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| 1 | Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress显示文摘癌症房间以他们的能力著名给新陈代谢的小径换新电线在各种各样的压力条件下面支持幸存和增长。尽管在肝生产了,酉同类身体没在正常的成年的肝房间被消费。我们这里发现酉同类分解代谢或 ketolysis 在 hepatocellular 被重新激活在营养剥夺条件下面的癌(HCC ) 房间。机械学地, 3-oxoacid CoA-transferase 1 (OXCT1 ) ,其表情在正常的成年的肝纸巾被压制的限制率的 ketolytic 酶,被浆液重新导致被触发饥饿的 mTORC2-AKT-SP1 在 HCC 房间发信号。而且,我们观察到在 HCC 的那提高的 ketolysis 为 AMPK 激活的压抑是批评的并且保护 HCC 房间免受过多的 autophagy 的伤害,从而提高肿瘤生长。重要地,临床的 HCC 样品的分析表明那增加的 OXCT1 表情预言更高耐心的死亡。一起拿,我们这里揭开剥夺营养的 HCC 房间为精力由采用酉同类身体的新奇新陈代谢的改编供应和癌症前进。 | De Huang Tingting Li Lin Wang Long Zhang Ronghui Yan Kui Li Songge Xing Gongwei Wu Lan Hu Weidong Jia Sheng-Cai Lin Chi V Dang Libing Song Ping Gao Huafeng Zhang | 2016 | Cell Research2016，26，10： | 27 |
| 2 | MYC on the Path to Cancer显示文摘 | Chi V. Dang | 2012 | Cell2012，，1： | 6 |
| 3 | Control of T H 17/T reg Balance by Hypoxia-Inducible Factor 1显示文摘 | Eric V. Dang Joseph Barbi Huang-Yu Yang Dilini Jinasena Hong Yu Ying Zheng Zachary Bordman Juan Fu Young Kim Hung-Rong Yen Weibo Luo Karen Zeller Larissa Shimoda Suzanne L. Topalian Gregg L. Semenza Chi V. Dang Drew M. Pardoll Fan Pan | 2011 | Cell2011，，5： | 3 |
| 4 | Ecoregional variations of aboveground biomass and stand structure in evergreen broadleaved forests显示文摘Biotic and abiotic factors control aboveground biomass(AGB)and the structure of forest ecosystems.This study analyses the variation of AGB and stand structure of evergreen broadleaved forests among six ecoregions of Vietnam.A data set of 1731-ha plots from 52 locations in undisturbed old-growth forests was developed.The results indicate that basal area and AGB are closely correlated with annual precipitation,but not with annual temperature,evaporation or hours of sunshine.Basal area and AGB are positively correlated with trees>30 cm DBH.Most areas surveyed(52.6%)in these old-growth forests had AGB of 100–200 Mg ha^-1;5.2%had AGB of 400–500 Mg ha^-1,and 0.6%had AGB of>800 Mg ha^-1.Seventy percent of the areas surveyed had stand densities of 300–600 ind.ha^-1,and 64%had basal areas of 20–40 m^2 ha^-1.Precipitation is an important factor influencing the AGB of old-growth,evergreen broadleaved forests in Vietnam.Disturbances causing the loss of large-diameter trees(e.g.,>100 cm DBH)affects AGB but may not seriously affect stand density. | Tran Van Do Mamoru Yamamoto Osamu Kozan Vo Dai Hai Phung Dinh Trung Nguyen Toan Thang Lai Thanh Hai Vu Thanh Nam Trieu Thai Hung Hoang Van Thang Tran Duc Manh Cao Chi Khiem Vu Tien Lam Nguyen Quang Hung Tran Hoang Quy Pham Quang Tuyen Trinh Ngoc Bon Nguyen Thi Thu Phuong Ninh Viet Khuong Nguyen Van Tuan Dang Thi Hai Ha Tran Hai Long Dang Van Thuyet Dang Thinh Trieu Nguyen Van Thinh Tran Anh Hai Duong Quang Trung Nguyen Van Bich Dinh Hai Dang Pham Tien Dung Nguyen Huy Hoang Le Thi Hanh Phan Minh Quang Nguyen Thi Thuy Huong Hoang Thanh Son Nguyen Thanh Son Nguyen Thi Van Anh Nguyen Thi Hoai Anh Pham Dinh Sam Hoang Thi Nhung Hoang Van Thanh Nguyen Huu Thinh Tran Hong Van Ho Trung Luong Bui Kieu Hung | 2020 | Journal of Forestry Research2020，31，5： | 1 |
| 5 | Six-DOF micro-manipu- lator based on compliant parallel mechanism with integrated force sensor 显示文摘 | Qiaokang Liang Dang Zhang Zhongzhe Chi | 2010 | Robotics and Computer-Integrated Manufacturing2010，27，1： | 1 |
| 6 | Stimulation of tetanus toxoid - specific immune responses by a tradition-al Chinese herbal medicine显示文摘 | UNDERWOOD J R CHI VERS M DANG T T | 2009 | Vaccine2009，27，47： | 1 |
| 7 | Identification of zinc-binding peptides in ADAM17-inhibiting whey protein hydrolysates using IMAC-Zn^(2+) coupled with shotgun peptidomics显示文摘Food components possessing zinc ligands can be used to inhibit zinc-dependent enzymes.In this study,zinc-binding peptides were derived from whey protein hydrolysates,and their ultrafiltration(>1 and<1 kDa)fractions,produced with Esperase(WPH-Esp),Everlase and Savinase.Immobilized metal affinity chromatography(IMAC-Zn^(2+))increased the zinc-binding capacity of the peptide fraction(83%)when compared to WPH-Esp(23%)and its<1 kDa fraction(40%).The increased zinc-binding capacity of the sample increased the inhibitory activity against the zinc-dependent“a