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| 1 | Progression of remnant gastric cancer is associated with duration of follow-up following distal gastrectomy显示文摘AIM: To re-evaluate the recent clinicopathological features of remnant gastric cancer (RGC) and to develop desirable surveillance programs. METHODS: Between 1997 and 2008, 1149 patients underwent gastrectomy for gastric cancer at the Department of Digestive Surgery, Kyoto Prefectural University of Medicine, Japan. Of these, 33 patients underwent gastrectomy with lymphadenectomy for RGC. Regarding the initial gastric disease, there were 19 patients with benign disease and 14 patients with gastric cancer. The hospital records of these patients were reviewed retrospectively. RESULTS: Concerning the initial gastric disease, the RGC group following gastric cancer had a shorter interval [P < 0.05; gastric cancer vs benign disease: 12 (2-22) vs 30 (4-51) years] and were more frequently reconstructed by Billroth-Ⅰ procedure than those following benign lesions (P < 0.001). Regarding reconstruction, RGC following Billroth-Ⅱ reconstruction showed a longer interval between surgical procedures [P < 0.001; Billroth-Ⅱ vs Billroth-Ⅰ: 32 (5-51) vs 12 (2-36) years] and tumors were more frequently associated with benign disease (P < 0.001) than those following Billroth-Ⅰ reconstruction. In tumor location of RGC, after Billroth-Ⅰ reconstruction, RGC occurred more frequently near the suture line and remnant gastric wall. After Billroth-Ⅱ reconstruction, RGC occurred more frequently at the anastomotic site. The duration of follow-up was significantly associated with the stage of RGC (P < 0.05). Patients diagnosed with early stage RGC such as stage Ⅰ-Ⅱ tended to have been followed up almost every second year. CONCLUSION: Meticulous follow-up examination and early detection of RGC might lead to a better prognosis. Based on the initial gastric disease and the procedure of reconstruction, an appropriate follow-up interval and programs might enable early detection of RGC. | Shuhei Komatsu Daisuke Ichikawa Kazuma Okamoto Daito Ikoma Masahiro Tsujiura Yukihisa Nishimura Yasutoshi Murayama Atsushi Shiozaki Hisashi Ikoma Yoshiaki Kuriu Masayoshi Nakanishi Hitoshi Fujiwara Toshiya Ochiai Yukihito Kokuba Eigo Otsuji | 2012 | World Journal of Gastroenterology2012,18,22: | 25 |
| 2 | Surgical treatment of hepatocellular carcinoma with severe intratumoral arterioportal shunt显示文摘We report a case of hepatocellular carcinoma (HCC) that caused a severe arterioportal shunt (APS). A 49-year-old man was admitted to hospital due to esophagogastric variceal hemorrhage and HCC, and underwent endoscopic variceal ligation (EVL) and endoscopic injection sclerotherapy (EIS). He was then referred to our hospital. Abdominal computed tomography revealed a lowdensity lesion in the posterior segment of the liver and an intratumoral APS, which caused portal hypertension. Although the patient underwent EVL, EIS, Hassab’s operation, and transcatheter arterial embolization for APS, he vomited blood due to rupture of esophagogastric varices. Right hepatectomy was performed for the treatment of HCC and APS, although the indocyanine green retention value at 15 min after intravenous injection was poor (30%). The patient’s postoperative course was uneventful. Eventually, APS disappeared and the esophagogastric varices improved. | Hiromichi Ishii Teruhisa Sonoyama Shingo Nakashima Hiroyuki Nagata Atsushi Shiozaki Yoshiaki Kuriu Hisashi Ikoma Masayoshi Nakanishi Daisuke Ichikawa Hitoshi Fujiwara Kazuma Okamoto Toshiya Ochiai Yukihito Kokuba Chohei Sakakura Eigo Otsuji | 2010 | World Journal of Gastroenterology2010,16,25: | 11 |
