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| 1 | Fibroblast growth factor 21 as a possible endogenous factor inhibits apoptosis in cardiac endothelial cells显示文摘(FGF21 ) 背景成纤维细胞生长因素 21 是是为全身的葡萄糖和类脂化合物新陈代谢的一个重要内长的管理者的 FGF 超级家庭的一个新成员。这研究试图探索 FGF21 是否减少动脉粥样硬化患者损害并且作为独立保护 factor.Methods 阻止 endothelial 机能障碍现在的学习被设计调查氧化低的密度脂蛋白(ox-LDL ) 导致的 FGF21 层次的变化,并且 apoptosis 的变化由调整 FGF21 表示影响了。有教养的心脏的 microvascular endothelial 房间(CMEC ) 的 FGF21 mRNA 层次被真实 time-PCR 决定,在文化媒介的蛋白质集中被连接酶的 immunosorbent 试金检测。我们分析了与 ox-LDL 孵化的未经治疗的控制和 CMFC 的不同表示层次,并且 CMEC apoptosis 的变化由分泌物 FGF21 mRNA 铺平的 FGF21 levels.Results 的改进或抑制开始了,蛋白质是显著地,在 CMEC 的 upregulated 与 ox-LDL 孵化了。而且, 200 mol/L bezafibrate 增加的 FGF21 层次能减少 CMEC apoptosis ,并且由导致的 shRNA 禁止 FGF21 表示 apoptosis ( P 0.05 ) .Conclusions FGF21 可以是受伤目标织物的一个信号,并且可以在在动脉粥样硬化并且在停止冠的心疾病的开发的一个早阶段改进 endothelial 函数起生理的作用。 | Lv Yun LIU Jing-hua ZHANG Li-ke DU Jie ZENG Xiang-jun HAO Gang HUANG Ji ZHAO Dong-hui WANG Guo-zhong ZHANG Ying-chuan | 2010 | Chinese Medical Journal2010，，23： | 25 |
| 2 | Treatment and outcomes of 1041 pediatric patients with neuroblastoma who received multidisciplinary care in China显示文摘Importance:Neuroblastoma is the most common extracranial malignant solid tumor in children.Multidisciplinary care is critical to improving the survival of pediatric patients with neuroblastoma.Objective:To systematically summarize the clinical characteristics of children with neuroblastoma and evaluate their prognosis with multidisciplinary care provided in a single center.Methods:This retrospective study analyzed the clinical data of 1041 patients with neuroblastoma who were diagnosed,treated,and followed-up in the Hematology-Oncology Center of Beijing Children’s Hospital from 2007 to 2019.Results:The median age at diagnosis was 34 months;80.8%of the patients were younger than 5 years of age.Notably,243 patients(23.3%)were classified as low-risk,249 patients(23.9%)were classified as intermediate-risk,and 549(52.7%)were classified as high-risk.Furthermore,956 patients underwent surgical resections;986(94.7%)patients received chemotherapy;and 176 patients with high-risk neuroblastoma received hematopoietic stem cell transplantation.The 5-year event-free survival(EFS)rate was 91.3%and 5-year overall survival(OS)rate was 97.5%in low-risk group;in the intermediate-risk group,these rates were 85.1%and 96.7%,respectively,while they were 37.7%and 48.9%in the high-risk group(P<0.001 for both).The 5-year EFS and OS rates were significantly higher in patients diagnosed between 2015 and 2019 than in patients diagnosed between 2007 and 2014(P<0.001).In total,278 patients(26.7%)exhibited tumor relapse or progression;the median interval until relapse or progression was 14 months.Of the 233 patients who died,83%died of relapse or progression of neuroblastoma and 4.3%died of therapy-related complications.Interpretation:The 5-year OS rate was low in high-risk patients,compared with low-and intermediate-risk patients.Multidisciplinary care is critical for improvement of survival in pediatric patients with neuroblastoma.Additional treatment strategies should be sought to improve the prognosis of patients with high-risk neuroblastoma. | Yan Su Hong Qin Chenghao Chen Shengcai Wang Shihan Zhang Dawei Zhang Mei Jin Yun Peng Lejian He Xiaoman Wang Suyun Qian Maoquan Qin Ming Ge Fuquan Zhang Qi Zeng Huanmin Wang Xiaoli Ma Xin Ni | 2020 | Pediatric Investigation2020，4，3： | 16 |
| 3 | Congenital coronary artery fistulas: dual-source CT findings from consecutive 6624 patients with suspected or confirmed coronary artery disease显示文摘背景冠的动脉管( CAF )无意中经常是稀罕先天的反常与冠的动脉 disease.Clinical 在病人发现 CAF 的诊断是困难的由于无症状或特定的symptoms.Dual来源的缺乏计算了断层摄影术( DSCT )可能是为学习试图回顾地总结 CAF 的成像特征的 CAFs.The 的一个有用诊断工具在检测从的 48 个 CAF 病人在 DSCT 描出连续 6624 个病人与怀疑了或证实冠的动脉 | YUN Hong ZENG Meng-su YANG Shan JIN Hang YANG Xue | 2011 | Chinese Medical Journal2011，，24： | 15 |
