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| 1 | Spatiotemporal Patterns of Road Network and Road Development Pri-ority in Three Parallel Rivers Region in Yunnan,China:An Evaluation Based on Modified Kernel Distance Estimate显示文摘Road network is a critical component of public infrastructure,and the supporting system of social and economic development.Based on a modified kernel density estimate(KDE)algorithm,this study evaluated the road service capacity provided by a road network composed of multi-level roads(i.e.national,provincial,county and rural roads),by taking account of the differences of effect extent and intensity for roads of different levels.Summarized at town scale,the population burden and the annual rural economic income of unit road service capacity were used as the surrogates of social and economic demands for road service.This method was applied to the road network of the Three Parallel River Region,the northwestern Yunnan Province,China to evaluate the development of road network in this region.In results,the total road length of this region in 2005 was 3.70×104km,and the length ratio between national,provincial,county and rural roads was 1∶2∶8∶47.From 1989 to 2005,the regional road service capacity increased by 13.1%,of which the contributions from the national,provincial,county and rural roads were 11.1%,19.4%,22.6%,and 67.8%,respectively,revealing the effect of′All Village Accessible′policy of road development in the mountainous regions in the last decade.The spatial patterns of population burden and economic requirement of unit road service suggested that the areas farther away from the national and provincial roads have higher road development priority(RDP).Based on the modified KDE model and the framework of RDP evaluation,this study provided a useful approach for developing an optimal plan of road development at regional scale. | YING Lingxiao SHEN Zehao CHEN Jiding FANG Rui CHEN Xueping JIANG Rui | 2014 | Chinese Geographical Science2014，24，1： | 7 |
| 2 | 3D-printed models improve surgical planning for correction of severe postburn ankle contracture with an external fixator显示文摘Gradual distraction with an external fixator is a widely used treatment for severe postburn ankle contracture(SPAC).However,application of external fixators is complex,and conventional two-dimensional(2D)imaging-based surgical planning is not particularly helpful due to a lack of spatial geometry.The purpose of this study was to evaluate the surgical planning process for this procedure with patient-specific three-dimension-printed models(3DPMs).In this study,patients coming from two centers were divided into two cohorts(3DPM group vs.control group)depending on whether a 3DPM was used for preoperative surgical planning.Operation duration,improvement in metatarsal-tibial angle(MTA),range of motion(ROM),the American Orthopedic Foot and Ankle Society(AOFAS)scores,complications,and patient-reported satisfaction were compared between two groups.The 3DPM group had significantly shorter operation duration than the control group((2.0±0.3)h vs.(3.2±0.3)h,P<0.01).MTA,ROM,and AOFAS scores between the two groups showed no significant differences pre-operation,after the removal of the external fixator,or at follow-up.Plantigrade feet were achieved and gait was substantially improved in all patients at the final follow-up.Pin-tract infections occurred in two patients(one in each group)during distraction and were treated with wound care and oral antibiotics.Patients in the 3DPM group reported higher satisfaction than those in the control group,owing to better patient-surgeon communication.Surgical planning using patient-specific 3DPMs significantly reduced operation duration and increased patient satisfaction,while providing similar improvements in ankle movement and function compared to traditional surgical planning for the correction of SPAC with external fixators. | Youbai CHEN Zehao NIU Weiqian JIANG Ran TAO Yonghong LEI Lingli GUO Kexue ZHANG Wensen XIA Baoqiang SONG Luyu HUANG Qixu ZHANG Yan HAN | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，10： | 3 |
