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| 1 | 声波激励的超小型纳机电系统磁电天线显示文摘当前的小型天线依赖于电磁波的谐振,因此天线的尺寸与电磁波波长相关。典型的天线尺寸大于波长的1/10,而进一步缩小天线尺寸在近十年来都是一个公开的挑战。介绍一种通过悬浮铁氧/压电薄膜异质结构的声波激励纳机械磁电天线。这种磁电天线通过其在声波谐振频率处的磁电效应接收和发射电磁波。磁电天线中的体声波激发铁磁薄膜的磁化振荡,产生电磁波的辐射;反之,天线感应电磁波的磁场,得到压电电压输出。这种磁电天线(尺寸仅为波长的千分之一)比现有小型天线的尺寸小1到2个数量级,但性能却没有降低,在便携式无线通信系统中具有很大的应用潜力。 | Tianxiang Nan Hwaider Lin Yuan Gao Alexei Matyushov Guoliang Yu Huaihao Chen Neville Sun Shengjun Wei Zhiguang Wang Menghui Li Xinjun Wang Amine Belkessam Rongdi Guo Brian Chen James Zhou Zhenyun Qian Yu Hui Matteo Rinaldi Michael E.McConney BrANDon M.Howe Zhongqiang Hu John G.Jones Gail J.Brown Nian Xiang Sun 张建强(翻译) 陈鼎鼎(审校) | 2017 | 通信对抗2017，36，4： | 8 |
| 2 | High density methane inclusions in Puguang Gasfield:Discovery and a T-P genetic study显示文摘Based on measurement of homogenization temperature of inclusions and Raman spectral analysis, high density methane inclusions were discovered in the Triassic reservoirs of Puguang Gasfield. The methane inclusions show a homogenization temperature Th = -117.5― -118.1℃, a corresponding density of 0.3455―0.3477 g/cm3, and a Raman scatter peak v1 shift varying between 2911―2910 cm-1, which signifies a very high density of methane inclusions. The salt water inclusions paragenetic with methane inclusions show a homogenization temperature Th=170―180℃. Based on the composition of methane inclusions as determined by Raman spectra, PVTsim software was used to simulate the trapping pressure for high density methane inclusions in geologic history, and the trapping pressure was found to be as high as 153―160 MPa. Even though Puguang Gasfield is currently a gas pool of normal pressure, and the fluid pressure for the gas pool ranges between 56―65 MPa. However, data from this study indicates that remarkable overpressure may be generated at the stage of mass production of gas cracked from oils in Cretaceous, as high density methane inclusions constitute key evidence for overpressure in gas pool in geologic history. Meanwhile, discovery of small amounts of H2S, CO2 or heavy hydrocarbon in part of the high density methane inclusions indicates that the geochemical environment for trapping of inclusions may be related to formation of H2S. Therefore, the observation results can help to explore the thermochemical sulfate reduction (TSR) conditions for oil cracking and H2S formation. | LIU Delian DAI JinXing XIAO XianMing TIAN Hui YANG Chun HU AnPing MI JingKui SONG ZhiGuang | 2009 | Chinese Science Bulletin2009，54，24： | 8 |
| 3 | High-throughput experiments facilitate materials innovation:A review显示文摘Since the Material Genome Initiative(MGI) was proposed, high-throughput based technology has been widely employed in various fields of materials science. As a theoretical guide, material informatics has been introduced based on machine learning and data mining and high-throughput computation has been employed for large scale search, narrowing down the scope of the experiment trials. High-throughput materials experiments including synthesis, processing, and characterization technologies have become valuable research tools to pin down the prediction experimentally, enabling the discovery-to-deployment of advances materials more efficiently at a fraction of cost. This review aims to summarize the recent advances of high-throughput materials experiments and introduce briefly the development of materials design based on material genome concept. By selecting representative and classic works in the past years, various high-throughput preparation methods are introduced for different types of material gradient libraries, including metallic, inorganic materials, and polymers. Furthermore, high-throughput characterization approaches are comprehensively discussed, including both their advantages and limitations. Specifically, we focus on high-throughput mass spectrometry to analyze its current status and challenges in the application of catalysts screening. | LIU Yi Hao HU ZiHeng SUO ZhiGuang HU LianZhe FENG LingYan GONG XiuQing LIU Yi ZHANG JinCang | 2019 | Science China(Technological Sciences)2019，62，4： | 7 |