| 4 | Weldability, microstructure and mechanical properties of laser-welded selective laser melted 304 stainless steel joints显示文摘Laser welding is a promising process for joining small components produced by selective laser melting (SLM) to fabricate the large-scale and complex-shaped parts. In the work, the morphology, microstructure, microhardness, tensile properties and corrosion resistance of the laser welded stress-relieved SLMed 304 stainless steel joints are investigated, as the different sections of stress-relieved SLMed 304 stainless steel are joined. Results show that the SLMed 304 stainless steel plates have a good laser weldability. The microstructure of laser-welded joints consists of the cellular dendrites in austenite matrix within columnar grains, exhibiting a coarser dendrite structure, lower microhardness (~220HV) and tensile properties (tensile strength of ~750 MPa, and area reduction of ~27.6%), but superior corrosion resistance to those of SLMed plates. The dendrite arm spacing of the joints varies from ~3.7μm in center zone, to ~5.0 (xm in fusion zone, to ~2.5 in epitaxial zone. The SLMed anisotropy shows a negligible effect on the microstructure and performance of the laser-welded joints. The laser welding along the building directions of the SLMed base plates can induce a slightly finer dendritic structure and higher tensile properties. | Jingjing Yang Yun Wang Fangzhi Li Wenpu Huang Guanyi Jing Zemin Wang Xiaoyan Zeng | 2019 | Journal of Materials Science & Technology2019，35，9： | 14 |
| 5 | The cloning of Dmc1 cDNAs and a comparative study of its expression in different ploidy cyprinid fishes显示文摘Dmc1 (disrupted meiotic cDNA) is a functionally specific gene, which was firstly discovered in yeast and then found to encode a protein required for homologous chromosome synapsis during the process of meiosis. In this investigation, we cloned the partial cDNAs of Dmc1 of diploid red crucian carp, Japanese crucian carp, common carp, triploid crucian carp and allotetraploid hybrids by using a pair of degenerate primers based on the conservative sequence of amino acids of the DMC1 protein in yeast, mouse and human. The full length cDNAs were then obtained by rapid amplification of cDNA ends (RACE). Our data showed that the full length cDNAs of Dmc1 in the three diploid fishes are all 1375 bp long, while it is 1383 bp long in triploids and 1379 bp long in allotetraploids. And despite of the variation in length, all the cDNAs encode a protein of 342 amino acids. A high homology of 97.3% of the DMC1 protein can be drawn by comparing the amino acid sequences in the three diploids, which is also of 86%, 86% and 95% similarity to human, mouse and zebrafish, respectively. A comparative study of the expression pattern of Dmc1 was carried out by RT-PCR using specific primers against the same se-quences of coding regions in different ploidy cyprinid fishes, from which it was showed that Dmc1 was expressed only in gonads of these five kinds of fishes. The expression pattern of Dmc1 in both ovaries and testes from different ploidy fishes within breeding season was also studied by Real-time PCR, and the results showed that the expression of this gene was greatly different among the three different ploidy fishes, which was the highest of triploid and lowest of allotetraploids. The histological sections data showed matured gonads of both diploid red crucian carp and allotetraploids in breeding season, although the latter demonstrated a higher maturation, and no gonadal maturation could be observed in triploids. In conclusion, we suggest that Dmc1 is specifically expressed in the period of meiosis in all the ploidy cyprinid fishes and directly related with the development of gonad in a manner of ploidy-independent way. And further, the high expression of Dmc1 in female triploids might be associ-ated with abnormal meiosis and sterility. | TAO Min, LIU ShaoJun, LONG Yu, ZENG Chen, LIU JiFang, LIU LiangGuo, ZHANG Chun, DUAN Wei & LIU Yun Key Laboratory of Protein Chemistry and Developmental Biology of State Education Ministry of China, College of Life Sciences, Hunan Normal University, Changsha 410081, China | 2008 | Science China(Life Sciences)2008，51，1： | 13 |
