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| 1 | Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update of clinical management of ischaemic cerebrovascular diseases显示文摘Aim Stroke is the leading cause of disability and death in China.Ischaemic stroke accounts for about 60%-80%of all strokes.It is of considerable significance to carry out multidimensional management of ischaemic cerebrovascular diseases.This evidence-based guideline aims to provide the latest detailed and comprehensive recommendations on the diagnosis,treatment and secondary prevention of ischaemic cerebrovascular diseases.Methods We had performed comprehensive searches of MEDLINE(via PubMed)(before 30 June 2019),and integrated the relevant information into charts and distributed to the writing group.Writing group members discussed and determined the recommendations through teleconference.We used the level of evidence grading algorithm of Chinese Stroke Association to grade each recommendation.The draft was reviewed by the Guideline Writing Committee of Chinese Stroke Association Stroke and finalised.This guideline is fully updated every 3 years.results This evidence-based guideline is based on the treatment,care and prevention of ischaemic cerebrovascular diseases,which emphasises on pathogenesis evaluation,intravenous thrombolysis,endovascular therapy,antiplatelet therapy,prevention and treatment of complications,and risk factor management.Conclusions This updated guideline presents a framework for the management of ischaemic cerebrovascular diseases.Timely first-aid measures,professional care in the acute stage,and proactive secondary prevention will be helpful to patients. | Liping Liu Weiqi Chen Hongyu Zhou Wanying Duan Shujuan Li Xiaochuan Huo Weihai Xu Li'an Huang Huaguang Zheng Jingyi Liu Hui Liu Yufei Wei Jie Xu Yongjun Wang | 2020 | Stroke & Vascular Neurology2020，5，2： | 42 |
| 2 | The CAMS Climate System Model and a Basic Evaluation of Its Climatology and Climate Variability Simulation显示文摘A new coupled climate system model(CSM) has been developed at the Chinese Academy of Meteorological Sciences(CAMS) by employing several state-of-the-art component models. The coupled CAMS-CSM consists of the modified atmospheric model [ECmwf-HAMburg(ECHAM5)], ocean model [Modular Ocean Model(MOM4)], sea ice model [Sea Ice Simulator(SIS)], and land surface model [Common Land Model(CoLM)]. A detailed model description is presented and both the pre-industrial and 'historical' simulations are preliminarily evaluated in this study.The model can reproduce the climatological mean states and seasonal cycles of the major climate system quantities,including the sea surface temperature, precipitation, sea ice extent, and the equatorial thermocline. The major climate variability modes are also reasonably captured by the CAMS-CSM, such as the Madden–Julian Oscillation(MJO), El Ni?o–Southern Oscillation(ENSO), East Asian Summer Monsoon(EASM), and Pacific Decadal Oscillation(PDO).The model shows a promising ability to simulate the EASM variability and the ENSO–EASM relationship. Some biases still exist, such as the false double-intertropical convergence zone(ITCZ) in the annual mean precipitation field,the overestimated ENSO amplitude, and the weakened Bjerknes feedback associated with ENSO; and thus the CAMS-CSM needs further improvements. | Xinyao RONG Jian LI Haoming CHEN Yufei XIN Jingzhi SU Lijuan HUA Tianjun ZHOU Yanjun QI Zhengqiu ZHANG Guo ZHANG Jianduo LI | 2018 | Journal of Meteorological Research2018，32，6： | 15 |
| 3 | COL4A3 mutations cause focal segmenta glomerulosclerosis显示文摘 | Jingyuan Xie Xiaoxi Wu Hong Ren Weiming Wang Zhaohui Wang Xiaoxia Pan Xu Hao Jun Tong Jun Ma Zhibin Ye Guoyu Meng Yufei Zhu Krzysztof Kiryluk Xiangyin Kong Landian Hu Nan Chen | 2014 | Journal of Molecular Cell Biology2014，8，6： | 15 |
