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| 1 | Real-life chromoendoscopy for dysplasia surveillance in ulcerative colitis显示文摘AIM To evaluate the use of chromoendoscopy for surveillance of ulcerative colitis in a real-life community hospital setting.METHODS Patients with extensive ulcerative colitis, having disease duration of more than 8 years and who presented between the years of 1999 to 2013, were offered enrolment in this single cohort prospective study. All participants underwent standard bowel preparation with sodium phosphate and chromoendoscopy. Two expert endoscopists, novice to chromoendoscopy, evaluated each segment of the colon with standarddefinition colonoscopes after spray application of 0.4% indigo carmine. All observed lesions were recorded and evaluated before being removed and/or biopsied. In addition, nontargeted biopsies were taken from each segment of the colon. The dysplasia detection rate and dysplasia detection yield were ascertained. RESULTS A total of 21 neoplastic lesions(2 carcinomas, 4 of high-grade dysplasia and 15 of low-grade dysplasia) and 27 nondysplastic lesions were detected in 16 of the total 67 patients(70% male; median disease duration: 17 years; median age at diagnosis: 25 years; 92% aminosalicylate-treated). The dysplasia detection rate was 10.5%(7/67 patients). The dysplasia detection yield was 20.8%(10/48) for targeted biopsies and 3.5%(11/318) for nontargeted biopsies. The sensitivity and specificity for the macroscopic evaluation of neoplasia using chromoendoscopy were 48% [95% confidence interval(CI): 26%-70%] and 96%(95%CI: 93%-98%), respectively. The positive predictive and negative predictive values were 42%(95%CI: 27%-59%) and 97%(95%CI: 95%-98%), respectively. A total of 19/21 dysplastic lesions were detected in mucosa with histologic inflammation.CONCLUSION Chromoendoscopy seems to be of value for dysplasia surveillance of ulcerative colitis in a community hospital setting. The yield of non-targeted biopsies is negligible. | Pasquale Klepp Anita Tollisen Arne Roseth Milada Cvancarova Smastuen Solveig N Andersen Morten Vatn Bjorn A Moum Stephan Brackmann | 2018 | World Journal of Gastroenterology2018，24，35： | 3 |
| 2 | A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection显示文摘 | Luca Formichella Laura Romberg Christian Bolz Michael Vieth Michael Geppert Gereon G?ttner Christina N?lting Dirk Walter Wolfgang Schepp Arne Schneider Kurt Ulm Petra Wolf Dirk H. Busch Erwin Soutschek Markus Gerhard | 2013 | Clinical and Vaccine Immunology2013，，11： | 2 |
| 3 | Test of experimental set-ups for electrodialytic removal of Ca, Zn, Pb and Cd from different contaminated harbour sediments显示文摘 | GUNVOR M N LISBETH M O ARNE V | 2005 | Engineering Geology2005，77，： | 1 |
| 4 | Test of experimental setups for electrodialytic removal of Cu,Zn,Pb and Cd from differentcontaminated harbour sediments显示文摘 | GUNVOR M N LISBETH M O ARNE V | 2005 | Engineering Geology2005，77，3： | 1 |
| 5 | Decision-directed coherent detection in multicarrier systems on Rayleigh fading channels显示文摘 | FRENGER P K ARNE N SVENSSON B | 1999 | IEEE Transactions on Vehicular Technology1999，48，2： | 1 |
| 6 | Development of the as-cast microstructure in magnesium-aluminium alloys 显示文摘 | ARNE K D YOUNG C L MARK D N | 2001 | Journal of Light Metals2001，，1： | 1 |
| 7 | Long distance running increases plantar pressures beneath the metatarsal heads: A barefoot walking investigation of 200 marathon runners显示文摘 | Arne N Frauke F Carolin K | 2008 | Gait Posture2008，27，1： | 1 |
| 8 | Supercriticalfluid extraction of free amino acids from broccoli leaves显示文摘 | E Arn a iz J Bernal M T Mart i n | 2012 | Journal of Chromatography A2012，1250，： | 1 |
| 9 | Loss of expression of MLH1,MSH2, MSH6, and PTEN related to endometrial cancer in 68 patients with endometrial hyperplasia 显示文摘 | Orbo A Nilsen M N Arnes M S | 2003 | Int J Gynecol Pathol2003，22，2： | 1 |
| 10 | Devel-opment of the As-cast Microstrucure in Magnesium-aluminium-Alloys显示文摘 | Arne K D Young C L Mark D N | 2001 | Journal of Light Metals2001，，1： | 1 |
| 11 | Social exploitation of vitellogenin显示文摘 | Gro VA Kari N Arne H | 2003 | Proceeding of the National Academy of Scienses of the United States of America2003，100，： | 1 |
| 12 | Characterisation of the 5' integration site and development of an event-specific real-time PCR assay for NK603 maize from a low starting copy number显示文摘 | Christer R N Kunt G B Arne H J | 2004 | European Food Research and Technology2004，219，： | 1 |
| 13 | Timing of gold mineralization in western and central Victoria, Australia: New con- straints from SHRIMP Ⅱ analysis of zircon grains from felsic intrusive rocks显示文摘 | Arne D C Bierlein F P McNaughton N | 1998 | Ore Geology Reviews1998，13，： | 1 |
| 14 | Obtaining the three-dimensional structure of tree orchards from remote 2D terrestrial LIDAR scanning显示文摘 | Joan R. Rosell Jordi Llorens Ricardo Sanz Jaume Arnó Manel Ribes-Dasi Joan Masip Alexandre Escolà Ferran Camp Francesc Solanelles Felip Gràcia Emilio Gil Luis Val Santiago Planas Jordi Palacín | 2009 | Agricultural and Forest Meteorology2009，，9： | 1 |
| 15 | A tractor-mounted scanning LIDAR for the non-destructive measurement of vegetative volume and surface area of tree-row plantations: A comparison with conventional destructive measurements显示文摘 | Joan Ramon Rosell Polo Ricardo Sanz Jordi Llorens Jaume Arnó Alexandre Escolà Manel Ribes-Dasi Joan Masip Ferran Camp Felip Gràcia Francesc Solanelles Tomàs Pallejà Luis Val Santiago Planas Emilio Gil Jordi Palacín | 2008 | Biosystems Engineering2008，，2： | 1 |
| 16 | Extracorporeal shock waves,a new non-surgical method to treat severe burns显示文摘 | Arnó A García O Hernán I | | 0，，06： | 1 |
| 17 | Immune responses in the skin in old age显示文摘 | Milica Vukmanovic-Stejic Malcolm HA Rustin Janko Nikolich-Zugich Arne N Akbar | 2011 | Current Opinion in Immunology2011，，4： | 1 |
| 18 | Herbivore benefits from vectoring plant virus through reduction of period of vulnerability to predation显示文摘 | Belén Belliure Arne Janssen Maurice W. Sabelis | 2008 | Oecologia2008，，4： | 1 |
| 19 | Characterisation of the 5′ integration site and development of an event-specific real-time PCR assay for NK603 maize from a low starting copy number显示文摘 | CHRISTER R N KUNT G B ARNE H J | 2004 | European Food Research and Technology2004，219，： | 1 |
| 20 | Delay-based congestion avoidance for TCP显示文摘 | JIM M ARNE N INJONG R | 2003 | IEEE/ACM Transactions On Networking2003，11，3： | 1 |
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