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| 1 | Analysis of Pathological data of renal biopsy at one single center in China from 1987 to 2012显示文摘 | Zhang Xueguang Liu Shuwen Tang Li Wu Jie Chen Pu Yin Zhong Li Minxia Xie Yuansheng Cai Guangyan Wei Ribao Qiu Qiang Wang Yuanda Shi Suozhu Chen Xiangmei | 2014 | Chinese Medical Journal2014，，9： | 30 |
| 2 | nterferon alpha (IFNα)-induced TRIM22 interrupts HCV 'eplication by ubiquitinating NS5A显示文摘 | Chen Yang Xinhao Zhao Dakang Sun Leilei Yang Chang Chong Yu Pan Xiumei Chi Yanhang Gao Moli Wang Xiaodong Shi Haibo Sun Juan Lv Yuanda Gao Jin Zhong Junqi Niu Bing Sun | 2016 | Cellular & Molecular Immunology2016，13，1： | 13 |
| 3 | An acoustic-wave theory for casing bond evaluation using viscoelastic slip boundary modeling显示文摘Slip boundary condition is commonly utilized to model elastic wave propagation through layered earth media. The same approach is used here to characterize acoustic wave propagation along a cased borehole with various cement bond conditions. By modeling the cement layer between casing and formation as a viscoelastic slip interface with complex coupling rigidity parameters, one can not only reduce the complexity in the classical elastic wave modeling of the problem, but also efficiently model various complicated wave phenomena that are difficult for the existing modeling. More specifically, the new theory can well describe the effect of the cement bond condition change and the location of the change(i.e., whether it is in the first interface between casing and cement, or the second interface between cement and formation) on the acoustic waves,demonstrating the good modeling capability and predicting power. Application of the theory to field data shows that the theory can correctly model the acoustic wave characteristics and interpret the cement bond condition, thus providing a useful fundament theory for casing bond evaluation using acoustic logging. | Xiaoming TANG Can JIANG YuANDa SU Xuelian CHEN | 2018 | Science China Earth Sciences2018，61，8： | 4 |
| 4 | Interference at the single-photon level based on silica photonics robust against channel disturbance显示文摘Quantum key distribution(QKD) provides a solution for communication of unconditional security. However,the quantum channel disturbance in the field severely increases the quantum bit-error rate, degrading the performance of a QKD system. Here we present a setup comprising silica planar light wave circuits(PLCs), which is robust against the channel polarization disturbance. Our PLCs are based on the asymmetric Mach–Zehnder interferometer(AMZI), integrated with a tunable power splitter and thermo-optic phase modulators. The polarization characteristics of the AMZI PLC are investigated by a novel pulse self-interfering method to determine the operation temperature of implementing polarization insensitivity. Over a 20 km fiber channel with 30 Hz polarization scrambling, our time-bin phase-encoding QKD setup is characterized with an interference fringe visibility of 98.72%. The extinction ratio for the phase states is kept between 18 and 21 d B for 6 h without active phase correction. | XIAO LI MEIZHEN REN JIASHUN ZHANG LIANGLIANG WANG WEI CHEN YUE WANG XIAOJIE YIN YUANDA WU JUNMING AN | 2021 | Photonics Research2021，9，2： | 2 |
| 5 | Concomitant chemoradiotherapy using pemetrexed and carboplatin for unresectable stage III non-small cell lung cancer (NSCLC): Preliminary results of a phase II study显示文摘 | Yaping Xu Shenglin Ma Yongling Ji Xiaojiang Sun Hao Jiang Jianxiang Chen Xianghui Du Yuanda Zheng Guoqin Qiu | 2010 | Lung Cancer2010，，3： | 1 |
| 6 | Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein(RNP)to inhibit herpes simplex virus1 infection in vitro and in vivo显示文摘Extracellular vesicles(EVs)have recently emerged as a promising delivery platform for CRISPR/Cas9 ribonucleoproteins(RNPs),owing to their ability to minimize off-target effects and immune responses.However,enhancements are required to boost the efficiency and safety of Cas9 RNP enrichment within EVs.In response,we employed the Fc/Spa interaction system,in which the human Fc domain was fused to the intracellular domain of PTGFRN-Δ687 and anchored to the EV membrane.Simultaneously,the B domain of the Spa protein was fused to the C domain of cargos such as Cre or spCas9.Due to the robust interaction between Fc and