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| 1 | Diagnosis of Helicobacter pylori : What should be the gold standard?显示文摘Since the discovery of Helicobacter pylori(H. pylori) in 1983, numerous detection methods for the presence of the bacterium have been developed. Each one of them has been associated with advantages and disadvantages. Noninvasive tests such as serology, 13 C urea breath test(UBT) and stool antigen tests are usually preferred by the clinicians. Serology has its own limitation especially in endemic areas while 13 C UBT is technically very demanding. The stool antigen detection method, although specific, is usually associated with poor sensitivity. The 13 C UBT is believed to be specific, but with present revelation of the fact that stomach is colonized by many other urease producing bacteria makes it questionable. Histology, culture, rapid urease test and polymerase chain reaction(PCR) are the tests which are carried out on antral biopsies collected by invasive means. Histology has been proposed to be very sensitive and specific but the question is how by simply looking the morphology of the bacteria in the microscope, one can claim that the curved bacterium is exclusively H. pylori. Rapid urease test(RUT), the doctor's test, is also challenged because the presence of other urease producing bacteria in the stomach cannot be denied. Moreover, RUT has been reported with poor sensitivity specially, when density of the bacterium is low. Isolation of H. pylori is essential to investigate its growth requirements, antibiotic susceptibility testing, studying virulence factor to develop vaccine and many more explorations. It has also got several disadvantages i.e., special condition for transporting, media, incubation and few days waiting for the colonies to appear, apart from the speed essentially needed to process the specimens. Till date, majority of the microbiological laboratories in the world are not equipped and trained to isolate such fastidious bacterium. The option left is PCR methods to detect H. pylori 's DNA in gastric mucosa, gastric juice, saliva, dental plaques and environmental specimens. There are speculations for false positivity due to detection of non-pylori Helicobacters due to genetic sharing; and false negativity due to low bacterial counts and presence of PCR inhibitors. However, specimen collection, transportation and processing do not require speed and special conditions. PCR based diagnosis may be considered as gold standard by designing primers extremely specific to H. pylori and targeting at least more than one conserved genes. Similarly specificity of PCR may be improved by use of internal Primers. Further, nested PCR will take care of false negatives by countering the effect of PCR inhibitors and low bacterial counts. Therefore, nested PCR based methods if performed properly, may be proposed as gold standard test. | Saurabh Kumar Patel Chandra Bhan Pratap Ashok Kumar Jain Anil Kumar Gulati Gopal Nath | 2014 | World Journal of Gastroenterology2014，20，36： | 30 |
| 2 | Nonunion of coronal shear fracture of femoral condyle显示文摘大腿骨的髁的孤立的花冠破裂在成年人是稀罕的并且 Hoffa 骨折不属于工会被报导仅仅在文学的一些时间。我们分析了六个案例在三年的一个时期上的 Hoffa 破裂不属于工会。三个病人保存地被对待,三个病人有固定失败。表示的延期是到一年的 2 个月。治疗协议与膝 arthrolysis 一起由开的减小, pseudoarthrosis 的切除,骨头 grafting 和内部固定组成了。联合在平均数 16 星期在所有病人被完成。治疗 Hoffa 破裂不属于工会要求小心的外科手术前的计划和过细的外科的技术。关于在破裂管理和外科的技术的争吵的文学被考察。 | Ajay Pal Singh Ish Kumar Dhammi Raju Vaishya Anil Kumar Jain Arun Pal Singh Prashant Modi | 2011 | Chinese Journal of Traumatology2011，14，3： | 11 |
