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| 1 | Spatiotemporal variations of internal P-loading and the related mechanisms in the large shallow Lake Chaohu显示文摘Spatiotemporal variations of P species and adsorption behavior in water column, interstitial water, and sediments were investigated in the large shallow eutrophic Lake Chaohu. Orthophosphate (Ortho-P) and total phosphorus (TP) concentrations were significantly higher in the western part than in the eastern part of the lake, due to different nutrient inputs from the surrounding rivers.Moreover, particulate phosphorus (PP) concentration was in a similar spatial pattern to Ortho-P and TP concentrations, and also showed significantly positive correlation with the biomass of Microcystis,indicating more uptake and store of phosphorus by Microcystis than by other algae. Increase of pH and intensive utilization of P by phytoplankton were the main factors promoting P (especially Fe-P)release from the sediment to interstitial water during the cyanobacterial blooms in Lake Chaohu. Spatial dynamics in TP concentration, P species and adsorption behavior of the sediment, coupled with the statistical analyses, suggested that the spatial heterogeneity of P contents in the sediment was influenced by various factors, e.g. human activities, soil geochemistry and mineral composition. In spite of similar TP contents in the sediments, increase in proportion of Fe-P concentration in the sediment may result in a high risk of P release. | ZHANG Min XIE Ping XU Jun LIU Bingqin YANG Hong | 2006 | Science China Earth Sciences2006，49，z1： | 6 |
| 2 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 3 | Effects of extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) on excisional wound healing in a rat's model显示文摘OBJEVTIVE: To investigate the effects of extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) on the excisional wound healing in a rat's model.METHODS: Rats were performed a surgical lesion with a 2.0 cm resected tissue in the dorsal fascia.Following, animals were randomly divided into model group, YNB group and APE group those were respectively treated with saline, 1 mg/mL of Yunnan Baiyao and 1 mg/mL of Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) extracts. Wound contractions in days 0, 3, 7, 14 and 21 were calculated by an image analyzer. Histological analysis was analyzed using hematoxilin and eosin.Levels of tumor necrosis factor-2(IL-2), IL-4, IL-10, transformαin(TNF-g growα), interleukinth factor-1(TGF-nd basic fibroblast growth factor(bFββ1) a-GF) were determined by real-time quantitative PCR.RESULTS: Compared with that of YNB group and APE gtoup, the skin of rats showed poor re-modeling and re-epithelization characterized by a significant decrease of neovascularization, epithelialization and fibroblast in the model group. In the APE group, levels of TNF-α-and IL-2 were significantly down-regulated and IL4 and IL-10 significantly upregulated in contrasted with that of model group.In addition, levels of TGF-roup were significantly iβ1 and bFGF in the APE gnduced compared with that of model group.CONCLUSION: The results suggest that the extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) promote wound healing in the rats, which is associated with enhancing antiinflammatory ability and inducing fibroblast formation. | Xia Xichao Ma Yuhong Wang Fuan Zheng Xinhua Liu Yang Zhang Junfeng Cui Juan Shi Bingqin Li Hongwen Liu Rongzhi Zhang Yaping Cheng Zhaofei Han Xiaolong | 2019 | Journal of Traditional Chinese Medicine2019，39，1： | 4 |
| 4 | Building Healthy Cities: the Experience and Challenges Faced by China 显示文摘 | Li Bingqin | 2011 | Urban age2011，，11： | 1 |
| 5 | Response of daily stem radial growth of Platycladus onentahs toenvironmental factors in a semi-arid area of North China显示文摘 | JIANG Yuan WANG Bingqin DONG Manyu | 2015 | Trees2015，29，1： | 1 |
| 6 | Floating Population or Urban Citizens? Status, Social Provision and Circumstances of Rural-Urban Migrants in China 显示文摘 | Li Bingqin | 2006 | Social Policy and Administration2006，40，2： | 1 |
| 7 | Response of daily stem radial growth of Platycladus orientalis to environ- mental factors in a semi-add area of North China 显示文摘 | JIANG Yuan WANG Bingqin Dong Manyu | 2015 | Trees2015，29，： | 1 |
| 8 | Vascular endothelial growth factor and recurrent spontaneous abortion: A meta-analysis显示文摘 | Bingzhen Zhang Bingqin Dai Xingliang Zhang Zhiping Wang | 2012 | Gene2012，，： | 1 |
| 9 | Recent development of conjugated oligomers for high-efficiency bulk-heterojunction solar cells显示文摘 | Weihua Tang Jiefeng Hai Yun Dai Zongjun Huang Bingqin Lu Fei Yuan Jian Tang Fujun Zhang | 2010 | Solar Energy Materials and Solar Cells2010，，12： | 1 |
| 10 | Crystal Structure And Magnetic Property of the Complex of Hydrogen-bonded Two-dimensional Layer Copper(Ⅱ)Acrylate with Trimethyl Phosphate显示文摘 | WANG Yaoyu SHI Qian YANG Bingqin GAO Yici SHI Qizhen | 2000 | Chemical Research in Chinese Universities2000，16，2： | 0 |
| 11 | Coordinated Development of Tourism Economy and Ecological Environment Coupling in Mountainous Provinces:A Case Study of Guizhou显示文摘The degree of coupling coordination can reflect the intensity of interaction between multiple-indicator system,and can characterize the harmonious and consistent degree of benign correlation between them.It is an effective measurement method for analyzing the level of coordinated development of tourism economy and ecological environment coupling.Guizhou,a mountainous province,is taken as the research object in this paper.Using entropy method and coupling coordination model,the coordinated development level of tourism economy and ecological environment coupling during 2011-2020 is measured and analyzed,and the coordinated development strategies for the tourism economy and ecological environment coupling in Guizhou,a mountainous province,are proposed. | WU Bingqin ZHANG Chengru | 2023 | Journal of Landscape Research2023，15，4： | 0 |
| 12 | A novel method for the formylation of Grignard reagent显示文摘A facile and efficient method for the formylation of Grignard reagent was reported, and a new approach for the preparation of aldehydes from Grignard reagent and benzimidazolium salts was provided. | SHI Zhen WANG Luyao GU Huan LI Jianli BAI Yinjuan YANG Bingqin | 2005 | Science China Chemistry2005，48，z1： | 0 |
| 13 | Synthesis of novel macrocyclic host tetraazaparacyclo-phane derivatives显示文摘Seven macrocyclic host tetraazaparacyclophanes with different hydrophobic cavity sizes were synthesized from dibromoalkanes and 4,4'-methylendianilin. Three of the tetraazacyclophanes were modified on the four nitrogen atoms by using ferrocenoyl chloride, so a new kind of enzyme model was obtained by introducing the side arms of ferrocenoyl group. And four of the tetraazacyclophanes with straight chains were also synthesized through the reaction of 1,8,22,29-tetraaza[8.1.8.1] paracyclophane with bromoalkane and alkanecarbonyl bromide. Ten of them have not ever been reported in literature. The structures were confirmed by 1H NMR, 13C NMR, IR, MS and elemental analysis. | BAI Yinjuan SU Yuchan LI Jianli YANG Bingqin SHI Zhen | 2005 | Science China Chemistry2005，48，z1： | 0 |
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