|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Microfluidic actuators based on temperature-responsive hydrogels显示文摘The concept of using stimuli-responsive hydrogels to actuate fluids in microfluidic devices is particularly attractive,but limitations,in terms of spatial resolution,speed,reliability and integration,have hindered its development during the past two decades.By patterning and grafting poly(N-isopropylacrylamide)PNIPAM hydrogel films on plane substrates with a 2μm horizontal resolution and closing the system afterward,we have succeeded in unblocking bottlenecks that thermo-sensitive hydrogel technology has been challenged with until now.In this paper,we demonstrate,for the first time with this technology,devices with up to 7800 actuated micro-cages that sequester and release solutes,along with valves actuated individually with closing and opening switching times of 0.6±0.1 and 0.25±0.15 s,respectively.Two applications of this technology are illustrated in the domain of single cell handling and the nuclear acid amplification test(NAAT)for the Human Synaptojanin 1 gene,which is suspected to be involved in several neurodegenerative diseases such as Parkinson’s disease.The performance of the temperature-responsive hydrogels we demonstrate here suggests that in association with their moderate costs,hydrogels may represent an alternative to the actuation or handling techniques currently used in microfluidics,that are,pressure actuated polydimethylsiloxane(PDMS)valves and droplets. | Loïc D'Eramo Benjamin Chollet Marie Leman Ekkachai Martwong Mengxing Li Hubert Geisler Jules Dupire Margaux Kerdraon Clémence Vergne Fabrice Monti Yvette Tran Patrick Tabeling | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 2 | Pulmonary function following high dose radiotherapy of non small cell lung cancer 显示文摘 | Katrien D J Yvette S Lieshen J B | 2003 | Int J Radiat Oncol Biol Phys2003，55，5： | 1 |
| 3 | Neut- rophil elastase targets virulence factors of enterobacteria 显示文摘 | Yvette Weinrauch Doreen Drujan Steven D Shapiro | 2002 | Nature2002，417，6884： | 1 |
| 4 | Cognitive Improvement Following Treatment in Late-Life Depression: Relationship to Vascular Risk and Age of Onset显示文摘 | Deanna M. Barch Gina D?Angelo Carl Pieper Consuelo H. Wilkins Kathleen Welsh-Bohmer Warren Taylor Keith S. Garcia Kenneth Gersing P. Murali Doraiswamy Yvette I. Sheline | 2012 | American Journal of Geriatric Psychiatry2012，，8： | 1 |
| 5 | A Multiple-Indicator Multi-ple-Cause Model for Posttraumatic Stress Reactions:Personali-ty Coping,and Maladjustment显示文摘 | Man CC Ian D Yvette E | 2005 | Psychoso-mat Med2005，67，2： | 1 |
| 6 | Elevated n-terminal pro-b- type natriuretie peptide levels : the effect of chronic obstructive pulmonary disease显示文摘 | Yvette R B van Gestel M Don D S | 2009 | JACC2009，53，5： | 1 |
| 7 | Depression and pregnancy stressors affect the association between abuse and postpartum depression显示文摘 | Yvette Lacoursiere D Hurst KP Barrett-Connor E | 2011 | Matern Child Health J2011，17，5： | 1 |