| 4 | Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function显示文摘Innate immunity mediated by Toll-like receptors(TLRs),which can recognize pathogen molecular patterns,plays a critical role in type 1 diabetes development.TLR7 is a pattern recognition receptor that senses single-stranded RNAs from viruses and host tissue cells;however,its role in type 1 diabetes development remains unclear.In our study,we discovered that Tlr7-deficient(Tlr7^(−/−))nonobese diabetic(NOD)mice,a model of human type 1 diabetes,exhibited a significantly delayed onset and reduced incidence of type 1 diabetes compared with Tlr7-sufficient(Tlr7^(+/+))NOD mice.Mechanistic investigations showed that Tlr7 deficiency significantly altered B-cell differentiation and immunoglobulin production.Moreover,Tlr7^(−/−)NOD B cells were found to suppress diabetogenic CD4^(+)T-cell responses and protect immunodeficient NOD mice from developing diabetes induced by diabetogenic T cells.In addition,we found that Tlr7 deficiency suppressed the antigen-presenting functions of B cells and inhibited cytotoxic CD8^(+)T-cell activation by downregulating the expression of both nonclassical and classical MHC class I(MHC-I)molecules on B cells.Our data suggest that TLR7 contributes to type 1 diabetes development by regulating B-cell functions and subsequent interactions with T cells.Therefore,therapeutically targeting TLR7 may prove beneficial for disease protection. | Juan Huang Jian Peng James Alexander Pearson Georgios Efthimiou Youjia Hu Ningwen Tai Yanpeng Xing Luyao Zhang Jianlei Gu Jianping Jiang Hongyu Zhao Zhiguang Zhou F.Susan Wong Li Wen | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 5 | Association between essential hypertension and polymorphisms of beta 1 adrenergic receptor gene G1165C (Gly389Arg) in Chinese Mongolian population显示文摘BACKGROUND: The prevalences of hypertension, cerebrovascular diseases, etc. are higher in Mongolian population because of the influence of various factors including genetics, geography, diet, etc. Therefore, it is helpful to develop researches on the genetics of various diseases including hypertension in Mongolian population. OBJECTIVE: To analyze the association between the polymorphism of beta1 adrenergic receptor (β1-AR) gene G1165C (Arg389Gly), an important candidate gene for various diseases of cardiovascular system, and essential hypertension in Mongolian population. DESIGN: A cross-sectional study. SETTINGS: Department of Neurology, the First Affiliated Hospital of Inner Mongolia Medical College; Wulate Houqi Red Cross Society. PARTICIPANTS: The survey was carried out from February 2003 to March 2005. Totally 239 Mongolian residents, whose blood relations of 3 generations were all Mongolians, were selected from Wulate Houqi, Inner Mongolia, and they were all informed with the survey and detected items. Based on the diagnostic standard of hypertension set by WHO in 1999, the subjects were divided into two groups according to the level blood pressure: ① Normal blood pressure group (n=117): systolic blood pressure (SBP) < 140 mm Hg (1 mm Hg =0.133 kPa), diastolic blood pressure (DBP) < 90 mm Hg, and those having histories of cerebrovascular disease, heart disease, diseases of liver, kidney and tiroides, and diabetes mellitus were excluded. ② Essential hypertension group (n=122): including 51 patients with simple high SBP. All the enrolled subjects had no blood relationship with each other, and had no history of miscegenation. METHODS: The body height, body mass, waist circumference and blood lipids were measured routinely, and their habits of smoking and drinking were also investigated. Peripheral venous blood (5 mL) was drawn, the genome DNA was extracted, and the polymorphisms of the β1-AR G1165C (Gly389Arg) genotype were detected with the Sequenom system. Polymerase chain reaction (PCR) experiment and SNP detection were performed in Huada Gene Laboratory of Bejing, then the univariate analysis of variance