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| 1 | Effect of Qingyitang on activity of intracellular Ca^(2+)-Mg^(2+)-ATPase in rats with acute pancreatitis显示文摘AIM: To study the change of intracellular calcium-magnesium ATPase (Ca^2+-Mg^2+-ATPase) activity in pancreas, liver and kidney tissues of rats with acute pancreatitis (AP), and to investigate the effects of Qingyitang (QYT) (Decoction for clearing the pancreas) and tetrandrine (Tet) and vitamin E(VitE) on the activity of Ca^2+-Mg^2+-ATPase. METHODS: One hundred and five Sprague-Dawley rats were randomly divided into: normal control group, AP group,treatment group with QYT (1 ml/100 g) or Tet (0.4 ml/100 g) or VitE (100 mg/kg). AP model was prepared by a retrograde injection of sodium taurocholate into the pancreatic duct. Tissues of pancreas, liver and kidney of the animals were taken at 1 h, 5 h, 10 h respectively afer AP induction, and the activity of Ca^2+-Mg^2+-ATPase was studied using enzymehistochemistry staining. Meanwhile, the expression of Ca^2^+-Mg^2+-ATPase of the tissues was studied by RT-PCR. RESULTS: The results showed that the positive rate of Ca^2+-Mg^2+-ATPase in AP group (8.3%, 25%, 29.2%) was lower than that in normal control group (100%) in all tissues(P<0.01), the positive rate of Ca^2+-Mg^2+-ATPase in treatment group with QYT (58.3%, 83.3%, 83.3%), Tet (50.0%,70.8%, 75.0%) and VitE (54.2%, 75.0%, 79.2%) was higher than that in AP group (8.3%, 25.0%, 29.2%) in all tissues(P<0.01). RT-PCR results demonstrated that in treatment groups Ca^2+-Mg^2+-ATPase gene expression in pancreas tissue was higher than that in AP group at the observing time points, and the expression at 5 h was higher than that at 1 h. The expression of Ca^2+-Mg^2+-ATPase in liver tissue was positive, but without significant difference between different groups. CONCLUSION: The activity and expression of intracellular Ca^2+-Mg^2+-ATPase decreased in rats with AP, suggesting that Ca^2+-Mg^2+-ATPase may contribute to the occurrence and development of cellular calcium overload in AP. QYT, Tet and VitE can increase the activity and expression of Ca^2+-Mg^2+-ATPase and may relieve intracellular calcium overload to protect the tissue and cells from injuries. | YingQiu Yong-YuLi Shu-GuangLi Bo-GenSong Gui-FenZhao | 2004 | World Journal of Gastroenterology2004，10，1： | 22 |
| 2 | Age-dependent branching processes in random environments显示文摘We consider an age-dependent branching process in random environments. The environments are represented by a stationary and ergodic sequence ξ = (ξ0,ξ1,...) of random variables. Given an environment ξ, the process is a non-homogenous Galton-Watson process, whose particles in n-th generation have a life length distribution G(ξn) on R+, and reproduce independently new particles according to a probability law p(ξn) on N. Let Z(t) be the number of particles alive at time t. We first find a characterization of the conditional probability generating function of Z(t) (given the environment ξ) via a functional equation, and obtain a criterion for almost certain extinction of the process by comparing it with an embedded Galton-Watson process. We then get expressions of the conditional mean EξZ(t) and the global mean EZ(t), and show their exponential growth rates by studying a renewal equation in random environments. | LI YingQiu LIU QuanSheng | 2008 | Science China Mathematics2008，51，10： | 12 |
| 3 | Diffusion occupation time before exiting显示文摘 | Yingqiu LI Suxin WANG Xiaowen ZHOU Na ZHU | 2014 | Frontiers of Mathematics in China2014，9，4： | 9 |