| 3 | Impaired coronary microvascular endothelial function in men with metabolic syndrome显示文摘AIM: To assess coronary endothelial function of conduit and resistance vessels in patients with metabolic syndrome (MS). METHODS: Seventy-eight men (mean age, 57 years) with chest pain and angiographically normal coronary arteries were included in the study. Patients with coronary spastic angina were excluded. Changes in coronary artery diameter and coronary blood flow (CBF) in response to acetylcholine (ACh) were determined using quantitative coronary angiography and Doppler velocity measurements. Coronary flow reserve was calculated as the ratio of coronary blood velocity after adenosine triphosphate infusion relative to baseline values. Patients were divided into two groups based on the presence or absence of MS. RESULTS: There were 24 patients in the MS group (31%). The increase in CBF in response to ACh infusion was impaired in the MS group (P < 0.0001) compared to the non-MS group, whereas changes in coronary artery diameter in response to ACh infusion did not differ between the two groups. Multivariate regression analysis revealed that MS was a significant factor associated with the lesser change in CBF induced by ACh infusion at 30 μg/min (P < 0.0001, r 2 = 0.46). CONCLUSION: Coronary endothelial dysfunction was present at the level of resistance vessels but not conduit vessels in the MS patients included in our study. | Hiroki Teragawa Naoya Mitsuba Kenji Nishioka Kentaro Ueda Shingo Kono Yukihito Higashi Kazuaki Chayama Yasuki Kihara | 2010 | World Journal of Cardiology2010,2,7: | 2 |
| 4 | Evaluation of the sperm DNA fragmentation index in infertile Japanese men by in-house flow cytometric analysis显示文摘Semen analysis has long been used to evaluate male fertility.Recently,several sperm function tests have been developed.Of those,the sperm DNA fragmentation index(DFI),which describes the status of the sperm DNA,is thought to be a suitable parameter for evaluating male fertility.However,there have been no large-scale studies on the sperm DFI of Japanese men.Therefore,we investigated the feasibility of using an in-house flow cytometry-based sperm DFI analysis based on the sperm DNA fragmentation test of sperm chromatin structure assay(SCSA)to assess male fertility in Japan.This study enrolled 743 infertile and 20 fertile Japanese men.To evaluate reproducibility,inter-and intraobserver precision was analyzed.A receiver operating characteristic curve analysis was used to set a cutoff value for the sperm DFI to identify men who could father children by timed intercourse or intrauterine insemination.The variability of the sperm DFI among fertile volunteers was determined.The relationship between semen parameters and the sperm DFI was assessed by Spearman’s rho test.A precision analysis revealed good reproducibility of the sperm DFI.The cutoff value of sperm DNA fragmentation in infertile men was 24.0%.Semen volume had no relationship with the sperm DFI.Sperm concentration,sperm motility,total motile sperm count,and percentage of normal-shaped sperm were significantly and negatively correlated with the sperm DFI.The median sperm DFI was smaller in fertile volunteers(7.7%)than that in infertile men(19.4%).Sperm DNA fragmentation analysis can be used to assess sperm functions that cannot be evaluated by ordinary semen analysis. | Akiyoshi Osaka Hiroshi Okada Sae Onozuka Takashi Tanaka Toshiyuki Iwahata Yukihito Shimomura Yoshitomo Kobori Kazutaka Saito Kouhei Sugimoto | 2022 | Asian Journal of Andrology2022,24,1: | 2 |
| 5 | Differences of the Lymphatic Distribution and Surgical Outcomes Between Remnant Gastric Cancers and Primary Proximal Gastric Cancers显示文摘 | Shuhei Komatsu Daisuke Ichikawa Kazuma Okamoto Daito Ikoma Masahiro Tsujiura Atsushi Shiozaki Hitoshi Fujiwara Yasutoshi Murayama Yoshiaki Kuriu Hisashi Ikoma Masayoshi Nakanishi Toshiya Ochiai Yukihito Kokuba Eigo Otsuji | 2012 | Journal of Gastrointestinal Surgery2012,,3: | 2 |
