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| 1 | 17β-estradiol promotes recovery after myocardial infarction by enhancing homing and angiogenic capacity of bone marrow-derived endothelial progenitor cells through ERa-SDF-1/ CXCR4 crosstalking显示文摘17β-estradiol (E2)has been shown to mediate endothelial progenitor cells (EPCs)to repair infarcted myocardium.Both.estrogen receptor α(ERα)and stromal derived factor-1 (SDF-1)/CXCR4 signaling pathways may play a critical role in regulating homing and angiogenesis of EPCs in this process.However,the interaction between ERa and SDF-1/CXCR4 signaling pathways remains unclear.In response to E2,the expression of SDF-1 and CXCR4 in EPCs from ovariectomized BALB/C mice was obviously up-regulated,in addition,the migration and tube formation of EPCs in vitro were also significantly enhanced.However,ERα antagonist (MMP)and CXCR4 inhibitor (AMD3100)significantly decreased the migration The combined treatment of MMP and AMD3100 and tube length of EPCs,even if mediated by E2. exerted more inhibitory effects on migration and tube formation of EPCs induced by E2.In in vivo studies,ovariectomized mice were induced acute myocardial infarction (AMI),and divided into four groups (n =6):non-preconditioned EPCs (3 × 10^6)group,E2-preconditioned EPCs group,MMP +AMD3100 preconditioned EPCs group,and EPCs pretreated with E2 +MMP +AMD3100 group.E2 group displayed a greater number of homing EPCs,increased capillary density in infarcted myocardium,decreased left ventricular (LV) fibrosis.Nevertheless,these effects of E2 were almost completely blocked by the combined treatment of MMP and AMD3100.E2 can produce cardiovascular protective effects in AMI setting by enhancing homing and angiogenic capacity of EPCs through ERα and CXCR4 signaling pathways, which means that ERα and CXCR4 pathways are effective targets for the development of treatment strategies for AMI. | Zhize Yuan Lei Kang Zhe Wang Anqing Chen Qiang Zhao Haiqing Li | 2018 | Acta Biochimica et Biophysica Sinica2018,50,12: | 6 |
| 2 | Dark matter direct search sensitivity of the PandaX-4T experiment显示文摘The Panda X-4T experiment, a 4-ton scale dark matter direct detection experiment, is being planned at the China Jinping Underground Laboratory. In this paper we present a simulation study of the expected background in this experiment. In a 2.8-ton fiducial mass and the signal region between 1-10 keV electron equivalent energy, the total electron recoil background is found to be 4.9 × 10^(-5) kg^(-1) d^(-1) keV^(-1). The nuclear recoil background in the same region is 2.8 × 10^(-7) kg^(-1) d^(-1) keV^(-1). With an exposure of 5.6 ton-years, the sensitivity of Panda X-4 T could reach a minimum spin-independent dark matter-nucleon cross section of 6 × 10^(-48) cm^2 at a dark matter mass of 40 Ge V/c^2. | HongGuang Zhang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui BinBin Dong DeQing Fang ChangBo Fu Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo ZhiFan Guo Ke Han ChangDa He ShengMing He Di Huang XingTao Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju ShaoLi Li Yao Li Heng Lin HuaXuan Liu JiangLai Liu YuGang Ma YaJun Mao KaiXiang Ni JinHua Ning XiangXiang Ren Fang Shi AnDi Tan AnQing Wang Cheng Wang HongWei Wang Meng Wang QiuHong Wang SiGuang Wang XiuLi Wang XuMing Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu JuMin Yuan JianFeng Yue Dan Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou | 2019 | Science China(Physics,Mechanics & Astronomy)2019,62,3: | 6 |