| 3 | Accuracy assessment and error analysis for diameter at breast height measurement of trees obtained using a novel backpack LiDAR system显示文摘Background: The LiBackpack is a recently developed backpack light detection and ranging(LiDAR) system that combines the flexibility of human walking with the nearby measurement in all directions to provide a novel and efficient approach to LiDAR remote sensing, especially useful for forest structure inventory. However, the measurement accuracy and error sources have not been systematically explored for this system.Method: In this study, we used the LiBackpack D-50 system to measure the diameter at breast height(DBH) for a Pinus sylvestris tree population in the Saihanba National Forest Park of China, and estimated the accuracy of LiBackpack measurements of DBH based on comparisons with manually measured DBH values in the field. We determined the optimal vertical slice thickness of the point cloud sample for achieving the most stable and accurate LiBackpack measurements of DBH for this tree species, and explored the effects of different factors on the measurement error.Result: 1) A vertical thickness of 30 cm for the point cloud sample slice provided the highest fitting accuracy(adjusted R2= 0.89, Root Mean Squared Error(RMSE) = 20.85 mm);2) the point cloud density had a significant negative, logarithmic relationship with measurement error of DBH and it explained 35.1% of the measurement error;3) the LiBackpack measurements of DBH were generally smaller than the manually measured values, and the corresponding measurement errors increased for larger trees;and 4) by considering the effect of the point cloud density correction, a transitional model can be fitted to approximate field measured DBH using LiBackpackscanned value with satisfactory accuracy(adjusted R2= 0.920;RMSE = 14.77 mm), and decrease the predicting error by 29.2%. Our study confirmed the reliability of the novel LiBackpack system in accurate forestry inventory, set up a useful transitional model between scanning data and the traditional manual-measured data specifically for P.sylvestris, and implied the applicable substitution of this new approach for more species, with necessary parameter calibration. | Yuyang Xie Jie Zhang Xiangwu Chen Shuxin Pang Hui Zeng Zehao Shen | 2020 | Forest Ecosystems2020，7，3： | 2 |
| 4 | Laser powder bed fusion of high-strength Sc/Zr-modified Al–Mg alloy:phase selection,microstructural/mechanical heterogeneity,and tensile deformation behavior显示文摘Laser powder bed fusion(L-PBF)of Sc/Zr-modified Al-based alloys has recently become a promising method for developing a new generation of high-performance Al alloys.To clarify the modification roles of Sc/Zr elements,an Al–4.66Mg–0.48Mn–0.72Sc–0.33Zr(wt.%)alloy was processed using L-PBF.The effect of the local solidification condition of the molten pool on the precipitation behavior of primary Al_(3)(Sc,Zr)was analyzed based on time-dependent nucleation theory.It was found that primary Al_(3)(Sc,Zr)inevitably precipitated at the fusion boundary,while its precipitation could be effectively suppressed in the inner region of the molten pool.This subsequently induced the formation of a heterogeneousα-Al matrix.After direct aging,the heredity of solidification microstructure introduced heterogeneous secondary Al_(3)(Sc,Zr)precipitates withinα-Al matrix.Owing to the inverse relationship between grain boundary strengthening and precipitation strengthening,the direct-aged sample with dual heterogeneous structures exhibited reduced mechanical heterogeneity,resulting in lowered hetero-deformation-induced hardening.The low strain-hardening capability in the direct-aged sample promoted necking instability while inducing a large Lüders elongation,which effectively improved the tensile ductility. | Zihong Wang Xin Lin Nan Kang Jing Chen Hua Tan Zhe Feng Zehao Qin Haiou Yang Weidong Huang | 2021 | Journal of Materials Science & Technology2021，，36： | 2 |