was applied in the sample comparison among groups, and the chi-square test was used to compare the genotypes and allele frequencies. The odd ratio (OR) and 95% confidence interval (CI) were calculated. MAIN OUTCOME MEASURES: The distributions of β1-AR G1165C (Gly389Arg) genotypes and alleles were observed. RESULTS: All the 239 subjects were involved in the analysis of results, and no one missed. ①Comparison of β1-AR G1165C (Gly389Arg) genotypes and allele distributions: In Mongolian population, the frequencies of CC and GG+GC genotypes at β1-AR G1165C (Gly389Arg) site in the essential hypertension group (72%, 28%) were not significantly different from those in the normal blood pressure group (67%, 33%) (χ2=0.841, P=0.359; OR: 0.773, 95%CI: 0.445-1.342); The frequencies of C and G alleles also had no significant differences between the essential hypertension group (85%, 15%) and the normal blood pressure group (82%, 18%) (χ2=1.136, P=0.287; OR: 0.769, 95%CI: 0.747-1.248). ②The frequencies of CC and GG+GC genotypes at β1-AR G1165C (Gly389Arg) site had no significant differences between the patients with simple high SBP (71%, 29%) and the normal blood pressure group (χ2=0.250, P=0.617; OR: 0.833, 95%CI: 0.408-1.703); The frequencies of C and G alleles were not significantly different between the patients with simple high SBP (86%, 14%) and the normal blood pressure group (χ2=0.670, P=0.413; OR: 0.766, 95%CI: 0.404-1.453). CONCLUSION: In Mongolian population, the distributions of the genotypes and alleles of β1-AR G1165C (Gly389Arg) have no obvious differences between the subjects with normal blood pressure and the patients with essential hypertension (including simple SBP increase), which suggests that G1165C (Glu389Asp) site of β1-AR gene may be not a genetic mark of essential hypertension and simple high SBP in Mongolian population. | Rile Hu Rile Hu Shigang Zhao Guangming Niu Chunyu Zhang Zhiguang Wang Mingfang Jiang | 2006 | Neural Regeneration Research2006，1，3： | 2 |
| 6 | Rheb promotes brown fat thermogenesis by Notch-dependent activation of the PKA signaling pathway显示文摘Increasing brown and beige fat thermogenesis have an anti-obesity effect and thus great metabolic benefits.However,the molecular mechanisms regulating brown and beige fat thermogenesis remain to be further elucidated.We recently found that fat-specific knockout of Rheb promoted beige fat thermogenesis.In the current study,we show that Rheb has distinct effects on thermogenic gene expression in brown and beige fat.Fat-specific knockout of Rheb decreased protein kinase A(PKA)activity and thermogenic gene expression in brown adipose tissue of high-fat diet-fed mice.On the other hand,overexpression of Rheb activated PKA and increased uncoupling protein 1 expression in brown adipocytes.Mechanistically,Rheb overexpression in brown adipocytes increased Notch expression,leading to disassociation of the regulatory subunit from the catalytic subunit of PKA and subsequent PKA activation.Our study demonstrates that Rheb,by selectively modulating thermogenic gene expression in brown and beige adipose tissues,plays an important role in regulating energy homeostasis. | Wen Meng Xiuci Liang Ting Xiao Jing Wang Jie Wen Hairong Luo Jianhui Teng Yanquan Fei Qinghai Zhang Bilian Liu Fang Hu juli Bai Meilian Liu Zhiguang Zhou Feng Liu | 2019 | Journal of Molecular Cell Biology2019，11，9： | 2 |
| 7 | Genetic predisposition to essential hypertension in a Mongolian population Detecting the C825T polymorphism of the G-protein beta 3 subunit gene显示文摘BACKGROUND: The prevalences of hypertension, cerebrovascular diseases, etc. are higher in Mongolian population because of the influence of various factors including genetics, geography, diet, etc. Therefore, it is helpful for prevention to develop researches on the genetics of various diseases including hypertension in Mongolian population. OBJECTIVE: To analyze the association between C825T polymorphisms of G-protein beta 3 subunit gene (GNB3), the important candidate gene of various disease