| 3 | Evaluation of multi-cycle performance of chemical looping dry reforming using CO_2 as an oxidant with Fe–Ni bimetallic oxides显示文摘Chemical looping dry reforming(CLDR) is an innovative technology for CO_2 utilization using the chemical looping principle.The CLDR process consists of three stages,i.e.CH4 reduction,CO_2 reforming,and air oxidation.Spinel nickel ferrite(NiFe_2O_4) was prepared and its multi-cycle performance as an oxygen carrier for CLDR was experimentally investigated.X-ray diffraction(XRD) and Laser Raman spectroscopy showed that a pure spinel crystalline phase(NiFe_2O_4) was obtained by a parallel flow co-precipitating method.NiFe_2O_4was reduced into Fe-Ni alloy and wustite(Fe_xO) during the CH_4 reduction process.Subsequent oxidation of the reduced oxygen carrier was performed with CO_2 as an oxidant to form an intermediate state:a mixture of spinel Ni_(1-x)Fe_(2+x)O_4,Fe_(2+y)O_4 and metallic Ni.And CO was generated in parallel during this stage.Approximate 185 mL of CO was generated for 1 g spinel NiFe_2O_4 in a single cycle.The intermediate oxygen carrier was fully oxidized in the air oxidation stage to form a mixture of Ni_(1+x)Fe_(2-x)O_4 and Fe_2O_3.Although the original state of oxygen carrier(NiFe_2O_4) was not fully regenerated and agglomeration was observed,a good recyclability was shown in 10 successive redox cycles. | Zhen Huang Huanqi Jiang Fang He Dezhen Chen Guoqiang Wei Kun Zhao Anqing Zheng Yipeng Feng Zengli Zhao Haibin Li | 2016 | Journal of Energy Chemistry2016,25,1: | 4 |
| 4 | THE ALL-DELAY STABILITY OF DEGENERATE DIFFERENTIAL SYSTEMS WITH DELAY显示文摘In this paper,the all-delay stability of degenerate differential systems with delay is discussed.We come up with some new criteria for evaluating the all-delay stability of degenerate differential systems with delay and degenerate neutral differential systems with delay.Also,we give an example to illustrate the main results. | Zhang Hai~(1,2) Li Xiaoyan~1 Jiang Wei~1 (1.School of Math.and Computation Science,Anhui University,Hefei 230039 2.School of Math.and Computation Science,Anqing Teachers College,Anqing 236011,Anhui) | 2008 | Annals of Differential Equations2008,24,1: | 3 |
| 5 | Different oxidation routes for lattice oxygen recovery of double-perovskite type oxides LaSrFeCoO6 as oxygen carriers for chemical looping steam methane reforming显示文摘Double-perovskite type oxide LaSrFeCoO_6(LSFCO) was used as oxygen carrier for chemical looping steam methane reforming(CL-SMR) due to its unique structure and reactivity. Two different oxidation routes,steam-oxidation and steam-air-stepwise-oxidation, were applied to investigate the recovery behaviors of the lattice oxygen in the oxygen carrier. The characterizations of the oxide were determined by X-ray diffraction(XRD), X-ray photoelectron spectroscopy(XPS), hydrogen temperature-programmed reduction(H_2-TPR) and scanning electron microscopy(SEM). The fresh sample LSFCO exhibits a monocrystalline perovskite structure with cubic symmetry and high crystallinity, except for a little impurity phase due to the antisite defect of Fe/Co disorder. The deconvolution distribution of XPS patterns indicated that Co,and Fe are predominantly in an oxidized state(Fe^(3+) and Fe^(2+)) and(Co^(2+) and Co^(3+)), while O 1s exists at three species of lattice oxygen, chemisorbed oxygen and physical adsorbed oxygen. The double perovskite structure and chemical composition recover to the original state after the steam and air oxidation, while the Co ion cannot incorporate into the double perovskite structure and thus form the CoO just via individual steam oxidation. In comparison to the two different oxidation routes, the sample obtained by steam-oxidation exhibits even higher CH_4 conversion, CO and H_2 selectivity and stronger hydrogen generation capacity. | Kun Zhao Yang Shen Zhen Huang Fang He Guoqiang Wei Anqing Zheng Haibin Li Zengli Zhao | 2017 | Journal of Energy Chemistry2017,26,3: | 3 |
| 6 | Long non-coding RNA H19 contributes to hypoxia-induced CPC injury by suppressing Sirt1 through miR-200a-3p显示文摘 | Linlin Li Qiuyun Wang Zhize Yuan Anqing Chen Zuyun Liu Haiqing Li Zhe Wang | 2018 | Acta Biochimica et Biophysica Sinica2018,50,10: | 2 |