Spa,this method enriched nearly twice the amount of cargo within the EVs.EVs loaded with spCas9 RNP targeting the HSV1 genome exhibited significant inhibition of viral replication in vitro and in vivo.Moreover,following neuron-targeting peptide RVG modification,the in vivo dosage in neural tissues substantially increased,contributing to the clearance of the HSV1 virus in neural tissues and exhibiting a lower off-target efficiency.These findings establish a robust platform for efficient EV-based SpCas9 delivery,offering potential therapeutic advantages for HSV1 infections and other neurological disorders. | Yuanda Wan Liren Li Ruilin Chen Jiajia Han Qiyun Lei Zhipeng Chen Xiaodong Tang Wenyu Wu Shuwen Liu Xingang Yao | 2024 | Acta Pharmaceutica Sinica B2024，14，3： | 0 |
| 7 | Venovenous extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome:A comparative cohort study in China显示文摘Background Venovenous extracorporeal membrane oxygenation(VV-ECMO)has been demonstrated to be effective in treating patients with virus-induced acute respiratory distress syndrome(ARDS).However,whether the management of ECMO is different in treating H1N1 influenza and coronavirus disease 2019(COVID-19)-associated ARDS patients remains unknown.Methods This is a retrospective cohort study.We included 12 VV-ECMO-supported COVID-19 patients admitted to The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Eighth People's Hospital,and Wuhan Union Hospital West Campus between January 23 and March 31,2020.We retrospectively included VV-ECMO-supported patients with COVID-19 and H1N1 influenza-associated ARDS.Clinical characteristics,respiratory mechanics including plateau pressure,driving pressure,mechanical power,ventilatory ratio(VR)and lung compliance,and outcomes were compared.Results Data from 25 patients with COVID-19(n=12)and H1N1(n=13)associated ARDS who had received ECMO support were analyzed.COVID-19 patients were older than H1N1 influenza patients(P=0.004).The partial pressure of arterial carbon dioxide(PaCO_(2))and VR before ECMO initiation were significantly higher in COVID-19 patients than in H1N1 influenza patients(P<0.001 and P=0.004,respectively).COVID-19 patients showed increased plateau and driving pressure compared with H1N1 subjects(P=0.013 and P=0.018,respectively).Patients with COVID-19 remained longer on ECMO support than did H1N1 influenza patients(P=0.015).COVID-19 patients who required ECMO support also had fewer intensive care unit and ventilator-free days than H1N1.Conclusions Compared with H1N1 influenza patients,COVID-19 patients were older and presented with increased PaCO_(2) and VR values before ECMO initiation.The differences between ARDS patients with COVID-19 and influenza on VV-ECMO detailed herein could be helpful for obtaining a better understanding of COVID-19 and for better clinical management. | Yonghao Xu Yin Xi Shuijiang Cai Yuheng Yu Sibei Chen Weijie Guan Weibo Liang Hongkai Wu Weiqun He Xilong Deng Yuanda Xu Rong Zhang Manshu Li Jieyi Pan Zhenting Liang Ya Wang Shaofeng Kong Xiaoqing Liu Zheng Lv Yimin Li | 2023 | Journal of Intensive Medicine2023，3，4： | 0 |
| 8 | Grain Growth Kinetics and Debye Temperature of Nanometer TiO_2 Powders Prepared by a Sol-gel Process显示文摘The development of microstructure of nanometer TiO2 powders prepared by a sol-gel process was systematically studied. Grain growth was mon itored using X-ray diffraction (XRD) and transmission electron microscopy (TEM). and the Debye temperature of anatase crystallites was determined. It was found that the grain size of the powders increased slowly with annealing temperature up to 773 K. but grew rapidly in the temperature range of 773-1273K. The activation energies (Ea) for the growth of anatase crystallites in the two temperature regions were calculated to be 16 and 90 kJ / mol, respectively. The Debye temperatures of nanocrystalline anatase powders were all lower than that of microcrystalline anatase. which implies that the bonding force between Ti and O atoms in nanocrystalline TiO2 shourd be smaller than that in microcrystalline state. However. it was noted that the Debye temperature of nanocrystalline anatase increased with the decrease of grain size. This may be attributed to the enhancement in atomic bonding force due to the existence of high surface tension in nanocrystalline | Ju LUO Xingzhao DING Benpei CHEN and Jie KONG(Institute of Solid State Physics, Academia Sinica, Hefei, 230031, China)Yuanda DONG(Dept. of Metallurgy and Materials, Shanghai University of Technology, Shanghai, 200072, China) | 1994 | Journal of Materials Science & Technology1994，10，3： | 0 |
