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| 1 | Oxidation Modification of Polyacrylonitrile-Based Carbon Fiber and Its Electro-Chemical Performance as Marine Electrode for Electric Field Test显示文摘A novel sensor for ocean electric field testing has been fabricated by polyacrylonitrile-based on carbon fibers with electro-chemical oxidation.The surface profile characteristics of the carbon fibers were characterized by scanning electron microscope,Fourier transform infrared spectra and contact angle.Cyclic voltammetry and Tafel curves have been used to study its electro-chemical performances.Two identical electrodes in sea water as the electric field sensor will swiftly respond to applied electric field which causes positive and negative ions to move in opposite direction,resulting in a electric potential difference(ΔE).Test result indicates that the offset potential is typically below 1 m V with a drift of 60-170μVd^-1.Typical self noise level is 1.07 nV√Hz^(1/2)@1 Hz.The electric field response indicates that the modified electrode pair shows better response to AC sine signal of amplitude and frequency(5 mV and 1 mHz)respectively than its blank.The electric field response model of the modified electrodes is creatively presented according to its electric double layer capacitance and Faraday pseudo-capacitance.Many advantages of the carbon fiber electric field electrode will make it have potential application prospect. | ZAI Xuerong LIU Ang TIAN Yuhua CHAI Fanggang FU Yubin | 2020 | Journal of Ocean University of China2020，19，2： | 7 |
| 2 | Distribution and Geochemical Characteristics of Hydrogen in Natural Gas from the Jiyang Depression, Eastern China显示文摘Hydrogen gas accelerates hydrocarbon generation, but little is known about its distribution and origin in petroliferous basins, which has hindered the further exploration.Taken the Jiyang Depression in eastern China as an example, this study collected natural gas from different tectonic units, and analyzed various geochemical characters including gas contents, and carbon and hydrogen isotopic composition.The result shows that:(1) hydrogen gas is widespread distributed, but its content is very low, which typically ranges from 0.01% to 0.1% in this region;(2) the ratios of H2/3He, indicative of the origins of hydrogen gas, suggest that mantle-derived hydrogen is dominant.Even in tectonically stable areas absent with deep fluid activities, there is also mantle-derived;(3) the isotopic composition of hydrogen falls in the range of –798‰ to –628‰(relative to VSMOW standard).In areas with deep-derived fluids, the hydrogen gas has a similar isotopic composition with the previously documented deep-sourced gas, with lighter isotopic composition.In contrast, hydrogen gas has a heavier isotopic composition in relatively stable areas.The isotopic signatures suggest that there is a mixture of mantle- and crust-derived hydrogen gas in the relatively stable area, which is consistent with the H2/3He ratios.Therefore, it is clear that the hydrogen gas has a much wider distribution than found in the deep-derived fluid area, resulting in a much broader area with hydrogenating effect for resource rock.This understanding will provide new insights for hydrocarbon generation research and resource assessment in petroliferous basins. | MENG Qingqiang SUN Yuhua TONG Jianyu FU Qi ZHU Jun ZHU Dongya JIN Zhijun | 2015 | Acta Geologica Sinica(English Edition)2015，89，5： | 5 |
| 3 | Fractal Dimension and Fractals in Ocean Engineering显示文摘- This paper discusses the application of fractal dimension and fractals in ocean engineering. To handle some ocean environment problems, the existing fractal method, in which the fractal dimension is a constant, can be used. For some complicated problems in ocean engineering, this paper presents the concept of the variable dimension fractals (D = f(r)), i. e., the fractal dimension D is the function of characteristic scale r instead of a constant. By using variable dimension fractals, several deformation and stress states of offshore structures are described. | Fu Yuhua Senior Engineer, China Offshore Oil Engineering Corporation, P. O. Box 4709, Beijing, 100027 | 1994 | China Ocean Engineering1994，9，3： | 5 |
| 4 | Degradation of lipid droplets by chimeric autophagy-tethering compounds显示文摘Degrading pathogenic proteins by degrader technologies such as PROTACs(proteolysis-targeting chimeras)provides promising therapeutic strategies,but selective degradation of non-protein pathogenic biomolecules has been challenging. | Yuhua Fu Ningxie Chen Ziying Wang Shouqing Luo Yu Ding Boxun Lu | 2021 | Cell Research2021，31，9： | 5 |