| 5 | 3D-printed cell-free PCL-MECM scaffold with biomimetic micro-structure and micro-environment to enhance in situ meniscus regeneration显示文摘Despite intensive effort was made to regenerate injured meniscus by cell-free strategies through recruiting endogenous stem/progenitor cells,meniscus regeneration remains a great challenge in clinic.In this study,we found decellularized meniscal extracellular matrix(MECM)preserved native meniscal collagen and glycosaminoglycans which could be a good endogenous regeneration guider for stem cells.Moreover,MECM significantly promoted meniscal fibrochondrocytes viability and proliferation,increased the expression of type II collagen and proteoglycans in vitro.Meanwhile,we designed 3D-printed polycaprolactone(PCL)scaffolds which mimic the circumferential and radial collagen orientation in native meniscus.Taken these two advantages together,a micro-structure and micro-environment dually biomimetic cell-free scaffold was manipulated.This cell-free PCL-MECM scaffold displayed superior biocompatibility and yielded favorable biomechanical capacities closely to native meniscus.Strikingly,neo-menisci were regenerated within PCL-MECM scaffolds which were transplanted into knee joints underwent medial meniscectomy in rabbits and sheep models.Histological staining confirmed neo-menisci showed meniscus-like heterogeneous staining.Mankin scores showed PCL-MECM scaffold could protect articular cartilage well,and knee X-ray examination revealed same results.Knee magnetic resonance imaging(MRI)scanning also showed some neo-menisci in PCL-MECM scaffold group.In conclusion,PCL-MECM scaffold appears to optimize meniscus regeneration.This could represent a promising approach worthy of further investigation in preclinical applications. | Weimin Guo Mingxue Chen Zhenyong Wang Yue Tian Jinxuan Zheng Shuang Gao Yangyang Li Yufeng Zheng Xu Li Jingxiang Huang Wei Niu Shuangpeng Jiang Chunxiang Hao Zhiguo Yuan Yu Zhang Mingjie Wang Zehao Wang Jiang Peng Aiyuan Wang Yu Wang Xiang Sui Wenjing Xu Libo Hao Xifu Zheng Shuyun Liu Quanyi Guo | 2021 | Bioactive Materials2021，6，10： | 1 |
| 6 | Significantly enhancing fracture toughness of epoxy composite with promisingγ-FeOOH@Fe_(2)O_(3)hybrid nanoparticles by magnetic field assistance显示文摘The toughening of epoxy resin(EP)and the interlaminar toughening of carbon fiber reinforced composite(CF/EP)laminates have been widely concerned.In this work,the needle-likeγ-FeOOH nanoparticles were prepared by liquid phase deposition-air oxidation method,and then were calcined under different conditions to obtainγ-FeOOH andγ-Fe_(2)O_(3) hybrid nanoparticles(γ-FeOOH@Fe_(2)O_(3)).Effect of calcination condition ofγ-FeOOH@-Fe_(2)O_(3) and magnetic field assistance on fracture toughness(KIC)of EP was systematically investigated.Then the selectedγ-FeOOH@Fe_(2)O_(3) with the best toughening effect were used to improve the mode I interlaminar fracture toughness(GIC)of CF/EP laminate.The resultingγ-FeOOH@Fe_(2)O_(3) have a length of around 1μm,a diameter of around 100 nm and the Ms of 8.99–45.96 emu/g.After calcinated at 250℃ for 1 h,theγ-FeOOH@Fe_(2)O_(3) containing 24 wt%FeOOH and 76 wt%Fe_(2)O_(3) achieved the best toughening effect.Under a magnetic field of 0.09 T,the KIC of theγ-FeOOH@Fe_(2)O_(3)/EP composite(2.45 MPa m^(1/2)) is 81.7%and 66.7%higher than that of neat epoxy and the composite without magnetic field induction,respectively.Furthermore,the GIC of theγ-FeOOH@Fe_(2)O_(3)/CF/EP composite(0.914 kJ/m^(2)) is also significantly increased by 88.8%and 51.8%compared to that of CF/EP and the corresponding composite without magnetic field induction,respectively. | Guan Chen Chuanguo Ma Zehao Fu Jing Wang Peibang Dai | 2022 | Nano Materials Science2022，4，2： | 1 |
| 7 | Homologous gradient heterostructure-based artificial synapses for neuromorphic computation显示文摘Gradient heterostructure is one of fundamental interfaces and provides an effective platform to achieve gradually changed properties in mechanics,optics,and electronics.Among different types of heterostructures,the gradient one may provide multiple resistive states and immobilized conductive fila-ments,offering great prospect for fabricating memristors with both high neuromorphic computation capability and repeatability.Here,we invent a memristor based on a homologous gradient heterostructure(HGHS),compris-ing a conductive transition metal dichalcogenide and an insulating homolo-gous metal oxide.Memristor made of Ta–TaS_(x)O_(y)–TaS 2 HGHS exhibits continuous potentiation/depression behavior and repeatable forward/backward scanning in the read-voltage range,which are dominated by multi-ple resistive states and immobilized conductive filaments in HGHS,respec-tively.Moreover,the continuous potentiation/depression behavior makes the memristor serve as a synapse,featuring broad-frequency response(10^(-1)–10^(5) Hz,covering 106 frequency range)and multiple-mode learning(enhanced,depressed,and random-level modes)based on its natural and moti-vated forgetting behaviors.Such HGHS-based memristor also shows good unifor-mity for 5?7 device arrays.Our work paves a way to achieve high-performance integrated memristors for future artificial neuromorphic computation. | Changjiu Teng Qiangmin Yu Yujie Sun Baofu Ding Wenjun Chen Zehao Zhang Bilu Liu Hui-Ming Cheng | 2023 | InfoMat2023，5，1： | 1 |