| 3 | All ileo-cecal ulcers are not Crohn's:Changing perspectives of symptomatic ileocecal ulcers显示文摘AIM To investigated clinical,endoscopic and histopathological parameters of the patients presenting with ileocecal ulcers on colonoscopy.METHODS Consecutive symptomatic patients undergoing colonoscopy,and diagnosed to have ulcerations in the ileocecal(I/C) region,were enrolled.Biopsy was obtained and theirclinical presentation and outcome were recorded.RESULTS Out of 1632 colonoscopies,104 patients had ulcerations in the I/C region and were included in the study.Their median age was 44.5 years and 59% were males.The predominant presentation was lower GI bleed(55,53%),pain abdomen ± diarrhea(36,35%),fever(32,31%),and diarrhea alone(9,9%).On colonoscopy,terminal ileum was entered in 96(92%) cases.The distribution of ulcers was as follows:Ileum alone 40%(38/96),cecum alone 33%(32/96),and both ileum plus cecum 27%(26/96).The ulcers were multiple in 98% and in 34% there were additional ulcers elsewhere in colon.Based on clinical presentation and investigations,the etiology of ulcers was classified into infective causes(43%) and noninfective causes(57%).Fourteen patients(13%) were diagnosed to have Crohn's disease(CD).CONCLUSION Non-specific ileocecal ulcers are most common ulcers seen in ileo-cecal region.And if all infections are clubbed together then infection is the most common(> 40%) cause of ulcerations of the I/C region.Cecal involvement and fever are important clues to infective cause.On the contrary CD account for only 13% cases as a cause of ileo-cecalulcers.So all symptomatic patients with I/C ulcers on colonoscopy are not Crohn's. | Jay Toshniwal Romesh Chawlani Amit Thawrani Rajesh Sharma Anil Arora Hardik L Kotecha Mohan Goyal Vijendra Kirnake Pankaj Jain Pankaj Tyagi Naresh Bansal Munish Sachdeva Piyush Ranjan Mandhir Kumar Praveen Sharma Vikas Singla Rinkesh Bansal Vineet Shah Sunita Bhalla Ashish Kumar | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，7： | 5 |
| 4 | Neglected isolated fracture of the trochlea humeri显示文摘 | Ajay Pal Singh Ish Kumar Dhammi Anil Kumar Jain Saurabh Jain | 2010 | Chinese Journal of Traumatology2010，13，4： | 4 |
| 5 | Monteggia fracture dislocation equivalents analysis of eighteen cases treated by open reduction and internal fixation显示文摘 | Ajay Pal Singh Ish Kumar Dhammi Anil Kumar Jain Rajeev Raman Prashant Modi | 2011 | Chinese Journal of Traumatology2011，14，4： | 4 |
| 6 | 显示文摘 | Kumar Anil Jain A K | 2003 | Journal of Photochemistry and Photobiology A: Chemistry2003，156，： | 1 |
| 7 | Chemical and biochemical transformations in ionic liquids显示文摘 | Nidhi Jain Anil Kumar Sushma Chauhan | 2005 | Tetrahedron2005，61，5： | 1 |
| 8 | Elbow dislocation with ipsilateral diaphyseal fractures of radius and ulna in an adult is it type 1 or type 2 Monteggia equivalent lesion?显示文摘 | Prashant Modi Ish Kumar Dhammi Ashish Rustagi Anil K Jain | 2012 | Chinese Journal of Traumatology2012，15，5： | 1 |
| 9 | Photophysics and photochemistry of colloidal CdS-TiO2 coupled semiconductors-Photocatalytic oxidation of indole 显示文摘 | ANIL KUMAR ARVIND KUMAR JAIN | 2001 | Journal of Molecular Catalysis2001，，165： | 1 |
| 10 | Chemical and biochemical transformations in ionic liquids 显示文摘 | Nidhi Jain Anil Kumar Sushma Chauhan | 2005 | Tetrahedron2005，61，5： | 1 |
| 11 | Vascular complications after percutaneous nephrolithotomy: Are there any predictive factors?显示文摘 | Aneesh Srivastava Kamal Jeet Singh Amit Suri Deepak Dubey Anant Kumar Rakesh Kapoor Anil Mandhani Sunil Jain | 2005 | Urology2005，，1： | 1 |
| 12 | Instrumented stabilization in spinal tuberculosis显示文摘 | Anil Kumar Jain Saurabh Jain | 2012 | International Orthopaedics2012，，2： | 1 |
| 13 | Hemical and bio-chemical transformations in ionic liauids 显示文摘 | Nidhi Jain Anil Kumar Sushma Chauhan | 2005 | Tetrahedron2005，61，： | 1 |
| 14 | The Indian National Association for Study of the Liver (INASL) Consensus on Prevention, Diagnosis and Management of Hepatocellular Carcinoma in India: The Puri Recommendations显示文摘 | Ashish Kumar Subrat K. Acharya Shivaram P. Singh Vivek A. Saraswat Anil Arora Ajay Duseja Mahesh K. Goenka Deepali Jain Premashish Kar Manoj Kumar Vinay Kumaran Kunisshery M. Mohandas Dipanjan Panda Shashi B. Paul Jeyamani Ramachandran Hariharan Ramesh Pa | 2014 | Journal of Clinical and Experimental Hepatology2014，，： | 1 |
