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| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | Preparation of nanometer FeCuP alloy and its application in decomposition of PH3显示文摘使用分解 PH3 的新第三的基于 Fe 的合金催化剂 FeCuP 被化学减小免职方法与便宜材料准备。它的性质被 XRD, ICP 和 SEM 描绘。它 PH3 和分解条件的分解上的催化活动被学习。FeCuP 合金展出高热的稳定性和高催化的活动。把它用作催化剂,到 400 500 ° C 的从超过 800 ° C 的磷化氢减少的分解温度。磷化氢的分解率完成了 100% 。 | Chang Xiu Han Ji Li Ren Xue Jiao Tang Bao Gui Zhang | 2007 | Chinese Chemical Letters2007，18，10： | 8 |
| 3 | Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes显示文摘Objective: There are no comprehensive studies on survival outcomes and optimal treatment protocols for cervical esophageal cancer(CEC), due to its rare clinical prevalence. Our objective was to determine the relationship between pathological characteristics, treatment protocols, and survival outcomes in Chinese CEC patients.Methods: A total of 500 Chinese CEC patients were selected from our 500,000 esophageal and gastric cardia carcinoma database(1973–2018). There were two main groups: patients treated with surgery, and patients receiving non-surgical treatments(radiotherapy, radiochemotherapy, and chemotherapy). The Chi-square test and Kaplan–Meier method were used to compare the continuous variables and survival.Results: Among the 500 CEC patients, 278(55.6%) were male, and the median age was 60.9 ± 9.4 years. A total of 496 patients(99.2%) were diagnosed with squamous cell carcinoma. In 171(34.2%) patients who received surgery, 22(12.9%) had undergone laryngectomy. In 322(64.4%) patients who received non-surgical treatments, 245(76.1%) received radiotherapy. Stratified survival analysis showed that only T stage was related with survival outcomes for CEC patients in the surgical group, and the outcomes between laryngectomy and non-laryngectomy patients were similar. It was noteworthy that the 5-year survival rate was similar in CEC patients among the different groups treated with surgery, radiotherapy, chemotherapy, or radiochemotherapy(P = 0.244). Conclusions: The CEC patients had similar survival outcomes after curative esophagectomy and radiotherapy, including those with or without total laryngectomy. These findings suggest that radiotherapy could be the initial choice for treatment of Chinese CEC patients. | Peinan Chen Xueke Zhao Fuyou Zhou Xin Song Shoujia Hu Yan Jin Xianzeng Wang Xuena Han ZongminFan Ran Wang Bei Li Wenli Han Panpan Wang Jilin Li Lixin Wan Liguo Zhang Qide Bao Fubao Chang Yanru Qin Zhiwei Chang Jianwei Ku Haijun Yang Ling Yuan Jingli Ren Xuemin Li Lidong Wang | 2020 | Cancer Biology & Medicine2020，17，1： | 6 |
| 4 | Triboelectrification induced UV emission from plasmon discharge显示文摘紫外有的高精力的电磁的放射广泛地在工业生产和科学研究领域被使用。在这个工作,深紫外的轻排出物用 triboelectrification 被获得没有任何额外的电源供应的导致的血浆分泌物。由在聚合物和石英玻璃之间的机械磨擦,摩擦电费用引起一个变化电场,它可以带低压力气体(Ar-Hg ) 的血浆分泌物并且给出 253.7 nm 照耀。连续磨擦引起的紫外光能使三色的黄磷激动并且负担得起明亮白的轻排出物。一个紫外消毒实验证明 98% Escherichia coli 能被紫外照耀在 30 min 打死,它表明有好消毒效果的一台自我动力的消毒仪器被制作。这个工作提供一个新奇图案用低频率的机械磨擦制作一台自我动力的紫外轻射出设备并且认识到联合 triboelectrification 和血浆光,它可以进一步在特殊情形扩展紫外光的申请。 | Chang Bao Han Chi Zhang Jingjing Tian Xiaohui Li Limin Zhang Zhou Li Zhong Lin Wang | 2015 | Nano Research2015，8，1： | 5 |