| 5 | Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models显示文摘 | Meng Yu Yuhua Fu Yijian Liang Haikun Song Yao Yao Peng Wu Yuwei Yao Yuyin Pan Xue Wen Lixiang Ma Saiyin Hexige Yu Ding Shouqing Luo Boxun Lu | 2017 | Cell Research2017，27，12： | 5 |
| 6 | The molecular determinants governing the immunogenicity of Japanese encephalitis live attenuated vaccines显示文摘In the course of isolating the attenuated Japanese encephalitis vaccine SA14-14-2,two attenuated strains SA14-9-7 and SA14-5-3 were also obtained that elicited low antibody responses in humans(o10%and 62%,respectively)and exerted much weaker immune protection in animal challenge experiments.However,the reason for these differences remains unknown.In order to understand why SA14-14-2 is superior to SA14-9-7 and SA14-5-3,we employed a reverse genetics method to identify the key mutations in the virus genome that determine the immunogenicity of live attenuated Japanese encephalitis viruses.We first sequenced the full genomic sequences of SA14-9-7 and SA14-5-3 and found mutations that changed four amino-acid base pairs when compared to the envelope gene of SA14-14-2.We mutated the genome of SA14-14-2 to generate these mutations both singly(E-177,E-264,E-279 and E-315)and in combination(E-177/264,E-279/315 and E-177/264/279/315)and tested these mutants along with parental strains SA14-14-2,SA14-9-7 and SA14-5-3 for their immunogenicity in vivo.When mice were immunized with SA14-9-7 and SA14-5-3,lower levels of neutralizing antibodies were generated compared with the immune response to SA14-14-2.Furthermore,SA14-5-3 was more immunogenic than SA14-9-7,which replicated the results previously seen in humans.Point mutations E-177,E-264,E-279 and E-315 diminished the immunogenicity of SA14-14-2 with E-264 and E-315,contributing the most to this phenotype.The mutant rJEV(E-177/E-264/E-279/E-315)containing all four point mutations exhibited the lowest immunogenicity with a seroconversion rate of 0 at an inoculation dose of 103 PFU(plaque-forming unit).We have identified the key amino acids in the envelope protein that account for the superior immunogenicity of SA14-14-2. | Yuhua Li Yin Fu Xinyu Liu Huiqiang Yang Yongxin Yu Lili Jia Xuguang Li Aaron Farnsworth Junzhi Wang | 2017 | Signal Transduction and Targeted Therapy2017，2，1： | 3 |
| 7 | Unified Water Gravity Wave Theory and Improved Linear Wave显示文摘- Based on Least Square Method, this paper presents variational principle for handling various water gravity wave theories and the unified water gravity wave theory was given. By using this variational principle of unified water wave theory, two kinds of improved linear waves were derived. The first one uses the same boundary conditions which were applied to derive 5-order Stokes wave. The second one uses the accurate boundary conditions (Eqs. 11 and 12). The two improved linear waves were compared with the existing linear wave. | Fu Yuhua Senior Engineer, Structural Engineering Department, China Offshore Oil Development and Engineering Corp., Beijing | 1992 | China Ocean Engineering1992，7，1： | 3 |
| 8 | Preparation and physical properties of soy protein isolate and gelatin composite films显示文摘 | Na Cao Yuhua Fu Junhui He | 2006 | Food Hydrocolloids2006，，7： | 3 |
| 9 | Constructing a Genetic Linkage Map Using an F1 Population of Non-inbred Parents in Cassava (Manihot esculenta Crantz)显示文摘 | Xin Chen Zhiqiang Xia Yuhua Fu Cheng Lu Wenquan Wang | 2010 | Plant Molecular Biology Reporter2010，，4： | 2 |
| 10 | A NEW WAY FOR DERIVING SOLITARY WAVE显示文摘This paper presents a new way for deriving solitary wave by using variational principle, which not only can be used to derive solitary wave according to Original Mathematical Equations (OME), but also can be used to derive solitary wave according to the Wave Equation (WE) derived from OME. With the same condition of wave height and water depth, WE-solitary wave and OME-solitary wave are compared in this paper. | Fu Yuhua Engineer, Structure Eng. Dept, China Offshore Oil Development And Engineering Corp., Beijing | 1989 | China Ocean Engineering1989，4，3： | 2 |