disintegrin and metalloproteinase 17”.LC-MS/MS analysis using a shotgun peptidomics approach resulted in the identification of 24 peptides originating from bovineβ-lactoglobulin,α-lactalbumin,serum albumin,β-casein,κ-casein,osteopontin-k,and folate receptor-αin the fraction.The identified peptides contained different combinations of the strong zinc-binding group of residues,His+Cys,Asp+Glu and Phe+Tyr,although Cys residues were absent in the sequences.In silico predictions showed that the IMAC-Zn^(2+)peptides were non-toxins.However,the peptides possessed poor drug-like and pharmacokinetic properties;this was possibly due to their long chain lengths(5–19 residues).Taken together,this work provided an array of food peptide-based zinc ligands for further investigation of structure-function relationships and development of nutraceuticals against inflammatory and other zinc-related diseases. | M.Chinonye Udechukwu Chi Dang Chibuike C.Udenigwe | 2021 | Food Production, Processing and Nutrition2021，3，1： | 1 |
| 8 | High energy and high brightness laser compton backscattering gamma-ray source at IHEP显示文摘Based on the LINAC of BEPCII, a high-polarized, high bightness, energy-tunable, monoenergetic laser compton backscattering (LCS)gamma-ray source is under construction at IHEP. The gamma-ray energy range is from 1 MeV to 111 MeV. It is a powerful and hopeful researchplatform to reveal the underlying physics of the nuclear, the basic particles and the vacuum or to check the exist basic physical models, quantumelectrodynamic (QED) theories. In the platform, a 1.064 mm Nd:YAG laser system and a 10.6 mm CO_(2) laser system are employed. All the triggersignals to the laser system and the electron control system are from the only reference clock at the very beginning of the LINAC to make sure thetemporal synchronization. Two optical transition radiation (OTR) targets and two charged-couple devices (CCD) are used to monitor and to alignthe electron beam and the laser beam. With the LCS gamma-ray source, it is proposed to experimentally check the gamma-ray calibrations, thephoton-nuclear physics, nuclear astrophysics and some basic QED phenomena. | Guang-Peng An Yun-Long Chi Yong-Le Dang Guang-Yong Fu Bing Guo Yong-Sheng Huang Chuang-Ye He Xiang-Cheng Kong Xiao-Fei Lan Jia-Cai Li Fu-Long Liu Jin-Shui Shi Xian-Jing Sun Yi Wang Jian-Li Wang Lin Wang Yuan-Yuan Wei Gang Wu Guang-Lei Xu Xiao-Feng Xi Guo-Jun Yang Chun-Lei Zhang Zhuo Zhang Zhi-Peng Zheng Xiao-Ding Zhang Shao-Ping Zhang | 2018 | Matter and Radiation at Extremes2018，3，4： | 1 |
| 9 | Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC显示文摘 | Wei Liu Anne Le Chad Hancock Andrew N. Lane Chi V. Dang Teresa W.-M. Fan James M. Phang | 2012 | Proceedings of the National Academy of Sciences2012，，23： | 1 |
| 10 | Effects of hypoxia on tumor metabolism 显示文摘 | Jung-whan Kim Ping Gao Chi V Dang | 2007 | Cancer Metastasis Rev2007，26，： | 1 |
| 11 | Oncogenic alterations of metabolism显示文摘 | Chi V Dang Gregg L Semenza | 1999 | Trends in Biochemical Sciences1999，，2： | 1 |
| 12 | Six - DOF micro - ma- nipulator based on compliant parallel mechanism with intega'ated force sen- sor显示文摘 | Liang Qiaokang Zhang Dang Chi Zhongzhe | 2010 | Robotics and Computer - Integrated Manufacturing2010，，2： | 1 |
| 13 | Surface molecular doping of all-inorganic perovskite using zethrenes molecules显示文摘We present an optical and photoelectron spectroscopic study to elucidate the interfacial electronic properties of organic-inorganic semiconductor heterojunctions formed in a kinetically blocked heptazethrene triisopropylsilyl ethynylene (HZ-TIPS) and its homologue,octazethrene (OZ-TIPS) on an all-inorganic perovskite cesium lead bromide (CsPbBr3) surface.The photoluminescence behavior of the underlying perovskites upon differing molecular doping conditions was examined.It turns out that the charge transfer dynamics of thermally-evaporated OZ-TIPS molecule exhibited a faster average lifetime than that of the HZ-TIPS case suggesting the importance of the biradical state in the former molecule.An interfacial dipole was formed at the interface due to the competing interaction between the dispersion force of the