| 4 | SIS accuracy and service performance of the BDS-3 basic system显示文摘On December 27,2018,the basic system of the third-generation BeiDou navigation satellite system(BDS-3)completed the deployment of its constellation of 18 MEO networking satellites as well as the construction of the operation control system(OCS)and began to provide basic navigation services to users worldwide.Compared with BDS-2,BDS-3 aims to offer users better navigation signals and higher precision with a series of new technologies.For example,the spaceborne atomic clock of BDS-3 is upgraded for higher performance,the Ka-band inter-satellite link is adopted for inter-satellite ranging and communication,and new B1C and B2a signals are broadcast in addition to B1I and B3I signals(compatible with BDS-2).In addition,a 9-parameter model based on a spherical harmonic function is employed for ionospheric delay corrections.Using the observation data from 18 satellites of the basic system,this paper conducts a comprehensive evaluation of the pseudorange measurement characteristics,signal-in-space(SIS)accuracy of navigation messages and global service capability of BDS-3.The results indicate that the pseudorange measurement multipath effect and observation noise of BDS-3 satellites are better than those of BDS-2;additionally,with the support of inter-satellite links,the user range error(URE)of the BDS-3 satellite broadcast ephemeris is better than 10 cm,the precision of the broadcast clock parameter is better than 1.5 ns,and the SIS accuracy is better than 0.6 m overall.Different from the traditional Klobuchar model,the BeiDou global broadcast ionospheric delay correction model(BDGIM)can provide ionospheric delay corrections better than 70%for worldwide single-frequency users.The service capability evaluation of the basic system consists mainly of the accuracy improvement of the B1I and B3I signals according to BDS-2 as well as the global positioning accuracy of the new signals.These results prove that the BDS-3 basic system has achieved the design goal;that is,both the horizontal and the vertical global positioning accuracies are better than 10 m(95%).In the future,6 MEO satellites as well as 3 GEO satellites and 3 IGSO satellites for regional enhancement purposes will be deployed for full operation;consequently,BDS-3 will definitely provide a higher SIS accuracy and better service capability. | JinPing Chen XiaoGong Hu ChengPan Tang ShanShi Zhou YuFei Yang JunYang Pan Hui Ren YueXin Ma QiuNing Tian Bin Wu Yang Yu | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，6： | 14 |
| 5 | Climate Sensitivity and Feedbacks of a New Coupled Model CAMS-CSM to Idealized CO_2 Forcing: A Comparison with CMIP5 Models显示文摘Climate sensitivity and feedbacks are basic and important metrics to a climate system. They determine how large surface air temperature will increase under CO_2 forcing ultimately, which is essential for carbon reduction policies to achieve a specific warming target. In this study, these metrics are analyzed in a climate system model newly developed by the Chinese Academy of Meteorological Sciences(CAMS-CSM) and compared with multi-model results from the Coupled Model Comparison Project phase 5(CMIP5). Based on two idealized CO_2 forcing scenarios, i.e.,abruptly quadrupled CO_2 and CO_2 increasing 1% per year, the equilibrium climate sensitivity(ECS) and transient climate response(TCR) in CAMS-CSM are estimated to be about 2.27 and 1.88 K, respectively. The ECS is near the lower bound of CMIP5 models whereas the TCR is closer to the multi-model ensemble mean(MME) of CMIP5 due to compensation of a relatively low ocean heat uptake(OHU) efficiency. The low ECS is caused by an unusually negative climate feedback in CAMS-CSM, which is attributed to cloud shortwave feedback(λSWCL) over the tropical Indo-Pacific Ocean.The CMIP5 ensemble shows that more negative λSWCL is related to larger increase in low-level(925–700 hPa)cloud over the tropical Indo-Pacific under warming, which can explain about 90% of λSWCL in CAMS-CSM. Static stability of planetary boundary layer in the pre-industrial simulation is a critical factor controlling the low-cloud response and λSWCL across the CMIP5 models and CAMS-CSM. Evidently, weak stability in CAMS-CSM favors lowcloud formation under warming due to increased low-level convergence and relative humidity, with the help of enhanced evaporation from the warming tropical Pacific. Consequently, cloud liquid water increases, amplifying cloud albedo, and eventually contributing to the unusually negative λSWCL and low ECS in CAMS-CSM. Moreover, the OHU may influence climate feedbacks and then the ECS by modulating regional sea surface temperature responses. | Xiaolong CHEN Zhun GUO Tianjun ZHOU Jian LI Xinyao RONG Yufei XIN Haoming CHEN Jingzhi SU | 2019 | Journal of Meteorological Research2019，33，1： | 11 |