| 6 | Hypervelocity impact experiments on aerogel dust collector显示文摘 | Yukihito Kitazawa Akira Fujiwara | 1999 | Journal of Geophysical Research1999,104,22: | 1 |
| 7 | Simultaneous temperature measurements of bearing and seal parts of a swash plate type axial piston pump-effects of piston clearance and fluid property 显示文摘 | Kazama Toshiharu Sasaki Hayato Narita Yukihito | 2010 | Journal of Mechanical Science and Technology2010,24,1: | 1 |
| 8 | A case report of metastatic neuroendocrine carcinoma of the right adrenal gland successfully treated with chemotherapy and surgery显示文摘 | Toshiya Ochiai Sosuke Komiyama Hisashi Ikoma Takeshi Kubota Masayoshi Nakanishi Daisuke Ichikawa Shojiro Kikuchi Hitoshi Fujiwara Chohei Sakakura Yukihito Kokuba Teruhisa Sonoyama Eigo Otsuji | 2010 | International Journal of Clinical Oncology2010,,4: | 1 |
| 9 | The configuration of methyl jasmonate affects paclitaxel and baccatinproduction in Taxus cells显示文摘 | Yukihito Y Yasuhiro H Emi N | 2000 | Phyto-chemistry2000,54,: | 1 |
| 10 | Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease显示文摘 | Yukihito Higashi Chikara Goto Takayuki Hidaka Junko Soga Shuji Nakamura Yuichi Fujii Takaki Hata Naomi Idei Noritaka Fujimura Kazuaki Chayama Yasuki Kihara Akira Taguchi | 2009 | Atherosclerosis2009,,2: | 1 |
| 11 | New tubular bioabsorbable knitted airway stent: biocompatibility and mechanical strength显示文摘 | Kenichirou M masnshi K | 2002 | J Thorac Cardiovas Surg2002,123,1: | 1 |
| 12 | Endothelial progenitor cells: Therapeutic target for cardiovascular diseases显示文摘 | Takashi U Yukihito H | 2008 | J Pharmacol Sci2008,108,: | 1 |
| 13 | Short-term outcomes of laparoscopic intersphincteric resection from a phase II trial to evaluate laparoscopic surgery for stage 0/I rectal cancer: Japan Society of Laparoscopic Colorectal Surgery Lap RC显示文摘 | Shoichi Fujii Seiichiro Yamamoto Masaaki Ito Shigeki Yamaguchi Kazuhiro Sakamoto Yusuke Kinugasa Yukihito Kokuba Junji Okuda Kenichi Yoshimura Masahiko Watanabe | 2012 | Surgical Endoscopy2012,,11: | 1 |
| 14 | Effect of differ- ent intensities of exercise on endothelium-dependent vasodi- lation in humans: role of endothelium-dependent nitric oxide and oxidative stress 显示文摘 | Chikara G Yukihito H Masashi K | 2003 | Circulation2003,108,5: | 1 |
| 15 | Molecular markers distinguish bone marrow mesenchymal stem cells from fibroblasts显示文摘 | Masakazu Ishii Chika Koike Akira Igarashi Katsuyuki Yamanaka Haiou Pan Yukihito Higashi Hiroyuki Kawaguchi Masaru Sugiyama Nobuyuki Kamata Tomoyuki Iwata Takehiro Matsubara Kozo Nakamura Hidemi Kurihara Koichiro Tsuji Yukio Kato | 2005 | Biochemical and Biophysical Research Communications2005,,1: | 1 |
| 16 | Fully enzymatic method for determining 1,5-anhydro-D-glucitol in serum显示文摘 | Yukihito Fukumura | 1994 | Clinical chemistry1994,40,11: | 1 |
| 17 | Clinicopathologic Features and Risk Factors for Extrahepatic Recurrences of Hepatocellular Carcinoma After Curative Resection显示文摘 | Toshiya Ochiai Hisashi Ikoma Kazuma Okamoto Yukihito Kokuba Teruhisa Sonoyama Eigo Otsuji | 2012 | World Journal of Surgery2012,,1: | 1 |
| 18 | Measurements of baseline and follow-up concentrations of cardiac troponin-T and brain natriuretic peptide in patients with heart failure from various etiologies显示文摘 | Ryoji Taniguchi Yukihito Sato Yukiko Nishio Takeshi Kimura Toru Kita | 2006 | Heart and Vessels2006,,6: | 1 |
| 19 | New tubular bioabsorbable knitted airway stent:biocompatibility and mechanical strength显示文摘 | Yukihito S Kenichiron M masashi K | 2002 | Thorac Cardiovas Surg2002,123,1: | 1 |
| 20 | Simulation of rolling contact fatigue strength for traction drive elements 显示文摘 | Yukihito Narita Masashi Yamanaka Toshiharu Kazama | 2013 | Journal of Advanced Mechanical Design Systems and Manufacturing2013,7,3: | 1 |