| 6 | Chinese Medicine Sequential Therapy Improves Pregnancy Outcomes after Surgery for Endometriosis-Associated Infertility: A Multicenter Randomized Double-blind Placebo Parallel Controlled Clinical Trial显示文摘Objective:To evaluate the efficacy and safety of Chinese medicine(CM)improving pregnancy outcomes after surgery for endometriosis-associated infertility.Methods:A multicenter,randomized,doubleblind placebo parallel controlled clinical trial was designed.A total of 202 patients who had laparoscopy for endometriosis-associated infertility with qi stagnation and blood stasis syndrome were included and randomly divided into the CM treatment group and placebo control group at a ratio of 1:1 using a central block randomization from May 2014 to September 2017,101 patients in each group.The two groups received continuous intervention at 1–5 days after surgery,for 6 menstrual cycles.Before ovulation,the CM group was treated Huoxue Xiaoyi Granule(活血消异颗粒);after ovulation,Bushen Zhuyun Granule(补肾助孕颗粒)was involved.The control group was treated with placebo.Transvaginal ultrasonography was performed every menstrual cycle during the treatment,and female hormone levels in the follicular and luteal phases were measured during the 1 st,3 rd and 6 th menstrual cycles.The analysis was continued until pregnancy.The primary outcomes were clinical pregnancy rate and pregnancy outcome,and the secondary outcomes were follicular development and endometrial receptivity.Safety evaluations were performed before and after treatment.Results:(1)Clinical pregnancy and live birth rates:the clinical pregnancy and live birth rates of the CM group were significantly higher than those of the placebo group[44.6%(45/101)vs.29.7%(30/101),34.7%(35/101)vs.20.8%(21/101),both P<0.05].(2)Follicle development:the incidence of dominant follicles,rate of cumulative cycle ovulation,and rate of cumulative cycle mature follicle ovulation were significantly higher in the CM group than those in the placebo group[93.8%(350/373)vs.89.5%(341/381),80.4%(275/342)vs.69.1%(253/366),65.8%(181/275)vs 56.1%(142/253),P<0.05 or P<0.01]).The incidence of cumulative cycle luteinized unruptured follicle syndrome was significantly lower in the CM group than in the placebo group[11.7%(40/342)vs.17.8%(65/366),P<0.05).(3)Endometrial receptivity:after treatment,both endometrial types and endometrial blood flow types in the CM group were mainly types A and B,while those in the placebo group were mainly types B and C,with a significant difference between the two groups(both P<0.05).(4)Adverse events:the incidence of adverse events between the two groups was not significantly different(P>0.05).Conclusion:Strategies for activating blood circulation-regulating Gan(Liver)-tonifying Shen(Kidney)sequential therapy can effectively improve the clinical pregnancy rate and live birth rate of endometriosis-associated infertility with qi stagnation and blood stasis after laparoscopy,improve follicular development,promote ovulation,improve endometrial receptivity,while being a safe treatment option.(Trial registration No.NCT02676713). | ZHAO Rui-hua LIU Yong LU Dan WU Ying WANG Xiao-yun LI Wei-li ZENG Cheng MENG Qing-wei LIAN Feng-mei ZHOU Jun SHI Yun SUN Wei-wei HAN Qian TANG Yi SHI Guang | 2020 | Chinese Journal of Integrative Medicine2020，26，2： | 13 |
| 7 | Pediatric reference intervals in China(PRINCE):design and rationale for a large,multicenter collaborative cross-sectional study显示文摘There is a lack of accurate pediatric reference intervals(RIs) in China, with most commonly used RIs established without consideration of the effect of age and gender. The Pediatric Reference Intervals in China(PRINCE) project aims to establish and verify pediatric RIs for 31 common laboratory measurands.The project will be a large, multicenter cross-sectional study:14,490 healthy children and adolescents aged up to 19 years will be surveyed by 10 children's hospitals and one pediatric department of a university