| 6 | Drag prediction method of powered-on civil aircraft based on thrust drag bookkeeping显示文摘A drag prediction method based on thrust drag bookkeeping(TDB) is introduced for civil jet propulsion/airframe integration performance analysis.The method is derived from the control volume theory of a powered-on nacelle.Key problem of the TDB is identified to be accurate prediction of velocity coefficient of the powered-on nacelle.Accuracy of CFD solver is validated by test cases of the first AIAA Propulsion Aerodynamics Workshop.Then the TDB method is applied to thrust and drag decomposing of a realistic aircraft.A linear relation between the computations assumed free stream Mach number and the velocity coefficient result is revealed.The thrust losses caused by nozzle internal drag and pylon scrubbing are obtained by the isolated nacelle and mapped on to the in-flight whole configuration analysis.Effects of the powered-on condition are investigated by comparing through-flow configuration with powered-on configuration.The variance on aerodynamic coefficients and pressure distribution is numerically studied. | Zhang Yufei Chen Haixin Fu Song Zhang Miao Zhang Meihong | 2015 | Chinese Journal of Aeronautics2015，28，4： | 11 |
| 7 | Prediction of separation flows around a 6:1 prolate spheroid using RANS/LES hybrid approaches显示文摘这篇论文论述混合平均 Reynolds 的 Navier 司烧(RANS ) 并且为在在 6:1 附近的攻击的高角度的分开的流动的 large-eddy-simulation (LES ) 方法延长球状体。在这个工作学习的 RANS/LES 混合方法基于 Spalart Allmaras ( S A )包括分开的旋涡模拟( DES ), Menter 的 k ω
shear-stress-transport ( SST )和有弱非线性的旋涡粘性明确的表达的 k ω
(威尔科克斯Durbin+,WD+)模型和 zonal-RANS/LES 方法基于 SST 和WD+模型。从到在核心流动区域的 LES 的墙附近的 RANS 的开关通过为带的混合方法混合功能的一个流动依赖者的实现是光滑的。所有混合方法被设计为依附的流动有一个 RANS 模式并且为分开的流动有 LES 行为。这篇论文的主要目的是使用混合方法因为高级雷纳兹数字在延长球状体附近分开了流动在高发生。有第四顺序的人工的粘性的一个第四顺序的中央计划被申请空间 differencing。充分含蓄更低上面对称 -- 有假时间亚重复的高斯 Seidel 作为时间的区别被拿。有可得到的大小的比较为速度的压力分发,皮肤磨擦,和侧面被执行,等等。对实验的合理同意,为格子和基本骚乱上的效果的财务当模特儿,为分离流动被获得。 | Zhixiang Xiao Yufei Zhang Jingbo Huang Haixin Chen Song Fu School of Aerospace Engineering,Tsinghua University,Beijing 100084,China | 2007 | Acta Mechanica Sinica2007，23，4： | 10 |
| 8 | Branched tetraether lipids in Chinese soils:Evaluating the fidelity of MBT/CBT proxies as paleoenvironmental proxies显示文摘The ubiquitous occurrence of branched glycerol dialkyl glycerol tetraethers(br GDGTs) in soils has allowed development of new proxies for reconstruction of past climate and environment. The methylation and cyclization degrees of br GDGTs, expressed as MBT and CBT, respectively, are reported to be mainly controlled by mean annual air temperature(MAAT) and soil p H. However, the br GDGT-derived temperatures and soil p H scatter widely when data from different environmental conditions are considered. In this study, we collected over 300 soil samples from China, which are representative of humid(Xishuangbanna, Guangzhou, and Shanghai), semi-arid(Dongying) and semi-arid/arid(Lanzhou, Tibetan Plateau) regions. Collectively we have the most extensive dataset that broadly characterizes the distribution of br GDGTs according to climate zones in China. The overall data demonstrate that the MBT/CBT derived temperatures better match the measured MAATs in humid and non-alkaline regions than those from regions of low MAP(<400 mm/yr) and above neutral soil p H(>7.0–7.5). Similarly, CBT describes soil p H much better in humid and non-alkaline soils than in semi-arid/arid and alkaline soils; the semi-arid/arid and alkaline soils tend to show a positive correlation between soil p H and CBT, which contradicts that in the humid and non-alkaline soils. While soil p H, MAAT and mean annual precipitation(MAP) are dominating factors controlling the br GDGT distribution across all climate zones, conductivity, total organic carbon and total nitrogen, as well as soil water content can also play an important role locally. Removing br GDGT-II resulted in a revised CBT index that provides more accurate estimation of p H, especially in semi-arid/arid and alkaline soils. The overall Chinese dataset demonstrates that continental air temperature derived from br GDGT-proxies can vastly deviate from real measurements and should be used with extreme caution in paleo-climate or-environment studies. | ZHENG FengFeng ZHANG ChuanLun CHEN YuFei LI FuYan MA CenLing PU Yang ZHU YuanQing WANG YongLi LIU WeiGuo | 2016 | Science China Earth Sciences2016，59，7： | 10 |