| 7 | Chemical-Looping Reforming of Methane Using Iron Based Oxygen Carrier Modified with Low Content Nickel显示文摘Fe_(2)O_(3)/Al_(2)O_(3) and Fe_(2)O_(3)/Al_(2)O_(3) modified by low content of Ni(below 2%in weight)oxygen carriers were prepared by mechanical mixing and impregnation method.The synthesized oxygen carriers were characterized by means of X-ray diffraction(XRD),X-ray fluorescence(XRF),scanning electron microscopy(SEM),BET-surface area and temperature programmed reduction(TPR).Besides,redox cyclic reactivity and the performance of chemical looping reforming of methane of the oxygen carriers were studied in a thermal gravimetrical analysis(TGA)and fixed bed at 850℃.It was observed that the redox reactivity of the oxygen carriers is improved by Ni addition because synergic effect may occur between NiO and Fe_(2)O_(3)/Al_(2)O_(3) to form NiFe_(2)O_(4) and NiAl_(2)O_(4) spinel phases.However,the improvement was not apparent as Ni addition reached 1 wt%or more because more nickel loaded resulted in methane decomposition into H2 and carbon leading to carbon deposition.The SEM and BET analysis showed that NiFe_(2)O_(4) and NiAl_(2)O_(4) particles dispersed into the pores of the Fe_(2)O_(3)/Al_(2)O_(3) particles in the course of preparation.In addition,the resistance to sintering of the modified samples increased with the Ni addition increasing.The results of successive redox cycles showed that the Ni modified Fe_(2)O_(3)/Al_(2)O_(3) oxygen carriers have good regenerability.With integration of reactivity and carbon deposition,the content 1.04 wt%of nickel doping was an optimal amount in the three modified samples. | Guoqiang Wei Fang He Zhen Huang Kun Zhao Anqing Zheng Haibin Li | 2014 | Chinese Journal of Chemistry2014,32,12: | 2 |
| 8 | Rare Metal Materials and Engineering显示文摘 | Xiong Qingren Li Weiwei Fu Anqing | 2012 | 41 ($2): 749 (in Chinese)2012,41,2: | 1 |
| 9 | In Vivo and In Vitro investigation of titanium oxide layers coated on LTI-carbon by IBED显示文摘 | Xianghui Wang Feng Zhang Changrong Li Liujiang Yu Zhihong Zheng Xianghuai Liu Lizhi Chen Huimin Wang Anqing Chen | 2001 | Journal of Materials Science2001,,8: | 1 |
| 10 | Nano-hydroxyapatite(n-HA)involved in the regeneration of rat nerve injury triggered by overloading stretch显示文摘Damage of axon and glial scars formation both inhibit nerve regenerative growth during nerve injury.In addition,mechanical stretch at high displacement rates of 10%tensile strain can cause marked nerve injury,it is important for finding a proper nano biomaterial to repair nerve injury.Nano-hydroxyapatite(n-HA)has excellent biocompatibility and high bioactivity,which is a good candidate for biomedical engineering applications.But the certain mechanism of n-HA on the injured nerve is seldom reported.In this study,we determined the role of n-HA on the mechanical stretch-induced nerve injury at adult rat spine.Mechanical stretch under strain 10%at displacement rates of 60 mm/min can cause marked broken vessels and edema in spinal cord and dorsal root ganglion tissue in haematoxylin-eosin(HE)staining.However,n-HA application can reverse hemorrhage and edema triggered by high rates of 60 mm/min stretch.Moreover,n-HA can promote positive staining of Netrin-1 increase significantly in spinal cord and dorsal root ganglion tested by immunohistochemistry(IHC)staining.In general,our study indicated that n-HA can repair mechanical stretch-induced nerve injury,it may provide a new approach to block injury and accelerate nerve regeneration in future. | Meili Liu Chongquan Huang Zhijun Zhao Anqing Wang Ping Li Yubo Fan Gang Zhou | 2019 | Medicine in Novel Technology and Devices2019,,4: | 1 |
