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16篇 您的检索式:作者名="Yingchao Du"
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1High power THz source based on coherent radiation of picosecond relativistic electron bunch train显示文摘Tunable and compact high power terahertz (THz) radiation based on coherent radiation (CR) of the picosecond relativistic electron bunch train is under development at the Tsinghua accelerator lab. Coherent synchronization radiation (CSR) and coherent transition radiation (CTR) are researched based on an S-band compact electron linac, a bending magnet or a thin foil. The bunch train's form factors, which are the key factor of THz radiation, are analyzed by the PARMELA simulation. The effects of electron bunch trains under different conditions, such as the bunch number, bunch charges, micro-pulses inter-distance, and accelerating gradient of the gun are investigated separately in this paper. The optimal radiated THz power and spectra should take these factors as a whole into account.YOU Yan YAN LiXin DU YingChao HUA JianFei HUANG WenHui TANG ChuanXiang 2011Science China(Physics,Mechanics & Astronomy)2011,54,S2:6
2Bioactive glass coatings on metallic implants for biomedical applications显示文摘Metallic implant materials possess adequate mechanical properties such as strength,elastic modulus,and ductility for long term support and stability in vivo.Traditional metallic biomaterials,including stainless steels,cobalt-chromium alloys,and titanium and its alloys,have been the gold standards for load-bearing implant materials in hard tissue applications in the past decades.Biodegradable metals including iron,magnesium,and zinc have also emerged as novel biodegradable implant materials with different in vivo degradation rates.However,they do not possess good bioactivity and other biological functions.Bioactive glasses have been widely used as coating materials on the metallic implants to improve their integration with the host tissue and overall biological performances.The present review provides a detailed overview of the benefits and issues of metal alloys when used as biomedical implants and how they are improved by bioactive glass-based coatings for biomedical applications.Joy-anne N.Oliver Yingchao Su Xiaonan Lu Po-Hsuen Kuo Jincheng Du Donghui Zhu 2019Bioactive Materials2019,4,1:4
3Improved mechanical, degradation, and biological performances of Zn–Fe alloys as bioresorbable implants显示文摘Zinc(Zn)is a promising bioresorbable implant material with more moderate degradation rate compared to magnesium(Mg)and iron(Fe).However,the low mechanical strength and localized degradation behavior of pure Zn limit its clinical applications.Alloying is one of the most effective ways to overcome these limitations.After screening the alloying element candidates regarding their potentials for improvement on the degradation and biocompatibility,we proposed Fe as the alloying element for Zn,and investigated the in vitro and in vivo performances of these alloys in both subcutaneous and femoral tissues.Results showed that the uniformly distributed secondary phase in Zn–Fe alloys significantly improved the mechanical property and facilitated uniform degradation,which thus enhanced their biocompatibility,especially the Zn-0.4Fe alloy.Moreover,these Zn–Fe alloys showed outstanding antibacterial property.Taken together,Zn–Fe alloys could be promising can-didates as bioresorbable medical implants for various cardiovascular,wound closure,and orthopedic applications.Yingchao Su Jiayin Fu Wonsae Lee Shaokang Du Yi-Xian Qin Yufeng Zheng Yadong Wang Donghui Zhu 2022Bioactive Materials2022,7,11:3
4Warm dense matter research at HIAF显示文摘The research activities on warm dense matter driven by intense heavy ion beams at the new project High Intensity heavy-ion AcceleratorFacility (HIAF) are presented. The ion beam parameters and the simulated accessible state of matter at HIAF are introduced, respectively. Theprogresses of the developed diagnostics for warm dense matter research including high energy electron radiography, multiple-channel pyrometer,in-situ energy loss and charge state of ion detector are briefly introduced.Rui Cheng Yu Lei Xianming Zhou Yuyu Wang Yanhong Chen Yongtao Zhao Jieru Ren Lina Sheng Jiancheng Yang Zimin Zhang Yingchao Du Wei Gai Xinwen Ma Guoqing Xiao 2018Matter and Radiation at Extremes2018,3,2:2