| 4 | Clinical study of paclitaxel plus cisplatin in the treatment of recurrent cervical cancer显示文摘Objective: To observe the efficacy and toxicities of paclitaxel plus cisplatin in the treatment of recurrent cervical cancer. Methods: Twenty-three patients with a diagnosis of recurrent cervical cancer were eligible. Three-weekly chemo- therapy regimen consisted of paclitaxel 135–150 mg/m2 infusion for 3 h on day 1, cisplatin 25 mg/m2 infusion on day 1 to 3. All patients received at least two cycles treatment. Results: The response rates was 47.8%, including CR 2 cases (8.7%), PR 9 cases (39.1%). The major toxicity included neutropenia, nausea vomiting, arthralgia, myalgia and alopecia. Conclusion: Paclitaxel combined with cisplatin is an effective therapy with acceptable adverse reactions for recurrent cervical cancer. | Yingqiu Song Guiling Li Fang Zhu Fangzheng Zhou Sheng Zhang Jing Wang Zhongyuan Ying | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，3： | 9 |
| 5 | Integrated Chinese-western therapy versus western therapy alone on survival rate in patients with non-small-cell lung cancer at middlelate stage显示文摘OBJECTIVE: To compare the effects of integrated Chinese-Western therapy versus Western therapy alone on the survival rate of patients with non-small-cell lung cancer (NSCLC) at middle-late stage and to evaluate prognostic factors. METHODS: We selected 98 inpatients with middle-late stage NSCLC diagnosed from March 2009 to March 2011 and randomly divided them into two groups, with 49 cases in each group, and the clinical data were analyzed retrospectively.The control group was treated by the combined methods of Western Medicine, including chemotherapy, supportive treatment and symptomatic treatment. The observation group was treated by injection and prescriptions of Chinese medicine based on Traditional Chinese Medicine syndrome differentiation and by the same combined methods of western treatment used in the control group. After treatment, the survival rates of the patients were compared by the stage of cancer and evaluation of 24 prognostic factors analyzed by a Cox regressionmodel, and the clinical data were statistically analyzed. RESULTS: The survival rates of all patients were over 90.0% at 1 and 3 months after treatment with no significant differences between the two groups (P>0.05); In the observation group the survival rates at 6 months and 1 year were 93.4% and 42.8%, respectively, being superior to 85.6% and 18.3% in the control group (P<0.05). The median survival time in the observation group was superior to the control group (P<0.05); The effects of 24 prognostic factors were significantly better in the observation group than in the control group (P<0.05). CONCLUSION: Integrated Chinese-western therapy can significantly improve the survival rate in patients with middle-late stage NSCLC and improve prognostic factors compared with western therapy alone. | Guoqiang Lin Yingqiu Li Shengxi Chen Haihe Jiang | 2013 | Journal of Traditional Chinese Medicine2013，33，4： | 7 |
| 6 | Attenuated phenotypes and analysis of a herpes simplex virus 1strain with partial deletion of the UL7, UL41 and LAT genes显示文摘We previously constructed a herpes simplex virus 1(HSV-1) UL7 mutant virus(M1) and showed that a partial deletion mutation of the UL7 gene led to a lower proliferative rate and an attenuated phenotype. Using the M1 mutant, we further modified the UL41 gene, which encodes another tegument protein, and the latency-associated transcript(LAT) gene. Observations of the resulting mutants with modified UL7 and UL41(M2) or UL7, UL41 and LAT(M3) genes indicated attenuated phenotypes, with lower proliferative ratios in various cells, non-lethal infections in mice and lower viral loads in nervous tissues compared with the wild-type strain. Furthermore, no LAT stable intron could be detected in the trigeminal ganglion of M3-infected animals. The results obtained with the three HSV-1 mutants indicate that the M3 mutant is an attenuated strain with low pathogenicity during both acute and latent infections. Together, the results support the use of the M3 mutant as a candidate for the development of an HSV-1 vaccine. | Xingli Xu Yingqiu Guo Shengtao Fan Pingfang Cui Min Feng Lichun Wang Ying Zhang Yun Liao Xiaolong Zhang Qihan Li | 2017 | Virologica Sinica2017，32，5： | 6 |
