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| 1 | Tongue coating microbiome as a potential biomarker for gastritis including precancerous cascade显示文摘The development of gastritis is associated with an increased risk of gastric cancer. Current invasive gastritis diagnostic methods are not suitable for monitoring progressIn this work based on 78 gastritis patients and 50 healthy individuals, we observed that the variation of tongue-coating microbiota was associated with the occurrenee and development of gastritis. Twenty-one microbial species were identified for differentiating tongue-coating microbiomes of gastritis and healthy individuals. Pathways such as microbial metabolism in diverse environments, biosynthesis of antibiotics and bacterial chemotaxis were up-regulated in gastritis patients. The abundance of Campylobacter concisus was found associated with the gastric precancerous cascade. Furthermore, Campylobacter concisus could be detected in tongue coating and gastric fluid in a validation cohort containing 38 gastritis patients. These observations provided biological evidence of tongue diagnosis in traditional Chinese medicine, and indicated that tongue-coating microbiome could be a potential non-invasive biomarker, which might be suitable for long-term monitoring of gastritis. | Jiaxing Cui Hongfei Cui Mingran Yang Shiyu Du Junfeng Li Yingxue Li Liyang Liu Xuegong Zhang Shao Li | 2019 | Protein & Cell2019，10，7： | 21 |
| 2 | Underwater Explosion Treatment of Marine Soft Foundation显示文摘The consolidation of soft foundation is a problem that commonly appears in harbor construction engineering on muddy coast. Introduced in this paper is the experimental study on underwater explosion treatment of soft foundation, including the regulations of explosion hollow development and medium movement, the law of similarity of densification and settlement of filled stone mass by shock wave pressure and explosion energy and their construction technologies, etc. A number of projects have been completed by applying this new technique, and the technique itself has been proved practicable. | Zheng, Zhemin Yang, Zhengsheng Jin, Liu | 1991 | China Ocean Engineering1991，6，2： | 16 |
| 3 | Altered oral microbiota in chronic hepatitis B patients with different tongue coatings显示文摘AIM To elucidate tongue coating microbiota and metabolic differences in chronic hepatitis B(CHB) patients with yellow or white tongue coatings.METHODS Tongue coating samples were collected from 53 CHBpatients(28 CHB yellow tongue coating patients and 25 CHB white tongue coating patients) and 22 healthy controls.Microbial DNA was extracted from the tongue samples,and the bacterial 16 S ribosomal RNA gene V3 region was amplified from all samples and sequenced with the Ion Torrent PGM^(TM)sequencing platform according to the standard protocols.The metabolites in the tongue coatings were evaluated using a liquid chromatographymass spectrometry(LC-MS) platform.Statistical analyses were then performed.RESULTS The relative compositions of the tongue coating microbiotas and metabolites in the CHB patients were significantly different from those of the healthy controls,but the tongue coating microbiota abundances and diversity levels were not significantly different.Compared with the CHB white tongue coating patients,the CHB yellow tongue coating patients had higher hepatitis B viral DNA(HBV-DNA) titers(median 21210 vs 500,respectively,P = 0.03) and a significantly lower level of Bacteroidetes(20.14% vs 27.93%,respectively,P = 0.013) and higher level of Proteobacteria(25.99% vs 18.17%,respectively,P = 0.045) in the microbial compositions at the phylum level.The inferred metagenomic pathways enriched in the CHB yellow tongue coating patients were mainly those involved in amino acid metabolism,which was consistent with the metabolic disorder.The abundances of bacteria from Bacteroidales at the order level were higher in the CHB white tongue coating patients(19.2% vs 27.22%,respectively,P = 0.011),whereas Neisseriales were enriched in the yellow tongue coating patients(21.85% vs 13.83%,respectively,P = 0.029).At the family level,the abundance of Neisseriaceae in the yellow tongue patients was positively correlated with the HBV-DNA level but negatively correlated with the S-adenosyl-L-methionine level.CONCLUSION This research illustrates specific clinical features and bacterial structures in CHB patients with different tongue coatings,which facilitates understanding of the traditional tongue diagnosis. | Yu Zhao Yu-Feng Mao Yi-Shuang Tang Ming-Zhu Ni Qiao-Hong Liu Yan Wang Qin Feng Jing-Hua Peng Yi-Yang Hu | 2018 | World Journal of Gastroenterology2018，24，30： | 13 |