| 5 | Cylindrical spiral triboelectric nanogenerator显示文摘在最近的年里,因为他们的唯一的潜力,摩擦电 nanogenerators 在自我动力的 nanosensors 和 nanosystems 吸引了许多注意。在这份报纸,我们报导圆柱的螺线摩擦电 nanogenerator (S-TENG ) ,它能不仅生产高电的输出到力量显示设备,而且能被用作在一个测量统治者上综合的一个自我动力的排水量传感器。以 2.5 m/s 的滑动速度, S-TENG 能产生电线走火水流(我 30 楣楰慴楴湯焠慵瑮瑩瑡癩汥? 敲潭敶 ? 污 ? 浩異楲楴獥映潲 ? 潣汬楯慤? 潳畬楴湯 ? 景 ? 卤 ? 湡 ? 的 SC ) 摃 ? 慮潮牣獹慴獬挠慯整 ? 楷桴愠瘠牡敩祴漠 ? 慣'R 硯汹瑡 ?楬慧摮 | Xiao Hui Li Chang Bao Han Li Min Zhang Zhong Lin Wang | 2015 | Nano Research2015，8，10： | 4 |
| 6 | Triboelectric nanogenerator enhanced multilayered antibacterial nanofiber air filters for efficient removal of ultrafine particulate matter显示文摘我们开发了 multilayered 抗菌剂 polyimide (PI ) nanofiber 空气为把极其细小的微粒物质(下午) 从周围的空气移开过滤的提高的高效率的旋转摩擦电 nanogenerator (R-TENG ) 。比作单人赛分层的 PI nanofiber 过滤器, multilayered nanofiber 过滤器能完全与比 0.54 m 大的直径粒子移开所有,表演为更小的下午粒子提高移动效率。在与 aR-TENG 连接以后,为极其细小的粒子的 filer 的移动效率进一步被提高。为极其细小的微粒物质的最高的移动效率在 53.3 nm 的直径是 94.1% ,平均移动效率到达 89.9% 。尽管有层数字的增加,这部电影的每单个层的厚度减少了,并且因此,过滤器的全部的压力落下减少了而不是增加。而且,因为银 nanoparticles 的小数量的增加, nanofiber 电影展出了高抗菌剂活动。有零个臭氧版本和低压力落下的这种技术为清洗空气,薄雾处理,和细菌的控制是适当的。 | Guang Qin Gu Chang Bao Han Jing Jing Tian Tao Jiang Chuan He Cun Xin Lu Yu Bai Jin Hui Nie Zhou Li Zhong Lin Wang | 2018 | Nano Research2018，11，8： | 4 |
| 7 | Integrative square-grid triboelectric nanogenerator as a vibrational energy harvester and impulsive force sensor显示文摘方形格子的摩擦电 nanogenerator (SG-TENG ) 为收获震动的精力并且察觉到冲动的力量被表明。每个广场三维(3D ) 打印了方形的格子充满铝(艾尔) 球。格子结构允许 SG-TENG 在宽广带宽上收获震动的精力并且在不同震动的角度操作。SG-TENG 的最惹人注目的特征是它被放大的能力并且综合。在在平行连接二 SG-TENGs 以后,开电路的电压和电线走火电流显著地在完整的震动的频率范围上被增加。与一个乒乓球球拍是综合的, SG-TENG 能从用球拍击一个砰恶臬球收获震动的精力,在由球拍的直接命中产生一般水准的地方,输出 10.9 | Chuan He Weijun Zhu Guang Qin Gu Tao Jiang Liang Xu Bao Dong Chen Chang Bao Han Dichen Li Zhong Lin Wang | 2018 | Nano Research2018，11，2： | 3 |
| 8 | A novel photo-initiated approach for preparing aluminum diethylphosphinate under atmospheric pressure显示文摘铝 diethylphosphinate (AlPi ) 的新奇准备与免费激进分子的增加反应被执行借助于在气压下面紫外照耀。钠次磷酸盐的一个答案与乙烯被对待并且面对有效的 photoinitiator 的数量与紫外光照耀开始在次磷酸盐阴离子和乙烯分子的双契约之间的免费激进分子的反应。乙烯在 gasliquid 接口是微水泡的进有 photoinitiator,和 gasliquid 接触表面和 photoinitiator 集中的增加的反应混合大部分被增加。最后的产品的收益能被改进到大约 96% 。P 的内容,在样品的艾尔被 ICP,和样品的分子的结构检测被 31P NMR, 1H NMR 和 FTIR 证实分光镜的分析。最后的产品的热稳定性被 TGDTA 详细调查。 | Li Yang Xin Yu Han Xue Jiao Tang Chang Xiu Han Yi Xiao Zhou Bao Gui Zhang | 2011 | Chinese Chemical Letters2011，22，4： | 1 |
| 9 | Crohn disease of small bowel: multidetector row CT with CT enteroclysis, dynamic contrast enhancement, CT angiography, and 3D imaging显示文摘 | Yu Bao Liu Chang Hong Liang Zhong Lin Zhang Biao Huang Han Bin Lin Yuan Xin Yu Shu Fei Xie Qiu Shi Wang Jun Hui Zheng | 2006 | Abdominal Imaging2006，，6： | 1 |
| 10 | Simultaneous removal of hydrogen sulfide and mercury from simulated syngas by iron-based sorbents显示文摘 | WANG J C ZHANG Y P HAN L N CHANG L P BAO W R | 2013 | Fuel2013，103，： | 1 |