hospital. To evaluate the feasibility and efficiency of the study methods, 602 children were surveyed in the pilot phase of the PRINCE study in April 2017: it found that some measurands were distinctly age dependent and that there were differences between values for males and females. The results of the pilot study affirmed the necessity of the PRINCE project for Chinese pediatrics. The pilot also indicated potential difficulties in the full survey, e.g., difficulties in recruiting children aged under 3 years and insufficient collection of blood samples from infants. The operation of the PRINCE project has been modified based on the findings in the pilot study toward improving the validity of the PRINCE project and promoting its openness and transparency. | Xin Ni Wenqi Song Xiaoxia Peng Ying Shen Yaguang Peng Qiliang Li Yan Wang Lixin Hu Yanying Cai Hong Shang Min Zhao Hong Jiang Yaoguo Huang Runqing Mu Wenxiang Chen Mingting Peng Chuanbao Zhang Jie Zeng Chenbin Li Hongling Yang Yongmei Jiang Jin Xu Guixia Li Hongbing Chen Yun Xiang Sancheng Cao Zhenxin Guo Dapeng Chen | 2018 | Science Bulletin2018，63，24： | 12 |
| 8 | Bedaquiline-containing regimens in patients with pulmonary multidrug-resistant tuberculosis in China:focus on the safety显示文摘Background:World Health Organization recommends countries introducing new drug and short treatment regimen for drug resistant tuberculosis(DR-TB)should develop and implement a system for active pharmacovigilance that allows for detection,reporting and management of adverse events.The aim of the study is to evaluate the frequency and severity of adverse events(AEs)of bedaquiline-containing regimen in a cohort of Chinese patients with multidrug-resistant(MDR)/extensively drug-resistant(XDR)-TB based on active drug safety monitoring(aDSM)system of New Drug Introduction and Protection Program(NDIP). | Jing-Tao Gao Juan Du Gui-Hui Wu Yi Pei Meng-Qiu Gao Leonardo Martinez Lin Fan Wei Chen Li Xie Yu Chen Hua Wang Long Jin Guo-Bao Li Pei-Lan Zong Yu Xiong Qian-Hong Wu Ming-Wu Li Xiao-Feng Yan Yan-Fang Miao Qing-Shan Cai Xin-Jie Li Da-Peng Bai Shu-Jun Geng Guo-Li Yang Pei-JunTang Yi Zeng Xiao-Hong Chen Tong-Xia Li Cui Cai Yun Zhou Ma Zhuo Jian-Yun Wang Wen-Long Guan Lin Xu Ji-Chan Shi Wei Shu Li-Li Cheng FeiTeng Yu-Jia Ning Shi-Heng Xie Yu-Xian Sun Li-Jie Zhang Yu-Hong Liu | 2021 | Infectious Diseases of Poverty2021，10，2： | 11 |
| 9 | Clinical and laboratory features,treatment,and outcomes of macrophage activation syndrome in 80 children:a multi-center study in China显示文摘Background Macrophage activation syndrome(MAS)is a major cause of morbidity and mortality in pediatric rheumatology.We aimed to further understand the clinical features,treatment,and outcome of MAS in China.Methods A multi-center cohort study was performed in seven hospitals in China from 2012 to 2018.Eighty patients with MAS were enrolled,including 53 cases with systemic juvenile idiopathic arthritis(SJIA-MAS),10 cases of Kawasaki disease(KD-MAS),and 17 cases of connective tissue disease(CTD-MAS).The clinical and laboratory data were collected before(pre-),at onset,and during full-blown stages of MAS.We compared the data among the SJIA-MAS,KD-MAS,and CTD-MAS subjects.Results 51.2%of patients developed MAS when the underlying disease was first diagnosed.In patients with SJIA,22.6%(12/53)were found to have hypotension before the onset of SJIA-MAS.These patients were also found to have significantly increased aspartate aminotransferase(AST)and lactate dehydrogenase(LDH),as well as decreased albumin(P<0.05),but no difference in alanine aminotransferase,ferdtin,and ratio of ferritin/erythrocyte sedimentation rate(ESR)at onset of MAS when compared to pre-MAS stages of the disease.In addition,ferritin and ratio of ferritin/ESR were significantly elevated in patients at full-blown stages of SJIA-MAS compared to pre-MAS stage.Significantly increased ferritin and ratio of ferritin/ESR were also observed in patients with SJIA compared to in KD and CTD.Receiver-operating characteristic