of cardiovascular system, and Mongolian patients with essential hypertension. DESIGN: A comparative observation. SETTINGS: Department of Neurology, the First Affiliated Hospital of Inner Mongolia Medical College; Wulate Houqi Red Cross Society. PARTICIPANTS: Totally 267 Mongolian residents, whose blood relations of 3 generations were all Mongolians, were selected from Wulate Houqi, Inner Mongolia. The patients were screened based on the diagnostic standard of hypertension set by WHO in 1999, and the enrolled subjects were divided into two groups according to the level of blood pressure: ① Normal blood pressure group (n =124): 64 males and 60 females, systolic blood pressure (SBP) < 140 mm Hg (1 mm Hg=0.133 kPa), diastolic blood pressure (DBP) < 90 mm Hg; ② Essential hypertension group (n =143): 71 males and 72 females, including 60 patients with simple high SBP (SBP ranged 145 to 195 mm Hg, whereas DBP < 90 mm Hg). METHODS: Peripheral venous blood (5 mL) was drawn from all the subjects, the genome DNA was extracted, and the polymorphisms of the GNB3 C825T genotype were detected with the Sequenom system. Polymerase chain reaction (PCR) experiment and SNP detection were performed in Beijing Huada gene laboratory. Then the univariate analysis of variance was applied in the sample comparison among groups, and the chi-square test was used to compare the genotypes and allele frequencies. The odd ratio (OR) and 95% confidence interval (CI) were calculated. MAIN OUTCOME MEASURES: The distributions of GNB3 C825T genotypes and alleles were observed. RESULTS: All the 267 Mongolian subjects were involved in the analysis of results. ① GNB3 C825T genotypes: In Mongolian population, the frequencies of CC, CT and TT genotypes at GNB3 C825T site in the essential hypertension group (48%, 41%, 11%) were not obvious different from those in the normal blood pressure group (43%, 47%, 10%,χ2 =0.162, P =0.688; OR:1.176, 95%CI: 0.533–2.592), whereas there were also no obvious differences between the simple high SBP group (57%, 35%, 8%) and the normal blood pressure group (χ2 =0.733, P =0.392; OR:1.957, 95%CI: 0.623–6.143). ② GNB3 C825T alleles: In Mongolian population, The frequencies of C and T alleles in the essential hypertension group (69%, 31%) were not obviously different from those in the normal blood pressure group (67%, 33%, χ2 =0.094, P = 0.759; OR:0.945, 95%CI: 0.657–1.358), whereas there were also no obvious differences between the simple high SBP group (74%, 26%) and the normal blood pressure group (χ2 =2.133, P =0.144; OR:0.697, 95%CI: 0.428–1.133). CONCLUSION: GNB3 C825T site may be not a genetic marker of essential hypertension and simple highSBP in Mongolian population. | Chunyu Zhang Shigang Zhao Guangming Niu Rile Hu Zhiguang Wang Mingfang Jiang | 2007 | Neural Regeneration Research2007，2，3： | 1 |
| 8 | Occurrence and impact of polychlorinated dibenzo-p-dioxins/dibenzofurans in the air and soil around a municipal solid waste incinerator显示文摘To assess the influence of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans(PCDD/Fs) on the environment in the vicinity of municipal solid waste incinerators(MSWIs), we determined the levels of PCDD/Fs in air and soil samples collected around a MSWI, which is the largest in China. The International Toxicity Equivalency Quantity(I-TEQ) concentrations of PCDD/Fs in air samples were from 0.0300 to 1.03 pg I-TEQ/m^3(0.445–13.6 pg/m^3), with an average of 0.237 pg I-TEQ/m^3, while in soil samples they ranged from 0.520 to 3.40 pg I-TEQ/g(2.41–88.7 pg/g) with an average of1.49 pg I-TEQ/g. The concentrations of PCDD/Fs in air and soil samples were comparable to other areas, and Pe CDFs were the dominant contributors, which was different from stack gas homologue patterns. Multivariate statistical analysis showed that PCDD/Fs emission from the MSWI did not directly affect the profiles of PCDD/Fs in air and soils, so that vehicles and unidentified emission sources should be considered. The daily inhalation levels of PCDD/Fs for children(0.0110 to 0.392 pg I-TEQ/(kg·day) and adults(0.00600 to 0.221 pg I-TEQ/(kg·day) near the MSWI were lower than the tolerable daily intake of 1.00 to 4.00 pg WHO-TEQ/(kg·day), but in winter the values were higher than in summer. These results can be used as basic data for assessing the risk of PCDD/Fs exposure in residents living around this MSWI, and more monitoring programs and studies should be carried out around MSWIs. | Zhiguang Zhou Yue Ren Jiazhi Chu Nan Li Sen Zhen Hu Zhao Shuang Fan Hui Zhang Pengjun Xu Li Qi Shuting Liang Bin Zhao | 2016 | Journal of Environmental Sciences2016，28，6： | 1 |