| 11 | Co‑packaged optics(CPO):status,challenges,and solutions显示文摘Due to the rise of 5G,IoT,AI,and high-performance computing applications,datacenter trafc has grown at a compound annual growth rate of nearly 30%.Furthermore,nearly three-fourths of the datacenter trafc resides within datacenters.The conventional pluggable optics increases at a much slower rate than that of datacenter trafc.The gap between application requirements and the capability of conventional pluggable optics keeps increasing,a trend that is unsustainable.Copackaged optics(CPO)is a disruptive approach to increasing the interconnecting bandwidth density and energy efciency by dramatically shortening the electrical link length through advanced packaging and co-optimization of electronics and photonics.CPO is widely regarded as a promising solution for future datacenter interconnections,and silicon platform is the most promising platform for large-scale integration.Leading international companies(e.g.,Intel,Broadcom and IBM)have heavily investigated in CPO technology,an inter-disciplinary research feld that involves photonic devices,integrated circuits design,packaging,photonic device modeling,electronic-photonic co-simulation,applications,and standardization.This review aims to provide the readers a comprehensive overview of the state-of-the-art progress of CPO in silicon platform,identify the key challenges,and point out the potential solutions,hoping to encourage collaboration between diferent research felds to accelerate the development of CPO technology. | Min Tan Jiang Xu Siyang Liu Junbo Feng Hua Zhang Chaonan Yao Shixi Chen Hangyu Guo Gengshi Han Zhanhao Wen Bao Chen Yu He Xuqiang Zheng Da Ming Yaowen Tu Qiang Fu Nan Qi Dan Li Li Geng Song Wen Fenghe Yang Huimin He Fengman Liu Haiyun Xue Yuhang Wang Ciyuan Qiu Guangcan Mi Yanbo Li Tianhai Chang Mingche Lai Luo Zhang Qinfen Hao Mengyuan Qin | 2023 | Frontiers of Optoelectronics2023，16，1： | 1 |
| 12 | Dual-functional MnS_(2)/MnO_(2) heterostructure catalyst for efficient acidic hydrogen evolution reaction and assisted degradation of organic wastewater显示文摘The design and synthesis of non-precious metal dual-functional electrocatalysts through the modulation of electronic structure are important for the development of renewable hydrogen energy.Herein,MnS_(2)/MnO_(2)-CC heterostructure dual-functional catalysts with ultrathin nanosheets were prepared by a twostep electrodeposition method for efficient acidic hydrogen evolution reaction(HER) and degradation of organic wastewater(such as methylene blue(MB)).The electronic structure of Mn atoms at the MnS_(2)/MnO_(2)-CC heterostructure interface is reconfigured under the joint action of S and O atoms.Theoretical calculations show that the Mn d-band electron distribution in MnS_(2)/MnO_(2)-CC catalyst has higher occupied states near the Fermi level compared to the MnO_(2) and MnS_(2) catalysts,which indicates that MnS_(2)/MnO_(2)-CC catalyst has better electron transfer capability and catalytic activity.The MnS_(2)/MnO_(2)-CC catalysts require overpotential of only 66 and 116 mV to reach current density of 10 and 100 mA cm^(-2)in MB/H_(2)SO_(4) media.The MnS_(2)/MnO_(2)-CC catalyst also has a low Tafel slope(26.72 mV dec^(-1)) and excellent stability(the performance does not decay after 20 h of testing).In addition,the MB removal efficiency of the MnS_(2)/MnO_(2)-CC catalyst with a better kinetic rate(0.0226) can reach 97.76%,which is much higher than that of the MnO_(x)-CC catalyst(72.10%).This strategy provides a new way to develop efficient and stable non-precious metal dual-functional electrocatalysts for HER and organic wastewater degradation. | Wen Kang Zhao Zi Qiang Ma Jia Yu Zheng Chang Bao Han Kai Ling Zhou Ming Yang Hao De Cai Fang Yi Xia Hui Yan | 2023 | Journal of Energy Chemistry2023，，12： | 0 |