| 7 | An occupation time related potential measure for diffusion processes显示文摘在这份报纸同类的散开过程,李·伊的途径和 X. 周[统计员。Probab。Lett, 2014, 94:48-55 ] 被采用发现被他们的关节打折的潜在的措施的表情在半无限的间隔上的职业时间(,) 并且(,) :结果以与散开联系的微分方程的答案被表示发电机。使用这些结果,我们获得更多为 Brownian 的明确的表情有飘移,斜 Brownian 运动,和 Brownian 运动与的运动两价分别地漂流。 | Ye CHEN Yingqiu LI Xiaowen ZHOU | 2017 | Frontiers of Mathematics in China2017，12，3： | 4 |
| 8 | Neutrophil elastase:From mechanisms to therapeutic potential显示文摘Neutrophil elastase(NE),a major protease in the primary granules of neutrophils,is involved in microbicidal activity.NE is an important factor promoting inflammation,has bactericidal effects,and shortens the inflammatory process.NE also regulates tumor growth by promoting metastasis and tumor microenvironment remodeling.However,NE plays a role in killing tumors under certain conditions and promotes other diseases such as pulmonary ventilation dysfunction.Additionally,it plays a complex role in various physiological processes and mediates several diseases.Sivelestat,a specific NE inhibitor,has strong potential for clinical application,particularly in the treatment of coronavirus disease 2019(COVID-19).This review discusses the pathophysiological processes associated with NE and the potential clinical applications of sivelestat. | Weilin Zeng Yingqiu Song Runze Wang Rong He Tianlu Wang | 2023 | Journal of Pharmaceutical Analysis2023，13，4： | 4 |
| 9 | Asymptotic properties branching processes in of supercritical random environments显示文摘 | Yingqiu LI Quansheng LIU Zhiqiang GAO Hesong WANG | 2014 | Frontiers of Mathematics in China2014，9，4： | 3 |
| 10 | FeCe nanocomposite with high iron content as efficient catalyst for generation of COx-free hydrogen via ammonia decomposition显示文摘FeCe nanocomposite catalysts with different iron contents were synthesized by a facile co-precipitation method.The as-prepared materials were characterized by various techniques including powder X-ray diffraction(XRD),N2 adsorption/desorption and high-resolution transmission electron microscopy(HRTEM).Catalyst with the highest iron content(90 FeCe) shows the best activity for the hydrogen generation via ammonia decomposition.83% NH3 conversion is achieved at 550℃ and nearly full conversion of NH3 is realized at 600℃ with a GHSV of 24000 cm3/(gcat·h).The large content and small size crystal particles of iron species are responsible for the good catalytic performance.Temperatureprogrammed reduction by hydrogen(H2-TPR) was performed to investigate the interaction between cerium and iron species.It is found that slight cerium can exert strong interaction with iron compound thus effectively prevent the self-aggregation of active iron species,so as to improve the catalytic activity for ammonia decomposition. | Yingqiu Gu Xiaoya Chen Shuang Zhao Yuting Zhang | 2020 | Journal of Rare Earths2020，38，10： | 3 |
| 11 | Testing three pipelines for 18S rDNA-based metabarcoding of soil faunal diversity显示文摘A number of basic and applied questions in ecology and environmental management require the characterization of soil and leaf litter faunal diversity. Recent advances in high-throughput sequencing of barcode-gene amplicons ('metabarcoding') have made it possible to survey biodiversity in a robust and efficient way. However, one obstacle to the widespread adoption of this technique is the need to choose amongst many candidates for bioinformatic processing of the raw sequencing data. We compare three candidate pipelines for the processing of 18S small subunit rDNA metabarcode data from solid substrates: (i) USEARCH/CROP, (ii) Denoiser/UCLUST, and (iii) OCTUPUS. The three pipelines produced reassuringly similar and highly correlated assessments of community composition that are dominated by taxa known to characterize the sampled environments. However, OCTUPUS appears to inflate phylogenetic diversity, because of higher sequence noise. We therefore recommend either the USEARCH/CROP or Denoiser/UCLUST pipelines, both of which can be run within the QIIME (Quantitative Insights Into Microbial Ecology) environment. | YANG ChenXue JI YingQiu WANG XiaoYang YANG ChunYang YU Douglas W. | 2013 | Science China(Life Sciences)2013，56，1： | 2 |
