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| 1 | Aurora-A modulates MMP-2 expression via AKT/NF-κB pathway in esophageal squamous cell carcinoma cells显示文摘食道的有鳞的房间癌(ESCC ) 是最普通的恶意之一。识别预言肿瘤前进和治疗学的分子的目标的新 markersfor 是必要的。它被报导了 Aurora-Aand 矩阵 metalloproteinases 的那 overexpressions (MMP-2 ) 2 可以支持肿瘤的恶意的发展。然而,关系 betweenAurora -- 在肿瘤病人的 A 和 MMP-2 表示没被调查。另外, Aurora-Aregulates MMP-2 表示不充分仍然是的内在的机制阐明了。在这研究,我们表明了那曙光 A, MMP-2 与配对的正常邻近的纸巾相比是 overexpressedin ESCC 纸巾(P ? 0.0001 ) 。曙光 A 的 Overexpression 与 ESCC 的淋巴节点转移被联系(P ?=? 0.01 ) 。显著地,曙光 A 蛋白质表示断然在 ESCC 纸巾与 MMP-2 蛋白质表示被相关(r ?=? 0.66, P ? 0.0001 ) 象在 ESCC 一样,房间排队。曙光 A 表示的水平断然也与 ESCC 房间的 invasioncapability 被相关。而且,曙光 A overexpression 显著地由 upregulationof MMP-2 表示增加了 ESCC 房间侵略。另外,曙光 A overexpression 支持了原子 factor-kappaB (NF-B ) 激活,和 Aurora-A-mediatedMMP-2 upregulation 被 NF-B 废除禁止者。进一步的分析证明 NF-B 的激活是严重地在房间 overexpressing 曙光 A 的 attenuatedby AKT 禁止者。一起拿,这些数据通过激活在 ESCC 房间表明小径的 AKT/NF-B 显示那曙光 A overexpression upregulatesMMP-2 表情。这些调查结果揭示那曙光 A 可以是的 beused 为 ESCC 的恶意的行为的判断的重要指示物,并且可以是为 cancertherapy 的一个吸引人的目标。 | Xiaoxia Wang Xiaozhong Li Chaohui Li Chun He Benhong Ren Oing Deng Wei Gao Binquan Wang | 2016 | Acta Biochimica et Biophysica Sinica2016,48,6: | 6 |
| 2 | In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells显示文摘 | Zhenpeng Qiu Benhong Zhou Long Jin Honglian Yu Lijuan Liu Youyi Liu Chengchen Qin Shuixiang Xie Fan Zhu | 2013 | Food and Chemical Toxicology2013,,: | 3 |
| 3 | Sugar and acid concentrations in 98 grape eultivars analyzed by principal component analysis 显示文摘 | Liu Huaifeng Wu Benhong Fan Peige | 2006 | Journal of the Science of Food and Agriculture2006,86,10: | 1 |
| 4 | Simultaneous qualitative assessment and quantitative analysis of flavonoids in various tissues of lotus ( Nelumbo nucifera ) using high performance liquid chromatography coupled with triple quad mass spectrometry显示文摘 | Sha Chen Linchuan Fang Huifen Xi Le Guan Jinbao Fang Yanling Liu Benhong Wu Shaohua Li | 2012 | Analytica Chimica Acta2012,,: | 1 |
| 5 | Compositional analysis and nutritional studies of Tricholoma matsutake collected from Southwest China显示文摘 | Gang L Hui W Benhong Z | 2010 | J Med Plant Res2010,4,12: | 1 |
| 6 | Volatiles of grape berries evaluated at the germplasm level by headspace-SPME with GC–MS显示文摘 | Chunxiang Yang Yiju Wang Zhenchang Liang Peige Fan Benhong Wu Liu Yang Younian Wang Shaohua Li | 2008 | Food Chemistry2008,,3: | 1 |
| 7 | Compositional analysis and nutritional studies of Tricholoma matsutake collected from Southwest China显示文摘 | Gang L Hui W Benhong Z | 2010 | J Med Plant Res2010,4,12: | 1 |
| 8 | Anthoeyanin com- position and content in grape berry skin in Vitis germplasm显示文摘 | LIANG Zlaenchang WU Benhong FAN Peige | 2008 | Food Chemistry2008,111,4: | 1 |
| 9 | Preparation, Tg improvement, and thermal stability enhancement mechanism of soluble polyt methyl methacrylate) nanocomposites by incorporating octavinyl polyhedral oligomeric silsesquioxanes显示文摘 | XU Hongyao Yang Benhong Wang Iiaf'eng | 2007 | Journal of Polymer Science Part A: Polymer Chemistry2007,45,22: | 1 |
| 10 | Volatile compounds evolution of three table grapes with different flavour during and after maturation显示文摘 | Chunxiang Yang Yiju Wang Benhong Wu Jinbao Fang Shaohua Li | 2010 | Food Chemistry2010,,4: | 1 |
| 11 | Preparation, thermal properties and Ts increase mechanism of Poly(acetoxystyrene-co-octavinyl-polyhedral oligomeric silsesquioxane) hybrid nanocomposites 显示文摘 | Xu Hongyao Yang Benhong | 2005 | Macromolecules2005,38,10: | 1 |
| 12 | Volatile compounds evolution of three table grapes with different flavour during and after maturation 显示文摘 | Chunxiang Yang Yiju Wang Benhong Wua | 2011 | Food Chemistry2011,4,128: | 1 |
| 13 | Sugar and acid concentrations in 98 grape cultivars analyzed by principal component analysis显示文摘 | LIU Huaifeng WU Benhong FAN Peige | 2006 | Journal of the Science of Food and Agriculture2006,86,10: | 1 |