analysis showed that 12,217.5μg/L of ferritin and 267.5 of ferritin/ESR ratio had sensitivity(80.0%and 90.5%)and specificity(88.2%and 86.7%),respectively,for predicting full-blown SJIA-MAS.The majority of the patients received corticosteroids(79/80),while biologic agents were used in 12.5%(10/80)of cases.Tocilizumab was the most commonly selected biologic agent.The overall mortality rate was 7.5%.Conclusions About half of MAS occurred when the underlying autoimmune diseases(SJIA,KD,and CTD)were first diagnosed.Hypotension could be an important manifestation before MAS diagnosis.Decreased albumin and increased AST,LDH,ferritin,and ratio of ferritin/ESR could predict the onset or full blown of MAS in patient with SJIA. | Li-Xia Zou Yun Zhu Li Sun Hui-Hui Ma Si-Rui Yang Hua-Song Zeng Ji-Hong Xiao Hai-Guo Yu Li Guo Yi-Ping Xu Mei-Ping Lu | 2020 | World Journal of Pediatrics2020，16，1： | 11 |
| 10 | Inhibitory effect of acetylshikonin on human gastric carcinoma cell line SGC-7901 in vitro and in vivo显示文摘AIM:To investigate the inhibitory effect of acetylshikonin on human gastric carcinoma cell line SGC-7901 and its mechanism. METHODS:MTT assay was used to assess the inhibitory effect of acetylshikonin on proliferation of SGC-7901 cells.Apopt osis-inducing effect was determined by flow cytometry and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling with Hoechst staining.Expression of mRNA and protein in Bcl-2 and Bax was analyzed by reverse transcription-polymerase chain reaction and Western blot.Antitumor effect of acetylshikonin on a mouse SGC-7901 model was also determined. RESULTS:Forty-eight hours after treatment with acetylshikonin,MTT assay showed that acetylshikonin inhibited the proliferation of SGC-7901 cells in a dose-dependent manner.The half maximal inhibitory concentration of acetylshikonin to SGC-7901 cells was 0.428±0.07 mg/L.Cell shrinkage,nuclear pyknosis and chromatin condensation,which are the characteristics of cell apoptosis,were observed in treated SGC-7901 cells and the percentage of apoptosis increased in a dose-dependent manner.Acetylshikonin downregulated the expression of Bcl-2 and up-regulated the expression of Bax in the treated SGC-7901 cells compared with the controls.The experiment in vivo showed that 0.5,1,and 2 mg/kg of acetylshikonin significantly inhibited the growth of tumor in the mouse SGC-7901 model,with an inhibitory rate of 25.00%-55.76%. CONCLUSION:Acetylshikonin inhibits the growth of SGC-7901 cells in vitro and in vivo by inducing cell apoptosis. | Yun Zeng Gang Liu Li-Ming Zhou | 2009 | World Journal of Gastroenterology2009，15，15： | 10 |
| 11 | Induction of gynogenesis in red crucian carp using spermatozoa of blunt snout bream显示文摘Gynogenetic 双在红鲫鱼鲤鱼(RCC )(Carassius auratus 红变化) 被导致从钝猪嘴鲷(B)(Megalabrama amblycephala ) 或从镜子鲤鱼(C) 的鸡蛋使用紫外照耀精子(Cyprinus carpio。L) 。精子被适当紫外剂量遗传上使失去活性,然后母亲的 DNA 在 0-4 ° C 与冷吃惊被复制。当使用 B 的精子时,起初喂的授精率,孵化的率和幸存是 52.6 ± 3.0 %, 23.6 ± 4.1 %和 15.7 ± 3.4 %分别地,并且起初喂的幸存比那显著地高( 11.3 ± 2.2%)当使用 C 的精子时( Cypripnus carpio 。L) 。根据词法特征,染色体数字和 gonadal 开发的度, gynogenetic RCC 能与 RCC ♀
的控制混血儿被区分开来B♂ 。有红身体颜色, 100 个染色体和正常 gonadal 开发的个人是 syccessful gyogenetic RCC,当有 124 或 148 个染色体和推迟的 gonadal 开发的个人是混血儿时(RCC B ) 。三倍性的混血儿(RCC B )(2 岁) 是无菌的,但是 tetraploid 混血儿(RCC B ) 是二的性成熟的年龄。在现在的学习,与 C 的精子相比, B 的 spermatoxoa 的优点作为激活来源是那能增加起初 gynogentic 个人和 simplfy 喂 gynogenetic 的证实的幸存地位,它建议 B 的精子是为在鲫鱼鲤鱼导致 gynogenesis 的有效激活来源。 | SUN Yuandong TAO Min LIU Shaojun ZHANG Chun DUAN Wei SHEN Jiamin WANG Jing ZENG Chen LONG Yu LIU Yun | 2007 | Progress in Natural Science:Materials International2007，17，2： | 10 |
| 12 | Risk Factors and Pregnancy Outcomes: Complete versus Incomplete Placenta Previa in Mid-pregnancy显示文摘 | Yun FENG Xue-yin LI Juan XIAO Wei LI Jing LIU Xue ZENG Xi CHEN Kai-yue CHEN Lei FAN Qing-ling KANG Su-hua CHEN | 2018 | Current Medical Science2018，38，4： | 8 |
