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| 1 | Survival of geriatric patients after percutaneous endoscopic gastrostomy in Japan显示文摘AIM: To examine the long term survival of geriatric patients treated with percutaneous endoscopic gastrostomy (PEG) in Japan. METHODS: We retrospectively included 46 Japanese community and tertiary hospitals to investigate 931 consecutive geriatric patients (≥ 65 years old) with swallowing difficulty and newly performed PEG between Jan 1st 2005 and Dec 31st 2008. We set death as an outcome and explored the associations among patient’s characteristics at PEG using log-rank tests and Cox proportional hazard models. RESULTS: Nine hundred and thirty one patients were followed up for a median of 468 d. A total of 502 deaths were observed (mortality 53%). However, 99%, 95%, 88%, 75% and 66% of 931 patients survived more than 7, 30, 60 d, a half year and one year, respectively. In addition, 50% and 25% of the patients survived 753 and 1647 d, respectively. Eight deaths were considered as PEG-related, and were associated with lower serum albumin levels (P = 0.002). On the other hand, among 28 surviving patients (6.5%), PEG was removed. In a multivariate hazard model, older age [hazard ratio (HR), 1.02; 95% confidence interval (CI), 1.00-1.03; P = 0.009], higher C-reactive protein (HR, 1.04; 95% CI: 1.01-1.07; P = 0.005), and higher blood urea nitrogen (HR, 1.01; 95% CI: 1.00-1.02; P = 0.003) were significant poor prognostic factors, whereas higher albumin (HR, 0.67; 95% CI: 0.52-0.85; P = 0.001), female gender (HR, 0.60; 95% CI: 0.48-0.75; P < 0.001) and no previous history of ischemic heart disease (HR, 0.69; 95% CI: 0.54-0.88, P = 0.003) were markedly better prognostic factors. CONCLUSION: These results suggest that more than half of geriatric patients with PEG may survive longer than 2 years. The analysis elucidated prognostic factors. | Yutaka Suzuki Seryna Tamez Akihiko Murakami Akihiko Taira Akihiro Mizuhara Akira Horiuchi Chie Mihara Eiji Ako Hirohito Muramatsu Hitoshi Okano Hitoshi Suenaga Kazuaki Jomoto Junya Kobayashi Katsunari Takifuji Kazuhiro Akiyama Koh Tahara Koji Onishi Makoto Shimazaki Masami Matsumoto Masashi Ijima Masato Murakami Masato Nakahori Michiaki Kudo Michio Maruyama Mikako Takahashi Naohiro Washizawa Shigeru Onozawa Satoshi Goshi Satoyoshi Yamashita Shigeki Ono Shin Imazato Shinji Nishiwaki Shuichirou Kitahara Takao Endo Takao Iiri Takeshi Nagahama Takuto Hikichi Tatsuya Mikami Tetsuo Yamamoto Tetsushi Ogawa Tomoko Ogawa Tomoyuki Ohta Toshifumi Matsumoto Toshiroh Kura Tsutomu Kikuchi Tsuyoshi Iwase Tsuyotoshi Tsuji Yukio Nishiguchi Mitsuyoshi Urashima | 2010 | World Journal of Gastroenterology2010，16，40： | 4 |
| 2 | Anxiety associated with parachute jumping显示文摘 | Kowalczyk E Kura M Ciewierz J | 2012 | Pol Merkur Lekarski2012，33，194： | 1 |
| 3 | Effects of single low dose irra- diation on subventricular zone cells in juvenile rat brain 显示文摘 | Amano T lnamura T Kura S | 2002 | Neurol Res2002，24，： | 1 |
| 4 | Characterization of Legionella pneumophila isolates from patients in Japanaccording to serogroups, monoclonaiantibody subgroups and sequencetypes显示文摘 | Amemura-Maekawa J Kura F Helbig JH | 2010 | J MedMicrobiol2010，59，： | 1 |
| 5 | Cervicofaciai actinomycosis mimicking lymphangioma circumscriptum显示文摘 | Kura MM Rane VK | | 0，，： | 1 |
| 6 | Oscillation theorems for a second order sub linear ordinary differential equation 显示文摘 | Kura T | 1982 | Proceedings of the American Mathematical Society1982，84，4： | 1 |
| 7 | Candida tropicalis : It- sprevalence,pathogenicity and increasing resistance to fluconazole显示文摘 | KothavadeRJ Kura MM Valand AG | 2010 | J Med Microbiol2010，59，8： | 1 |
| 8 | Ginkgo biloba compared with cholin- esterase inhibitors in the treatment of dementia: a review based on meta-analyses by the Cochrane Collaboration显示文摘 | Kura A Baelen BV | 2004 | Dement Geriatr Cogn Disord2004，18，2： | 1 |
| 9 | Energy efficiency improvement of series hybrid vehicle显示文摘 | AOYAGI SATOSHI YUSUKE HASEGAWA TAKAHIRO YONE KURA | 2001 | JSAE Review2001，22，3： | 1 |
| 10 | Pharmacologieal effects off lavonoids from Scutellaria baicalensis显示文摘 | Kowalczyk E Kazesifiski P Kura M | 2006 | Przgel Lek2006，63，2： | 1 |
| 11 | Legionella pneumophila serogroup 1 isolates from cooling towers in Japan form a distinct genetic cluster显示文摘 | Amemura-Maekawa J Kura F Chang B | 2005 | Microbiol Immunol2005，49，12： | 1 |
| 12 | 显示文摘 | Frost P D Kura J G Eastwood L W | 1950 | Trans AIME1950，188，： | 1 |
| 13 | Fruit plant germplasm characterization using molecular markers generated in RAPD and ISSR-PCR 显示文摘 | Korbin M Kuras A Zurawicz E | 2002 | Cellular and Molecular Biology Letters2002，7，： | 1 |
| 14 | An adaptive robustizing approach to kalman filtering显示文摘 | Tsai C Kura L | 1983 | Automatic1983，19，3： | 1 |
| 15 | Ultrastructure of meiocyte in ovules of Orchis and Epipactis显示文摘 | KUDLICKA K KURAS M | 1979 | Bull Acad Polon Sci Ser Sci Biol1979，26，： | 1 |
| 16 | Study of risk factors associated with HIV seropositivity in STD patients at Mumbai, India显示文摘 | Pedhambkar RB Pedhambkar BS Kura MM | 2001 | Sex Transm infect2001，77，5： | 1 |
| 17 | OICETS on-orbit laser communication experiments 显示文摘 | JONO AKASHI TAKAYAMA YOSHIHISA KURA NOBUHIRO | 2006 | Free-Spaee Laser Communication Technologies XVIII2006，61，5： | 1 |
| 18 | Development and reliability of a standard rating system for outcome measurement of foot and ankle disorders I: development of standard rating system显示文摘 | Hisateru Niki Haruhito Aoki Suguru Inokuchi Satoru Ozeki Mitsuo Kinoshita Hideji Kura Yasuhito Tanaka Masahiko Noguchi Shigeharu Nomura Masahito Hatori Shinobu Tatsunami | 2005 | Journal of Orthopaedic Science2005，，5： | 1 |
| 19 | Anthocyanins in medicine 显示文摘 | Kowalczyk E Krzesinski P Kura M | 2003 | Pol J Pharmacol2003，55，5： | 1 |
| 20 | Oscillation theorems for a scend order sublinear ordinary differentional equations显示文摘 | Kura T | 1982 | Proe Amer Math Soc1982，84，： | 1 |
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