5Simulation optimization of single-shot continuously time-resolved MeV ultra-fast electron diffraction显示文摘Li Renkai Huang Wenhui Du Yingchao 2011Nucl Instrum Methods Phys Res A2011,637,1:1
6Slice emittance measurement for photocathode RF gun with solenoid scanning and RF deflecting cavity显示文摘The radiation of high-gain short-wavelength free-electron laser depends on the slice transverse emittance of the electron bunch. This essay introduces the method of slice emittance measurement, and shows the brief setup of this experiment using the solenoid scanning and RF deflecting cavity at Tsinghua University. The preliminary experimental results show that the slice rms emittance of the electron bunch generated by photocathode RF gun has considerable variations along the bunch and is typically less than 0.55 mm mrad for the laser rms radius of 0.4 mm.LI Chen HUANG WenHui DU YingChao YAN LiXin TANG ChuanXiang 2011Science China(Physics,Mechanics & Astronomy)2011,54,S2:1
7Visualizing the melting processes in ultrashort intense laser triggered gold mesh with high energy electron radiography显示文摘High-energy electron radiography(HEER)is a promising diagnostic tool for high-energy-density physics,as an alternative to tools such as X/γ-ray shadowgraphy and high-energy proton radiography.Impressive progress has been made in the development and application ofHEER in the past fewyears,and its potential for high-resolution imaging of static opaque objects has been proved.In this study,by taking advantage of the short pulse duration and tunable time structure of high-energy electron probes,time-resolved imaging measurements of high-energy-density gold irradiated by ultrashort intense laser pulses are performed.Phenomena at different time scales frompicoseconds to microseconds are observed,thus proving the feasibility of this technique for imaging of static and dynamic objects.Zheng Zhou Yu Fang Han Chen Yipeng Wu Yingchao Du Zimin Zhang Yongtao Zhao Ming Li Chuanxiang Tang Wenhui Huang 2019Matter and Radiation at Extremes2019,4,6:1
8NIR photosensitizers activated byγ-glutamyl transpeptidase for precise tumor fluorescence imaging and photodynamic therapy显示文摘Photodynamic therapy(PDT),a light triggered therapeutic mode,has been recognized as an attractive treatment for oncotherapy.The phototoxicity to normal tissues during treatment limited the development of PDT owing to the always“on”properties of photosensitizers.Activatable photosensitizers are of great importance for improving the selectivity of PDT.Herein,we regarded the overexpressed GGT(γ-Glutamyl transpeptidase)enzyme in tumor cells as a biomarker and developed an activatable photosensitizer Cy-GGT by decorating a specific recognition moiety of GGT,L-glutamic acid,to a hemicyanine dye based on photosensitizer Cy-NH_(2).Cy-GGT was in the“off”state with negligible fluorescence and suppressed singlet oxygen generation,but it could be specifically hydrolyzed to Cy-NH_(2) in the presence of GGT,accompanied with significant fluorescence recovery and singlet oxygen generation increase under light irradiation.The in vitro and in vivo studies indicated that Cy-GGT was suitable for precise tumor imaging and could work as an efficient photosensitizer for inhibiting tumor growth.Yingchao Chen Xueze Zhao Tao Xiong Jianjun Du Wen Sun Jiangli Fan Xiaojun Peng 2021Science China Chemistry2021,64,5:0
9Transcriptomes of Litopenaeus vannamei reveal modulation of antioxidant system induced by dietary archaeal carotenoids显示文摘Oxidative stress induced by factors such as ammonia nitrogen has become a major issue in shrimp farming.The effects of carotenoids on the growth and antioxidant capability of Litopenaeus vannamei juveniles were investigated in this study using dietary archaeal carotenoids supplementation.For four weeks,shrimp were given diets containing 0 mg/kg(Ctrl)and 55.98 mg/kg(Car)archaeal carotenoids.Dietary archaeal carotenoids significantly enhanced the astaxanthin content in shrimp muscles and carapaces,as well as the superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)activity(P<0.05).The malonaldehyde(MDA)content in Car group significantly decreased(P<0.05).The transcriptome analysis was conducted to determine the molecular processes in response to archaeal carotenoids supplementation.A total of 1536 differentially expressed