| 11 | Effect of torrefaction on structure and fast pyrolysis behavior of corncobs显示文摘 | Anqing Zheng Zengli Zhao Sheng Chang Zhen Huang Xiaobo Wang Fang He Haibin Li | 2013 | Bioresource Technology2013,,: | 1 |
| 12 | Matrix micrestructure deteriorations resulting from diamond incorporation in electroplated metal-diamond composites显示文摘 | Li Yundong Zhan Anqing Wang Baoan | 2008 | Surface & coatings technology2008,202,: | 1 |
| 13 | 显示文摘 | Li Yundong Zhao Anqing Lu Huiyang | 2008 | Sur- face and Coatings Technolog2008,20,: | 1 |
| 14 | Chromatographia显示文摘 | Quan Lan Li Shufen Tian Songjiang Xu Hong Lin Anqing Gu Long | 2004 | 59 : 892004,59,: | 1 |
| 15 | Antioxidant activity of polysaccharide extracted from Pleurotus eryngii显示文摘 | ZHANG Anqing LI Xueqing XING Chen et ai | 2014 | Biological Macromolecules2014,65,: | 1 |
| 16 | Zircon classification from cathodoluminescence images using deep learning显示文摘Zircon is a widely-used heavy mineral in geochronological and geochemical research because it can extract important information to understand the history and genesis of rocks. Zircon has various types,and an accurate examination of zircon type is a prerequisite procedure before further analysis.Cathodoluminescence(CL) imaging is one of the most reliable ways to classify zircons. However, current CL image examination is conducted by manual work, which is time-consuming, bias-prone, and requires expertise. An automated and bias-free method for zircon classification is absent but necessary. To this end, deep convolutional neural networks(DCNNs) and transfer learning are applied in this study to classify the common types of zircons, i.e., igneous, metamorphic, and hydrothermal zircons. An atlas with over 4000 CL images of these three types of zircons is created, and three DCNNs are trained using these images. The results of this study indicate that the DCNNs can distinguish hydrothermal zircons from other zircons, as indicated by the highest accuracy of 100%. Although similar textures in igneous and metamorphic zircons pose great challenges for zircon classification, the DCNNs successfully classify 95% igneous and 92% metamorphic zircons. This study demonstrates the high accuracy of DCNNs in zircon classification and presents the great potentiality of deep learning techniques in numerous geoscientific disciplines. | Dongyu Zheng Sixuan Wu Chao Ma Lu Xiang Li Hou Anqing Chen Mingcai Hou | 2022 | Geoscience Frontiers2022,13,6: | 0 |
| 17 | An improved evaluation of the neutron background in the PandaX-Ⅱ experiment显示文摘In dark matter direct detection experiments,neutron is a serious source of background,which can mimic the dark matter-nucleus scattering signals.In this paper,we present an improved evaluation of the neutron background in the PandaX-II dark matter experiment by a novel approach.Instead of fully relying on the Monte Carlo simulation,the overall neutron background is determined from the neutron-induced high energy signals in the data.In addition,the probability of producing a dark-matter-like background per neutron is evaluated with a complete Monte Carlo generator,where the correlated emission of neutron(s)andγ(s)in the(α,n)reactions and spontaneous fissions is taken into consideration.With this method,the neutron backgrounds in the Run 9(26-ton-day)and Run 10(28-ton-day)data sets of PandaX-II are estimated to be(0.66±0.24)and(0.47±0.25)events,respectively. | QiuHong Wang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui YingJie Fan DeQing Fang ChangBo Fu LiSheng Geng Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo Ke Han ChangDa He Di Huang Yan Huang YanLin Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju YiHui Lai Kun Liang HuaXuan Liu JiangLai Liu WenBo Ma YuGang Ma YaJun Mao Yue Meng Parinya Namwongsa KaiXiang Ni JinHua Ning XuYang Ning XiangXiang Ren ChangSong Shang Lin Si AnDi Tan AnQing Wang HongWei Wang Meng Wang SiGuang Wang XiuLi Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu Jumin Yuan Dan Zhang HongGuang Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou | 2020 | Science China(Physics,Mechanics & Astronomy)2020,63,3: | 0 |