| 9 | Compressed sensing of superimposed chirps with adaptive dictionary refinement显示文摘The compressed sensing(CS)theory shows that accurate signal reconstruction depends on presetting an appropriate signal sparsifying dictionary.For CS of superimposed chirps,this dictionary is typically taken to be a waveform-matched dictionary formed by blindly discretizing the frequency-chirp rate plane.However,since practical target parameters do not lie exactly on gridding points of the assumed dictionary,there is always mismatch between the assumed and the actual sparsifying dictionaries,which will cause the performance of conventional CS reconstruction methods to degrade considerably.To address this,we model the waveformmatched sparsifying dictionary as a parameterized one by treating its sampled frequency-chirp rate grid points as the underlying parameters.As a consequence,the sparsifying dictionary becomes refnable and its refnement can be achieved by optimizing the underlying parameters.Based on this,we develop a novel reconstruction algorithm for CS of superimposed chirps by utilizing the variational expectation-maximization(EM)algorithm.By alternating between steps of sparse coefcients estimation and dictionary parameters optimization,the algorithm integrates the process for dictionary refnement into that of signal reconstruction,and thus can achieve sparse reconstruction and dictionary optimization simultaneously.Experimental results demonstrate that the algorithm efectively deals with the performance degradation incurred by dictionary mismatch,and also outperforms the state-of-the-art CS reconstruction methods both in compressing the signal measurements and in suppressing the measurement noise. | HU Lei ZHOU JianXiong SHI ZhiGuang FU Qiang | 2013 | Science China(Information Sciences)2013，56，12： | 1 |
| 10 | A provably secure proxy signature scheme in certificateless cryptography显示文摘 | Hu Xiong Li F Qin Zhiguang | 2010 | Intema- tional Journal of Informatica2010，20，2： | 1 |
| 11 | Abnormal hypermethylation of promoter region downregulates chemokineCXC ligand 14 expression in gastric cancer显示文摘 | Changyuan Hu Feng Lin Guangbao Zhu Xiangyang Xue Yujie Ding Zhiguang Zhao Lifang Zhang Xian Shen | 2013 | International Journal of Oncology2013，，5： | 1 |
| 12 | Secure Vehicle-to-roadside Communication Protocol Using Certificate-based Cryptosystem显示文摘 | Hu Xiong Zhiguang Qin Fagen Li | 2010 | IETE Technical Review2010，，3： | 1 |
| 13 | An improved certificateless signature scheme secure in the standard model显示文摘 | Xiong Hu Qin Zhiguang Li Fagen | 2008 | Fundamenta Imformaticae2008，88，1： | 1 |
| 14 | GRB10 regulates β-cell mass by inhibiting β-cell proliferation and stimulating β-cell dedifferentiation显示文摘Decreased functional β-cell mass is the hallmark of diabetes, but the cause of this metabolic defect remains elusive. Here, we show that the levels of the growth factor receptor-bound protein 10(GRB10), a negative regulator of insulin and m TORC1 signaling, are markedly induced in islets of diabetic mice and high glucose-treated insulinoma cell line INS-1 cells. β-cell-specific knockout of Grb10 in mice increased β-cell mass and improved β-cell function. Grb10-deficient β-cells exhibit enhanced m TORC1 signaling and reduced β-cell dedifferentiation, which could be blocked by rapamycin. On the contrary, Grb10 overexpression induced β-cell dedifferentiation in MIN6 cells. Our study identifies GRB10 as a critical regulator of β-cell dedifferentiation and β-cell mass, which exerts its effect by inhibiting m TORC1 signaling. | Zixin Cai Fen Liu Yan Yang Dandan Li Shanbiao Hu Lei Song Shaojie Yu Ting Li Bilian Liu Hairong Luo Weiping Zhang Zhiguang Zhou Jingjing Zhang | 2022 | Journal of Genetics and Genomics2022，49，3： | 1 |