| 15 | Chemical and bio- chemical transformations in ionic liquids 显示文摘 | Jain N Anil Kumar Chauhan S | 2005 | Tetrahedron Lett2005，61，： | 1 |
| 16 | Posttraumatic progressive cubitus varus deformity managed by lateral column shortening: A novel surgical technique显示文摘有转动的前臂的肘的外面的作成角是肘脉内翻足畸形。这畸形经常在 5-8 年的儿科学的年龄组被看作肱骨的 malunited supracondylar 骨折的 sequelae。畸形通常是非进步的,但是在在肱骨的中间的髁的 physeal 损害或先天的多骨的酒吧形成的情况下,畸形是进步的并且能在外观可笑。截骨术的各种各样的类型为标准非进步的肘脉内翻足畸形被定义,当多重手术为进步畸形被要求直到骨胳的成熟时。在这研究,我们在有可笑的进步肘脉内翻足畸形的 5 岁男孩描述了远侧的肱骨的一条新奇外科的途径和截骨术,完成好外科的结果。 | Amit Srivastava Anil Kumar Jain Ish Kumar Dhammi Rehan UI Haq | 2016 | Chinese Journal of Traumatology2016，19，4： | 0 |
| 17 | Neglected reverse Essex-Lopresti injury with ulnar nerve compression显示文摘45 岁女人作为有光线的头脱臼和远侧的半径折断的 anteromedial 被诊断在她右前臂上的损害以后的五个月。光线的头脱臼导致了尺骨的神经压缩。她有她的肘运动的严重限制。她与 arthrolysis,尺骨的神经的解压缩和光线的头切除术被对待。反向的艾塞克斯 Lopresti 损害和压缩尺骨的神经的光线的头脱臼没就我们的知识而言在英语语言文学被报导。机制为损害被建议。在尖锐演讲,桡尺骨的关节应该被做并且忽视的两个的恢复如此的损害的自然导致非最优的结果。 | Ajay Pal Singh Ish Kumar Dhammi Anil Kumar Jain | 2011 | Chinese Journal of Traumatology2011，14，2： | 0 |
| 18 | Recharge and vulnerability assessment of groundwater resources in North west India:Insights from isotope-geospatial modelling approach显示文摘Recent studies indicate dwindling groundwater quantity and quality of the largest regional aquifer system in North West India,raising concern over freshwater availability to about 182 million population residing in this region.Widespread agricultural activities have resulted severe groundwater pollution in this area,demanding a systematic vulnerability assessment for proactive measures.Conventional vulnerability assessment models encounter drawbacks due to subjectivity,complexity,data-prerequisites,and spatial-temporal constraints.This study incorporates isotopic information into a weighted-overlay framework to overcome the above-mentioned limitations and proposes a novel vulnerability assessment model.The isotope methodology provides crucial insights on groundwater recharge mechanisms(18O and 2H)and dynamics(3H)-often ignored in vulnerability assessment.Isotopic characterisation of precipitation helped in establishing Local Meteoric Water Line(LMWL)as well as inferring contrasting recharge mechanisms operating in different aquifers.Shallow aquifer(depth<60 m)showed significant evaporative signature with evaporation loss accounting up to 18.04%based on Rayleigh distillation equations.Inter-aquifer connections were apparent from Kernel Density Estimate(KDE)and isotope correlations.A weighted overlay isotope-geospatial model was developed combining 18O,3H,aquifer permeability,and water level data.The central and northern parts of study area fall under least(0.29%)and extremely(1.79%)vulnerable zones respectively,while majority of the study area fall under moderate(42.71%)and highly vulnerable zones(55.20%).Model validation was performed using groundwater NO3-concentration,which showed an overall accuracy up to 82%.Monte Carlo Simulation(MCS)was performed for sensitivity analysis and permeability was found to be the most sensitive input parameter,followed by 3H,18O,and water level.Comparing the vulnerability map with Land Use Land Cover(LULC)and population density maps helped in precisely identifying the high-risk sites,warranting a prompt attention.The model developed in this study integrates isotopic information with vulnerability assessment and resulted in model output with good accuracy,scientific basis,and widespread relevance,which highlights its crucial role in formulating proactive water resource management plans,especially in less explored data-scarce locations. | Annadasankar Roy Sitangshu Chatterjee Uday Kumar Sinha Anil Kumar Jain Hemant Mohokar Ajay Jaryal Tirumalesh Keesari Harish Jagat Pant | 2024 | Geoscience Frontiers2024，15，1： | 0 |
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