| 9 | Recent advances of wearable and flexible piezoresistivity pressure sensor devices and its future prospects显示文摘The human skin inspired soft electronic devices have attracted broadly research attention in the past decades as the promising potential applications in health monitoring and diagnosis,robotics,and prosthetics.The soft wearable piezoresistivity pressure sensor is one of the most attractive candidates for the development of advanced electronic skin for its simple mechanism,compact structure,low cost and power energy consumption and ease of signal acquisition and transforms advantages.In this review,we will explore the recent progress and achievements in the field of piezoresistivity pressure sensor,focusing on the fundamentals of the piezoresistivity pressure sensor and the materials related to the devices,including active materials,substrate materials,and electrode materials.Subsequently,the challenges and outlook are discussed.We list several current challenges perspectives on the development of pressure sensors.Several critical topics for the optimization of the sensitivity and working range of sensing devices toward practical applications are discussed.Finally,perspectives on the slip and force vectors sensors,the developing technologies for multi-function and high-resolution sensor systems and signals process technologies are examined to highlight the near future development tendency in piezoresistivity pressure sensor research field. | Jiang He Yufei Zhang Runhui Zhou Lirong Meng Tao Chen Wenjie Mai Caofeng Pan | 2020 | Journal of Materiomics2020，6，1： | 9 |
| 10 | Analysis of complex intermittency in Boost converter from a bifurcation control viewpoint显示文摘Due to undesirable interference via unintended coupling paths, switching converters may exhibit complex intermittency, which appears as a form of bifurcation un-dergoing regular operation, subharmonics, and chaos orderly and repeatedly for a long period of time. Such intermittent operation, being an unwanted operating state, should normally be avoided in power converters. This paper expounds the mechanism and conditions for the emergence of intermittency in a common current-mode controlled Boost converter. It is found that interference at frequencies near the switching frequency or its rational multiples may induce intermittent operation. The strengths and frequencies of the interfering signals determine the type and period of intermittency. The problem is analyzed by transforming the time-bifurcation analysis to a conventional parameter-bifurcation analysis. Based on this transformation, intermittency can be investigated from the bifurcation control viewpoint. Furthermore, the critical circuit parameter conditions for the emergence of inter-mittency can be predicted and compared with those from circuit simulation. | ZHOU YuFei JIANG XueDong CHEN JunNing | 2008 | Science in China(Series F)2008，51，12： | 8 |
| 11 | Dynamic changes of CX3CL1/CX3CR1 axis during microglial activation and motor neuron loss in the spinal cord of ALS mouse model显示文摘Background:Neuron-microglia communication plays a crucial role in the motor neurons(MNs)death in amyotrophic lateral sclerosis(ALS).Neurons can express chemokine(C-X3-C motif)ligand 1(CX3CL1),which mediates microglial activation via interacting with its sole receptor CX3CR1 in microglia.In the present study,we aimed to investigate the dynamic changes of CX3CL1/CX3CR1 axis during microglial activation and MNs loss in SOD1G93A mouse model of ALS.Methods:qPCR,western blot and immunofluorescent staining were used to examine the mRNA and protein levels and localization of CX3CL1/CX3CR1 in the anterior horn region of spinal cord in both SOD1G93A mice and their agematched wild type(WT)littermates at 40,60,90 and 120 days of age.The M1/M2 microglial activation in the spinal cord tissues of SOD1G93A mice and WT mice were evaluated by immunofluorescent staining of M1/M2 markers and further confirmed by qPCR analysis of M1/M2-related cytokines.Results:The immunofluorescent staining revealed that CX3CL1 was predominately expressed