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| 1 | Impacts of soil organic matter, pH and exogenous copper on sorption behavior of norfloxacin in three soils显示文摘Norfloxacin sorption and the factors (soil organic matter (SOM), pH, and exogenous copper (Cu) inffluencing the sorption were investigated in a black soil (soil B), a ?uvo-aquic soil (soil F), and a red soil (soil R). With increasing norfloxacin concentrations, sorption amount of norfloxacin increased in both the bulk soils and their SOM-removed soils, but the sorption capacity of SOM-removed soils was higher than that of their corresponding bulk soils, indicating that the process of norfloxacin sorption in soil was influenced by the soil properties including SOM. The sorption data in all bulk soils and SOM-removed soils were fitted to Freundlich and Langmuir models. The correlation coeflcients suggested that the experimental data fitted better to Freundlich equation than to Langmuir equation. Furthermore, the data from soil F and SOM-removed F could not be described by Langmuir equation. The norfloxacin sorption amount decreased in soil B and soil F, whereas it increased in soil R as solution pH increased. The maximum KD and KOC were achieved in soil R when the equilibrium solution pH was 6. The norfloxacin sorption was also influenced by the exogenous Cu2+, which depended on the soil types and Cu2+ concentrations. With increasing Cu2+ concentrations in solution, generally, sorption amount, KD and KOC for norfloxacin in soils increased and were up to a peak at 100 mg/L Cu2+, and then the sorption amount decreased regardless of norfloxacin levels. | ZHANG Jie LI Zhaojun GE Gaofei SUN Wanchun LIANG Yongchao WU Laosheng | 2009 | Journal of Environmental Sciences2009，21，5： | 21 |
| 2 | Experimental Research on Gas-Liquid Two-Phase Spiral Flow in Horizontal Pipe显示文摘In view of the importance of gas-liquid two-phase spiral flow and the few research reports at home and abroad,the gas-liquid two-phase spiral flow patterns have been researched in a horizontal pipe with different parameters investigated by means of observation and a high-speed camera.Since the appearance of spiral flow makes the distribution of twophase flow more complicated,the flow patterns appearing in the experiments were divided into the Spiral Wavy Stratified Flow(SWS),the Spiral Bubble Flow(SB),the Spiral Slug Flow(SS),the Spiral Linear Flow(SL),the Spiral Axial Flow(SA),and the Spiral Dispersed Flow(SD) by the observations and with reference to the predecessors' research achievements.A flow pattern map has been drawn up.The influence of velocity,vane angle and vane area on flow pattern conversion boundary and pressure drop has been studied,with a solid foundation laid for the future research work. | Wang Shuli Rao Yongchao Wu Yuxian Wang Xiaobing | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，3： | 7 |
| 3 | m6A demethylase FTO attenuates cardiac dysfunction by regulating glucose uptake and glycolysis in mice with pressure overload-induced heart failure显示文摘Dear Editor,N6-methyladenosine(m6A)is the most common posttranscriptional mammalian mRNA modification involved in multiple biological processes and diseases.1 However,its role in cardiac energy metabolism changes during heart failure(HF)remains elusive.Here we explored the role of m6A demethylase fat mass and obesity-associated protein(FTO)in glucose metabolism during pressure overload-induced HF.Methylated RNA immunoprecipitation sequencing(MeRIP-seq)was performed to map transcriptome-wide m6A modifications in transverse aortic constriction(TAC)and sham hearts.The number of identified m6A peaks was higher in the TAC than in the sham hearts(Fig.1a).Consistent with previous reports,the m6A peaks were enriched in 3’-untranslated regions in both the TAC and sham hearts(Fig.1b).2 The m6A peaks were characterized by the canonical RGAAR(R=A or G)motif(Fig.1c). | Beijian Zhang Hao Jiang Jian Wu Yun Cai Zhen Dong Yongchao Zhao Qinfeng Hu Kai Hu Aijun Sun Junbo Ge | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 6 |