| 14 | Compositional analysis and nutritional studies of Tricholoma matsutake collected from Southwest China 显示文摘 | Gang L Hui W Benhong Z | 2010 | J Med Plant Res2010,4,12: | 1 |
| 15 | Preparation and thermal property of hybrid nanocomposites by free radical copolymerization of styrene with octavinyl polyhedral oligomeric silsesquioxane显示文摘 | Benhong Yang Hongyao Xu | | 0,,: | 1 |
| 16 | Correlation between plasma Renalase level and coro-nary artery disease 显示文摘 | He Benhong Hao Jianjun Sheng Weiwei | 2014 | Pak J Med Sci2014,30,5: | 1 |
| 17 | Camptotheca acuminata Decne Residue after Camptothecin Extract as a Substrate to Produce Mushroom Spawn显示文摘Currently in China,no technically and economically viable methods exist to handle large quantities of Camptotheca acuminata Decne residue(CA residue) after camptothecin extract while there is a great demand for low cost alternatives to replace the cottonseed hull-based materials used in commercial mushroom culture.Hence,it is of importance for camptothecin extract factories and mushroom producers to explore the utilization of CA residue in mushroom industry.We conducted a research to study how partially or completely substituting traditional mushroom substrate by CA residue would influence the mycelial growth in mushroom spawn production.5 mushroom strains from 4 species were used in the test,i.e.,oyster mushroom(Pleurotus ostreatu) strains,Zayou No.1 and Xide 33,needle mushroom(Flammulina velutipes) strain Chuanjin No.3,hairy wood ear(Auricularia polytricha) strain Huang Er No.10,and shiitake(Lentinula edodes) strain Wuxiang.The nutrient element composition and heavy metal contents of CA residue were determined to ensure its safety and to determine its appropriate component in the substrate formulation for mushroom spawn production.The four substrate formulations(one control-CK,and three treatments,named,T1,T2,T3,) contained 0%,40%,79%,and 100% CA residue,respectively,to allow comparison of the fungal mycelial growth.The control(CK) was the popularly used formulation in Chinese commercial mushroom production,comprising of 73% cottonseed hulls,10% sawdust,15% wheat bran,1% lime,1% white sugar(percentage by weight).All mushroom spawns of the five strains in the four treatments were incubated under the same conditions.The results showed that mycelia of the five mushroom strains grew significantly faster on the substrates containing CA residue than on the substrate with no CA residue(CK).There were no significant differences in the mycelial growth rate among treatments containing CA residue for the two oyster mushrooms and the needle mushroom,but mycelial growth rate in treatments T2 and T3 was significantly higher than in treatment T1 for hairy wood ear and shiitake.The results suggest that CA residue can be used to culture oyster mushroom,needle mushroom,hairy wood ear,and shiitake spawn,and the medium containing CA residue can stimulate their mycelial growth.The commercial production of mushroom spawn using CA residue not only brings better economical benefits including lower cost to mushroom producers,but also reduces environmental pollution by providing a means to reduce dumping and piling of CA residue. | QIU Dunlian LIU Benhong TANG Ya YANG Zhirong | 2012 | Journal of Mountain Science2012,9,6: | 1 |
| 18 | Sugar and acid concentrations in 98 grape cultivars analyzed by principal component analysis显示文摘 | LIU Huaifeng WU Benhong FAN Peige | 2006 | Journal of the Science of Food and Agriculture2006,86,10: | 1 |
| 19 | Compositional analysis and nutri tional studies of Tricholoma matsutake collected from Southwest China显示文摘 | Gang L Hui W Benhong Z | 2010 | J Med Plant Res2010,4,12: | 1 |
| 20 | Analysis of flavonoids from lotus (Nelumbo nucifera) leaves using high performance liquid chromatography/photodiode array detector tandem electrospray ionization mass spectrometry and an extraction method optimized by orthogonal design显示文摘 | SHA Chen WU Benhong FANG Jinbao | 2012 | Journal of Chromatography A2012,12,27: | 1 |