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| 1 | Glacier retreat and its effect on stream flow in the source region of the Yangtze River显示文摘在冰河上在气候变化的效果上正在种担心融化并且水文学。在这篇文章,我们在长江的来源区域使用了二自然的小规模的盆, Tuotuo 河和 Buqu 河,中国,到表演,冰河的影响融化在溪流流动上。在在 1970, 1992 和 2009 的冰河和冰体积的程度的变化用遥感图象被评估。在一样的时间间隔上的冰河表面区域的变化用 Landsat TM/ETM+ 形象通过冰河轮廓和位置的描述被估计。在 2009,冰河表面区域分别地在 Tuotuo 河和 Baqu 河盆由 1970 价值中的 20.83% 个和 34.81% 减少了。在每盆的全部的 meltwater 供应被估计是 2.56 ?? | WU Shanshan YAO Zhijun HUANG Heqing LIU Zhaofei CHEN Yuansheng | 2013 | Journal of Geographical Sciences2013，23，5： | 13 |
| 2 | Spatial-temporal patterns of major ion chemistry and its controlling factors in the Manasarovar Basin, Tibet显示文摘因为它的唯一的地理环境,在南部的西藏的 Manasarovar 盆,在佛教被认为一块神圣陆地,引起了国际学术注意。在这研究,基于 43 水里的主要离子集中的实际大小,样品在年期间收集了 2005 和 2012,我们全身地在湖和 inflowing 河分析了水化学和它的控制因素的空间时间的模式。结果表明在 Manasarovar 盆的水是稍微碱的,与在 7.47.9 之间变化的 pH。分别地,在湖和河水的全部的溶解固体(TDS ) 的数量是约 325.4 和 88.7 mg/l 在西藏的高原在大多数表面水里比那降低。因为成为蒸气的结晶化的长期的效果,在湖, Na <啜class=“ a-plus-plus ”>+和 HCO <潜水艇class=“ a-plus-plus ”> 3 <啜class=“ a-plus-plus ”>有最高的集中,为全部的阳离子和阴离子内容中的46.8%个和86.8%的财务。在 inflowing 河里,然而,主导的离子是 Ca < 啜 class= “ a-plus-plus ” >2+ 和 HCO < 潜水艇 class= “ a-plus-plus ” > 3 < 啜 class= “ a-plus-plus ” > 为全部的阳离子和阴离子内容中的 59.6% 个和 75.4% 的 , 财务。水交换为如此的一个大湖是不够的,导致离子作文的一个显著空间变化。分别地湖,离子集中在湖的另外的方面上在比那显著地高的北方方面上有几条大 inflowing 河,与 468.9 和 254.9 mg/l 的 TDS。在复杂环境的影响下面,在水化学的空间变化在河里是甚至更重要的,与展出一个更高离子的内容的 upstreams。臼齿的比率在之间( Ca <啜class=“ a-plus-plus ”>2+ +Mg2+)并且( Na <啜class=“ a-plus-plus ”>+ +K+)比 1.0 高得多,表明水里的离子的主要来源是捱过的碳酸盐。尽管自然过程例如捱过的摇滚乐,是在盆控制主要离子化学的主要因素,在未来,我们需要对人为的影响给予更多的注意。 | YAO Zhijun WANG Rui LIU Zhaofei WU Shanshan JIANG Liguang | 2015 | Journal of Geographical Sciences2015，25，6： | 11 |
| 3 | Time-dependent safety of lining structures of circular tunnels in weak rock strata显示文摘Following tunnel excavation and lining completion,fractured surrounding rock deforms gradually over time;this results in a time-dependent evolution of the pressure applied to the lining structure by the surrounding rock.Thus,the safety of the tunnel lining in weak strata is strongly correlated with time.In this study,we developed an analytical method for determining the time-dependent pressure in the surrounding rock and lining structure of a circular tunnel under a hydrostatic stress field.Under the proposed method,the stress–strain relationship of the fractured surrounding rock is assumed to conform to that of the Burgers viscoelastic component,and the lining structure is assumed to be an elastomer.Based on these assumptions,the viscoelastic deformation of the surrounding rock,the elastic deformation of the lining structure,and the coordinated deformation between the surrounding rock and lining structure were derived.The proposed analytical method,which employs a time-dependent safety coefficient,was subsequently used to estimate the durability of the lining structure of the Foling Tunnel in China.The derived attenuation curve of the safety coefficient with respect to time can assist engineers in predicting the remaining viable life of the lining structure.Unlike existing analytical methods,the method derived in this study considers the time dependency of the interaction between the surrounding rock and tunnel lining;hence,it is more suitable for the evaluation of lining lifetime. | Baoguo Liu Yu Song Zhaofei Chu | 2022 | International Journal of Mining Science and Technology2022，32，2： | 7 |