| 4 | Kindlin-2 inhibits Nlrp3 inflammasome activation in nucleus pulposus to maintain homeostasis of the intervertebral disc显示文摘Intervertebral disc(IVD) degeneration(IVDD) is the main cause of low back pain with major social and economic burdens;however, its underlying molecular mechanisms remain poorly defined. Here we show that the focal adhesion protein Kindlin-2 is highly expressed in the nucleus pulposus(NP), but not in the anulus fibrosus and the cartilaginous endplates, in the IVD tissues. Expression of Kindlin-2 is drastically decreased in NP cells in aged mice and severe IVDD patients. Inducible deletion of Kindlin-2 in NP cells in adult mice causes spontaneous and striking IVDD-like phenotypes in lumbar IVDs and largely accelerates progression of coccygeal IVDD in the presence of abnormal mechanical stress. Kindlin-2 loss activates Nlrp3 inflammasome and stimulates expression of IL-1β in NP cells, which in turn downregulates Kindlin-2. This vicious cycle promotes extracellular matrix(ECM) catabolism and NP cell apoptosis. Furthermore, abnormal mechanical stress reduces expression of Kindlin-2, which exacerbates Nlrp3 inflammasome activation, cell apoptosis, and ECM catabolism in NP cells caused by Kindlin-2 deficiency. In vivo blocking Nlrp3 inflammasome activation prevents IVDD progression induced by Kindlin-2 loss and abnormal mechanical stress. Of translational significance, adeno-associated virus-mediated overexpression of Kindlin-2 inhibits ECM catabolism and cell apoptosis in primary human NP cells in vitro and alleviates coccygeal IVDD progression caused by mechanical stress in rat. Collectively, we establish critical roles of Kindlin-2 in inhibiting Nlrp3 inflammasome activation and maintaining integrity of the IVD homeostasis and define a novel target for the prevention and treatment of IVDD. | Sheng Chen Xiaohao Wu Yumei Lai Di Chen Xiaochun Bai Sheng Liu Yongchao Wu Mingjue Chen Yuxiao Lai Huiling Cao Zengwu Shao Guozhi Xiao | 2022 | Bone Research2022，10，1： | 6 |
| 5 | Tertiary Sea Level Changes and Sequence Stratigraphic Framework in East China Sea Shelf Basin显示文摘TheEastChinaSeashelfbasinissituatedonthewestmarginofPacificplate(Fig.1)andisalargehydrocarbon-bearingsedimentarybasinfiledmai... | Wu Fadong Li Sitian Lu Yongchao Department of Geology and Mineral Resources, China University of Geosciences, Beijing 100083 Zhou Ping Li Peilian Liu Jinshui Shanghai Marine Petroleum Survey, Shanghai 200120 | 1999 | Journal of Earth Science1999，18，2： | 3 |
| 6 | Culture of nucleus pulposus cells from intervertebral disc on self-as- sembling KLD-12 peptide hydrogel scaffold显示文摘 | Sun Jianhua Zheng Qixin Wu Yongchao | 2010 | Mater Sci Eng C2010，30，： | 1 |
| 7 | Effects of salinity and nitrogen on cotton growth in arid environment显示文摘 | Weiping Chen Zhenan Hou Laosheng Wu Yongchao Liang Changzhou Wei | 2010 | Plant and Soil . 2010 (1-2)2010，，1： | 1 |
| 8 | A core-satellite structured type Ⅱ heterojunction photocatalyst with enhanced CO_(2) reduction under visible light显示文摘Photocatalytic reduction of carbon dioxide into valuable chemicals is a sustainable and promising technology that alleviates the greenhouse effect and energy crisis.In this study,the Mn_(3)O_(4)/FeNbO_(4) type Ⅱ heterojunction photocatalyst with a core-satellite structure was synthesized by the facile soft chemical method.The formation of a nano-heterojunction is supposed to effectively improve light capture,charge transfer,and interfacial charge separation in the photochemical reaction.Meanwhile,the heterojunction has a good ability to capture and activate CO_(2).Our results show that the prepared Mn_(3)O_(4)/FeNbO_(4) photocatalyst exhibit obvious enhanced catalytic properties in the photocatalytic CO_(2) reduction reaction,where the CH_(4) yielding rate is 1.96 and 9.81 times those of FeNbO_(4) and Mn_(3)O_(4),respectively.The transient photovoltage test(TPV)shows that the low frequency electrons are crucial to the effective transfer of photogenerated electrons and holes in the Mn_(3)O_(4)/FeNbO_(4) nano heterojunctions.Analysis of in situ Fourier transform infrared spectroscopy(FTIR)verifies the effective CO_(2) adsorption on the Mn_(3)O_(4)/FeNbO_(4) surface and the high selectivity of CH_(4) products.These properties of the Mn_(3)O_(4)/FeNbO_(4) photocatalyst infer its broad prospects in the fields of carbon fixation and energy conservation. | Yuanyuan Cheng Yixian Liu Yunliang Liu Yaxi Li Ruqiang Wu Yongchao Du Najmeh Askari Naiyun Liu Fen Qiao Chenghua Sun Zhenhui Kang Haitao Li | 2022 | Nano Research2022，15，10： | 1 |
