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| 1 | Establishment of Withania somnifera Hairy Root Cultures for the Production of Withanolide A显示文摘Withania sominifera (Indian ginseng) was transformed by Agrobacterium rhizogenes. Explants from seedling roots, stems, hypocotyls, cotyledonary nodal segments, cotyledons and young leaves were inoculated with A. rhizogenes strain R1601. Hairy (transformed) roots were induced from cotyledons and leaf explants. The transgenic status of hairy roots was confirmed by polymerase chain reaction using nptII and rolB specific primers and, subsequently, by Southern analysis for the presence of nptII and rolB genes in the genomes of transformed roots. Four clones of hairy roots were established; these differed in their morphology. The doubling time of faster growing cultures was 8-14 d with a fivefold increase in biomass after 28 d compared with cultured, non-transformed seedling roots. MS-based liquid medium was superior for the growth of transformed roots compared with other culture media evaluated (SH, LS and N6), with MS-based medium supplemented with 40 g/L sucrose being optimal for biomass production. Cultured hairy roots synthesized withanolide A, a steroidal lactone of medicinal and therapeutic value. The concentration of withanolide A in transformed roots (157.4 μg/g dry weight) was 2.7-fold more than in non-transformed cultured roots (57.9 μg/g dry weight). | Hosakatte N. Murthy Camelia Dijkstra Paul Anthony Daniel A. White Mike R. Davey J. Brian Power Eun J. Hahn Kee Y. Paek | 2008 | Journal of Integrative Plant Biology2008，50，8： | 3 |
| 2 | Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis显示文摘 | Kurt Degenhardt Robin Mathew Brian Beaudoin Kevin Bray Diana Anderson Guanghua Chen Chandreyee Mukherjee Yufang Shi Céline Gélinas Yongjun Fan Deirdre A. Nelson Shengkan Jin Eileen White | 2006 | Cancer Cell2006，，1： | 2 |
| 3 | Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy显示文摘 | Ting-Ting Tan Kurt Degenhardt Deirdre A. Nelson Brian Beaudoin Wilberto Nieves-Neira Philippe Bouillet Andreas Villunger Jerry M. Adams Eileen White | 2005 | Cancer Cell2005，，3： | 2 |
| 4 | T-DNA analysis of plants regenerated from hairy root tumors显示文摘 | Brian H. Taylor Richard M. Amasino Frank F. White Eugene W. Nester Milton P. Gordon | 1985 | MGG Molecular & General Genetics1985，，3： | 2 |
| 5 | Quantification of aortic stiffness using MR Elastography and its comparison to MRI‐based pulse wave velocity显示文摘 | Anirudh R. Damughatla Brian Raterman Travis Sharkey‐Toppen Ning Jin Orlando P. Simonetti Richard D. White Arunark Kolipaka | 2015 | J. Magn. Reson. Imaging2015，，： | 1 |
| 6 | Aeees- sing Web Database Using OGSA-DAI in BDWorld 显示文摘 | Shirley Crompton Brian Matthews Alex Gray Andrew Jones and Richard White | 2007 | Knowledge and data management in GRIDS2007，，： | 1 |
| 7 | Guyed structures for transmission lines 显示文摘 | Brian White H | 1993 | Engineering Structures1993，，7： | 1 |
| 8 | Separation and capture of COs from large stationary sources and sequestration in geological formations - coal beds and deep saline aquifers 显示文摘 | White Curt M Strazisar Brian R Granit Evan J | 2003 | Air &Waste Man- agement Association2003，53，： | 1 |