| 4 | Black hairy tongue syndrome显示文摘Black hairy tongue(BHT) is a benign medical condition characterized by elongated filiform lingual papillae with typical carpet-like appearance of the dorsum of the tongue. Its prevalence varies geographically, typically ranging from 0.6% to 11.3%. Known predisposing factors include smoking, excessive coffee/black tea consumption, poor oral hygiene, trigeminal neuralgia, general debilitation, xerostomia, and medication use. Clinical presentation varies but is typically asymptomatic, although aesthetic concerns are common. Differential diagnosis includes pseudo-BHT, acanthosis nigricans, oral hairy leukoplakia, pigmented fungiform papillae of the tongue, and congenital melanocytic/melanotic nevi/macules. Clinical diagnosis relies on visual observation, detailed history taking, and occasionally microscopic evaluation. Treatment involves identification and discontinuation of the offending agent, modifications of chronic predisposing factors, patient's re-assurance to the benign nature of the condition, and maintenance of adequate oral hygiene with gentle debridement to promote desquamation. Complications of BHT(burning mouth syndrome, halitosis, nausea, gagging, dysgeusia) typically respond to therapy. Prognosis is excellent with treatment of underlying medical conditions. BHT remains an important medical condition which may result in additional burden on the patient and health care system and requires appropriate prevention, recognition and treatment. | Grigoriy E Gurvits Amy Tan | 2014 | World Journal of Gastroenterology2014，20，31： | 12 |
| 5 | The rule of sediment transport on the Nanhui tidal flat in the Changjiang Estuary显示文摘The Nanhui tidal flat is located in the area of slow current where the ebb currents from the Changjiang Estuaryand the Hangzhou Bay converge and the flood current from the sea diverges into the estuary and the bay. The flat extends seaward in tongue shape and has a wide and gentle surface with a marked difference of tidal levels on its two sides, which results in the sediment longitudinal transport on the flat. The water-sediment conditions are diverse at different locations. The velocity and sediment concentration in intertidal zone are higher during the flood tide than those during the ebb tide. The net sediment transport is landward, resulting in a large amount of deposition of sediments on the shoal. However, the ebb current is the dominant one in deep-water area where the net sediment transport is seaward. There exist two circulation systems in plane view on the shoal and in its adjacent deep-water area, which results in the sediment exchanges between the flat and channel and between the estuary | Li Jiufa Institute of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China | 1991 | Acta Oceanologica Sinica1991，10，1： | 10 |
| 6 | Burning mouth syndrome显示文摘Burning mouth syndrome is a debilitating medical condition affecting nearly 1.3 million of Americans.Its common features include a burning painful sensation in the mouth,often associated with dysgeusia and xerostomia,despite normal salivation.Classically, symptoms are better in the morning,worsen during the day and typically subside at night.Its etiology is largely multifactorial,and associated medical conditions may include gastrointestinal,urogenital,psychiatric,neurologic and metabolic disorders,as well as drug reactions.BMS has clear predisposition to peri-/post menopausal females.Its pathophysiology has not been fully elucidated and involves peripheral and central neuropathic pathways.Clinical diagnosis relies on careful history taking,physical examination and laboratory analysis.Treatment is often tedious and is aimed at correction of underlying medical conditions,supportive therapy,and behavioral feedback.Drug therapy with alpha lipoic acid,clonazepam,capsaicin,and antidepressants may provide symptom relief.Psychotherapy may be helpful.Short term follow up data is promising,however,long term prognosis with treatment is lacking.BMS remains an important medical condition which often places a recognizable burden on the patient and health care system and requires appropriate recognition and treatment. | Grigoriy E Gurvits Amy Tan | 2013 | World Journal of Gastroenterology2013，19，5： | 7 |