| 18 | Photoacoustic and magnetic resonance imaging-based gene and photothermal therapy using mesoporous nanoagents显示文摘The integration of photothermal therapy(PTT)with gene therapy(GT)in a single nanoscale platform demonstrates great potential in cancer therapy.Porous iron oxide nanoagents(PIONs)are widely used as magnetic nanoagents in the drug delivery field and also serve as a photothermal nanoagent for photothermal therapy.However,the therapeutic efficacy of PIONs-mediated GT has not been studied.The long noncoding RNA(lncRNA)CRYBG3(LNC CRYBG3),a lncRNA induced by heavy ion irradiation in lung cancer cells,has been reported to directly bind to globular actin(G-actin)and cause degradation of cytoskeleton and blocking of cytokinesis,thus indicating its potential for use in GT by simulating the effect of heavy ion irradiation and functioning as an antitumor drug.In the present study,we investigated the possibility of combining PIONs-mediated PTT and LNC CRYBG3-mediated GT to destroy non-small cell lung cancer(NSCLC)cells both in vitro and in vivo.The combination therapy showed a high cancer cell killing efficacy,and the cure rate was better than that achieved using PTT or GT alone.Moreover,as a type of magnetic nanoagent,PIONs can be used for magnetic resonance imaging(MRI)and photoacoustic imaging(PAI)both in vitro and in vivo.These findings indicate that the new combination therapy has high potential for cancer treatment. | Hao Huang Guotao Yuan Ying Xu Yuan Gao Qiulian Mao Yin Zhang Lu Bai Weijie Li Anqing Wu Wentao Hu Yue Pan Guangming Zhou | 2022 | Bioactive Materials2022,7,3: | 0 |
| 19 | Constraining self-interacting dark matter with the full dataset of PandaX-II显示文摘Self-interacting dark matter(SIDM)is a leading candidate proposed to solve discrepancies between predictions of the prevailing cold dark matter theory and observations of galaxies.Many SIDM models predict the existence of a light force carrier that mediates strong dark matter self-interactions.If the mediator couples to the standard model particles,it could produce characteristic signals in dark matter direct detection experiments.We report searches for signals of SIDM models with a light mediator using the full dataset of the PandaX-II experiment,basing on a total exposure of 132 tonne-days.No significant excess over background is found,and our likelihood analysis leads to a strong upper limit on the dark matter-nucleon coupling strength.We further combine the PandaX-II constraints and those from observations of the light element abundances in the early universe,and show that direct detection and cosmological probes can provide complementary constraints on dark matter models with a light mediator. | Jijun Yang Abdusalam Abdukerim Wei Chen Xun Chen Yunhua Chen Chen Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Shengming He Di Huang Yan Huang Ran Huo Yanlin Huang Zhou Huang Xiangdong Ji Yonglin Ju Shuaijie Li Qing Lin Huaxuan Liu Jianglai Liu Xiaoying Lu Wenbo Ma Yugang Ma Yajun Mao Yue Meng Nasir Shaheed Kaixiang Ni Jinhua Ning Xuyang Ning Xiangxiang Ren Changsong Shang Guofang Shen Lin Si Andi Tan Anqing Wang Hongwei Wang Meng Wang QiuHong Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Mengmeng Wu Shiyong Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Yong Yang Chunxu Yu Hai-Bo Yu Jumin Yuan Ying Yuan Xinning Zeng Dan Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou | 2021 | Science China(Physics,Mechanics & Astronomy)2021,64,11: | 0 |
| 20 | Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release. | Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou | 2023 | Research2023,,2: | 0 |