| 4 | Real-time rock mass condition prediction with TBM tunneling big data using a novel rock-machine mutual feedback perception method显示文摘Real-time perception of rock mass information is of great importance to efficient tunneling and hazard prevention in tunnel boring machines(TBMs).In this study,a TBM-rock mutual feedback perception method based on data mining(DM) is proposed,which takes 10 tunneling parameters related to surrounding rock conditions as input features.For implementation,first,the database of TBM tunneling parameters was established,in which 10,807 tunneling cycles from the Songhua River water conveyance tunnel were accommodated.Then,the spectral clustering(SC) algorithm based on graph theory was introduced to cluster the TBM tunneling data.According to the clustering results and rock mass boreability index,the rock mass conditions were classified into four classes,and the reasonable distribution intervals of the main tunneling parameters corresponding to each class were presented.Meanwhile,based on the deep neural network(DNN),the real-time prediction model regarding different rock conditions was established.Finally,the rationality and adaptability of the proposed method were validated via analyzing the tunneling specific energy,feature importance,and training dataset size.The proposed TBM-rock mutual feedback perception method enables the automatic identification of rock mass conditions and the dynamic adjustment of tunneling parameters during TBM driving.Furthermore,in terms of the prediction performance,the method can predict the rock mass conditions ahead of the tunnel face in real time more accurately than the traditional machine learning prediction methods. | Zhijun Wu Rulei Wei Zhaofei Chu Quansheng Liu | 2021 | Journal of Rock Mechanics and Geotechnical Engineering2021，13，6： | 6 |
| 5 | Effects of extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) on excisional wound healing in a rat's model显示文摘OBJEVTIVE: To investigate the effects of extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) on the excisional wound healing in a rat's model.METHODS: Rats were performed a surgical lesion with a 2.0 cm resected tissue in the dorsal fascia.Following, animals were randomly divided into model group, YNB group and APE group those were respectively treated with saline, 1 mg/mL of Yunnan Baiyao and 1 mg/mL of Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) extracts. Wound contractions in days 0, 3, 7, 14 and 21 were calculated by an image analyzer. Histological analysis was analyzed using hematoxilin and eosin.Levels of tumor necrosis factor-2(IL-2), IL-4, IL-10, transformαin(TNF-g growα), interleukinth factor-1(TGF-nd basic fibroblast growth factor(bFββ1) a-GF) were determined by real-time quantitative PCR.RESULTS: Compared with that of YNB group and APE gtoup, the skin of rats showed poor re-modeling and re-epithelization characterized by a significant decrease of neovascularization, epithelialization and fibroblast in the model group. In the APE group, levels of TNF-α-and IL-2 were significantly down-regulated and IL4 and IL-10 significantly upregulated in contrasted with that of model group.In addition, levels of TGF-roup were significantly iβ1 and bFGF in the APE gnduced compared with that of model group.CONCLUSION: The results suggest that the extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) promote wound healing in the rats, which is associated with enhancing antiinflammatory ability and inducing fibroblast formation. | Xia Xichao Ma Yuhong Wang Fuan Zheng Xinhua Liu Yang Zhang Junfeng Cui Juan Shi Bingqin Li Hongwen Liu Rongzhi Zhang Yaping Cheng Zhaofei Han Xiaolong | 2019 | Journal of Traditional Chinese Medicine2019，39，1： | 4 |