| 8 | Flash detection/identification of pathogens, bacterial spores and bioterrorism agent biomarkers from clinical and environmental matrices显示文摘 | David C White Cory A Lytle Ying-Dong M Gan Yvette M Piceno Michael H Wimpee Aaron D Peacock Carol A Smith | 2002 | Journal of Microbiological Methods2002，，2： | 1 |
| 9 | Pedunculated atypical leiomyoma presenting as a hemoperitoneum显示文摘 | Yvette La Coursiere D Chin HG | 2005 | J Gynecol Surg2005，21，1： | 1 |
| 10 | Perceived Constraints and Social Support for Active Leisure Among Mothers With Young Children显示文摘 | Brown Peter R Brown Wendy J Miller Yvette D | 2001 | Leisure Sciences2001，23，3： | 1 |
| 11 | Oxygen free radical scavenger capacity in aqueous models of different procyanidins from grape seeds 显示文摘 | Jorge M R D S Nicole D Yvette F | 1991 | Food Chemistry1991，39，9： | 1 |
| 12 | Determinants of active leisure for women with young children-an 'ethic of care'prevails显示文摘 | YVETTE D MILLER WENDY J BROWN | 2005 | Leisure Sci2005，27，： | 1 |
| 13 | Radiosensitization of cervical cancer cells via double- strand DNA break repair inhibition显示文摘 | Christa B Josh K Yvette D | 2008 | Gynecol Oncol2008，11，10： | 1 |
| 14 | The interpretation of inverse isochron diagrams in 40Ar/39Ar geochronology 显示文摘 | Yvette D K | 2002 | Earth and Planet Sci Lett2002，203，： | 1 |
| 15 | Too wet to exercise? Leaking urine as a barrier to physical activity in women显示文摘 | Wendy J Brown Yvette D Miller | 2001 | Journal of Science and Medicine in Sport2001，，4： | 1 |
| 16 | Oxygen free radical scavenger capacity in aqueous models of different procyanidins from grape seeds显示文摘 | Jorge M R D S Nicole D Yvette F | 1991 | Journal of Agricultural Food Chemistry1991，39，9： | 1 |
| 17 | Pedunculated atypical leiomyoma presenting as a hemoperitoneum显示文摘 | Yvette La Coursiere D Chin H G | 2005 | Journal of Gynecologic Surgery2005，21，1： | 1 |
| 18 | Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells显示文摘皮肤免疫系统的潜力很好被建立产生有免疫力的回答,并且皮肤活跃地作为一个种痘地点被利用。人的皮肤与专业化功能包含几个介绍抗原的房间子集。特别地,到到 CD8+ T 房间的跨礼品的外长的抗原的能力具有为对病毒或癌症的有效免疫疗法的设计的兴趣。这里,我们证明主要人的 Langerhans 房间(LC ) 对有能力跨礼品合成的长肽(SLP ) 到 CD8 + T 房间。另外,用对受体 langerin 的抗体的这 SLP 的修正,然而并非 dectin-1,进一步早通过使内在化的抗原的路由提高了 LC 的跨 presenting 能力到不太解朊的早内涵体抗原 1 + 内涵体。LC 的力量能进一步与像使用费的受体通过 LC 的激活被增加提高 CD8 +T 房间回答 3 ligand polyinosinic:polycytidylic 酸(pI : C ) 。总的来说,数据提供人的 LC 对在调停 langerin 的成为主观以后的跨礼品的抗原有能力的证据。而且,为到目标 LC 的抗原修正的潜力明确地为产生有效反肿瘤或抗病毒的细胞毒素的 T 淋巴细胞回答提供一个基本原理。 | Cynthia M Fehres Sanne Duinkerken Sven CM Bruijns Hakan Kalay Sandra J van Vliet Martino Ambrosini Tanja D de Gruijl Wendy WJ Unger Juan J Garcia-Vallejo Yvette van Kooyk | 2017 | Cellular & Molecular Immunology2017，14，4： | 0 |
| 19 | Symmetry-breaking Subharmonic Bifurcationsof Periodicaly Parameter-excited Systems显示文摘Symmetry-breakingSubharmonicBifurcationsofPeriodicalyParameter-excitedSystems11ThepaperwasreceivedonAug.30th,1996GuoweiHE1Lab... | Guowei HE 1 Laboratory for Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Science, Beijing, 10080, China 2 Service d’Astrophysique, CE-Saclay, L’orme des Merisiers 709, 91191, Gif sur Yvette, France E-mail: he@discovery | 1996 | Communications in Nonlinear Science and Numerical Simulation1996，1，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员