| 7 | 人体词“舌”和“tongue”语义转移的认知构架显示文摘人体词'舌',对应英文词'tongue',在漫长的语言演变过程中,主要借助隐喻和转喻的作用,其语义均由原型义延伸变化,产生了如下义项:基于突显和邻近原则的'言语'、'性格'、'情感'转喻所指;基于形貌相似的'舌状物'隐喻所指;基于隐喻转喻互动的'实体'隐转喻所指。上述语义转移是一个以辐射型为主、连锁型为辅的综合型过程,其中'功能特征'是主要的词义取象源。数据统计表明'tongue'功能表达要多于'舌'。 | 赵学德 王晴 | 2011 | 长沙大学学报2011，25，6： | 6 |
| 8 | 英语外来词——英语词源学初探显示文摘作为一种接近于国际通用语言的英语,其显著特征之一,是它拥有世界上任何其他语言所不能比拟的、极其丰富的外来词。这无数的外来词给英语增添了新鲜的血液,使英语在表达各种复杂事物与现象时,更加鲜明、确切,更具有修辞色彩。权威学者曾估计,在英语约50万词的总词汇量中,外来词约占70%。为何外来词在英语总词汇量中占如此大的比例?这只能从英语词源学的角度去探求答案。 | 盛培林 | 1990 | 温州大学学报(自然科学版)1990，，4： | 4 |
| 9 | Analysis of DNA Methylation Level by Methylation-Sensitive Amplification Polymorphism in Half Smooth Tongue Sole(Cynoglossus semilaevis)Subjected to Salinity Stress显示文摘Increasingly arisen environmental constraints may contribute to heritable phenotypic variation including methylation changes,which can help the animals with development,growth and survival.In this study,we assessed the DNA methylation levels in three tissues(gonad,kidney and gill) of half smooth tongue sole under the salinity stress.The methylation-sensitive amplification polymorphism(MSAP) technique was applied to illustrate the regulation of epigenetic mechanism in environmental stimuli.Fish were subjected to 15 salinity treatment for 7 and 60 days,respectively.A total of 11259 fragments were amplified with 8 pairs of selective primers.The levels of methylated DNA in different tissues of females and males without salinity stress were analyzed,which were 32.76% and 47.32% in gonad;38.13% and 37.69% in kidney;37.58% and 34.96% in gill,respectively.In addition,the significant difference was observed in gonad between females and males,indicating that discrepant regulation in gonadal development and differentiation may involve sex-related genes.Further analysis showed that total and hemi-methylation were significantly decreased under 15 salinity for 7 days,probably resulting in up-regulating salt-tolerance genes expression to adjust salt changing.With the adjustment for 60 days,total and hemi-methylation prominently went back to its normal levels to obtain equilibrium.Particularly,full methylation levels were steady along with salinity stress to maintain the stability of gene expression.Additionally,the data showed that gonads in females and gills in males were superior in adaptability.As a result,DNA methylation regulates tissue-specific epiloci,and may respond to salinity stress by regulating gene expression to maintain animal survival and activity. | LI Siping HE Feng WEN Haishen LI Jifang SI Yufeng LIU Mingyuan HE Huiwen HUANG Zhengju | 2017 | Journal of Ocean University of China2017，16，2： | 4 |
| 10 | Ultra-Short Pulsed Laser Manufacturing and Surface Processing of Microdevices显示文摘Ultra-short laser pulses possess many advantages for materials processing.Ultrafast laser has a significantly low thermal effect on the areas surrounding the focal point;therefore,it is a promising tool for micro-and submicro-sized precision processing.In addition,the nonlinear multiphoton absorption phenomenon of focused ultra-short pulses provides a promising method for the fabrication of various structures on transparent material,such as glass and transparent polymers.A laser direct writing process was applied in the fabrication of high-performance three-dimensional(3D)structured multilayer microsupercapacitors(MSCs)on polymer substrates exhibiting a peak specific capacitance of 42.6 mF·cm^-2 at a current density of 0.1 mA·cm^-12.Furthermore,a flexible smart sensor array on a polymer substrate was fabricated for multi-flavor detection.Different surface treatments such as gold plating,reducedgraphene oxide(rGO)coating,and