| 6 | Effects of Normalized Difference Vegetation Index and Related Wavebands′ Characteristics on Detecting Spatial Heterogeneity Using Variogram-based Analysis显示文摘Spatial heterogeneity is widely used in diverse applications, such as recognizing ecological process, guiding ecological restoration, managing land use, etc. Many researches have focused on the inherent scale multiplicity of spatial heterogeneity by using various environmental variables. How these variables affect their corresponding spatial heterogeneities, however, have received little attention. In this paper, we examined the effects of characteristics of normalized difference vegetation index (NDVI) and its related bands variable images, namely red and near infrared (NIR), on their corresponding spatial heterogeneity detection based on variogram models. In a coastal wetland region, two groups of study sites with distinct fractal vegetation cover were tested and analyzed. The results show that: 1) in high fractal vegetation cover (H-FVC) area, NDVI and NIR variables display a similar ability in detecting the spatial heterogeneity caused by vegetation growing status structure; 2) in low fractal vegetation cover (L-FVC) area, the NIR and red variables outperform NDVI in the survey of soil spatial heterogeneity; and 3) generally, NIR variable is ubiquitously applicable for vegetation spatial heterogeneity investigation in different fractal vegetation covers. Moreover, as variable selection for remote sensing applications should fully take the characteristics of variables and the study object into account, the proposed variogram analysis method can make the variable selection objectively and scientifically, especially in studies related to spatial heterogeneity using remotely sensed data. | WEN Zhaofei ZHANG Ce ZHANG Shuqing DING Changhong LIU Chunyue PAN Xin LI Huapeng SUN Yan | 2012 | Chinese Geographical Science2012，22，2： | 4 |
| 7 | ^(99m)Tc-3P_4 -RGD_2 radiotracers for SPECT/CT of esophageal tumor显示文摘In recent years,several RGD(Arg-Gly-Asp)-based radiotracers have already been successfully tested in human for the visualization of integrin αvβ3,demonstrating its feasibility in tumor diagnosis.In this paper,we evaluated the 99mTc-3P4-RGD2 single photon emission computed tomography/computerized tomography(SPECT/CT)in patients suffering from space occupying disease of esophagus.40 patients(34 males and 6 female;mean age: 58.3 years) with a suspected space occupying lesion of esophagus were included,thus finally obtaining their definite pathologic diagnosis(malignant,n=32;benign,n=8).All patients underwent endoscopic,barium esophagography and SPECT/CT imaging preoperatively.The chest SPECT was performed at 4 h after administration of99mTc-3P4-RGD2 with a dose of 939±118 MBq.The diagnosis precision,sensitivity and specificity among these methods were compared.The relationship between radioactive uptake and clinical pathological stage of esophageal carcinoma was discussed by calculating the tumor to normal esophagus(T/N).Meanwhile,the integrin αvβ3 expression was assessed immunohistochemically in postoperative esophageal tissues.31 patients were diagnosed as esophageal carcinoma;and 1,leiomyosarcoma;and 6.leimyoma;and 2,esophageal tuberculosis.The accuracy,sensitivity and specificity of barium esophagography,endoscopic and SPECT/CT imaging are 92.5/93.8/87.5%,97.5/96.9/100%,and 90/90.6/87.5%,respectively.Abnormal accumulation of radiotracer in 29 malignant lesions is observed.The SPECT/CT imaging displayed the region of radioactive uptake and lesions matched extremely with the T/N ratio from 1.31 to 2.79(mean 2.04).A case with pulmonary metastases and a case with mediastinal lymph node metastases were found which were missed by barium esophagography and endoscopic.The99mTc-3P4-RGD2 uptake of the esophageal carcinoma masses had no relevance to the tumor pathologic classification(P>0.05).There was a significant positive correlation between T/N ratio and positive cell percentage of integrin αvβ3(r=0.976),demonstrating the certain clinical potential in the diagnosis of esophageal carcinoma. | GAO Shi MA Qingjie WEN Qiang JIA Bing LIU Zhaofei CHEN Zuowei ZHANG Haishan LI Dandan | 2013 | Nuclear Science and Techniques2013，24，4： | 3 |
