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| 1 | Clinical impact of surveillance for head and neck cancer in patients with esophageal squamous cell carcinoma显示文摘AIM To evaluate the clinical impact of surveillance for head and neck(HN) region with narrow band imaging(NBI) in patients with esophageal squamous cell carcinoma(ESCC).METHODS Since 2006, we introduced the surveillance for HN region using NBI for all patients with ESCC beforetreatment, and each follow-up. The patients with newly diagnosed stage Ⅰ to Ⅲ ESCC were enrolled and classified into two groups as follows: Group A(no surveillance for HN region); between 1992 and 2000), and Group B (surveillance for HN region with NBI; between 2006 and 2008). We comparatively evaluated the detection rate of superficial head and neck squamous cell carcinoma (HNSCC), and the serious events due to metachronous advanced HNSCC during the follow-up.RESULTS A total 561 patients(group A: 254, group B: 307) were enrolled. Synchronous superficial HNSCC was detected in 1 patient (0.3%) in group A, and in 12 (3.9%) in group B (P=0.008). During the follow up period, metachronous HNSCC were detected in 10 patients(3.9%) in group A and in 30 patients(9.8%) in group B(P = 0.008). All metachronous lesions in group B were early stage, and 26 patients underwent local resection, however, 6 of 10 patients (60%) in group A lost their laryngeal function and died with metachronous HNSCC.CONCLUSION Surveillance for the HN region by using NBI endoscopy increase the detection rate of early HNSCC in patients with ESCC, and led to decrease serious events related to advanced metachronous HNSCC. | Hiroyuki Morimoto Tomonori Yano Yusuke Yoda Yasuhiro Oono Hiroaki Ikematsu Ryuichi Hayashi Atsushi Ohtsu Kazuhiro Kaneko | 2017 | World Journal of Gastroenterology2017，23，6： | 12 |
| 2 | Esophagotracheal fistula caused by gastroesophageal reflux 9 years after esophagectomy显示文摘Fistula between digestive tract and airway is one of the complications after esophagectomy with lymph node dissection. A case of esophagotracheal fistula secondary to esophagitis 9 years after esophagectomy and gastric pull-up for treatment of esophageal carcinoma is described. It was successfully treated with transposition of a pedicled pectoralis major muscle flap. | Kiyotomi Maruyama Satoru Motoyama Manabu Okuyama Yusuke Sato Kaori Hayashi Yoshihiro Minamiya Jun-ichi Ogawa | 2007 | World Journal of Gastroenterology2007，13，5： | 2 |
| 3 | Defini- tions of power quality levels and the simplest approach for un- bundled power quality services显示文摘 | Toshifiimi Ise Yusuke Hayashi and Kiichiro Tsuji | 2000 | Harmonics and Quality of Power2000，，2： | 1 |
| 4 | Usefulness of the neutrophil/lymphocyte ratio measured preoperatively as a predictor of peritoneal metastasis in patients with advanced gastric cancer显示文摘 | Yusuke Nakayama Naoto Gotohda Hidehito Shibasaki Shogo Nomura Takahiro Kinoshita Ryuichi Hayashi | 2014 | Surgery Today2014，，11： | 1 |
| 5 | Yucasin is a potent inhibitor of YUCCA , a key enzyme in auxin biosynthesis显示文摘 | Takeshi Nishimura Ken‐ichiro Hayashi Hiromi Suzuki Atsuko Gyohda Chihiro Takaoka Yusuke Sakaguchi Sachiko Matsumoto Hiroyuki Kasahara Tatsuya Sakai Jun‐ichi Kato Yuji Kamiya Tomokazu Koshiba | 2014 | Plant J2014，，3： | 1 |
| 6 | Biochemical and immunohistochemical characterization of Mimosa annexin显示文摘 | Daisuke Hoshino Asami Hayashi Yusuke Temmei Nobuyuki Kanzawa Takahide Tsuchiya | 2004 | Planta2004，，5： | 1 |
| 7 | Structures of acidic polysaccharides from Basella rubra L. and their antiviral effects显示文摘 | Cai-Xia Dong Kyoko Hayashi Yusuke Mizukoshi Jung-Bum Lee Toshimitsu Hayashi | 2011 | Carbohydrate Polymers2011，，3： | 1 |
| 8 | Structures and anti-HSV-2 activities of neutral polysaccharides from an edible plant, Basella rubra L.显示文摘 | Cai-Xia Dong Kyoko Hayashi Yusuke Mizukoshi Jung-Bum Lee Toshimitsu Hayashi | 2011 | International Journal of Biological Macromolecules2011，，1： | 1 |
| 9 | Molecular Biotechnology显示文摘 | Jiro Kikuchi Yusuke Furukawa Nakanobu Hayashi | 2003 | 23:203-2122003，23，： | 1 |
| 10 | Hypomagnesemia in Type 2 Diabetic Nephropathy显示文摘 | Yusuke Sakaguchi Tatsuya Shoji Terumasa Hayashi Akira Suzuki Morihiro Shimizu Kensuke Mitsumoto Hiroaki Kawabata Kakuya Niihata Noriyuki Okada Yoshitaka Isaka Hiromi Rakugi Yoshiharu Tsubakihara | 2012 | Diabetes Care2012，，7： | 1 |
| 11 | Guidance for peptide vaccines for the treatment of cancer显示文摘 | Yoshiyuki Yamaguchi Hiroki Yamaue Takuji Okusaka Kiyotaka Okuno Hiroyuki Suzuki Tomoaki Fujioka Atsushi Otsu Yasuo Ohashi Rumiko Shimazawa Kazuto Nishio Junji Furuse Hironobu Minami Takuya Tsunoda Yuzo Hayashi Yusuke Nakamura | 2014 | Cancer Sci2014，，： | 1 |
| 12 | Effects of nitric oxide on mucosal barrier dysfunction during early phase of intestinal ischemia/reperfusion显示文摘 | Yusuke Takizawa Hisanao Kishimoto Takuya Kitazato Mikio Tomita Masahiro Hayashi | | European Journal of Pharmaceutical Sciences0，，： | 1 |