| 13 | Evaluation of Related Traits of GmTST2.1 and ZmGIF1 Genes in Soybean (Glycine Max)显示文摘Soybean(Glycine max)is one of the most important food crops and oil crops in the world.According to the role of sucrose transporter in sugar accumulation,GmTST2.1(Glyma.04G000300)and ZmGIF1 of sugar transport related genes were separately overexpressed in the soybean cultivar Heihe 43 from the perspective of regulatory source to library relationship in the study.The function of soluble sugar accumulation in grains layed a theoretical foundation for the cultivation of new varieties of high-yield genetically modified soybeans.The results showed that the height and 100-seed weight of the over-expressed GmTST2.1 gene were increased with 7%and 17.7%and the soluble sugar content was increased with 1.575 times as much as that of the wild-type soybean.The overexpressed ZmGIF1 gene was found to be 10%higher than that of plant height,1.8%higher than that of 100-seed weight and larger seed size and 1.3 times higher than that of soluble sugar content.Biological yields were increased in both GmTST2.1 and ZmGIF1 genes. | Dong Hai-ran Chang Hong Wang Jun Bao Dong-fang Zhao Xue Han Ying-peng | 2020 | Journal of Northeast Agricultural University(English Edition)2020，27，4： | 0 |
| 14 | Non-coding RNAs expression in SARS-CoV-2 infection:pathogenesis,clinical significance,and therapeutic targets显示文摘The coronavirus disease 2019(COVID-19)pandemic has been looming globally for three years,yet the diagnostic and treatment methods for COVID-19 are still undergoing extensive exploration,which holds paramount importance in mitigating future epidemics.Host non-coding RNAs(ncRNAs)display aberrations in the context of COVID-19.Specifically,microRNAs(miRNAs),long non-coding RNAs(lncRNAs),and circular RNAs(circRNAs)exhibit a close association with viral infection and disease progression.In this comprehensive review,an overview was presented of the expression profiles of host ncRNAs following SARS-CoV-2 invasion and of the potential functions in COVID-19 development,encompassing viral invasion,replication,immune response,and multiorgan deficits which include respiratory system,cardiac system,central nervous system,peripheral nervous system as well as long COVID.Furthermore,we provide an overview of several promising host ncRNA biomarkers for diverse clinical scenarios related to COVID-19,such as stratification biomarkers,prognostic biomarkers,and predictive biomarkers for treatment response.In addition,we also discuss the therapeutic potential of ncRNAs for COVID-19,presenting ncRNA-based strategies to facilitate the development of novel treatments.Through an in-depth analysis of the interplay between ncRNA and COVID-19 combined with our bioinformatic analysis,we hope to offer valuable insights into the stratification,prognosis,and treatment of COVID-19. | Xiaoxing Liu Wandi Xiong Maosen Ye Tangsheng Lu Kai Yuan Suhua Chang Ying Han Yongxiang Wang Lin Lu Yanping Bao | 2024 | Signal Transduction and Targeted Therapy2024，9，1： | 0 |
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