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| 1 | Cadmium accumulation and tolerance of two castor cultivars in relation to antioxidant systems显示文摘To investigate the effects of Cd on tolerance and antioxidant activities of castor, two different castor(Ricinus communis L.) cultivars(Zibo No. 5 and Zibo No. 8) were used for a hydroponic experiment(0, 1 and 2 mg/L Cd) and a pot experiment using Cd-contaminated soil(34 mg/kg) with the addition of ethylenedinitrilotetraacetic acid(EDTA). The results indicated that there were significant differences between the two cultivars with respect to Cd uptake in shoots(113–248 mg/kg for Zibo No. 5 and 130–288 mg/kg Zibo No. 8), biomass tolerance indexes(64.9%–74.6% for Zibo No. 5 and 80.1%–90.9% for Zibo No. 8) in the hydroponic experiment and survival rates(0% for Zibo No. 5 and 100% for Zibo No. 8)determined by the addition of EDTA in the pot experiment, suggesting that Zibo No. 8 has higher tolerance than Zibo No. 5. Moreover, the castor cultivars have low bioconcentration factors(4.80% for Zibo No. 5 and 5.43% for Zibo No. 8) and low translocation factors(<1%).Consequently, Zibo No. 8 can participate in Cd phytostabilization in highly Cd-polluted areas. The results indicated that glutathione(GSH) as a non-enzymatic antioxidant, and antioxidant enzymes including superoxide dismutase(SOD), catalase(CAT) and guaiacol peroxidase(GPX), were cultivar- and dose-dependent. The higher tolerance of Zibo No. 8compared with Zibo No. 5 can be attributed to the higher GSH levels in the root and higher GPX activity in the leaf. | Hanzhi Zhang Qingjun Guo Junxing Yang Tongbin Chen Guangxu Zhu Marc Peters Rongfei Wei Liyan Tian Chunyu Wang Deyun Tan Jie Ma Gangming Wang Yingxin Wan | 2014 | Journal of Environmental Sciences2014，26，10： | 15 |
| 2 | Krüppel-like factor 8 is a potential prognostic factor for pancreatic cancer显示文摘 | Wei Yingxin Chen Ge You Lei Zhao Yupei | 2014 | Chinese Medical Journal2014，，5： | 8 |
| 3 | Associations of egg consumption with incident cardiovascular disease and all-cause mortality显示文摘Eggs are nutrient-dense while also loaded with abundant cholesterol, thus making the public hesitant about their consumption.We conducted the study to investigate if egg consumption is associated with incident cardiovascular disease(CVD) and all-cause mortality. Using the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China, we included 102,136 adults free of CVD and assessed their egg consumption with food-frequency questionnaires. CVD endpoints and all-cause mortality were confirmed during follow-ups by interviewing participants or their proxies and checking hospital records/death certificates.The HRs(95% CIs) were calculated using the cohort-stratified Cox regression models. During 777,163 person-years of followup, we identified 4,848 incident CVD and 5,511 deaths. U-shaped associations of egg consumption with incident CVD and allcause mortality were observed. Compared with consumption of 3–<6/week, the multivariable-adjusted HRs(95% CIs) of <1/week and ≥10/week for incident CVD were 1.22(1.11 to 1.35) and 1.39(1.28 to 1.52), respectively. The corresponding HRs(95% CIs) for all-cause mortality were 1.29(1.18 to 1.41) and 1.13(1.04 to 1.24). Our findings identified that both low and high consumption were associated with increased risk of incident CVD and all-cause mortality, highlighting that moderate egg consumption of 3–<6/week should be recommended for CVD prevention in China. | Xue Xia Fangchao Liu Xueli Yang Jianxin Li Jichun Chen Xiaoqing Liu Jie Cao Chong Shen Ling Yu Yingxin Zhao Xianping Wu Liancheng Zhao Ying Li Jianfeng Huang Xiangfeng Lu Dongfeng Gu | 2020 | Science China(Life Sciences)2020，63，9： | 7 |