| 8 | STUDY ON THE FORMATION OF DEFECTS IN DURALUMIN FORGINGS显示文摘The mechanism of forming defects in 2024. 7075 series aluminium alloy forgings has been studiedby means of metallography. EDAX. SEM etc. The defects are divided into two types by their appearance.needle-shaped and flake-shaped. The mechanism of them forming is discussed. It has been testified that thedefects result from hydrogen or oxide film. The defects can be prevented by controlling the hydrogen contentin the melt and keeping oxide film from involving. | Zhang Shenghua Zhu Xuxia Lin Gaoyong Hu Zehao(Department of Materials Science and Engineering. Central South University ofTechnology, Changsha 410083, China)Deng Dongqiao Yan Wenming Wu Shigao Chen Yishu(Southwest Aluminium Fabrication Plant, Chongq | 1997 | Journal of Central South University1997，9，1： | 0 |
| 9 | Unidirectional Identity-Based Proxy Re-Signature with Key Insulation in EHR Sharing System显示文摘The introduction of the electronic medical record(EHR)sharing system has made a great contribution to the management and sharing of healthcare data.Considering referral treatment for patients,the original signature needs to be converted into a re-signature that can be verified by the new organization.Proxy re-signature(PRS)can be applied to this scenario so that authenticity and nonrepudiation can still be insured for data.Unfortunately,the existing PRS schemes cannot realize forward and backward security.Therefore,this paper proposes the first PRS scheme that can provide key-insulated property,which can guarantee both the forward and backward security of the key.Although the leakage of the private key occurs at a certain moment,the forward and backward key will not be attacked.Thus,the purpose of key insulation is implemented.What’s more,it can update different corresponding private keys in infinite time periods without changing the identity information of the user as the public key.Besides,the unforgeability of our scheme is proved based on the extended Computational Diffie-Hellman assumption in the random oracle model.Finally,the experimental simulation demonstrates that our scheme is feasible and in possession of promising properties. | Yanan Chen Ting Yao Haiping Ren Zehao Gan | 2022 | Computer Modeling in Engineering & Sciences2022，，6： | 0 |
| 10 | Connectivity of fish assemblages along the mangrove-seagrasscoral reef continuum in Wenchang, China显示文摘Understanding the connectivity of fish among different typical habitats is important for conducting ecosystembased management, particularly when designing marine protected areas(MPA) or setting MPA networks. To clarify of connectivity among mangrove, seagrass beds, and coral reef habitats in Wenchang, Hainan Province,China, the fish community structure was studied in wet and dry seasons of 2018. Gill nets were placed across the three habitat types, and the number of species, individuals, and body size of individual fish were recorded. In total, 3 815 individuals belonging to 154 species of 57 families were collected. The highest number of individuals and species was documented in mangroves(117 species, 2 623 individuals), followed by coral reefs(61 species,438 individuals) and seagrass beds(46 species, 754 individuals). The similarity tests revealed highly significant differences among the three habitats. Approximately 23.4% species used two habitats and 11.0% species used three habitats. A significant difference(p<0.05) in habitat use among eight species(Mugil cephalus, Gerres oblongus, Siganus fuscescens, Terapon jarbua, Sillago maculata, Upeneus tragula, Lutjanus russellii, and Monacanthus chinensis) was detected, with a clear ontogenetic shift in habitat use from mangrove or seagrass beds to coral reefs. The similarity indices suggested that fish assemblages can be divided into three large groups namely coral, seagrass, and mangrove habitat types. This study demonstrated that connectivity exists between mangrove–seagrass–coral reef continuum in Wenchang area;therefore, we recommend that fish connectivity should be considered when designing MPAs or MPA network where possible. | Jianguo Du Meiling Xie Yuyu Wang Zehao Chen Wenhua Liu Jianji Liao Bin Chen | 2020 | Acta Oceanologica Sinica2020，39，8： | 0 |