genes(DEGs)were detected,including 538 upregulated DEGs and 998 downregulated DEGs.GO functional enrichment analysis between Ctrl and Car indicated that 26 GO terms including extracellular region,metabolic process,and proteolysis were enriched.The KEGG pathway enrichment analysis revealed that the amino sugar and nucleotide sugar metabolism,cysteine and methionine metabolism,glycine serine and threonine metabolism,and amino acid biosynthesis were enriched.Archaeal carotenoids influenced the expression of several important genes involved in reactive oxygen species(ROS)generation,Nrf2 signaling,and antioxidant enzymes.Seven DEGs were chosen to confirm the RNA-Seq data using qRT-PCR.The genes and pathways discovered in this work assist to elucidate the molecular processes through which archaeal carotenoid enhances L.vannamei antioxidative system.Wei XIE Guoru DU Honggang DENG Yingchao MA Meirong GAO Hu DUAN Sung YIK YEONG Liying SUI 2023Journal of Oceanology and Limnology2023,41,5:0
104-23 An Initiative Design of High Energy Electron Radiography with Ultrahigh Spatial and Temporal Resolution显示文摘In general, high energy density matter can only be transiently produced in the laboratory on a time scale ofnanoseconds. In addition, the pressure in a high energy density sample exceeds 1 Mbar, thus the hydro-dynamicresponse of the sample is a high expansion velocity in the range of km/s (or m/ns). Therefore diagnostics whichare capable of high time resolution (< ns) and high space resolution (< 10 m) are needed. Here, we present ascheme that uses a high energy electron beam as a probe for dynamic imaging measurements of high energy densityprocesses in materials with spatial, temporal resolution and frame rate in the order of 1 m, 1 ps and 1010 FPS,respectively.The device uses an e-LINAC (electron Linear Accelerator), which can produce electron beams with bunchintensity ranging from a few pC to 100 nC, bunch length and bunch interval of 1 and 100 ps in minimum, respectively.The beam energy can be increased easily from a few MeV to GeV by adding more accelerating sections. Detailscan be found in Ref. [1].Zhao Yongtao Zhang Zimin Gai Wei Du Yingchao Cheng Rui Cao Shuchun Zhao Quantang Zhou Xianming Tang Chuanxiang Zhan Wenlong 2014IMP & HIRFL Annual Report2014,,1:0
114-29 Step-target Design for High Energy Electron Radiography Research显示文摘High energy proton beam has the long penetration length in solid matter and it could produce the radiographsand indicate the tomography and material properties inside of the specimen. Considering the expensive coststo construct a high energy proton accelerator, the other candidate of high energy electron beam becomes moreacceptable[1??3]. Due to the high spatial and temperal resolution of high energy electron beam. It is a power tool todiagnose the inner structure change during the high energy density matter production and the inertial confinementfusion process. In order to study the density resolution of the high energy electron beam radiography, a step-targetwas designed and produced. The structure and the target pictures are shown in Fig. 1 and the Si targets withdifferent slot-width were produced by using the microetch technics.Cheng Rui Zhao Yongtao Zhang Ziming Gai Wei Du Yingchao Cao Shuchun Zhou Xianming Zhao Quantang Shen Xiaokang Zong Yang Wang Yangru Xiao Jiahao Li Haixia 2014IMP & HIRFL Annual Report2014,,1:0
12离子束与等离子体相互作用与高能量密度物理研究新型诊断技术进展显示文摘Plasma as the fourth state of matter widely exists in universe and it is the essential state in the process of Initial Confinement Fusion sciences.Ion beam is a unique tool to understand some special properties of plasma itself form the aspect of kinetic interaction between ion and plasma surrounding.The energy loss of helium ions in a dense plasma relates to the self-heating process in a ICF capsule and the radiation protection by Van Allen Radiation Belt of Earth-self against the solar wind.It is a very interesting topic to carry out the series of experiments applying the ion beam and plasma target together in lab[1,2].Cheng Rui Wang Yuyu Zhou Xianming Lei Yu Chen Yanhong Zhao Yongtao Ren Jieru Gao Fei Hu Zhanghu Zhang Zimin Cao Shuchun Du Yingchao Zhao quantang Wang Younian Ma Xinwen Xiao Guoqing 2017IMP & HIRFL Annual Report2017,,1:0