| 4 | Machine Learning−based Weather Support for the 2022 Winter Olympics显示文摘1.A key support for the 2022 Winter Olympics The XXIV Olympic Winter Games are scheduled to take place from 4 to 22 February 2022,followed by the Paralympic Games from 4 to 13 March,in Beijing and towns in the neighboring Hebei Province,China.Weather plays an extremely important role in the outcome of the games(Chen et al.,2018).It can not only cause a difference between a medal or not,but affect the safety of athletes.Success of the Winter Olympics will greatly depend on weather conditions at the outdoor competition venues,dealing with many weather elements including the snow surface temperature,apparent temperature,gust wind speed,snow,visibility,etc.To ensure that the scheduled games go smoothly,it is imperative to have hourly or even every 10-minutely forecasts as well as updated weather-related risk assessments at the venues for the next 240 hours.So far,the Beijing/Hebei Meteorological Observatory has already started intelligent weather forecasting at 3-km resolution based on the results of numerical weather prediction(NWP)models.However,these experiments have suggested that the current forecasting techniques are incapable of capturing the complex mountain weather variations around some venues.The forecasting capability of NWP is constrained partly by limited knowledge of the local weather mechanisms. | Jiangjiang XIA Haochen LI Yanyan KANG Chen YU Lei JI Lve WU Xiao LOU Guangxiang ZHU Zaiwen Wang Zhongwei YAN Lizhi WANG Jiang ZHU Pingwen ZHANG Min CHEN Yingxin ZHANG Lihao GAO Jiarui HAN | 2020 | Advances in Atmospheric Sciences2020，37，9： | 6 |
| 5 | Biosynthesis of poly-3-hydroxybutyrate with a high molecular weight by methanotroph from methane and methanol显示文摘Poly-3-hydroxybutyrate (哲学学士) 能被细菌的各种各样的种类生产。在可能的碳来源之中,甲烷和甲醇能是为哲学学士的生产的合适的底层。甲烷不仅象天然气,而且作为简历气体便宜、丰富。甲醇能也处于一些条件维持 methanotrophic 活动。methanotrophic 紧张 Methylosinus trichosporium IMV3011 能在一个简短非无菌的过程与甲烷和甲醇积累哲学学士。液体甲醇(0.1%) 被增加改进甲烷的氧化。研究用饮料烧瓶被执行。耕作在二个阶段被执行:在除了在批文化的必要营养素(铵,硝酸盐,磷,铜,铁(III ) ,镁或乙烯肼 tetraacetate (EDTA )) 的条件下面的一个连续生长阶段和一个哲学学士累积阶段。细胞的最合适的生长时间是 144 h,这被发现。然后,为第二个阶段的一个优化文化条件被决定,在哪个 PHB 集中能是增加到 0.6 g/L 的大部分。为了增加,哲学学士满意的、柠檬性的酸作为 tricarboxylic 酸周期(TCA ) 的一个禁止者被增加。柠檬性的酸为 PHB 累积是有利的,这被发现,并且 PHB 收益被增加到 40%(w/w ) 从在滋养的缺乏耕作以后的 12% 的起始的收益(w/w ) 。生产的哲学学士具有与直到 1.5 × 1 的分子的重量很高质量 0 6 Da。 | Yingxin Zhang Jiaying Xin Linlin Chen Hao Song Chungu Xia | 2008 | Journal of Natural Gas Chemistry2008，17，1： | 5 |
| 6 | Effects of GS3 and GL3.1 for Grain Size Editing by CRISPR/Cas9 in Rice显示文摘Grain size is one of key agronomic traits associated with grain yield and grain quality. Both major quantitative trait loci GS3 and GL3.1 play a predominant role in negative regulation of grain size. In this study, a CRISPR/Cas9-mediated multiplex genome editing system was used to simultaneously edit GS3 and GL3.1 in a typical japonica rice Nipponbare. In T1 generation, we found that gs3 formed slender grain with lower chalkiness percentage, while gs3gl3.1 produced larger grain with higher chalkiness percentage. In terms of other agronomic traits, flag leaf size, grain number and grain yield of both gs3 and gs3gl3.1 mutants were affected. It is noteworthy that gs3 and gs3gl3.1 mutants both led to dramatical reduction of grain number, thereby decreased grain yield. In conclusion, these results indicated that knockout of GS3 and GL3.1 could rapidly improve grain size, but probably have some negative influences on grain quality and grain yield. | Chen Yuyu Zhu Aike Xue Pao Wen Xiaoxia Cao Yongrun Wang Beifang Zhang Yue Shah Liaqat Cheng Shihua Cao Liyong Zhang Yingxin | 2020 | Rice science2020，27，5： | 4 |