polyaniline(PANI)coating were accomplished for different measurement units.By applying principal component analysis(PCA),this sensing system showed a promising result for flavor detection.In addition,two-dimensional(2D)periodic metal nanostructures inside 3D glass microfluidic channels were developed by all-femtosecond-laser processing for real-time surfaceenhanced Raman spectroscopy(SERS).The processing mechanisms included laser ablation,laser reduction,and laser-induced surface nano-engineering.These works demonstrate the attractive potential of ultra-short pulsed laser for surface precision manufacturing. | Yongchao Yu Shi Bai Shutong Wang Anming Hu | 2018 | Engineering2018，4，6： | 4 |
| 11 | Simulation of volute tongue of small-size centrifugal compressor显示文摘A high speed and small mass-flow-rate centrifugal compressor with original and modified volute tongue shape was simulated by 3D viscous Navier-Stokes equations.A sharp and a round tongue of volute were modeled to compare their pressure ratios and efficiency characteristics.The flow fields around volute tongues were investigated;the velocity and pressure distributions of volute inlet were studied by unsteady simulation.Static pressure fluctuation near volute tongue was monitored and transformed into amplitude spectrum to identify blade passing frequency influence.The results show that the tongue simplification can cause certain difference on pressure ratio and efficiency.The pressure and velocity distribution of volute inlet indicate obvious circumferential distortion due to volute tongue especially at low mass flow rate.In addition,the static pressure pulsation of volute inlet and the noise level in diffuser and volute increase significantly under low mass flow operating condition. | 李杜 杨策 周密 陈山 | 2011 | Journal of Beijing Institute of Technology2011，20，4： | 4 |
| 12 | Deep lingual arterial chemoembolization of tongue carcinoma with microcapsuled anticancer drug显示文摘Objective: Microcapsule chemoembolism is a promising treatment of tumors. We describe a deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum. Methods: Lingual artery cast specimens from cadavers were microscopically examined, and 78 patients with tongue cancer were recruited and treated with the deep lingual arterial embolization therapy. Results: Microcapsule embolism occurred approximately at the fifth or sixth level of the deep lingual artery branches. The five-year survival rate was 88.5% (69 out of 78), and the ten-year survival rate 52.6% (41 out of 78). Conclusion: The deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum is an effective therapy to treat carcinoma in mid-margin or mid-body of the tongue. | HE Hong1, HUANG Jian-qi1, PING Fei-yun1, CHEN Guan-fu1, ZHANG Su-zhan2 (1Department of Stomatology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China) (2Cancer Institute, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China) | 2007 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2007，8，10： | 3 |
| 13 | MiR-25-3p attenuates the proliferation of tongue squamous cell carcinoma cell line Tca8113显示文摘Objective:To investigate the effects of miR-25-3p on the occurrence,development and proliferation of tongue squamous cell carcinoma cells.Methods:To establish tongue squamous cell carcinoma cell line Tca8113 that stably and highly express miR-25-3p using recombinant reiroviral vector-mediated gene transfer method.The proliferation of transfected Tca8113 was detected by thiazolyl blue tetrazolium bromide(MTT)and cell colony formation assays.eyclnD1,p21^(cipt)and p27^(kipt)mRNA expressions in the transfected Tca-8113 were detected by quantitative PCR.cyclinD1,p21^(cipt),p27^(kipt),AKT,p-AKT,FOXOt and p-FOX01 expressions in the transfected Tca8113 were detected by western blot analysis.In addition,miR-25-3p expression in the tongue squamous cell carcinoma cell line and tissue specimen was also detected by quantitative PCR.Results:Quantitative PCR showed that mitt-25-3p expression in the tongue squamous cell carcinoma cell lines and tissue specimen was significantly lower than that in the adjacent tissue.MTT and cell colony formation assays showed that after miR-25-3p overexpression,the proliferation of transfected