| 9 | Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer显示文摘 | Jing Zhao Yongchao Liu Wenhong Zhang Zhongwen Zhou Jing Wu Peng Cui Ying Zhang Guangjian Huang | 2015 | Cell Cycle2015，，19： | 1 |
| 10 | Culture of nucleus pulposus cells from intervertebral disc on self-assembling KLD-12 peptide hydrogel scaffold显示文摘 | Sun Jianhua Zheng Qixin Wu Yongchao | | 0，，： | 1 |
| 11 | Depositional Responding to Tectonic Evolution of East China Sea Shelf Basin显示文摘DepositionalRespondingtoTectonicEvolutionofEastChinaSeaShelfBasin*LuYongchaoWuFadongXieXinongChenPingFacultyofEarthResources,... | Lu Yongchao Wu Fadong Xie Xinong Chen PingFaculty of Earth Resources, China University of Geosciences, Wuhan 430074 Zhou Ping Li Peilian Xu WeilingShanghai Institute of Offshore Petroleum Exploration and Development, MGMR, Shanghai 200120 | 1997 | Journal of Earth Science1997，16，1： | 1 |
| 12 | Growth of rat dorsal root ganglion neurons on a novel self-assembling scaffold containing IKVAV sequence显示文摘 | Zou Zhenwei Zheng Qixin Wu Yongchao | 2009 | Mater Sci Eng C2009，29，： | 1 |
| 13 | Influence of alloy elements on microstructure and mechanical property of aluminum - steel lap joint made by gas metal arc welding显示文摘 | Su Yongchao Hua Xueming and Wu Yixiong | 2014 | Journal of Materi- als Processing Technology2014，214，4： | 1 |
| 14 | Culture of nucleus pulposus cells from intervertebral disc on self-assembling KLD-12 peptide hydrogel scaffold显示文摘 | Jianhua Sun Qixin Zheng Yongchao Wu Yudong Liu Xiaodong Guo Weigang Wu | 2010 | Materials Science & Engineering C2010，，7： | 1 |
| 15 | Boosted Storage Kinetics in Thick Hierarchical Micro-Nano Carbon Architectures for High Areal Capacity Li-Ion Batteries显示文摘A practical and effective approach to increase the energy storage capacity of lithium ion batteries(LIBs)is to boost their areal capacity.Developing thick electrodes is one of the most crucial ways to achieve high areal capacity but limited by sluggish ion/electron transport,poor mechanical stability,and high-cost manufacturing strategies.Here we address these constraints by engineering a unique hierarchical-networked 10 mm thick all-carbon electrode,providing a scalable strategy to produce high areal capacity LIB electrodes.The hierarchical-networked structure utilizes micrometer-sized carbon fibers(MCFs)as building blocks,nano-sized carbon nanotubes(CNTs)as good continuous network with excellent electrical conductivity,and pyrolytic carbon as the binder and active material with excellent storage capacity.The combination of the above features endows our HNT-MCF/CNT/PC electrode with excellent performance including high reversible capacity of 15.44 mAh cm^(-2) at 2.0 mA cm^(-2) and exhibits excellent rate capability of 2.50 mAh cm^(-2) under 10.0 mA cm^(-2) current density.The Li-ion storage mechanism in HNT-MCF/CNT/PC involves dual-storage mechanism including intercalation and surface adsorption(pseudocapacitance)confirmed by the cyclic voltammetry and symmetric cell analysis.This work provides insights into the construction of high mechanical stability thick electrode for the next generation high areal capacity LIBs and beyond. | Yang Wu Ting Ouyang Tuzhi Xiong Zhao Jiang Yuwen Hu Jianqiu Deng Zhongmin Wang Yongchao Huang M.-Sadeeq(Jie Tang)Balogun | 2022 | Energy & Environmental Materials2022，5，4： | 0 |