| 7 | PrP mutants with different numbers of octarepeat sequences are more susceptible to the oxidative stress显示文摘One of the physiological functions of cellular prion protein(PrP C )is believed to work as a cellular resistance to oxidative stress,in which the octarepeats region within PrP plays an important role.However,the detailed mechanism is less clear.In this study,the expressing plasmids of wild-type PrP (PrP-PG5)and various PrP mutants containing 0(PrP-PG0),9(PrP-PG9)and 12(PrP-PG12)octarepeats were generated and PrP proteins were expressed both in E.coli and in mammalian cells.Protein aggregation and formation of carbonyl groups were clearly seen in the recombinant PrPs expressed from E.coli after treatment of H2O2.MTT and trypan blue staining assays revealed that the cells expressing the mutated PrPs within octarepeats are less viable than the cells expressing wild-type PrP.Statistically significant high levels of intracellular free radicals and low levels of glutathione peroxidase were observed in the cells transfected with plasmids containing deleted or inserted octarepeats.Remarkably more productions of carbonyl groups were detected in the cells expressing PrPs with deleted and inserted octarepeats after exposing to H2O2.Furthermore,cells expressing wild-type PrP showed stronger resistant activity to the challenge of H2O2 at certain extent than the mutated PrPs and mock. These data provided the evidences that the octarepeats number within PrP is critical for maintaining its activity of antioxidation.Loss of its protective function against oxidative stress may be one of the possible pathways for the mutated PrPs to involve in the pathogenesis of familial Creutzfeldt-Jacob diseases. | AN Run1 ,2,DONG ChenFang 2,LEI YanJun 1,2,HAN Lu 2,LI Ping 2,CHEN JianMing 2,WANG GuiRong 2, SHI Qi 2 ,GAO Chen 2 ,JIANG HuiYing 2 ,ZHOU Wei 2 ,HAN Jun 2 ,CHU YongLie 1 ,DONG XiaoPing 2 1School of Medicine,Xi’an JiaoTong University,Xi’an 710061,China 2State Key Laboratory for Infectious Disease Prevention and Control,National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention,YingXin Rd 100,Beijing 100052,China | 2008 | Science China(Life Sciences)2008，51，7： | 3 |
| 8 | Effects of processing parameters and addition of flame-retardant into moulding sand on the microstructure and fluidity of sand-cast magnesium alloy Mg-10Gd-3Y-0.5Zr显示文摘In this study, the effects of processing parameters(such as pouring temperature and mould pre-heating temperature) and flame-retardant content on the microstructure and fluidity of sand-cast magnesium(Mg) alloy Mg-10Gd-3Y-0.5Zr(GW103K) were systematically investigated. It was found that the increase of pouring temperature leads to coarsened microstructure and decreased fluidity of sand-cast GW103 K alloy. Increase of mould pre-heating temperature incurs coarsening of as-cast microstructure and increase of fluidity. The addition of flame-retardant into moulding sand has a negligible influence on the microstructure of sand-cast GW103 K alloy. With the increase in flame-retardant content,fluidity of the alloy initially increases and then decreases. The optimized process parameters and flameretardant addition were obtained to be pouring temperature of 750?C, mould temperature of 110?C, and flame-retardant addition of 1%. The fire retardant mechanism of moulding sand was determined. | Yanlei Li Guohua Wu Antao Chen Wencai Liu Yingxin Wang Liang Zhang | 2017 | Journal of Materials Science & Technology2017，33，6： | 2 |
| 9 | Optimization of an in vitro method to measure the bioaccessibility of polybrominated diphenyl ethers in dust using response surface methodology显示文摘To more reasonably evaluate human intake of PBDEs via dust ingestion,bioaccessibility should be taken into account.Previously,we developed an in vitro method to determine the bioaccessibility of PBDEs in food.Here,this method was adapted to determine the bioaccessibility of PBDEs in dust and the digestion conditions that influenced the bioaccessibility of PBDEs were optimized.The digestion conditions included the incubation time of dust in the intestinal digestion solution (T),the bile concentration in the intestinal digestion solution (C bile),and the ratio