| 12 | 泰山黄精:作为中药的营养价值、草药酶的来源和潜在的营养价值和有效性显示文摘近年来,中药治疗在抗击COVID-19取得成功疗效,黄胡连(黄精)的加工产品具有抗糖尿病、抗病毒、抗肿瘤、抗氧化、抗疲劳、抗衰老和增强免疫的作用,是推荐成分之一。泰山气候温和,森林茂密适合多根根茎的生长,已逐渐进化为一种独特的物种。考虑到泰山的重要药用价值和宜人的口感,可以开发出具有抗COVID-19潜力的质量标志物控制的各种健康、功能食品和应急食品。本研究旨在回顾目前泰山黄精的营养价值及其作为中药、草药酶来源、治疗COVID-19和食物短缺的潜在治疗剂的证据。关于草药纳米医学的最新发现表明,纳米级化合物在药物传递或纳米酶催化生物加工中有潜在的效率。 | Lazzat Nurtay 孙庆雷 牟成林 曹仲山 王倩 梁宗锁 马翠萍 李旭刚 Amr Amin Yingqiu Xie | 2021 | Acupuncture and Herbal Medicine2021，1，1： | 2 |
| 13 | Fabrication and properties of ultraviolet photo-detectors based on SiC nanowires显示文摘A new type of ultraviolet photo-detectors (UVPDs) based on a bundle of highly aligned SiC nanowires was fabricated and the photo-electric properties of the UVPDs including I-V characteristics and time response were studied in this work. SiC nanowires were prepared by pyrolysis of a polymer precursor with ferrocene as the catalyst by a CVD route. The diameters of SiC nanowires varied from 100 to 200 nm while they were some centimeters long and the SiC nanowires were with zinc blended cubic form ( -SiC) tested by X-ray diffraction. A bundle of nanowires was fixed onto two legs' base by conductive silver paste to form the UVPDs. The electrical measurement of the device showed a significant increase of current when the device was exposed to 254 nm UV light, and the rising time of the device is very short, but the falling time is relatively long. Our results show that the UVPDs based on SiC nanowires have excellent electrical and optical properties which can be potentially applied. | PENG Gang ZHOU YingQiu HE YanLan YU XiaoYan LI GongYi | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，7： | 2 |
| 14 | Coat protein promoter from cotton leaf curl virus is not a tissue-specifically expressed promoter显示文摘Geminivirus is a kind of single-stranded DNA virus. Experimental results from tomato golden mosaic virus (TGMV) showed that expression pattern of coat protein gene (cp) promoter was phloem specifically expressed. In this note, the studies on cp promoter of cotton leaf curl virus (CLCuV) which is found and identified recently suggest that the promoter is not phloem specifically expressed. The expressing activity of gus gene driven by the promoter exists not only in phloem but also in mesophyll tissues and root tip meristem. Transient expression suggests that cp promoter transactivated by AC2 shows expressing activity in mesophyll and vascular tissue of leaf vein. | XIE Yingqiu ZHU Zhen LIU Yule WU Qian XU Honglin | 2000 | Chinese Science Bulletin2000，45，20： | 2 |
| 15 | Exact Vacuum Solutions to the Einstein Equation显示文摘在这篇论文,作者为得到一系列准确真空答案到爱因斯坦方程介绍一个框架。分辨率的这个过程基于度量标准的一种正规形式。根据这个过程,爱因斯坦方程能被归结为一些 2-dimensional 象 Laplace 一样方程或旋转;分叉方程,它对决定方便。 | Yingqiu GU | 2007 | Chinese Annals of Mathematics,Series B2007，28，5： | 1 |
| 16 | Illness behavior and patient satisfaction as correlates of self-referral in Japan显示文摘 | Yingqiu Guo Toshihide Kurokia Seiji Yamashiro | 2007 | Family Practice2007，19，4： | 1 |
| 17 | UV-induced SiC nanowire sensors显示文摘 | Gang Peng Yingqiu Zhou Yanlan He | 2015 | JournMoPbysJcs D: AppliedPhysics2015，48，5： | 1 |
| 18 | Inactivation of soybean lipoxygenase in soymilk by pulsed electric fields 显示文摘 | Li Yingqiu Chen Qun Liu Xiuhe | 2008 | Food Chemistry2008，109，2： | 1 |
| 19 | The continuity of college students' autonomous learning motivation and its predictors: A three year longitudinal, study显示文摘 | Yingqiu Pan Mary Gauvain | 2012 | Learning and Individual Differences2012，22，1： | 1 |
| 20 | Effects of pulsed electric fields on physicochemical properties of soybean protein isolates显示文摘 | Yingqiu Li Zhengxin Chen Haizhen Mo | 2007 | LWT-Food Science and Technology2007，40，7： | 1 |
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