| 8 | In situ prepared Al-Si alloy matrix composites reinforced by γ-Al_2O_3p显示文摘A γ-Al2O3 particles reinforced Al-Si alloy matrix composite was fabricated by adding NH4Al(SO4)2 to molten aluminum alloy. TEM observation shows that in-situ γ-Al2O3 particles are generally spherical and uniformly distributed in the matrix. The results of dry sliding wear tests show that the wear resistance of the composites increases with increasing mass fraction, and the volume loss is considerably lesser than that of the matrix and is lesser than that of the composites by adding γ-Al2O3 particles directly. | Lan Jiang Bo Jiang Zhaofei Wang Yue Wang Ji Liu | 2007 | Journal of University of Science and Technology Beijing2007，14，3： | 1 |
| 9 | 99mTc-labeled RGD-BBN peptide for small-animal SPECT/CT of lung carcinoma显示文摘 | Liu Zhaofei Huang Jinming Dong Chengyan | 2012 | Molecular Pharma- ceutics2012，9，5： | 1 |
| 10 | Trend of major hydroclimatic variables in the Tarim River basin during the past 50 years显示文摘 | XU Zongxue Liu Zhaofei Fu Guobin | 2010 | Journal of Arid Environments2010，74，2： | 1 |
| 11 | Trends of major hydroclimatic variables in the Tarim River basin during the past 50 years 显示文摘 | Xu Zongxue Liu Zhaofei | 2010 | Journal of Arid Environments2010，，74： | 1 |
| 12 | Statistical estimation of the impacts of glaciers and climate change on river runoff in the headwaters of the Yangtze River显示文摘 | Zhijun Yao Zhaofei Liu Heqing Huang Gaohuan Liu Shanshan Wu | 2013 | Quaternary International2013，，： | 1 |
| 13 | Resveratrol inhibits high glucose induced collagen upregulation in cardiac fibroblasts through regulating TGF-β1–Smad3 signaling pathway显示文摘 | Junhui Liu Xiaozhen Zhuo Weimin Liu Zhaofei Wan Xiao Liang Shanshan Gao Zuyi Yuan Yue Wu | 2015 | Chemico-Biological Interactions2015，，： | 1 |
| 14 | Trends of major hydroclimatic variables in the Tarim River basin during the past 50 years显示文摘 | Xu Zongxue Liu Zhaofei Fu Guobin | 2010 | Journal of Arid Environments2010，74，： | 1 |
| 15 | Comparison of surface water chemistry and weathering effects of two lake basins in the Changtang Nature Reserve,China显示文摘The geochemistry of natural waters in the Changtang Nature Reserve,northern Tibet,can help us understand the geology of catchments,and provide additional insight in surface processes that influence water chemistry such as rock weathering on the Qinghai–Tibet Plateau.However,severe natural conditions are responsible for a lack of scientific data for this area.This study represents the first investigation of the chemical composition of surface waters and weathering effects in two lake basins in the reserve(Lake Dogaicoring Qiangco and Lake Longwei Co).The results indicate that total dissolved solids(TDS)in the two lakes are significantly higher than in other gauged lakes on the Qinghai–Tibet Plateau,reaching 20–40 g/L,and that TDS of the tectonic lake(Lake Dogaicoring Qiangco)is significantly higher than that of the barrier lake(Lake Longwei Co).Na+and Cl-are the dominant ions in the lake waters as well as in the glacier-fed lake inflows,with chemical compositions mainly affected by halite weathering.In contrast,ion contents of inflowing rivers fed by nearby runoff are lower and concentrations of dominant ions are not significant.Evaporite,silicate,and carbonate weathering has relatively equal effects on these rivers.Due to their limited scope,small streams near the lakes are less affected by carbonate than by silicate weathering. | Rui Wang Zhaofei Liu Liguang Jiang Zhijun Yao Junbo Wang Jianting Ju | 2016 | Journal of Environmental Sciences2016，28，3： | 1 |