of the volume of the intestinal digestion solution to dust (R).The influence of the concentrations of individual PBDE congeners (C PBDE) on the bioaccessibility of PBDEs was also investigated.Central composite design was used to build an experimental model and set experimental parameters,and response surface methodology was used to analyze the obtained data.The results showed that the bioaccessibility of PBDEs increased with the increases of C bile and R,and was independent of T and C PBDE.Under the digestion conditions with C bile and R being at 4.0-7.0 g/L and 150-250,respectively,the bioaccessibility of PBDEs in the method-dust varied from 39.2% to 72.8%,which were comparable with the bioaccessibility or bioavailability of PBDEs in dust/soil in the literature.Thus,the in vitro method to measure the bioaccessibility of PBDEs in dust was established and validated.Finally,the bioaccessibility of PBDEs in four natural dust samples,which ranged from 36.1% to 43.3%,were determined using the adapted method. | Yingxin Yu Yuping Pang Xinyu Zhang Chen Li Zhiqiang Yu Jiamo Fu | 2011 | Journal of Environmental Sciences2011，23，10： | 2 |
| 10 | Trace elements in fish from Taihu Lake, China: Levels, associated risks, and trophic transfer显示文摘 | Ying Hao Liang Chen Xiaolan Zhang Dongping Zhang Xinyu Zhang Yingxin Yu Jiamo Fu | 2013 | Ecotoxicology and Environmental Safety2013，，： | 1 |
| 11 | Diversity and seasonal variation of marine phytoplankton in Jiaozhou Bay, China revealed by morphological observation and metabarcoding显示文摘Phytoplankton are central components of marine environments,and are major players in the production and respiration budgeting.However,their diversity and distribution patterns are still poorly understood due largely to their small sizes and inconspicuous morphology that have been determined via the application of traditional morphology methods over the past two decades.To better understand the composition and diversity of phytoplankton in Jiaozhou Bay,China,seasonal sampling was carried out in 2019 and samples were analyzed with morphological observations and high-throughput sequencing,from which obvious seasonal variations in phytoplankton composition and proportional abundances were uncovered.Metabarcoding revealed far more diversity and species richness of phytoplankton than morphological observations,especially with respect to dinofl agellates.Diatoms were the most dominant phytoplankton group throughout the year,of which Thalassionema and Skeletonema were co-dominant in the bay.Parasitic dinofl agellates(e.g.Amoebophrya),which is often overlooked in the morphological observations,were in dominance and high diversity in the metabarcoding dataset,thus more attention should be paid to exploring the potential role of parasitic dinofl agellates.Temperature,chlorophyll a,and nutrient levels were the main infl uential factors on the distribution of phytoplankton.This study provided a comprehensive morphological and molecular description of phytoplankton and clearly demonstrated the importance of molecular technology in exploring phytoplankton communities.More-widespread use of molecular technology will facilitate deeper understanding of the ecological importance of the diff erent species. | Tiantian CHEN Yingxin ZHANG Shuqun SONG Yun LIU Xiaoxia SUN Caiwen LI | 2022 | Journal of Oceanology and Limnology2022，40，2： | 1 |
| 12 | microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells显示文摘 | Lin Liu Lin Chen Yingxin Xu Rong Li Xiaohui Du | 2010 | Biochemical and Biophysical Research Communications2010，，2： | 1 |