| 9 | Combined Antioxidant Therapy Reduces Pain and Improves Quality of Life in Chronic Pancreatitis显示文摘 | Gareth R. Kirk Jonathan S. White Lloyd McKie Mike Stevenson Ian Young W.D. Barry Clements Brian J. Rowlands | 2006 | Journal of Gastrointestinal Surgery2006，，4： | 1 |
| 10 | Significance of Histological Response to Preoperative Chemoradiotherapy for Pancreatic Cancer显示文摘 | Rebekah R. White MD H. Bill Xie MD PhD Marcia R. Gottfried MD Brian G. Czito MD Herbert I. Hurwitz MD Michael A. Morse MD Gerald C. Blobe MD PhD Erik K. Paulson MD John Baillie MB ChB M. Stanley Branch MD Paul S. Jowell MB ChB Bryan M. Clary MD Theodo | 2005 | Annals of Surgical Oncology2005，，3： | 1 |
| 11 | Managing Inventory in Global Supply Chains Facing Port-of-Entry Disruption Risks显示文摘 | Lewis Brian M Erera Alan L Nowak Maciek A White Chelsea C | 2013 | Transportation Science2013，，2： | 1 |
| 12 | Separation and capture of CO2 from large stationary sources and sequestration in geological formations-coalbeds and deep saline aquifers显示文摘 | WHITE CURT M STRAZISAR BRIAN R GRANIT EVAN J | 2003 | Air & Waste Management Association2003，53，10473289： | 1 |
| 13 | The role of miR -206 in the epidermal growth factor (EGF) induced repression of estrogen receptor - (ER) signaling and a luminal rhenotype in MCF - 7 breast cancer cells 显示文摘 | Brian D Adams Henry Furneaux Bruce A White | 2009 | Mol Endocrinol2009，23，8： | 1 |
| 14 | Transcription of Agrobacterium rhizogenes A4 T-DNA显示文摘 | Brian H. Taylor Frank F. White Eugene W. Nester Milton P. Gordon | 1985 | MGG Molecular & General Genetics1985，，3： | 1 |
| 15 | Nucleotide sequence ofCab-215, a Type II gene encoding a photosystem II chlorophylla/b-binding protein inPisum显示文摘 | Denis Falconet Michael J. White Brian W. Fristensky Michael S. Dobres William F. Thompson | 1991 | Plant Molecular Biology1991，，1： | 1 |
| 16 | Sevoflurane for Outpatient Anesthesia: A Comparison with Propofol显示文摘 | Brian Fredman Michael H. Nathanson Ian Smith Junke Wang Kevin Klein Paul White | 1995 | Anesthesia & Analgesia1995，，4： | 1 |
| 17 | Autophagy Suppresses Tumorigenesis through Elimination of p62显示文摘 | Robin Mathew Cristina M. Karp Brian Beaudoin Nhan Vuong Guanghua Chen Hsin-Yi Chen Kevin Bray Anupama Reddy Gyan Bhanot Celine Gelinas Robert S. DiPaola Vassiliki Karantza-Wadsworth Eileen White | 2009 | Cell2009，，6： | 1 |
| 18 | Separation and capture of CO2 from large stationary sources and sequestration in geological formations-coal beds and deep saline aquifers 显示文摘 | Curt M White Brian R Strazisar Evan J Granite | 2003 | Air & Waste Management Association2003，53，10473289： | 1 |
| 19 | Synthesis and structural characterization of the adducts of silver(I) perchlorate and nitrate with triphenylphosphine and bis(pyrazolyl)methane ligands of 1:1:1 stoichiometry显示文摘 | Adele Cerquetella Effendy Claudio Pettinari Riccardo Pettinari Brian W. Skelton Allan H. White | 2006 | Inorganica Chimica Acta2006，，7： | 1 |
| 20 | Acute Coronary Care in the Elderly, Part I. Non–ST-Segment–Elevation Acute Coronary Syndromes: A Scientific Statement for Healthcare Professionals From the American Heart Association Council on Clinical Cardiology显示文摘 | Karen P. Alexander L Kristin Newby Christopher P. Cannon Paul W. Armstrong W Brian Gibler Michael W. Rich Frans Van de Werf Harvey D. White W Douglas Weaver Mary D. Naylor Joel M. Gore Harlan M. Krumholz E Magnus Ohman | 2007 | Circulation2007，，19： | 1 |
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