| 9 | Experimental investigation on indoor daylight environment of building with Cadmium Telluride photovoltaic window显示文摘Photovoltaic(PV)windows have received more and more attention in recent years since their active energy-saving advantages.Considering the surface covered with solar cell modules,the indoor daylight environment of PV windows is obviously different with clear glass windows.However,despite many scholars have studied the indoor daylight environment of PV windows,there few investigations study it from the perspective of human subjective visual perception.In this paper,the indoor daylight environment and human visual comfort of building with Cadmium Telluride Photovoltaic(CdTe-PV)window were investigated.Firstly,the parameters of indoor daylight environment and subjective questionnaires in rooms with CdTe-PV window and clear glass window were analyzed respectively.On the basis of this,combined with indoor working surface illuminance and results of subjective questionnaires,the daylight illuminance threshold of human visual comfort was investigated by the method of Mean Bias Degree(MBD).Finally,an evaluation model for indoor daylight environment of buildings with CdTe-PV window was developed by Fuzzy Comprehensive Evaluation Method.The results showed that the working surface illuminance of CdTe-PV window was lower than that of clear glass room,the CCT of different windows room had a minor gap and the CdTe-PV window room was closer to the recommended range that was 3300-5000K.As for CRI,both the CdTe-PV window room and the clear glass room could meet the visual comfort requirements of office staff.Furthermore,it was found that the requirement of human visual comfort was met when indoor working surface illuminance varies between 500-2200lx in the room with CdTe-PV window.At last,according to the comprehensive evaluation model proposed in this paper,it was found that the indoor daylight environment of buildings with CdTe-PV window was excellent in the present experiment. | Yilin Hu Qingwen Xue Haobo Wang Peng Zou Jinming Yang Shikeng Chen Yuanda Cheng | 2024 | Energy and Built Environment2024，5，3： | 0 |
| 10 | A Chemical Dealloying Approach for Pt Surface-enriched Pt_(3)Co Alloy Nanoparticles as Oxygen Reduction Reaction Electrocatalysts显示文摘Pt-based alloys are the optimal electrocatalysts for oxygen reduction reaction(ORR)currently.Dealloying of Pt-based alloys has shown to be an effective approach to improving ORR activity.Electrochemical dealloying is controllable for morphology by changing electrochemical parameters but is difficult to scale up due to complex operation and energy consumption.Chemical dealloying is suitable for a large scale but it is not easy to control the morphology because highly corrosive acids(HNO_(3) or H2SO4)are commonly used.In this work,a facile chemical dealloying method for Pt_(3)Co/C has been employed to synthesize electrocatalysts for ORR using weak acids and buffer solutions of different pH,which could slow down the dissolution rate for Co atoms and increase the diffusion time for Pt atoms to improve ORR activity.It can be observed that the mass activities(MA)of the Pt_(3)Co/C alloy after dealloying with H3PO4 and NaH2PO4/Na2HPO4 buffer solution of pH=6 are close to that after electrochemical dealloying process,and are more than two times that of commercial Pt/C.In addition,Pt_(3)Co/C after dealloying with a buffer solution of pH=6 only showed a slight degradation in the half-wave potential and electrochemical surface area(ECSA)after stability test for 5000 cycles,which is more stable than commercial Pt/C.It shows that by controlling pH of the solvent,the ORR activity can be further increased.This facile approach provides a new strategy to control morphology of Pt-based electrocatalysts by chemical dealloying,which can contribute to promising application for cathodic electrocatalysts design of proton exchange membrane fuel cells(PEMFCs). | CHEN Yuanda CHEN Yongting LIO Yuxiang CHEN Shengli | 2022 | Chemical Research in Chinese Universities2022，38，4： | 0 |
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