| 13 | Feasibility assessment of up-flow anaerobic sludge blanket treatment of sulfamethoxazole pharmaceutical wastewater显示文摘Treatment of sulfamethoxazole pharmaceutical wastewater is a big challenge.In this study,a series of anaerobic evaluation tests on pharmaceutical wastewater from different operating units was conducted to evaluate the feasibility of using anaerobic digestion,and the results indicated that the key refractory factor for anaerobic treatment of this wastewater was the high sulfate concentration.A laboratory-scale up-flow anaerobic sludge blanket(UASB)reactor was operated for 195 days to investigate the effects of the influent chemical oxygen demand(COD),organic loading rate(OLR),and COD/SO_(4)^(2-) ratio on the biodegradation of sulfamethoxazole in pharmaceutical wastewater and the process performance.The electron flow indicated that methanogenesis was still the dominant reaction although sulfidogenesis was enhanced with a stepwise decrease in the influent COD/SO_(4)^(2-) ratio.For the treated sulfamethoxazole pharmaceutical wastewater,a COD of 4983 mg/L(diluted by 50%),OLR of 2.5 kg COD/(m^(3)·d),and COD/SO_(4)^(2-) ratio of more than 5 were suitable for practical applications.The recovery performance indicated that the system could resume operation quickly even if production was halted for a few days. | Yi Chen Shilong He Mengmeng Zhou Tingting Pan Yujia Xu Yingxin Gao Hengkang Wang | 2018 | Frontiers of Environmental Science & Engineering2018，12，5： | 1 |
| 14 | Enhanced chemical trapping and catalytic conversion of polysulfides by diatomite/MXene hybrid interlayer for stable Li-S batteries显示文摘Lithium-Sulfur (Li-S) batteries with high theoretical energy density are promising energy storage systems in the next decades, while the lithium polysulfides (LiPSs) shuttling caused by the sluggish sulfur redox reaction severely lowers the practical performance. The use of interlayer between the cathode and separator has been widely investigated to physically or chemically block the LiPSs, while the introduction of catalytic materials is a more effective strategy to accelerate the conversion of LiPSs. MXene with rich surface chemistry has shown its potential for facilitating the catalytic conversion, however, the aggregation of MXene sheets usually leads to the loss of the catalytic active sites. Herein, we report a diatomite/MXene (DE/MX) hybrid material as the bifunctional interlayer for improving the adsorption/conversion of LiPSs in Li-S batteries. The diatomite with porous structure and rich silica-hydroxyl functional groups could trap LiPSs effectively, while prevent the aggregation of MXene. The DE/MX based interlayer showed bifunctions of enhancing the chemical adsorption and promoting the conversion of LiPSs. The Li-S batteries with the DE/MX interlayer delivered an improved cycling stability with a low capacity decay of 0.059% per cycle over 1000 cycles at 1.0 C. Moreover, stable 200 cycles can be realized with a high sulfur loading electrode up to 6.0 mg cm^(−2). This work provides an effective strategy to construct bifunctional interlayers for hindering the shuttling of LiPSs and boosting the practical application of Li-S batteries. | Zehui Fan Chen Zhang Wuxing Hua Huan Li Yan Jiao Jingyi Xia Chuan-Nan Geng Rongwei Meng Yingxin Liu Quanjun Tang Ziyang Lu Tongxin Shang Guowei Ling Quan-Hong Yang | 2021 | Journal of Energy Chemistry2021，30，11： | 1 |
| 15 | Mechanistic insights into the selective hydrogenation of resorcinol to 1,3-cyclohexanedione over Pd/rGO catalyst through DFT calculation显示文摘In our previous work, graphene-supported Pd catalyst(Pd/rGO) exhibited higher activity and selectivity for the liquid phase selective hydrogenation of resorcinol to 1,3-cyclohexanedione compared with other catalysts. In the present study, further experimental and theoretical investigations were conducted to reveal the reaction mechanism and the catalytic mechanism of Pd/rGO for resorcinol hydrogenation. The effects of graphene nanosheet and the solvent on the reaction were investigated, and the pathway for resorcinol hydrogenation was proposed supported by density functional