| 15 | On the Security of an Efficient and Non-interactive Hierarchical Key Agreement Protocol显示文摘 | Guobin Zhu Hu Xiong Zhiguang Qin | 2014 | Wireless Personal Communications2014，，2： | 1 |
| 16 | A possible endoscopic therapy for large hiatal hernia complicated with refractory gastroesophageal reflux disease显示文摘A hiatal hernia(HH)is usually associated with gastroesophageal reflux disease(GERD).An HH can increase the incidence of GERD.[1]The coexistence of these diseases increases the difficulty of treatment and can be challenging for endoscopic treatment.Therapeutic methods for small HHs(≤2 cm)combined with refractory GERD have recently been emerging.However,there are still knowledge gaps in the endoscopic treatment of large HHs(≥3cm)combined with refractory GERD.We developed a new endoscopic method called hiatal hernia-endoscopic submucosal dissection(HH-ESD)and performed the present study to clarify the efficacy and safety of HH-ESD. | Haijing Zhang Haiping Zhao Mingxing Hou Chunlu Jin Rui Rui Baiyinbatu Xie Ying Li Zhiguang Hu Guanlan Liu Feng Guo Haiqing Hu | 2022 | Chinese Medical Journal2022，，8： | 1 |
| 17 | Vector analysis of electric-field-induced antiparallel magnetic domain evolution in ferromagnetic/ferroelectric heterostructures显示文摘Electric field(E-field)control of magnetism based on magnetoelectric coupling is one of the promising approaches for manipulating the magnetization with low power consumption.The evolution of magnetic domains under in-situ E-fields is significant for the practical applications in integrated micro/nano devices.Here,we report the vector analysis of the E-field-driven antiparallel magnetic domain evolution in FeCoSiB/PMN-PT(011)multiferroic heterostructures via in-situ quantitative magneto-optical Kerr microscope.It is demonstrated that the magnetic domains can be switched to both the 0°and 180°easy directions at the same time by E-fields,resulting in antiparallel magnetization distribution in ferromagnetic/ferroelectric heterostructures.This antiparallel magnetic domain evolution is attributed to energy minimization with the uniaxial strains by E-fields which can induce the rotation of domains no more than 90°.Moreover,domains can be driven along only one or both easy axis directions by reasonably selecting the initial magnetic domain distribution.The vector analysis of magnetic domain evolution can provide visual insights into the strain-mediated magnetoelectric effect,and promote the fundamental understanding of electrical regulation of magnetism. | Xinger ZHAO Zhongqiang HU Jingen WU Ting FANG Yaojin LI Yuxin CHENG Yifan ZHAO Mengmeng GUAN Dan XIAN Chenying WANG Qi MAO Bin PENG Ren-Ci PENG Ziyao ZHOU Zhiguang WANG Zhuang-De JIANG Ming LIU | 2021 | Journal of Advanced Ceramics2021，10，6： | 0 |
| 18 | Establishment of NaLuF_(4):15%Tb-based low dose X-PDT agent and its application on efficient antitumor therapy显示文摘X-ray excited photodynamic therapy(X-PDT)is the bravo answer of photodynamic therapy(PDT)for deep-seated tumors,as it employs X-ray as the irradiation source to overcome the limitation of light penetration depth.However,high X-ray irradiation dose caused organ lesions and side effects became the major barrier to X-PDT application.To address this issue,this work employed a classic-al co-precipitation reaction to synthesize NaLuF_(4):15%Tb^(3+)(NLF)with an average particle size of(23.48±0.91)nm,which was then coupled with the photosensitizer merocyanine 540(MC540)to form the X-PDT system NLF-MC540 with high production of singlet oxygen.The system could induce antitumor efficacy to about 24%in relative low dose X-ray irradiation range(0.1-0.3 Gy).In vivo,when NLF-MC540 irradiated by 0.1 Gy X-ray,the tumor inhibition percentage reached 