| 11 | A NEW WAY FOR DERIVING HIGH ORDER STOKES WAVES显示文摘Variational principle for non-vortex, non-linear wave theories is established in this paper. By using this variational principle and related functional minimum condition, the fifth and sixth order Stokes Vaves are given as an example and the results are compared with those in Reference (Skjel-breia, 1961). | Fu Yuhua Engineer, Engineering Dept., China National Offshore Oil Corp., Beijing | 1989 | China Ocean Engineering1989，4，1： | 2 |
| 12 | Vibration Effect and Damage Evolution Characteristics of Tunnel Surrounding Rock Under Cyclic Blasting Loading显示文摘Model test studies based on the similarity theory were conducted to investigate vibration effect and damage evolution characteristics of tunnel surrounding rock under push-type cyclic blasting excavation.The model was constructed with a ratio of 1∶15.By simulating the tunnel excavation of push-type cyclic blasting,the influence of the blasting parameter change on vibration effect was explored.The damage degree of tunnel surrounding rock was evaluated by the change of the acoustic wave velocity at the same measuring point after blasting.The relationship between the damage evolution of surrounding rock and blasting times was established.The research results show that:(1)In the same geological environment,the number of delay initiation is larger,the main vibration frequency of blasting seismic wave is higher,and the attenuation of high frequency signal in the rock and soil is faster.The influence of number of delay initiation on blasting vibration effect cannot be ignored;(2)Under push-type cyclic blasting excavation,there were great differences in the decreasing rates of acoustic wave velocity of the measuring points which have the same distance to the blasting region at the same depth,and the blasting damage ranges of surrounding rock were typically anisotropic at both depth and breadth;(3)When blasting parameters were basically kept as the same,the growth trend of the cumulative acoustic wave velocity decreasing rate at the measuring point was nonlinear under different cycle blasting excavations;(4)There were nonlinear evolution characteristics between the blasting cumulative damage(D)of surrounding rock and blasting times(n)under push-type cyclic blasting loading,and different measuring points had corresponding blasting cumulative damage propagation models,respectively.The closer the measuring point was away from the explosion source,the faster the cumulative damage extension.Blasting cumulative damage effect of surrounding rock had typically nonlinear evolution properties and anisotropic characteristics. | Guosheng Zhong Yongzhong Lou Yuhua Fu | 2017 | Journal of Beijing Institute of Technology2017，26，3： | 1 |
| 13 | Analysis of QTL for yield-related traits in cassava using an F 1 population from non-inbred parents显示文摘 | Xin Chen Yuhua Fu Zhiqiang Xia Li Jie Haiyan Wang Cheng Lu Wenquan Wang | 2012 | Euphytica2012，，2： | 1 |
| 14 | Mechanical properties of gelatin films cross-linked, respectively, by ferulic acid and tannin acid显示文摘 | Na Cao Yuhua Fu Junhui He | 2006 | Food Hydrocolloids2006，，4： | 1 |
| 15 | Preparation and physical properties of soy protein isolate and gelatin composite films显示文摘 | Na Cao Yuhua Fu Junhui He | 2006 | Food Hydrocolloids2006，，7： | 1 |
| 16 | Interleukin 6 protects H<sub>2</sub>O<sub>2</sub>‐induced cardiomyocytes injury through upregulation of prohibitin via STAT3 phosphorylation显示文摘 | Yuhua Jia Fenghua Zhou Peng Deng Qin Fan Chunhua Li Yawei Liu Xiuqiong Fu Yingchun Zhou Xin Xu Xuegang Sun | 2012 | Cell Biochem Funct2012，，5： | 1 |
| 17 | Bioluminescence imaging of caspase-3 activity in mouse liver显示文摘 | Qiuxia Fu Xiangguo Duan Shaoduo Yan Licui Wang Yong Zhou Shuaizheng Jia Juan Du Xiaohui Wang Yuhua Zhang Linsheng Zhan | 2013 | Apoptosis2013，，8： | 1 |
| 18 | Unascertained measurement classifying model of goaf collapse prediction显示文摘 | DONG Longjun PENG Gangjian FU Yuhua | 2008 | Journal of Coal Science & Engineering2008，14，2： | 1 |
| 19 | Mechanical properties of gelatin films cross-linked,respectively,by ferulic acid and tannin acid显示文摘 | Cao Na Fu Yuhua He Junhui | 2007 | Food Hydrocolloids2007，21，4： | 1 |
| 20 | Optimum fifth order Stokes wave theory显示文摘OptimumfifthorderStokeswavetheory￥FuYuhua(ChinaOffshoreOilDevelopment&EngineeringCorporation,P.O.Box4709,Beijing100027,China)... | Fu Yuhua(China Offshore Oil Development & Engineering Corporation, P. O. Box 4709, Beijing 100027, China) | 1995 | Acta Oceanologica Sinica1995，14，1： | 1 |
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