| 13 | Interaction between en- dogenous nitric oxide and carbon monoxide in the pathogenesis of hypoxic pulmonary hypertension显示文摘The aim of the study was to investigate the in-teraction between nitric oxygenase (NOS)/ nitric oxide (NO) and heme oxygenase (HO)/ carbon monoxide (CO) system in the pathogenesis of hypoxic pulmonary hypertension. On a rat model of hypoxic pulmonary hypertension, the pulmo-nary artery pressure was measured, and NO formation and expression of NOS in pulmonary tissues were examined after treatment with ZnPP-IX, an HO-1 inhibitor. The pulmonary artery pressure, CO formation and expression of HO-1 in pulmonary tissues were examined after treatment with L-NAME, a NOS inhibitor. We found that pulmonary hy-pertension developed after 2-week hypoxia, while the con-centration of NO in the pulmonary tissue homogenates and the expression of NOS in intrapulmonary artery endothelial cells decreased markedly. ZnPP-IX worsened pulmonary hypertension of hypoxic rats. However, it increased endoge-nous production of NO and the expression of NOS obviously. The concentration of CO in the pulmonary tissue homoge-nates and the expression of HO-1 in intrapulmonary artery smooth muscle cells increased markedly with hypoxic pul-monary hypertension. L-NAME worsened pulmonary hy-pertension of hypoxic rats, but inhibited CO formation and HO-1 expression (P < 0.01). The results of this study sug-gested that endogenous NOS/NO and HO/CO systems might interact with each other and therefore play an important regulating role in hypoxic pulmonary hypertension. | SHI Yun, DU Junbao, GUO Zhiliang, ZENG Chaomei & TANG Chaoshu Department of Pediatrics, the First Hospital, Peking University, Beijing 100034, China Correspondence should be addressed to Du Junbao (e-mail: junbaodu@ ht.rol.cn) | 2003 | Chinese Science Bulletin2003，48，1： | 8 |
| 14 | Psychophysiological Effects of Bamboo Plants on Adults显示文摘The present study was conducted to clarify the psychophysiological relaxation effects of viewing bamboo on university students. Forty healthy Chinese participants enrolled in this study to clarify the psychophysiological relaxation effects of viewing bamboo. The effects of visual stimulation using a pot both with and without a bamboo were recorded by measuring the student's blood pressure, EEG and STAI. We observed that viewing bamboo plants resulted in significantly lower systolic(female, P < 0.001; male, P < 0.001; P < 0.05) and diastolic(female,P < 0.001; male, P < 0.001; P < 0.05) blood pressures, but no changes in the pulse rate(female, P = 0.09; male, P = 0.07; P > 0.05) were observed. The results of the EEG analysis indicated brainwave variation(all P < 0.05) and lower anxiety scores(P < 0.01) after 3 min of viewing bamboo compared with the control. These findings indicate that visual stimulation with bamboo plants induced psychophysiological relaxation effects on adults. | Ahmad Hassan CHEN Qi Bing JIANG Tao LYU Bing Yang LI Nian LI Shu SHANGGUAN Zi Yue LI Yun Ting JUN Zhou Li LUO Qian CHEN Xin Yi WANG Yi Yan ZENG Cheng Cheng YANG Jun Muhammad Sohaib Tahir | 2017 | Biomedical and Environmental Sciences2017，30，11： | 8 |
| 15 | Microphysical Characteristics of Precipitation during Pre-monsoon,Monsoon, and Post-monsoon Periods over the South China Sea显示文摘Raindrop size distribution (RSD) characteristics over the South China Sea (SCS) are examined with onboard Parsivel disdrometer measurements collected during marine surveys from 2012 to 2016. The observed rainfall is divided into premonsoon, monsoon, and post-monsoon periods based on the different large-scale circumstances. In addition to disdrometer data, sounding observation, FY-2E satellite, SPRINTARS (Spectral Radiation-Transport Model for Aerosol Species), and NCEP reanalysis datasets are used to illustrate the dynamical and microphysical characteristics associated with the rainfall in different periods. Significant variations have been observed in respect of raindrops among the three periods. Intercomparison reveals that small drops (D < 1 mm) are prevalent during pre-monsoon precipitation, whereas medium drops (1?3 mm) are predominant in monsoon precipitation. Overall, the post-monsoon