89.5%±5.7%.The therapeutic mechanism of low dose X-PDT was found.A significant increase of neutrophils in serum was found on the third day after X-PDT.By immunohistochemical staining of tumor sections,the Ly6G^(+),CD8^(+),and CD11c^(+)cells infiltrated in the tumor microenvironment were studied.Utilizing the bilat-eral tumor model,the NLF-MC540 with 0.1 Gy X-ray irradiation could inhibit both the primary tumor and the distant tumor growth.De-tected by enzyme linked immunosorbent assay(ELISA),two cytokines IFN-γand TNF-αin serum were upregulated 7 and 6 times than negative control,respectively.Detected by enzyme linked immune spot assay(ELISPOT),the number of immune cells attributable to the IFN-γand TNF-αlevels in the group of low dose X-PDT were 14 and 6 times greater than that in the negative control group,respectively.Thus,it conclude that low dose X-PDT system could successfully upregulate the levels of immune cells,stimulate the secretion of cy-tokines(especially IFN-γand TNF-α),activate antitumor immunity,and finally inhibit colon tumor growth. | Yi Tian Zhiguang Fu Xiaosheng Zhu Chunjing Zhan Jinwei Hu Li Fan Chaojun Song Qian Yang Yu Wang Mei Shi | 2024 | International Journal of Minerals,Metallurgy and Materials2024，31，3： | 0 |
| 19 | Unconventional piezoelectric coefficients in perovskite piezoelectric ceramics显示文摘Piezoelectric ceramics exhibit three conventional piezoelectric coefficients,i.e.,d33,d31,d15,due to their∞mm crystal symmetry.Unconventional piezoelectric coefficients,such as d11,d12,d13,d14,d16,etc.,can only be extracted from piezoelectric single crystals of special symmetry with specific cut direction.Here we demonstrate a rotated poling method to realize unconventional piezoelectric coefficients in perovskite piezoelectric ceramics.This method is elaborated in theory and experimentally proven to be effective.Full nonzero piezoelectric coefficients in the 36 piezoelectric coefficients matrix can be obtained by combining these“quasi(effective)piezoelectric coefficients”with the conventional piezoelectric coefficients,which would expand applications in a wide variety of piezoelectric devices. | Jingen Wu Zhongqiang Hu Xiangyu Gao Miaomiao Cheng Xinger Zhao Wei Su Liqian Wang Mengmeng Guan Yongjun Du Ruohao Mao Zhiguang Wang Ziyao Zhou Shuxiang Dong Ming Liu | 2021 | Journal of Materiomics2021，7，2： | 0 |
| 20 | From charge storage mechanism to performance:A strategy toward boosted lithium/sodium storage through heterostructure optimization显示文摘Solving the problems of low electrical conductivity and poor cycling durability in transition metal oxidesbased anode materials for lithium-ion batteries(LIBs)and sodium-ion batteries(SIBs)has already turned into an urgent requirement.In this paper,we successfully synthesized Co_(2)VO_(4)/Co compounds with Co-VMOF(metal-organic framework)as a sacrificial template and investigated their electrochemical mechanism in order to improve the electrochemical properties of LIBs and SIBs.The optimized heaping configuration and the existence of metallic Co catalyzed the formation of radical ions,thereby facilitating higher conductivity,shortening Li+and Na+transport paths,and providing more active sites.Co_(2)VO_(4)/Co constructed with 2-methylimidazole as a ligand showed a discharge capacity of 1605.1 mA h g^(-1)after 300 cycles at 0.1 A g^(-1)in LIB and 677.2 mA h g^(-1)in SIB.Density functional theory(DFT)calculation emphasizes the crucial role of Co_(2)VO_(4)/Co in enhancing electrode conductivity,decreasing the migratory energy barrier,and thereby strengthening electrochemical properties.This heterostructure building technique may pave the way for the development of high-performance LIBs and SIBs.Furthermore,the problem of the low first-loop coulombic efficiency faced by transition metal oxides is improved. | Xiaoke Zhang Guangfa Deng Mianying Huang Zhaohui Xu Jianlin Huang Xuan Xu Zhiguang Xu Maochan Li Lei Hu Xiaoming Lin | 2024 | Journal of Energy Chemistry2024，88，1： | 0 |
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