in MNs,while CX3CR1 was highly expressed in microglia in the anterior horn region of spinal cord.Compared with age-matched WT mice,CX3CL1 mRNA level was elevated at 40 days but decreased at 90 and 120 days in the anterior horn region of spinal cords in ALS mice.Consistently,CX3CR1 mRNA level was increased at 90 and 120 days.Western blot assay further confirmed the dynamic changes of CX3CL1/CX3CR1 axis in ALS mice.Additionally,the levels of M1/M2 markers of microglia and their related cytokines in the anterior horn region of spinal cord in ALS mice were increased at 90 and 120 days.Moreover,while M1-related cytokines in ALS mice were persistently increased at 120 days,the upregulated M2-related cytokines started to decline at 120 days,suggesting an altered microglial activation.Conclusions:Our data revealed the dynamic changes of CX3CL1/CX3CR1 axis and an imbalanced M1/M2 microglial activation during ALS pathological progression.These findings may help identify potential molecular targets for ALS therapy. | Jingjing Zhang Yufei Liu Xinyao Liu Song Li Cheng Cheng Sheng Chen Weidong Le | 2018 | Translational Neurodegeneration2018，7，1： | 7 |
| 12 | Ultrasensitive and stable X-ray detection using zero-dimensional lead-free perovskites显示文摘Sensitive and reliable X-ray detectors are essential for medical radiography,industrial inspection and security screening.Lowering the radiation dose allows reduced health risks and increased frequency and fidelity of diagnostic technologies for earlier detection of disease and its recurrence.Three-dimensional(3 D)organic-inorganic hybrid lead halide perovskites are promising for direct X-ray detection-they show improved sensitivity compared to conventional X-ray detectors.However,their high and unstable dark current,caused by ion migration and high dark carrier concentration in the 3 D hybrid perovskites,limits their performance and long-term operation stability.Here we report ultrasensitive,stable X-ray detectors made using zero-dimensional(0 D)methylammonium bismuth iodide perovskite(MA3Bi2I9)single crystals.The 0 D crystal structure leads to a high activation energy(Ea)for ion migration(0.46 e V)and is also accompanied by a low dark carrier concentration(~10^6 cm^-3).The X-ray detectors exhibit sensitivity of 10,620μC Gy-1 air cm-2,a limit of detection(Lo D)of 0.62 nG yairs-1,and stable operation even under high applied biases;no deterioration in detection performance was observed following sensing of an integrated X-ray irradiation dose of^23,800 m Gyair,equivalent to>200,000 times the dose required for a single commercial X-ray chest radiograph.Regulating the ion migration channels and decreasing the dark carrier concentration in perovskites provide routes for stable and ultrasensitive X-ray detectors. | Xiaojia Zheng Wei Zhao Peng Wang Hairen Tan Makhsud I.Saidaminov Shujie Tie Ligao Chen Yufei Peng Jidong Long Wen-HuZhang | 2020 | Journal of Energy Chemistry2020，29，10： | 7 |
| 13 | A Karman-Vortex Generator for passive separation control in a conical diffuser显示文摘Flow separation in a conical diffuser with large divergence angle(29.14°) and large area ratio(3.533) is eliminated by a novel passive flow control device called Karman-Vortex Generator(KVG).The effect of the KVG is verified and investigated by the URANS,DES and DDES methods based on the SST model.CFD results show that the performance coefficient of the diffuser can be doubled by the KVG,and the total pressure recovery coefficient can be improved by about 1.2%.DES and DDES results show that the KVG can introduce a Karman-vortex street frequency in the diffuser.This frequency decays rapidly,and could not be detected in the ending plane of the expansion section.Different KVG configurations with different locations and dimensions are numerically simulated and compared.Some suggestions are provided. | ZHANG YuFei CHEN HaiXin FU Song | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，5： | 7 |