13In-situ electro-deposition synthesis of MnO_(x)-NiCo_(2)O_(4) monolithic catalyst with rich phase interfaces显示文摘A hierarchically structured MnO_(x)-NiCo_(2)O_(4) monolithic catalyst with rich phase interfaces was designed by a simple,eco-friendly and time-saving in-situ electro-deposition method.The abundance of active oxygen species due to this rich phase interfaces contributed to the excellent benzene combustion performance of MnO_(x)-NiCo_(2)O_(4)-2:2 sample,oxidizing about 90% of benzene(T_(90)) at 198℃ under 12000 h^(-1) gaseous hourly space velocity.This work shed new light on the design of excellent monolithic catalysts,which might pave the way for the industrialization of benzene combustion.Dongdong Wang Yingchao Du Xiaoze Wang Zhaxi Cuo Yunfa Chen 2021Chinese Chemical Letters2021,32,1:0
14Synergetic PVA degradation and H2 evolution in photocatalytic fuel cells using Ag@Fe_(2)O_(3) cathode显示文摘In a dual-chamber photocatalytic fuel cell device,polyvinyl alcohol degradation and H2 evolution were concurrently achieved.The setup involved commercial P25 as the photoanode and Ag@Fe_(2)O_(3) nanoparticles as the cathode.Additionally,the feasibility of a Fentonlike reaction in the cathode,utilizing Fe^(2+)ions and pumped O_(2),was demonstrated.Different cathode materials,polyvinyl alcohol types,and pH values’effects were assessed on device performance.Quenching tests highlighted photoinduced holes(h+)and OH·radicals as pivotal contributions to polyvinyl alcohol degradation.Long-term stability of the device was established through cycling experiments.Likun Sun Kesi Xiong Baoning Zhang Jinghong Fang Yingchao He Min Wang Zhixing Gan Fanglin Du Qiong Sun Liyan Yu Lifeng Dong 2024Frontiers of Chemical Science and Engineering2024,18,1:0
153-18 Research Activities Related to High Energy Density Physics显示文摘High energy density is generally defined as a state with energy content larger than 1011 J/m3,or equivalently with pressure higher than 1 Mbar.High energy density matter widely exists in the universe,like the cores of Jupiter,Sun and Earth,as well as inertial confinement fusion.The creation of high energy density state in the laboratory and the research on its properties are very important in astrophysics,planetary sciences,geophysics,inertial fusion sciences and so on.Related to high energy density physics,we carried out a series of research activities including simulation of the state of warm dense matter at HIAF,ion-plasma interaction,highly charged ions induced nanoscale defect on surface and X-ray emission,as well as developing a new multi-channel pyrometer and high energy electron radiography.Cheng Rui Wang Yuyu Zhou Xianming Lei Yu Zhao Yongtao Hu Zhanghu Zhang Zimin Cao Shuchun Du Yingchao Zhao quantang Chen Yanhong Wang Younian Ma Xinwen Xiao Guoqing 2016IMP & HIRFL Annual Report2016,,1:0
16Blending with transition metals improves bioresorbable zinc as better medical implants显示文摘Zinc(Zn)is a new class of bioresorbable metal that has potential for cardiovascular stent material,orthopedic implants,wound closure devices,etc.However,pure Zn is not ideal for these applications due to its low mechanical strength and localized degradation behavior.Alloying is the most common/effective way to overcome this limitation.Still,the choice of alloying element is crucial to ensure the resulting alloy possesses sufficient mechanical strength,suitable degradation rate,and acceptable biocompatibility.Hereby,we proposed to blend selective transition metals(i.e.,vanadium-V,chromium-Cr,and zirconium-Zr)to improve Zn’s properties.These selected transition metals have similar properties to Zn and thus are beneficial for the metallurgy process and mechanical property.Furthermore,the biosafety of these elements is of less concern as they all have been used as regulatory approved medical implants or a component of an implant such as Ti6Al4V,CoCr,or Zr-based dental implants.Our study showed the first evidence that blending with transition metals V,Cr,or Zr can improve Zn’s properties as bioresorbable medical implants.In addition,three in vivo implantation models were explored in rats:subcutaneous,aorta,and femoral implantations,to target the potential clinical applications of bioresorbable Zn implants.Yingchao Su Jiayin Fu Juncen Zhou Elias Georgas Shaokang Du Yi-Xian Qin Yadong Wang Yufeng Zheng Donghui Zhu 2023Bioactive Materials2023,,2:0
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