| 11 | GmSAP5,a soybean A20/AN1 domain-containing stress-associated protein gene activated by GmAREB3,increases drought stress resistance in soybean by mediating ABA signaling显示文摘Drought stress impairs crop growth and productivity.Stress-associated proteins(SAPs),a class of zinc finger proteins containing the A20/AN1 domain,function in various stress responses in plants.However,little is known about the function of SAPs in drought-stress responses in soybean,an oil and protein crop.We report that a GmSAP5 protein confers drought tolerance by increasing sensitivity to abscisic acid(ABA)and reducing stomatal aperture.Overexpression and RNA interference of GmSAP5in soybean hairy roots resulted in elevated resistance and sensitivity to drought stress,respectively.ABA and proline contents increased in GmSAP5-overexpressing plants under water-deficit conditions.Lower water loss rates and higher relative water contents were observed in GmSAP5-overexpressing plants,resulting in increased drought-stress resistance.A yeast one-hybrid assay and luciferase transient transcriptional activity assay showed that GmAREB3,an AREB/ABF transcription factor,could bind to the promoter of GmSAP5 and activate its expression.These results suggest that GmSAP5 acts downstream of GmAREB3 and improves drought-stress resistance by mediating ABA signaling. | Zehao Hou Xiangzhan Zhang Yimiao Tang Taifei Yu Lei Zheng Jun Chen Yongbin Zhou Yongwei Liu Ming Chen Zhao-Shi Xu Youzhi Ma | 2022 | The Crop Journal2022，10，6： | 0 |
| 12 | SlMYB72 affects pollen development by regulating autophagy in tomato显示文摘The formation and development of pollen are among the most critical processes for reproduction and genetic diversity in the life cycle of f lowering plants.The present study found that SlMYB72 was highly expressed in the pollen and tapetum of tomato f lowers.Downregulation of SlMYB72 led to a decrease in the amounts of seeds due to abnormal pollen development compared with wild-type plants.Downregulation of SlMYB72 delayed tapetum degradation and inhibited autophagy in tomato anther.Overexpression of SlMYB72 led to abnormal pollen development and delayed tapetum degradation.Expression levels of some autophagy-related genes(ATGs)were decreased in SlMYB72 downregulated plants and increased in overexpression plants.SlMYB72 was directly bound to ACCAAC/ACCAAA motif of the SlATG7 promoter and activated its expression.Downregulation of SlATG7 inhibited the autophagy process and tapetum degradation,resulting in abnormal pollen development in tomatoes.These results indicated SlMYB72 affects the tapetum degradation and pollen development by transcriptional activation of SlATG7 and autophagy in tomato anther.The study expands the understanding of the regulation of autophagy by SlMYB72,uncovers the critical role that autophagy plays in pollen development,and provides potential candidate genes for the production of male-sterility in plants. | Mengbo Wu Qiongdan Zhang Guanle Wu Lu Zhang Xin Xu Xiaowei Hu Zehao Gong Yulin Chen Zhengguo Li Honghai Li Wei Deng | 2023 | Horticulture Research2023，10，3： | 0 |
| 13 | Biomaterials for microfluidic technology显示文摘Micro/nanomaterial-based drug and cell delivery systems play an important role in biomedical fields for their injectability and targeting.Microfluidics is a rapidly developing technology and has become a robust tool for preparing biomaterial micro/nanocarriers with precise structural control and high reproducibility.By flexibly designing microfluidic channels and manipulating fluid behavior,various forms of biomaterial carriers can be fabricated using microfluidics,including microspheres,nanoparticles and microfibers.In this review,recent advances in biomaterials for designing functional microfluidic vehicles are summarized.We introduce the application of natural materials such as polysaccharides and proteins as well as synthetic polymers in the production of microfluidic carriers.How the material properties determine the manufacture of carriers and the type of cargoes to be encapsulated is highlighted.Furthermore,the current limitations of microfluidic biomaterial carriers and perspectives on its future developments are presented. | Zehao Chen Zhendong Lv Zhen Zhang Yuhui Zhang Wenguo Cui | 2022 | Materials Futures2022，1，1： | 0 |