Tca8113 was obviously attenuated.Western blot analysis and quantitative PCR showed that after miR-25-3p overexpression.p21^(cipt)and p27^(kipt)expressions were upregulated,while cyclinD1,AKT,FOXO1 expressions were downregulated,and AKT and FOXO1 phosphorylation was inactivated in the transfected Tca8113 cells.Conclusions:MiR-25-3p inhibited the proliferation of tongue squamous cell carcinoma cells and regulated cell cycle-related protein expression,playing an important role in the occurrence and development of squamous cell carcinoma of the tongue. | Jia-Ying Xu Li-Li Yang Chao Ma Yuan-Liang Huang Gui-Xiang Zhu Qi-Lin Chen | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，9： | 3 |
| 14 | 文化差异(英文) | 吴昕 | 2004 | 师范教育2004，0，2： | 3 |
| 15 | 英语“移就”辞格的探讨显示文摘“移就”是汉语修辞学中设立较早的一个辞格。在汉语的言语语活动中,“将描写甲事物性状的词语移用来描写乙事物性状,这种词语活用叫‘移就’”。(《修辞》、倪宝元著,十九八○浙江人民出版社出版,九十五页。》无独有偶,英语中也有大量这种“词语活用”的语言现象,并且有定名——hgpallage。但是,国内外一般中小型辞典都未收录hypallage一词,而收有hypallage一词的某些辞典对该词却有两种不同的界说,一种界说认为hypallage指“格的转换”,国内学者将其译为“换置法”。另一种界说认为hypallage指:“ | 熊木清 | 1986 | 怀化学院学报1986，0，3： | 2 |
| 16 | 试谈英语误用词的汉译显示文摘何为 Malapropism,拙著“Malapropism 探微”(载《现代外语》1988年第三期)已经论及,本文不再赘述。英汉两种语言文字在音、形、义方面的明显差异给 Malapropism 的汉译带来了巨大的困难,因为 | 覃先美 | 1991 | 山东外语教学1991，12，1： | 2 |
| 17 | 浅谈陕北民歌歌词中常用修辞格的英译显示文摘1.引言 陕北民歌最能代表陕北的风韵和特色,被誉为中华民族音乐殿堂里的"音乐活化石",也受到越来越多人的关注和喜爱。陕北民歌歌词句式多变,有多样化修辞格的使用。本文选取王宏印教授的译作《西北回响》以及其他几篇为数不多的相关翻译研究作品作为语料,分析陕北民歌歌词中常用修辞格的英译,为陕北民歌走向世界作出贡献。 | 李珊珊 | 2016 | 文学教育2016，，10： | 2 |
| 18 | Correlation analysis between characteristics under gastroscope and image information of tongue in patients with chronic gastritis显示文摘OBJECTIVE:To explore the correlation between diagnostic information of tongue and gastroscopy results of patients with chronic gastritis.METHODS:Frequent pattern growth(FP-Growth),SPSS Modeler was used to analyze the correlation rules between the image information of tongue parameters and the characteristics of the stomach and duodenum seen under gastroscopy.RESULTS:Ranking in order of confidence:cyanotic tongue,slippery fur,yellow fur and spotted tongue were sequently associated with both gastric antrum mucosal hyperemia or edema and gastric antrum mucosal erythema/macula.L,one value of tongue coating color,which counted among(30,60),tooth-marked tongue and b,one value of tongue coating color,which counted in the range of(5,20)were sequently associated with gastric antrum mucosal erythema/macula.A,one value of tongue body color,which counted in the range of(0,20),was related to both gastric antrum mucosal hyperemia or edema and gastric antrum mucosal erythema/macula.a,one value of tongue coating color,which counted in the range of(15,35),was associated with gastric antrum mucosal erythema/macula.There are a total of 9 strong correlation rules.CONCLUSIONS:Cyanotic tongue,slippery fur,yellow fur,the CIE Lab value of tongue coating,a,the value of tongue body color,spotted tongue,and tooth-marked tongue are all related to the gastric antrum mucosal hyperemia or edema and gastric antrum mucosal erythema/macula.The conditions of gastric mucosa could be predicted by the examination of the above related image information of tongue. | SHANG Zimeng DU Zhengguang GUAN Bei JI Xingyu CHEN Longchang WANG Yongji MA Yun | 2022 | Journal of Traditional Chinese Medicine2022，42，1： | 2 |
| 19 | Existence, morphology and structure of the Yellow Sea Warm Current Branch approaching waters offshore Qingdao, China显示文摘In this study, we focused on full-region cruise survey data, near-bottom continuous mooring observations and sea surface wind products from the western South Yellow Sea in winter; after ensuring the data reliability and accuracy, we processed and analyzed the data. Image resolution experiments were carried out to determine the lowest recognition resolutions for all image types, which represent the resolution characteristics of the data. The existence of a warm water tongue originating from the Yellow Sea Warm Current(YSWC) that approached waters offshore Qingdao was confirmed. For the first time, a high salinity water tongue, corresponding to the warm water tongue, was described and found to be more representative of the YSWC branch path. This warm tongue is a sign of the branch originating