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| 1 | Pragmatics and the Teaching and Leaning of English显示文摘The purpose of the teaching and the learning of English is to develop communicative competence .Pragmatics is one of the most essential parts of the communicative competence .It concerns the appropriate use of language. This paper aims to show the significant role of pragmatics in the teaching and learning of English and further exploresthe importance of cultivating students awareness to improve their pragmatic ability and communicative competence. | Li Wei (Department of English, Zhunyi Teacher’s College) | 2001 | 铜仁师专学报2001，3，1： | 1 |
| 2 | Intrahepatic Expression of Programmed Death-1 and its Ligands in Patients with HBV-Related Acute-on-Chronic Liver Failure显示文摘 | Dayan Cao Huan Xu Guoning Guo Zhihua Ruan Lei Fei Zhunyi Xie Yuzhang Wu Yongwen Chen | 2013 | Inflammation2013，，1： | 1 |
| 3 | siRNA screening of Rab GTPases reveal a role of Rab3b and Rab3c positive vesicles in cross presentation显示文摘Antigen cross-presentation in dendritic cells is a complex intracellular membrane transport process, but the underlying molecular mechanisms remain to be thoroughly investigated. | Liyun Zou, Jingran Zhou, Jinyu Zhang, Jingyi Li, Na Liu, Lingling Chai, Na Li, Ting Liu, Liqi Li, Zhunyi Xie, Hongli Liu, Ying Wan, Yuzhang Wu.Institute of Immunology,PLA, The Third Military Medical University, Chongqing 400038 | 2009 | 生物物理学报2009，25，S1： | 1 |
| 4 | The characteristic expression of B7‐H3 and B7‐H4 in liver biopsies from patients with HBV‐related acute‐on‐chronic liver failure显示文摘 | Guoning Guo Dayan Cao Huan Xu Zhihua Ruan Lei Fei Zhunyi Xie Yuzhang Wu Yongwen Chen | 2012 | Pathology International2012，，10： | 1 |
| 5 | Indirect Speech Acts显示文摘Indirect speech acts are frequently used in verbal communication, the interpretation of them is ofgreat importance in order to meet the demands of the development of students’ communicative competence. Thispaper, therefore, intends to present Searle’ s indirect speech acts and explore the way how indirect speech acts areinterpreted in accordance ’with two influential theories. It consists of four parts. Part one gives a generalintroduction to the notion of speech acts theory. Part two makes an elaboration upon the conception of indirect speechact theory proposed by Searle and his supplement and development of illocutionary acts. Part three deals with theinterpretation of indirect speech acts. Part four draws implication from the previous study and also serves as theconclusion of the dissertation . | LiWei(Department of English,Zhunyi Teachers’ college) | 2001 | 遵义师范高等专科学校学报2001，3，1： | 0 |
| 6 | Liver X receptorβis required for the survival of single-positive thymocytes by regulating IL-7Rαexpression显示文摘Liver X receptors(LXRs)are known as key transcription factors in lipid metabolism and have been reported to play an important role in T-cell proliferation.However,whether LXRs play a role in thymocyte development remains largely unknown.Here,we demonstrated that LXRβdeficiency caused a reduction in single-positive(SP)thymocytes,whereas the transitions from the double-negative to SP stage were normal.Meanwhile,LXRβ-null SP thymocytes exhibited increased apoptosis and impairment of the IL-7Rα-Bcl2 axis.In addition,the LXR agonist T0901317 promoted the survival of SP thymocytes with enhanced IL-7Rαexpression in wild-type mice but not in LXRβ-deficient mice.Mechanistically,LXRβpositively regulated the expression of IL-7Rαvia direct binding to the Il7r allele in SP thymocytes,and forced expression of IL-7Rαor Bcl2 restored the survival of LXRβ-defective SP thymocytes.Thus,our results indicate that LXRβfunctions as an important transcription factor upstream of IL-7Rαto promote the survival of SP thymocytes. | Huang Huang Xiaoping Wu Dongwei Meng Yizhou Feng Lan Zhou Zhenyu Liu Shupei Tang Xueqin Li Yi Cao Haiyang He Zhunyi Xie Jingbo Zhang Yongwen Chen Tingting Zhao Yuzhang Wu Xinyuan Zhou | 2021 | Cellular & Molecular Immunology2021，18，8： | 0 |
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