| 14 | Transcutaneous auricular vagus nerve stimulation would be an alternative to implantable cervical vagus nerve stimulation in some situation显示文摘Implantable cervical vagus nerve stimulation(i VNS) is a representative and promising neuromodulation.However,the invasive nature restricts its application.Traditional auricular acupuncture treatment has a long history.The auricular branch of the vagus nerve(ABVN) is a branch on the surface of the ear.Some studies demonstrates that transcutaneous auricular vagus nerve stimulation(ta VNS) would achieve similar effects as i VNS.Ta VNS and i VNS share a common anatomical basis and acting mechanism.In this article,we made a comparison between i VNS and ta VNS in indications and efficacy.The recent studies have revealed similar clinical efficacy of ta VNS,ta VNS would expand the indication of i VNS.Highquality clinical evidences are needed before ta VNS become be an alternative of i VNS. | HE Jiakai ZHANG Jinling WANG Yu LI Shaoyuan FANG Jiliang ZHANG Shuai ZHAO Yanan ZHAI Weihang GAO Deqiang LI Ran JIANG Yuhang CHEN Zehao JIA Baohui RONG Peijing | 2023 | Journal of Traditional Chinese Medicine2023，43，3： | 0 |
| 15 | Interface Engineering and Anion Engineering of Mo-Based Heterogeneous Electrocatalysts for Hydrogen Evolution Reaction显示文摘Development and utilization of hydrogen energy is an effective way to achieve carbon neutrality,only hydrogen production through electrolytic water splitting meets the goal of zero carbon emission.To facilitate the large-scale commercialization of water splitting devices,the development of highly efficient and low-cost catalysts to reduce the energy consumption is essential.MoS_(2)has been regarded as a promising electrocatalyst to replace platinum in hydrogen evolution reaction due to its low price and unique 2D layered structure.However,the poor conductivity and inert basal planes of MoS_(2)limited its wide-spread application.Recently,researches have demonstrated that the conductivity and active sites of MoS_(2)can be improved by heteroatoms doping or constructing of heterogeneous structures.In this review,the recent progress of Mo-based catalysts are summarized centered on MoS_(2)based on interface engineering and anion engineering,including MoS_(2)–MoO_(2),MoS_(2)–Mo_(2)C,MoS_(2)–MoN_(x),MoS_(2)–MoP,and MoS_(2)–MoSe_(2).The preparation method,structure,and performance of the catalysts are introduced and the possible mechanism behind the improved catalytic activity are revealed to give readers an overall comprehension on the progress of the Mo-based electrocatalysts for hydrogen evolution reaction.In addition,an outlook on future opportunities and development directions of Mo-based catalysts are proposed to facilitate the development of Mo-based catalysts for hydrogen production. | Zehao Yin Xuan Liu Siru Chen Tingli Ma Yanqiang Li | 2023 | Energy & Environmental Materials2023，6，1： | 0 |
| 16 | Complications Following Facial Thread-Lifting显示文摘Background Facial thread-lifting(FTL)is a minimally invasive facial rejuvenation technique.However,to date,no study has focused on the treatment of complications associated with FTL.The purpose of this study was to report on clinical manifestations of complications following FTL and their treatment methods.Methods We retrospectively reviewed the electronic medical records of patients who presented with complications of FTL.Patient demographics,medical history,types and clinical manifestations of complications,imaging,treatment methods,histopathological findings,and follow-up information were collected.Descriptive statistical analysis was performed.Results Our sample included 61 patients,all women,with a mean age of 36.3±8.9 years.The most common reason for consultation was infection(31.2%),followed by dissatisfaction with postoperative facial contour(23%),paresthesia(19.7%),dimpling and irregularity(16.4%),subcutaneous induration(13.1%),thread extrusion(4.9%),and facial nerve injury(3.3%).Fifty-one(83.6%)patients reported alleviated symptoms after receiving pharmaceutical and