METHODS:Data from 378 donors who had undergone | Necdet Guler Onur Yaprak Yusuf Gunay Murat Dayangac Murat Akyildiz Fisun Yuzer Yildiray Yuzer Yaman Tokat | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，2： | 3 |
| 3 | Living donor liver hilar variations: surgical approaches and implications显示文摘BACKGROUND: Varied vascular and biliary anatomies are common in the liver. Living donor hepatectomy requires precise recognition of the hilar anatomy. This study was undertaken to study donor vascular and biliary tract variations, surgical approaches and implications in living liver transplant patients. METHODS: Two hundred living donor liver transplantations were performed at our institution between 2004 and 2009. All donors were evaluated by volumetric computerized tomography (CT), CT angiography and magnetic resonance cholangiography in the preoperative period. Intraoperative ultrasonography and cholangiography were carried out. Arterial, portal and biliary anatomies were classified according to the Michels, Cheng and Huang criteria. RESULTS: Classical hepatic arterial anatomy was observed in 129 (64.5%) of the 200 donors. Fifteen percent of the donors had variation in the portal vein. Normal biliary anatomy was found in 126 (63%) donors, and biliary tract variation in 70% of donors with portal vein variations. In recipients with single duct biliary anastomosis, 16 (14.4%) developed biliary leak, and 9 (8.1%) developed biliary stricture; however more than one biliary anastomosis increased recipient biliary complications. Donor vascular variations did not increase recipient vascular complications. Variant anatomy was not associated with an increase in donor morbidity. CONCLUSIONS: Living donor liver transplantation provides information about variant hilar anatomy. The success of the procedure depends on a careful approach to anatomical variations. When the deceased donor supply is inadequate living donor transplantation is a life-saving alternative and is safe for the donor and recipient, even if the donor has variant hilar anatomy. | Onur Yaprak Tolga Demirbas Cihan Duran Murat Dayangac Murat Akyildiz Yaman Tokat Yildiray Yuzer | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，5： | 2 |
| 4 | Credit Risk and the Term Structure of Lease Rates: A Reduced Form Approach显示文摘 | Brent W. Ambrose Yildiray Yildirim | 2008 | The Journal of Real Estate Finance and Economics2008，，3： | 1 |
| 5 | M echanieal Charac- terization of Flocked Fabric for Automobile Seat Cover显示文摘 | Kadir Bilisik Qguz Demiryurek and Yildiray Turhan | 2011 | Fibers and Polymers2011，12，1： | 1 |
| 6 | Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aor- tic athemsclerosis显示文摘 | Mustafa Gtir Durmus Yildiray Sahin Zafer Elbasan | 2013 | Journal of Cardiology2013，61，2： | 1 |
| 7 | Retrograde intrarenalsurgery versus percutaneous nephrolithotomy in the managementof lowerpole renal stones with a diameter of 15 to 20 mm显示文摘 | Omer BF Berkan R Yildiray Y | 2011 | JEndourol2011，25，7： | 1 |
| 8 | Geochemical assessment of Smav geothermal field, Turkey 显示文摘 | Yildiray Palabiyik Umran Serpen | 2008 | Revista Mexicana Geolog icas2008，25，3： | 1 |
| 9 | Adap- tive Posicast Controller for Time-delay Systems with Relative De- gree n * ≤2 显示文摘 | YILDIRAY Y ANNASWAMY A KOLMANOVSKY 1 V | 2010 | Automatica2010，46，3： | 1 |
| 10 | Prevalence of fusion and gemi- nation in permanent teeth in Coppadocia region in Turkey显示文摘 | Ahmet ES Yildiray S Yasin Y | 2011 | Pak Oral Dent2011，，： | 1 |
| 11 | Leverage options liabilities and corporate bond pricing显示文摘 | Hongming Huang?Yildiray Yildirim | | 0，，： | 1 |
| 12 | Effect of wrinkle resistance finish on cotton fabric properties显示文摘 | YAHYA C MUHAMMET A YILDIRAY T | 2009 | Indian Journal of Fibre & Textile Research2009，34，： | 1 |
| 13 | Leverage options liabilities and corporate bond pricing显示文摘 | Hongming Huang?Yildiray Yildirim | | 0，，： | 1 |
| 14 | Pricing Treasury Inflation Protected Securities and Related Derivatives using an HJM Model 显示文摘 | Robert Jarrow and Yildiray Yildirim | 2002 | February 192002，，： | 1 |
| 15 | Price discovery in real estate markets: a dynamic analysis 显示文摘 | ABDULLAH YAVAS YILDIRAY YILDIRIM | 2011 | Journal Real Estate Finance Econ2011，42，： | 1 |
| 16 | Geochemical assessment of Simav geo- thermal field , turkey 显示文摘 | Yildiray P Umran S | 2008 | Revista Mexicana de Ciencias Geu16gicas2008，25，3： | 1 |
| 17 | Mandibular asymmetry in Class II subdivision malocclusion 显示文摘 | Gokmen K Tancan U Yildiray S | 2008 | Angle Orthod2008，78，1： | 1 |
| 18 | Simulation of an enhanced gas recovery field trial tbr coal mine gas management 显示文摘 | Russell Packham Yildiray Cinar Roy Moreby | 2011 | International Journal of Coal Geology2011，85，34： | 1 |
| 19 | Histogram based perceptual qualityassess-ment method for color images 显示文摘 | Yalman Yildiray | 2014 | Computer Standard S & Interfaces2014，36，6： | 1 |
| 20 | An evaluation of low molecular weight heparin and hyperbaric oxygen treatment in the prevention of intra-abdominal adhesions and wound healing显示文摘 | Soykan Arikan Gokhan Adas Gul Barut Akin Savas Toklu Ahmet Kocakusak Hafize Uzun Ozgur Kemik Yildiray Daduk Seval Aydin Sevim Purisa | 2005 | The American Journal of Surgery2005，，2： | 1 |
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