precipitation is characterized by the least concentration of raindrops among the three periods. But, several large raindrops could also occur due to severe convective precipitation events in this period. Classification of the precipitation into stratiform and convective regimes shows that the lg(Nw) value of convective rainfall is the largest (smallest) in the pre-monsoon (post-monsoon) period, whereas the Dm value is the smallest (largest) in the pre-monsoon (post-monsoon) period. An inversion relationship between the coefficient A and the exponential b of the Z?R relationships for precipitation during the three periods is found. Empirical relations between Dm and the radar reflectivity factors at Ku and Ka bands are also derived to improve the rainfall retrieval algorithms over the SCS. Furthermore, the possible causative mechanisms for the significant RSD variability in different periods are also discussed with respect to warm and cold rain processes, raindrop evaporation, convective activities, and other meteorological factors. | Qingwei ZENG Yun ZHANG Hengchi LEI Yanqiong XIE Taichang GAO Lifeng ZHANG Chunming WANG Yanbin HUANG | 2019 | Advances in Atmospheric Sciences2019，36，10： | 7 |
| 16 | Genomic variation in the hybrids of white crucian carp and red crucian carp: evidence from ribosomal DNA显示文摘In this study, we conducted a cross of white crucian carp(♀)×red crucian carp(♂)(WR), and characterized the morphology, reproduction and genetics of the progeny. Different from parents, WR with the gray color showed the hybrid morphological traits of both parents. WR possessed normal gonads producing mature eggs or sperm, and exhibited high fertilization rate(90.2%) and high hatchery rate(80.5%), which contributed to produce and enlarge the population. WR with the same DNA content as parents was a diploid fish with 100 chromosomes(2n=100). Amplified ITS of 45 S r DNA, in WR the sequences consisting of 884 bp bases of the entire ITS-1 region, 5.8 S region, and entire ITS-2 region. The sequences showed high similarity between WR and its parents and leaned towards male inheritance. In WR, NTS of 5S r DNA consisted of three length types with total 654 bp bases. From sequence analysis of NTS, WR shared 94.2% and 95.1% similarities with their female and male parent, respectively. Sequence analysis of ITS and NTS revealed that there existed recombination and variation in the hybrid progeny, which was the genetic base for adaptation and speciation. In conclusion, we obtained WR from hybridization and it exhibited hybrid traits in morphology and variation in genetic composition showing essential difference with its parents. The obtainment of WR has important significance in fish genetic breeding. | WANG Jing XIAO Jun ZENG Ming XU Kang TAO Min ZHANG Chun DUAN Wei LIU WenBin LUO KaiKun LIU Yun LIU ShaoJun | 2015 | Science China(Life Sciences)2015，58，6： | 7 |
| 17 | Fe/MCM-41 as a promising heterogeneous catalyst for ozonation of p-chlorobenzoic acid in aqueous solution显示文摘Mesoporous MCM-41 和 Fe 装载了 MCM-41 (Fe/MCM-41 ) ,它被一个热水的方法和一个蘸的方法成功地分别地准备,在水的答案为 p-chlorobenzoic 酸(p-CBA ) 的 ozonation 作为异构的催化剂被使用。MCM-41 和 Fe/MCM-41 被 XRD,英尺红外和弥漫的反射 UVvis (DR-UVvis ) 技术描绘。MCM-41 或 Fe/MCM-41 的存在改进 p-CBA 和全部的器官的碳(TOC ) 与 ozonation 相比的移动效率独自一个。在试验性的条件下面, Fe/MCM-41/O3 过程的 TOC 移动率在 60 min 氧化时间是超过 63.5% , 44.5% 使用 MCM-41 作为催化剂,仅仅 37.7% 与 ozonation 独自一个。在 Fe/MCM-41/O3 过程的 turt-butanol (TBA ) 的存在显示 p-CBA 的氧化机制发生经由哦在液体体积。并且 Fe/MCM-41 是有希望的催化剂。 | Rui Huan Huang Jie Liu Lai Sheng Li Qiu Yun Zhang Li Xuan Zeng Ping Lu | 2011 | Chinese Chemical Letters2011，22，6： | 6 |