| 14 | Principle of designing slope compensation in PFC Boost converter显示文摘Due to wide input fluctuation with line frequency of 50 Hz, power-factor-correction (PFC) Boost converters tend to exhibit fast-scale instability over time domain. The traditional remedy is to impose slope compensation so as to weaken or eliminate this instability. A theoretical principle on the implementation of slope compensation signal is still lacking. Empirical design will induce over compensation frequently, resulting in a large decrease of power factor. In order to tackle this issue, by constructing the discrete-time iterative map of the PFC Boost converter from the viewpoint of bifurcation control theory of nonlinear systems, consequently, the criterion of critical stability for the PFC circuit can be established. Based on this stability criterion, appropriate design of slope compensation can be achieved. Our work indicates that 3 main circuit parameters (i.e. switching cycle, output reference voltage and inductor) determine the effective amplitude design of the slope compensation signal. The results, validated by a large quantity of analytical and numerical studies, show that appropriate slope compensation can be effective in weakening (or controlling) fast-scale bifurcation while maintaining a rather high input power factor. | ZHOU YuFei HUANG JiaCheng WANG ShiBing JIANG Wei CHEN JunNing | 2009 | Science in China(Series F)2009，52，11： | 6 |
| 15 | A comparative study of two porous sponge scaffolds prepared by collagen derived from porcine skin and fish scales as burn wound dressings in a rabbit model显示文摘Collagen is widely used in biomedical applications due to its outstanding properties.In this study,highly porous sponge scaffolds were developed by using porcine skin-derived collagen(PSC)and fish scale-derived collagen(FSC),respectively.The morphology and composition of these PSC and FSC scaffolds were compared.The water uptake ratio of FSC scaffolds reached 47.8,which is 1.7 times of PSC scaffolds.The water vapour transmission rates(WVTR)of PSC and FSC scaffolds were 952.6655.5 and 1090.9677.1 g/m2/day,which could produce a moist healing environment for wounds.Both scaffolds show non-toxicity to L929 fibroblast cells.The burn wound healing efficiency of these two scaffolds was examined in vivo using rabbits.No scars around the wounds were observed after applying PSC and SFC scaffolds.Histopathological studies reveal that the wound treated with PSC and FSC scaffolds showed much better wound recovery than gauze and vaseline gauze groups.It was suggested that FSC scaffolds have great potential as same as PSC to be used as burn wound dressing materials. | Yufei Shi Hongjian Zhang Xin Zhang Zhan Chen Dan Zhao Jun Ma | 2020 | Regenerative Biomaterials2020，7，1： | 6 |
| 16 | Determination of critical slip surface of fractured rock slopes based on fracture orientation data显示文摘The critical slip surface of a fractured rock slope tends to extend along the fractures.Thus,fracture orientation plays a critical role in determining the critical slip surface.Based on fracture orientation data,this paper examines the critical slip surfaces of fractured rock slopes.Given that the surface of a fractured rock slope extends along the fracture surfaces,or the wedges,with each composed of two arbitrary fractures,the critical slip surface is determined via stochastic dynamics.In addition,a fracture frequency method is proposed as a means of analyzing the critical slip surface.According to this method,the critical slip surface slips in whichever direction has the lowest fracture frequency.Based on the stochastic dynamics method and the fracture frequency method,the critical slip surface of the slope is finally determined,that is,the critical slip surface takes the form of a plane passing the slope toe with a dip of 120° and a dip angle of 45°. | ZHANG Wen CHEN JianPing ZHANG Wu L Yan MA YuFei XIONG Hui | 2013 | Science China(Technological Sciences)2013，56，5： | 5 |
| 17 | Passive Localization of Signal Source Based on UAVs in Complex Environment显示文摘For the influence caused by multipath fading and non-line-of-sight(NLOS)transmission,it is challenging to accurately localize a moving signal source in complex environment by using the wireless sensor network(WSN)on the ground.In this paper,we establish a special WSN in the sky to address this challenge,where each sensor is loaded on an unmanned aerial vehicle(UAV)and the operation center of all the UAVs is fixed on the ground.Based on the analyzing of the optimal distribution and the position error calibration of all the sensors,we formulate the localization scheme to estimate the position of the target source,which combines the time difference of arrival(TDOA)method and the frequency difference of arrival(FDOA)method.Then by employing the semidefinite programming approach,we accurately obtain the position and velocity of the signal source.In the simulation,the validity of the proposed method is verified through the performance comparison. | Pengwu Wan Qiongdan Huang Guangyue Lu Jin Wang Qianli Yan Yufei Chen | 2020 | China Communications2020，17，2： | 5 |