from the YSWC, which we defined as the Yellow Sea Warm Current Branch approaching waters offshore Qingdao(YSWC-QDB). The pattern of the warm and salty water tongues showed remarkable rear, branching middle, shrinking neck and expanding top regions. These patterns showed a temporal feature of the tongues, and were the result of multi-temporal branches in front of the YSWC main section as well as the YSWC-QDB crossing the southwestward path of the extension of the North Shandong Coastal Current flowing along the southeast coast of the Shandong Peninsula(NSCC-SESE). Analysis using mooring data at a sensitive and representative station also showed the existence of the YSWC-QDB. It is a probabilistic event that manifests as a northwestward flow that decreases gradually from the bottom to the surface in the early cold air transit stage and consistent in the whole water column profile in the later stage. It varies quasi-periodically with weather processes. It also transports some of the YSWC water stored in the entrance area of the Bohai and Yellow seas under winter wind conditions to the western South Yellow Sea as a compensatory current. This current, caused by northerly winds, especially northwest winds and obstruction of the NSCC-SESE, was present, and strong water reduction and compensation caused significant residual sea level oscillations. The compensatory current, if caused by strong northwest wind,began to appear when its direction was opposite to the wind direction. In addition, confirmation of the YSWC-QDB provides an oceanographic basis for the short cooling time and rapid warming in the Qingdao area in winter. This research provides a basis for further studies of the YSWC-QDB at high spatial and temporal resolutions using large sea surface datasets. For monsoon basin dynamics, this study can also be extended to the whole Bohai and Yellow seas and closed or semi-closed basins on the continental margin. | Xuejun XIONG Xiaomin HU Yanliang GUO Long YU Liang CHEN Yuhuan XUE | 2019 | Science China Earth Sciences2019，62，7： | 2 |
| 20 | Study on Fat and Thin Analysis of Tongue Body Based on Two- Dimensional Ultrasonic Imaging显示文摘In the development of traditional Chinese medicine in China for fi ve thousand years, the tongue clinic occupies a very important position. In Chinese medicine, it is an irreplaceable role in the diagnosis and treatment of Chinese medicine of important method. Tongue diagnosis as one of the most characteristic of Chinese medicine diagnosis has been from the previous subjective observation, relying on the experience to judge the era into the new era of tongue diagnosis objectifi cation, quantifi cation, and the introduction of computer digital image processing technology to more Accurate diagnosis. This article will mainly introduce the current in the Chinese and Western medicine on all aspects of the tongue diagnosis of the objective, micro, quantitative progress, the characteristics of tongue images and a variety of processing techniques, including tongue image automatic segmentation, and tongue fat and thin The Relationship and Modernization of Organ Pathology in Viscera. At the same time, a tongue-sized measurement method is introduced. Two-dimensional ultrasound imaging is used as a means of inspection to establish a set of ultrasonic tongue-sized measurement methods. The measured parameters include the two longitudinal planes of the tongue and the crosssection of the tongue. Out of the tongue size of the data, the overall analysis of the size of the tongue shape. This method combines some of the confi guration line spacing, area, and circumference measurement functions to directly measure the data. Finally, through the accuracy test of the measurement method, it is proved that the measurement result of tongue two-dimensional ultrasound imaging is accurate. All the eff orts of modernization are committed to the Chinese medicine tongue medicine to scientifi c can be quantifi ed;Chinese medicine tongue diagnosis will also make a greater contribution to modern medicine. | Yanguo Hu Yaying Zhao Dean Fu | 2018 | Medical Imaging Process & Technology2018，1，1： | 2 |
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