physical therapies.Surgical interventions,including debridement and thread removal,were required in 10 patients(16.4%).Threads were completely or partially removed in 5 patients within 3 months of the initial FTL.During a median follow-up of 1.7 years,9 patients recovered well and were satisfied with the clinical outcomes,whereas one patient was unsatisfied due to dimpling and scarring.Conclusions The results show that most complications after FTL can be treated nonsurgically.Revision surgery is recommended for patients with recurrent infection,thread extrusion,and subcutaneous induration.Aesthetic surgeons and dermatologists should comply with the indications for FTL and optimize surgical procedures to minimize the risk of complications. | Zehao NIU Yudi HAN Rui JIN Yan LI Jianchao LIU Nan LI Wanheng LI Dan LI Youbai CHEN Yan HAN | 2020 | Chinese Journal Of Plastic and Reconstructive Surgery2020，2，4： | 0 |
| 17 | Development of fish collagen in tissue regeneration and drug delivery显示文摘Tissues rely on collagen for structural and biological integrity,as well as for function and strength.Several collagen sources have been investigated due to its wide variety of applications,such as collagen from cows and pigs.However,mammalian-based collagen has been limited by diseases like bovine spongiform encephalopathy(BSE)and other religious limitations.Hence,fish collagen has caught the attention of the research community because it is easy to extract,has a high level of collagen content,excellent absorption properties,a low molecular weight,biocompatibility,little risk of disease transmission from animals to humans,negligible environmental contamination,and fewer ethical and religious concerns,posing as an ideal resource for product development.This review focuses on the growing role of marine collagen in the advances of various biomedical applications,such as drug delivery,tissue engineering,regeneration,and wound healing,which will be covered in depth. | Meison Furtado Liang Chen Zehao Chen Ao Chen Wenguo Cui | 2022 | Engineered Regeneration2022，3，3： | 0 |
| 18 | Exploration of the oxygen transport behavior in non-precious metal catalyst-based cathode catalyst layer for proton exchange membrane fuel cells显示文摘High cost has undoubtedly become the biggest obstacle to the commercialization of proton exchange membrane fuel cells(PEMFCs),in which Pt-based catalysts employed in the cathodic catalyst layer(CCL)account for the major portion of the cost.Although nonprecious metal catalysts(NPMCs)show appreciable activity and stability in the oxygen reduction reaction(ORR),the performance of fuel cells based on NPMCs remains unsatisfactory compared to those using Pt-based CCL.Therefore,most studies on NPMC-based fuel cells focus on developing highly active catalysts rather than facilitating oxygen transport.In this work,the oxygen transport behavior in CCLs based on highly active Fe-N-C catalysts is comprehensively explored through the elaborate design of two types of membrane electrode structures,one containing low-Pt-based CCL and NPMCbased dummy catalyst layer(DCL)and the other containing only the NPMC-based CCL.Using Zn-N-C based DCLs of different thickness,the bulk oxygen transport resistance at the unit thickness in NPMC-based CCL was quantified via the limiting current method combined with linear fitting analysis.Then,the local and bulk resistances in NPMC-based CCLs were quantified via the limiting current method and scanning electron microscopy,respectively.Results show that the ratios of local and bulk oxygen transport resistances in NPMCbased CCL are 80%and 20%,respectively,and that an enhancement of local oxygen transport is critical to greatly improve the performance of NPMC-based PEMFCs.Furthermore,the activity of active sites per unit in NPMCbased CCLs was determined to be lower than that in the Pt-based CCL,thus explaining worse cell performance of NPMC-based membrane electrode assemblys(MEAs).It is believed that the development of NPMC-based PEMFCs should proceed not only through the design of catalysts with higher activity but also through the improvement of oxygen transport in the CCL. | Shiqu CHEN Silei XIANG Zehao TAN Huiyuan LI Xiaohui YAN Jiewei YIN Shuiyun SHEN Junliang ZHANG | 2023 | Frontiers in Energy2023，17，1： | 0 |
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