| 13 | Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy显示文摘 | Yuka Ikegame Kentaro Yamashita Shin-Ichiro Hayashi Hiroshi Mizuno Masahiro Tawada Fukka You Kiyofumi Yamada Yoshitaka Tanaka Yusuke Egashira Shigeru Nakashima Shin-Ichi Yoshimura Toru Iwama | 2011 | Cytotherapy2011，，6： | 1 |
| 14 | Changes in protein and mRNA expression levels of claudin family after mucosal lesion by intestinal ischemia/reperfusion显示文摘 | Yusuke Takizawa Hisanao Kishimoto Takuya Kitazato Mikio Tomita Masahiro Hayashi | 2012 | 2012 (1-2)2012，，1： | 1 |
| 15 | Effects of Free Time on Quality of Life in Elderly Caregivers显示文摘Caregivers who contribute to health care of their patients are significantly more likely to experience emotional difficulty,physical difficulty,and financial difficulty,than caregivers who do not contribute.This study aimed to examine the effects of free time on health-related quality of life among elderly caregivers of dementia patients.In the intervention group,caregivers set aside free time every 30 minutes three times a week,while continuing to care for patients.During the free time,caregivers were free to spend time at home and do whatever they wanted.The control group received only usual care.The intervention period was six months.The Vitality subscale score of the SF-36 decreased significantly in the intervention group,despite more than half(57.1%)of participants showing improvements or no change in the rank of this subscale relative to baseline,as assessed by the Wilcoxon signed-rank test(not significant).Caregivers indicated that daily caregiving resulted in an accumulation of physical fatigue,and they continued to have little mental leeway.Caregivers also had difficulty securing free time,which may have hindered improvements to their vitality.There is a need to develop a home-based program that can alleviate caregiver stress and improve their quality of life. | Akemi Hirano Yusuke Suzuki Toshio Hayashi Koichiro Ina Joji Onishi | 2021 | Journal of Geriatric Medicine2021，3，1： | 0 |
| 16 | Factors Affecting Catecholamines in Caregivers of Patients with Dementia显示文摘Background:Caregivers of dementia patients have significantly higher levels of serum IL-6 and CRP compared to non-caregivers,and the accumulation of everyday stressors reportedly promotes the induction of inflammatory markers.However,few studies have identified factors that affect catecholamine levels in caregivers who experience a combination of physical and mental stress from caregiving.Purpose:This study aimed to identify physical factors that impact catecholamine levels in caregivers of dementia patients.Methods:Participants were elderly caregivers living together with elderly Alzheimer’s-type dementia patients.We performed logistic regression analysis,with levels of adrenaline,noradrenaline,and dopamine(indicators of catecholamine)as dependent variables.Results:Caregiver BMI had a significant impact on adrenaline levels(OR:0.792;95%CI:0.654-0.960)and noradrenaline levels(OR:1.210;95%CI:1.009-1.451),whereas age had a significant impact on dopamine levels(OR:1.162;95%CI:1.019-1.324).Discussion:While caregiver BMI significantly impacted adrenaline and noradrenaline levels,the mechanism underlying these relationships is unclear.One possibility is that obesity(BMI)and a rise in sympathetic nerve activity contributed to hypertension.Our findings suggest that chronic stress in elderly caregivers may potentially impair the dopaminergic activation system in the brain.Conclusion:There is a need to identify factors which increase BMI in caregivers.Future studies aimed at gaining a better understanding of the lifestyle habits of caregivers and intervention studies aimed at reducing their BMI are warranted. | Akemi Hirano Yusuke Suzuki Toshio Hayashi Koichiro Ina Joji Onishi | 2021 | Journal of Geriatric Medicine2021，3，1： | 0 |
| 17 | Analysis and Prototyping of Multicellular DC-DC Transformer for Environmentally Friendly Data Centers显示文摘 | Yusuke Hayashi Tamotsu Ninomiya | 2016 | Journal of Energy and Power Engineering2016，10，5： | 0 |
| 18 | Fundamental Study of High Step-down Non-isolated Multicellular DC-DC Converter for Future DC Distribution Systems显示文摘 | Yusuke Hayashi Yoshikatsu Matsugaki Tamotsu Ninomiya | 2017 | Journal of Energy and Power Engineering2017，11，9： | 0 |
| 19 | Effectiveness of Optimal Arrangement of the Residences Operated by Reactive Power Control for a Clustered Grid-Interconnected PV System显示文摘 | Yusuke Miyamoto Yasuhiro Hayashi | 2013 | Journal of Energy and Power Engineering2013，7，7： | 0 |
| 20 | Design Consideration for High Power Density GaN Buck-Rectifier in ISOP-IPOS Converter based dc Distribution, System显示文摘 | Yusuke Hayashi Hiroshi Iso Daisuke Hara Akira Matsumoto | 2015 | Journal of Energy and Power Engineering2015，9，6： | 0 |
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