theory(DFT) calculations. The results showed that the excellent selectivity of Pd/rGO to 1,3-cyclohexanedione was attributed to the strong π–π and p–π interactions between the graphene nanosheet and the benzene ring as well as hydroxyl in resorcinol molecule, which was in agreement with our previous speculation. In weak polar aprotic solvents, solvation free energy had less impact to the π–π and p–π interactions mentioned above. In strong polar aprotic solvents and polar protic solvents,however, the influence of solvation free energy was much greater, which led to the decrease in the conversion of resorcinol and the selectivity to 1,3-cyclohexanedione. | Zuojun Wei Haiyan Liu Yidong Chen Dechao Guo Ruofei Pan Yingxin Liu | 2018 | Chinese Journal of Chemical Engineering2018，26，12： | 1 |
| 16 | The Effect of 17-Methoxyl-7-Hydroxy-Benzene-Furanchalcone on NF-κB and the Inflammatory Response During Myocardial Ischemia Reperfusion Injury in Rats显示文摘 | Xingmei Liang Jianchun Huang Xing Lin Feizhang Qin Qingwei Wen Chunxia Chen Yingxin Li Wenyi Ge Renbin Huang | 2014 | Journal of Cardiovascular Pharmacology2014，，1： | 1 |
| 17 | microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells显示文摘 | Lin Liu Lin Chen Yingxin Xu Rong Li Xiaohui Du | 2010 | Biochemical and Biophysical Research Communications2010，，2： | 1 |
| 18 | Direct sequencing and amplification refractory mutation system for epidermalgrowth factor receptor mutations in patients with non-small cell lung cancer显示文摘 | Huili Chu Chen Zhong Guoliang Xue Xiuju Liang Jun Wang Yingxin Liu Shiwei Zhao Qian Zhou Jingwang Bi | 2013 | Oncology Reports2013，，5： | 1 |
| 19 | Influence of imidazole derivatives on the dielectric and energy storage performance of epoxy显示文摘Imidazoles are widely used as curing agents and accelerators for fabricating crosslinked epoxy materials applied in electrical and electronic fields.However,the intrinsic chemical structure of imidazole derivatives would greatly influence the polymerisation process,and further change the electrical properties,which was not emphasised.To achieve an in-depth understanding,commonly used imidazole only containing pyridine-type nitrogen and imidazole with both pyridine and pyrrole-type nitrogen were selected in this study.Electrical properties including dielectric properties,volume resistivity,breakdown strength,and especially energy storage performances were systematically investigated.We figured out that higher breakdown strength,glass transition temperature,and lower dielectric loss can be achieved with imidazole containing pyrrole-type nitrogen.Structure-induced curing mechanism diversity and the generated differences in polymer network were highlighted.With the capability to incorporate into the polymer network,the dielectric constant/loss of epoxy cured by imidazole containing pyrrole-type nitrogen is less sensitive with variation in concentration and a high breakdown strength of 577.9 MV/m was achieved.On the contrary,conspicuous decrease in the breakdown strength and increase in dielectric loss of the epoxy cured by imidazole only containing pyridine-type nitrogen were observed,especially at high concentration.Moreover,we also found that the epoxy can be fabricated into films with an attractive energy storage density/efficiency of 1.1 J/cm^(3)/97%@200 MV/m,which is twice of the commercial dielectric polypropylene film under the same electric field. | Jiaming Luo Lei Zhang Wenjie Sun Jiale Mao Yiting Zheng Shuang Wang Ziqi Zhang Yingxin Chen Yonghong Cheng | 2022 | High Voltage2022，7，4： | 1 |
| 20 | Effective adsorption of Cr (VI) from aqueous solution using natural Akadama clay显示文摘 | Yingxin Zhao Shengjiong Yang Dahu Ding Jie Chen Yingnan Yang Zhongfang Lei Chuanping Feng Zhenya Zhang | 2013 | Journal of Colloid And Interface Science2013，，： | 1 |
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