| 18 | Modeling of fast charging station equipped with energy storage显示文摘The popularization of EVs(electric vehicles) has brought an increasingly heavy burden to the development of charging facilities. To meet the demand of rapid energy supply during the driving period, it is necessary to establish a fast charging station in public area. However, EVs arrive at the charging station randomly and connect to the distribution network for fast charging, it causes the grid power to fluctuate greatly and the peak-valley loads to alternate frequently, which is harmful to the stability of distribution network. In order to reduce the power fluctuation of random charging, the energy storage is used for fast charging stations. The queuing model is determined to demonstrate the load characteristics of fast charging station, and the state space of fast charging station system is described by Markov chain. After that the power of grid and energy storage is quantified as the number of charging pile, and each type of power is configured rationally to establish the random charging model of energy storage fast charging station. Finally, the economic benefit is analyzed according to the queuing theory to verify the feasibility of the model. | Yu Zhang Yang He Xudong Wang Yufei Wang Chen Fang Hua Xue Chaoming Fang | 2018 | Global Energy Interconnection2018，1，2： | 5 |
| 19 | Pressure distribution guided supercritical wing optimization显示文摘Pressure distribution is important information for engineers during an aerodynamic design process. Pressure Distribution Oriented(PDO) optimization design has been proposed to introduce pressure distribution manipulation into traditional performance dominated optimization.In previous PDO approaches, constraints or manual manipulation have been used to obtain a desirable pressure distribution. In the present paper, a new Pressure Distribution Guided(PDG) method is developed to enable better pressure distribution manipulation while maintaining optimization efficiency. Based on the RBF-Assisted Differential Evolution(RADE) algorithm, a surrogate model is built for target pressure distribution features. By introducing individuals suggested by suboptimization on the surrogate model into the population, the direction of optimal searching can be guided. Pressure distribution expectation and aerodynamic performance improvement can be achieved at the same time. The improvements of the PDG method are illustrated by comparing its design results and efficiency on airfoil optimization test cases with those obtained using other methods. Then the PDG method is applied on a dual-aisle airplane's inner-board wing design. A total drag reduction of 8 drag counts is achieved. | Runze LI Kaiwen DENG Yufei ZHANG Haixin CHEN | 2018 | Chinese Journal of Aeronautics2018，31，9： | 5 |
| 20 | Mechanistic and therapeutic perspectives for cardiac arrhythmias:beyond ion channels显示文摘Cardiac arrhythmias are among the most common causes of death in the world. Foundational studies established the critical role of ion channel disorders in arrhythmias, yet defects in ion channels themselves, such as mutations, may not account for all arrhythmias. Despite the progress made in recent decades, the antiarrhythmic drugs currently available have limited effectiveness,and the majority of these drugs can have proarrhythmic effects. This review describes novel knowledge on cellular mechanisms that cause cardiac arrhythmias, focuses on the dysfunction of subcellular organelles and intracellular logistics, and discusses potential strategies and challenges for developing novel, safe and effective treatments for arrhythmias. | Yufei Wu Jun Li Liang Xu Li Lin Yi-Han Chen | 2017 | Science China(Life Sciences)2017，60，4： | 4 |
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