| 16 | Effect of statins use on the prevention of venous thromboembolism: a meta-analysis显示文摘Objective: To estimate the effect of statins use on the prevention of venous thromboembolism (VTE). Methods: We systematically searched MEDLINE (1980-June 2012), EMBASE (1980-June 2012), Google Scholar, Cochrane Library, and ISI Web of Science, manually reviewed references, and contacted experts. Case-control studies and cohort studies that compared any dose of statin with no statin or placebo are included. Data extraction and study quality evaluation were independently conducted in duplicate. Results: 12 studies including four cohort studies and eight case-control studies were identified and eligible for meta-analysis. Upon meta-analysis, statin use was associated with a statistically significant reduction in the odds of developing VTE (OR 0.91, 95% CI 0.86-0.96). Conclusion: This meta-analysis of current and available literature suggests that statins can reduce patient's risk of developing VTE. Due to the limitations of observational study, this conclusion should be considered with caution, and additionally, specifical well-designed trials are needed. | Zhang Zaiwei Tian Hongyan Pan Junqiang Zhao Yaling Wan Zhaofei Zhang Junbo Ma Qiang Tian Hua Han Junli Liu Ya Deng Jizhao | 2012 | Journal of Medical Colleges of PLA(China)2012，27，5： | 1 |
| 17 | Peak slip and load-slip realatlonshlp o! headed stud connectors 显示文摘 | LIN Zhaofei LIU Yuqing | 2014 | Journal of Tongji University ( Natural Science)2014，42，7： | 1 |
| 18 | Trends of major hydroclimatic variables in the Tarim River ba-sin during the past50years显示文摘 | Xu Zongxue Liu Zhaofei Fu Guobin | 2010 | Journal of Arid Envi-ronments2010，74，2： | 1 |
| 19 | In-vitro internalization and irvvivo tumor uptake of anti-EGFR monoclonal antibody LA22 in A549 lung cancer cells and animal model显示文摘 | Liu Zhaofei Yu Zilin He Weiwei | 2009 | Cancer Biother Radiopharm2009，24，1： | 1 |
| 20 | Tumor targeting of ^(125)I-labeled anti-EGFR monoclonal antibody LA22 in HT-29 human colon cancer显示文摘Epidermal growth factor receptor (EGFR) plays a critical role in proliferation, apoptosis, angiogenesis, invasiveness and distant metastasis of tumors. In this study, the tumor targeting properties of anti-EGFR monoclonal antibody (mAb) LA22 in a colon cancer mouse model are evaluated. The results from flow cytometry assay and immunofluorescent staining clearly showed that HT-29 human colon cancer cells were EGFR positive, and the binding of mAb LA22 to the HT-29 cell surface was specific. The saturation binding experiment of 125I-LA22 to HT-29 cells revealed that LA22 possessed moderate affinity to EGFR with the Kd value calculated to be 3.28±0.76 nM. The in vivo γ imaging demonstrated the specific accumulation of 125I-LA22 in HT-29 tumor xenografts. The specific tumor targeting properties of mAb LA22 make it a good candidate for tumor targeted radioimmunotherapy of EGFR-positive tumors when it is labeled with therapeutic nuclides, such as 131I, 177Lu, or 90Y. | ZHAO Huiyun JIABing WANG Fan LIU Zhaofei | 2010 | Nuclear Science and Techniques2010，21，2： | 0 |
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