| 18 | Removal of Nitrogen, Phosphorus, and Organic Pollutants From Water Using Seeding Type Immobilized Microorganisms显示文摘Objective To study the possibility of removing nitrogen, phosphorus, and organic pollutants using seeding type immobilized microorganisms. Methods Lakes P and M in Wuhan were chosen as the objects to study the removal of nitrogen, phosphorus, and organic pollutants with the seeding type immobilized microorganisms. Correlations between the quantity of heterotrophic bacteria and the total nitrogen (TN), total phosphorus (TP), and total organic carbon (TOC) in the two lakes were studied. The dominant bacteria were detected, inoculated to the sludge and acclimated by increasing nitrogen, phosphorus and decreasing carbon source in an intermittent, time-controlled and fixed-quantity way. The bacteria were then used to prepare the seeding type immobilized microorganisms, selecting diatomite as the adsorbent carrier. The ability and influence factors of removing nitrogen, phosphorus, and organic pollutant from water samples by the seeding type immobilized microorganisms were studied. Results The coefficients of the heterotrophic bacterial quantity correlated with TOC, TP, and TN were 0.9143, 0.8229, 0.7954 in Lake P and 0.9168, 0.7187, 0.6022 in Lake M. Ten strains of dominant heterotrophic bacteria belonging to Pseudomonas, Coccus, Aeromonas, Bacillus, and Enterobateriaceae, separately, were isolated. The appropriate conditions for the seeding type immobilized microorgansims in purifying the water sample were exposure time=24 h, pH=7.0-8.0, and quantity of the immobilized microorganisms=0.75-1g/50 mL. The removal rates of TOC, TP, and TN under the above conditions were 80.2%, 81.6%, and 86.8%, respectively. Conclusion The amount of heterotrophic bacteria in the two lakes was correlated with TOC, TP, and TN. These bacteria could be acclimatized and prepared for the immobilized microorganisms which could effectively remove nitrogen, phosphorus, and mixed organic pollutants in the water sample. | LIN WANG LI-JING HUANG LUO-JIA YUN FEI TANG JING-HUI ZHAO YAN-QUN LIU XIN ZENG QI-FANG LUO | 2008 | Biomedical and Environmental Sciences2008，21，2： | 6 |
| 19 | Preparation of phosphorus-modified PITQ-13 catalysts and their performance in 1-butene catalytic cracking显示文摘A series of phosphorus-modified PITQ-13 catalysts was prepared by wet impregnation of NH4H2PO4solution into an HITQ-13 parent. The catalysts were characterized using XRD, N2adsorption, MAS NMR and NH3-TPD. Their catalytic performance in 1-butene catalytic cracking was evaluated in a fixed fluidized bed reactor. The results showed that the crystallinity, surface area and pore volume of P-modified PITQ-13catalysts decreased with the increasing amounts of P. The number of weak acid sites increased, whereas that of strong acidity decreased. The selectivity to propylene in 1-butene cracking reactions increased because of the decrease in strong acidity. The yield of propylene achieved41.6% over PITQ-13-2 catalyst with a P content of 1.0 wt%, which was 5.1% greater than that achieved over HITQ-13 catalyst. | Penghui Zeng Yun Liang Shengfu Ji Baojian Shen Honghai Liu Baojie Wang Hongjuan Zhao Mingfu Li | 2014 | Journal of Energy Chemistry2014，23，2： | 6 |
| 20 | LLC Resonant Converter Topologies and Industrial Applications-A Review显示文摘Owing to the advantages of high efficiency,high energy density,electrical isolation,low electromagnetic interference(EMI)and harmonic pollution,magnetic integration,wide output ranges,low voltage stress,and high operation frequency,the LLC resonant converters are widely used in various sectors of the electronics-based industries.The history and development of the LLC resonant converters are presented,their advantages are analyzed,three of the most popular LLC resonant converter topologies with detailed assessments of their strengths and drawbacks are elaborated.Furthermore,an important piece of research on the industrial applications of the LLC resonant converters is conducted,mainly including electric vehicle(EV)charging,photovoltaic systems,and light emitting diode(LED)lighting drivers and liquid crystal display(LCD)TV power supplies.Finally,the future evolution of the LLC resonant converter technology is discussed. | Junming Zeng Guidong Zhang Samson Shenglong Yu Bo Zhang Yun Zhang | 2020 | Chinese Journal of Electrical Engineering2020，6，3： | 6 |
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