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| 1 | 犬体内细粒棘球绦虫和多房棘球绦虫的混合感染显示文摘目的 证实家犬体内是否存在细粒棘球绦虫和多房棘球绦虫混合感染。方法 从新疆和静县巴音布鲁克草原现场收购的30条牧羊犬,经麻醉后处死解剖,在1只雌性牧羊犬小肠内发现棘球绦虫成虫1万条以上,经显微镜观察,疑为细粒棘球绦虫和多房棘球绦虫混合感染。用Eglf/r和EM-15/17EM引物分别对两种棘球绦虫的线粒体DNA特异目的片段进行序列分析鉴定。结果 形态学观察:细粒棘球绦虫孕节长大,生殖孔偏后,位于节片一侧中部。子宫有不规则的分支和侧突(侧囊),内含虫卵200~800个。多房棘球绦虫较短小,4~5体节。孕节中子宫呈简单的囊状,无侧囊。生殖孔开口于侧缘的前半部。线粒体12S RNA序列鉴定,扩增样本DNA经同源序列比较发现,与细粒棘球绦虫G1型具有相同的序列;扩增样本与多房棘球绦虫具有相同的序列。分别确定为细粒棘球绦虫和多房棘球绦虫两种虫种。结论 首次证实家犬体内存在细粒棘球绦虫和多房棘球绦虫的混合感染。 | 温浩 张亚楼 Jean-Mathieu BART Giraudoux P Vuitton DA 马旭东 邹林樾 苗玉清 Craig PS | 2006 | 中国寄生虫学与寄生虫病杂志2006，24，1： | 18 |
| 2 | 常规脂蛋白检测和载脂蛋白在心血管病预测中的比较显示文摘总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。 | Welsh C Celis-Morales CA Brown R Mackay DF Lewsey J Mark PB Gray SR Ferguson LD Anderson JJ Lyall DM Cleland JG Jhund PS Gill J MR Pell JP Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019，27，7： | 10 |
| 3 | Awareness of eye complications and prevalence of retinopathy in the first visit to eye clinic among type 2 diabetic patients显示文摘AIM:To assess the awareness of eye complications and the prevalence of retinopathy,in the first visit to eye clinic,among type 2 diabetic patients attending a tertiary medical centre in Kuala Lumpur,Malaysia.METHODS:An investigator-administered questionnaire was given to 137 patients with diabetes undergoing first time eye screening in the eye clinic.This was followed by a detailed fundus examination by a senior ophthalmologist to assess for presence of retinopathy.RESULTS:Almost 86% of respondents were aware of diabetic eye complications,especially in patients who had achieved tertiary educational level(96.3%).The majority of the patients(78.8%) were referred by their physicians and only 20.4% came on their own initiative.Many of the patients(43.8%) did not know how frequent they should go for an eye check-up and 72.3% did not know what treatments were available.Lack of understanding on diabetic eye diseases(68.6%) was the main barrier for most patients for not coming for eye screening earlier.Despite a high level of awareness,only 21.9% had recorded HbA1c level of <6.5% while 31.4% were under the erroneous assumption of having a good blood sugar control.A total of 29.2% had diabetic retinopathy in their first visit eye testing.CONCLUSION:In the present study,29.2% of type 2 diabetic patients had retinopathy in their first time eye testing.Although the awareness of diabetic eye complications was high among first time eye screening patients,the appropriate eye care-seeking behavior was comparatively less and should be rectified to prevent the rise of this sight threatening eye disease. | I Tajunisah PS Wong LT Tan P Rokiah SC Reddy | 2011 | International Journal of Ophthalmology(English edition)2011，4，5： | 3 |
| 4 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 5 | The pathology of hepatits C virus显示文摘 | Scheuer PS Ashrafzadeh P Sherlock S | 1992 | Hepatology1992，15，： | 1 |
| 6 | Structural similarity between the bone marrow extracellular matrix protein and neurokinin 1could be the limiting factor in the hematopoietic effects of substance P显示文摘 | Rameshwar P Gascon P Bandari PS | 2002 | Can J Physiol Pharmacol2002，80，5： | 1 |
| 7 | A prospective study of phryngocutaneous fistulas following total laryngectomy显示文摘 | Qureshi SS Chaturvedi P Pai PS | 2005 | J Cancer Res Ther2005，1，1： | 1 |
| 8 | A new model to understand the career choice and practice location decisions of medical graduates 显示文摘 | Stagg P Greenhill J Worley PS | 2009 | Rural and Remote Health 9 (online)2009，15，9： | 1 |
| 9 | Renal sympathetic denerva- tion for treatment of resistant hypertension: a systematic review显示文摘 | Gosain P Garimella PS Hart PD | 2013 | J Clin Hypertens (Greenwich)2013，15，1： | 1 |
| 10 | Protection by cyclosporin A of mitochondrial and cellular functions during a cold preservation-warm reperfusion of rat liver显示文摘 | Plin Cj Haddad PS Tillement J P | 2004 | Eur J Pharmacol2004，9，23： | 1 |
| 11 | Inflammatory response to percutaneous coronary intervention in stable coronary artery disease显示文摘 | Munk PS Breland UM Aukrust P | 2011 | J Thromb Thrombolysis2011，31，1： | 1 |
| 12 | Angiographic and clinical outcomes following acute infarct angioplasty on saphenous vein显示文摘 | Watson PS Hadjipetrou P Cox SV | 1999 | Am J Cardiol1999，83，7： | 1 |
| 13 | Enterovirus sequences resembling coxsackievirus A2 detected in stool and spleen from a girl with fatal myocarditis显示文摘 | Bendig JWA O'Brien PS Muir P | 2001 | J Med Virol2001，64，4： | 1 |
| 14 | Sequence of the 5, flanking region of CYP3A5:comparative analysis with CYP3 A4 and CYP3 A7 显示文摘 | Jounaidi Y Guzelian PS Maurel P | 1994 | B iochem Res Commun1994，205，： | 1 |
| 15 | The shang ring device for adult male circumcision:a proof of voncept study in kenya显示文摘 | Barone MA Masson P Li PS | 2011 | J Acquir Immune Defic Syndr2011，57，1： | 1 |
| 16 | Differences in retinol metabolism and proliferative response between neointimal and medial smooth muscle cells 显示文摘 | Gidlof AC Ocaya P Olofsson PS | 2006 | J Vasc Res2006，43，4： | 1 |
| 17 | Estimating the im- pact of stroke unit care in a whole population:an epidemiologi- cal study using routine data显示文摘 | Langhorne P Lewsey JD Jhund PS | 2010 | Journal of Neurology Neuro- surgery Psychiatry2010，81，12： | 1 |
| 18 | The role of complement in ocular pathology显示文摘 | Bora NS Jha P Bora PS | | 0，，： | 1 |
| 19 | 3D bone tissue engineered with bioactive microspheres in simulated microgravity显示文摘 | Qiu QQ Ducheyne P Ayyaswamy PS | | 0，，03： | 1 |
| 20 | Glycogen storage disease type III diagnosis and management guidelines显示文摘 | Kishnani PS Austin SL Arn P | 2010 | Genet Med2010，12，： | 1 |
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