| 16 | Endoscopic ultrasound-guided injection of carbon nanoparticles suspension to label rectal cancer before neoadjuvant chemoradiotherapy:a retrospective cohort study显示文摘Background:Localization of the primary tumor and ensuring safe distal surgical margins(DSMs)following neoadjuvant chemoradiotherapy(nCRT)are challenging in locally advanced rectal cancers(LARCs).This study investigated the effectiveness of carbon nanoparticles suspension(CNS)for labeling the primary tumor and allowing precise tumor resection after nCRT.Methods:Clinicopathological data of LARC patients who underwent nCRT followed by laparoscopic radical anal preservation surgery at our center between January 2018 and February 2023 were prospectively collected.The patients were divided into the CNS tattooed(CNS)and non-tattooed(control)groups.In the CNS group,CNS was injected in four quadrants on the anal side 1 cm away from the lower tumor margin.DSMs were determined through intraoperative distal rectal examination in the control group and observation of CNS tattoos in the CNS group.DSM lengths and positive DSM rates were compared between the two groups to analyse the feasibility and effectiveness of CNS for labeling LARCs before nCRT.Results:There was no statistically significant difference in the basic demographic data,effectiveness of nCRT,or post-operative recovery rates between the two groups(all P>0.05).In the CNS group,CNS tattoos were observed on the outside of the rectal wall,with an overall efficiency of 87.1%(27/31).The CNS group had fewer positive DSMs and safer DSM lengths(2.73±0.88 vs 2.12±1.15 cm,P=0.012)than the control group(P<0.05).Conclusions:Endoscopic ultrasound-guided injection of CNS tattoos before nCRT could effectively label the LARCs,ensuring safe DSMs during anus-preserving surgeries(Chictr.org.cn No.:ChiCTR2300068991). | Nan Lin Yuanzhao Wang Changwei Yu Weihang Wu Yongchao Fang Jin Yang Wangwu Liu Rong Wang Yanyan Jiang Yu Wang | 2023 | Gastroenterology Report2023，11，1： | 0 |
| 17 | Recent developments of anti-plasticized membranes for aggressive CO_(2)separation显示文摘Membrane separation technology provides an effective alternative to mitigate the massive carbon emission with high carbon capture productivity and efficiency.In the context of operating membranes under high CO_(2)pressures allows increased separation productivity and reduced gas compression cost,which,however,often leads to CO_(2)induced plasticization,a key hurdle for current gas separation membranes.In this review,we reviewed the latest development of membranes with anti-plasticization resistance,potentially suited for operation under high CO_(2)feed streams.Specifically,the separation performance of polymeric membranes,inorganic membranes,and mixed matrix membranes under high CO_(2)feed pressures are discussed.Approaches to enhance CO_(2)induced plasticization of those membranes are also summarized.We conclude the recent progress of membranes for high CO_(2)pressures with perspectives and an outlook for future development. | Yongchao Sun Xiaoyu Wang Xiangcun Li Wu Xiao Yan Dai Canghai Ma Gaohong He | 2023 | Green Chemical Engineering2023，4，1： | 0 |
| 18 | A review of interaction mechanisms and microscopic simulation methods for CO_(2)-water-rock system显示文摘This work systematically reviews the complex mechanisms of CO_(2)-water-rock interactions,microscopic simulations of reactive transport(dissolution,precipitation and precipitate migration)in porous media,and microscopic simulations of CO_(2)-water-rock system.The work points out the key issues in current research and provides suggestions for future research.After injection of CO_(2) into underground reservoirs,not only conventional pressure-driven flow and mass transfer processes occur,but also special physicochemical phenomena like dissolution,precipitation,and precipitate migration.The coupling of these processes causes complex changes in permeability and porosity parameters of the porous media.Pore-scale microscopic flow simulations can provide detailed information within the three-dimensional pore and throat space and explicitly observe changes in the fluid-solid interfaces of porous media during reactions.At present,the research has limitations in the decoupling of complex mechanisms,characterization of differential multi-mineral reactions,precipitation generation mechanisms and characterization(crystal nucleation and mineral detachment),simulation methods for precipitation-fluid interaction,and coupling mechanisms of multiple physicochemical processes.In future studies,it is essential to innovate experimental methods to decouple“dissolution-precipitation-precipitate migration”processes,improve the accuracy of experimental testing of minerals geochemical reaction-related parameters,build reliable characterization of various precipitation types,establish precipitation-fluid interaction simulation methods,coordinate the boundary conditions of different physicochemical processes,and,finally,achieve coupled flow simulation of“dissolution-precipitation-precipitate migration”within CO_(2)-water-rock systems. | ZHANG Liehui ZHANG Tao ZHAO Yulong HU Haoran WEN Shaomu WU Jianfa CAO Cheng WANG Yongchao FAN Yunting | 2024 | Petroleum Exploration and Development2024，51，1： | 0 |
| 19 | Selenium nanoparticles derived from Proteus mirabilis YC801 alleviate oxidative stress and inflammatory response to promote nerve repair in rats with spinal cord injury显示文摘Microbial biotransformation and detoxification of biotoxic selenite into selenium nanoparticles(SeNPs)has emerged as an efficient technique for the utilization of selenium.SeNPs are characterized by high bioavailability and have several therapeutic effects owing to their antioxidant,anti-inflammatory and neuroprotective activities.However,their influence onmicroenvironment disturbances and neuroprotection after spinal cord injury(SCI)is yet to be elucidated.This study aimed to assess the influence of SeNPs on SCI and explore the underlying protective mechanisms.Overall,the proliferation and differentiation of neural stem cells were facilitated by SeNPs derived from Proteus mirabilis YC801 via the Wnt/b-catenin signaling pathway.The SeNPs increased the number of neurons to a greater extent than astrocytes after differentiation and improved nerve regeneration.A therapeutic dose of SeNPs remarkably protected the integrity of the spinal cord to improve the motor function of the hind limbs after SCI and decreased the expression of several inflammatory factors such as tumor necrosis factor-a and interleukin-6 in vivo and enhanced the production of M2-type macrophages by regulating their polarization,indicating the suppressed inflammatory response.Besides,SeNPs reversed the SCI-mediated production of reactive oxygen species.In conclusion,SeNPs treatment holds the potential to improve the disturbed microenvironment and promote nerve regeneration,representing a promising therapeutic approach for SCI. | Xiangyu Liu Yingji Mao Shengwei Huang Weifeng Li Wei Zhang Jingzhou An Yongchao Jin Jianzhong Guan Lifang Wu Pinghui Zhou | 2022 | Regenerative Biomaterials2022，9，1： | 0 |
| 20 | THROUGHPUT ANALYSIS OF TWO-HOP WIRELESS NETWORKS WITH NETWORK CODING显示文摘A Two-hop Wireless Network (TWN) is the basic topology structure that provides network coding opportunity for improving throughput. Network coding on a homogeneous TWN, in which all the data flows have the same packet size and all the links have the same transmission rate, has been extensively investigated. In this paper, network coding on more practical heterogeneous TWNs, featured by various packet sizes and transmission rates, is studied. Based on the Markov model, the throughput of the proposed network coding scheme, together with the throughput gain, is derived, which matches the simulation results very well. Numerical analyses indicate that, encoding the packets with close size and close transmission rate and enlarging buffer size at the relay node help in improving the throughput gain. | Wu Yongchao Chi Kaikai Zhu Yihua | 2013 | Journal of Electronics(China)2013，30，2： | 0 |
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