bulky TIPS-substituent group and the attractive van der Waals interaction at the first few layers.Photoemission spectroscopy of the physisorbed HZ-TIPS shows chemical shifts,which indicates electron transfer from HZ-TIPS molecules to the CsPbBr3 perovskite single crystal.In contrast,the adsorbed OZ-TIPS molecular layer on CsPbBr3 demonstrates the opposite trend indicating a hole transfer process.The average molecular orientation as determined by near edge X-ray absorption fine structure (NEXAFS) suggests that the HZ-TIPS molecular plane is generally lifted with respect to the perovskite surface.We suggest that the nature of the closed-shell electronic ground state of HZ-TIPS could contribute to the formation of interfacial dipole at the molecule/perovskite interface. | Arramel Hu Pan Aozhen Xie Songyan Hou Xinmao Yin Chi Sin Tang Nguyen T.Hoa Muhammad D.Birowosuto Hong Wang Cuong Dang Andrivo Rusydi Andrew T.S.Wee Jishan Wu | 2019 | Nano Research2019，12，1： | 1 |
| 14 | Corrosion behavior of ship' s ballast tank in sodium hypochtorite treated ballast water显示文摘 | SONG Yongxin DANG Kun CHI Huafang | 2006 | J Harbin Eng Univ2006，27，2： | 1 |
| 15 | Oncogenic alterations of metabolism显示文摘 | Chi V Dang Gregg L Semenza | 1999 | Trends in Biochemical Sciences1999，，2： | 1 |
| 16 | Synthesis, photophysical and electroluminescent properties of novel iridium (III) complexes based on 5-methyl-2- phenylbenzooxazole derivatives显示文摘 | Li X Chi H J Dang Y | 2013 | Opt Mater2013，36，2： | 1 |
| 17 | Genome assembly of wild loquat (Eriobotrya japonica) and resequencing provide new insights into the genomic evolution and fruit domestication in loquat显示文摘Wild loquats(Eriobotrya japonica Lindl.)provide remarkable genetic resources for studying domestication and breeding improved varieties.Herein,we generate the first high-quality chromosome-level genome assembly of wild loquat,with 45791 predicted proteincoding genes.Analysis of comparative genomics indicated that loquat shares a common ancestor with apple and pear,and a recent whole-genome duplication event occurred in loquat prior to its divergence.Genome resequencing showed that the loquat germplasms can be distinctly classified into wild and cultivated groups,and the commercial cultivars have experienced allelic admixture.Compared with cultivated loquats,the wild loquat genome showed very few selected genomic regions and had higher levels of genetic diversity.However,whole-genome scans of selective sweeps were mainly related to fruit quality,size,and f lesh color during the domestication process.Large-scale transcriptome and metabolome analyses were further performed to identify differentially expressed genes(DEGs)and differentially accumulated metabolites(DAMs)in wild and cultivated loquats at various fruit development stages.Unlike those in wild loquat,the key DEGs and DAMs involved in carbohydrate metabolism,plant hormone signal transduction,f lavonoid biosynthesis,and carotenoid biosynthesis were significantly regulated in cultivated loquats during fruit development.These high-quality reference genome,resequencing,and large-scale transcriptome/metabolome data provide valuable resources for elucidating fruit domestication and molecular breeding in loquat. | Danlong Jing Xinya Liu Qiao He Jiangbo Dang Ruoqian Hu Yan Xia Di Wu Shuming Wang Yin Zhang Qingqing Xia Chi Zhang Yuanhui Yu Qigao Guo Guolu Liang | 2023 | Horticulture Research2023，10，2： | 0 |
| 18 | Green synthesis of three-dimensional magnesium ferrite/titanium dioxide/reduced graphene from Garcinia mangostana extract for crystal violet photodegradation and antibacterial activity显示文摘In this study,three-dimensional porous magnesium ferrite/titanium dioxide/reduced graphene oxide(Mg Fe_2O_(4)-GM/TiO_(2)/rGO(MGTG))was successfully synthesized via green and hydrothermal-supported co-precipitation methods using the extract of Garcinia mangostana(G.mangostana)as a reducing agent.The characterization results indicate the successful formation of the nano/micro Mg Fe_(2)O_(4)(MFO)and TiO_(2) on the structure of the reduced graphene oxide(rGO),which can also act as efficient support,alleviating the agglomeration of the nano/micro MFO and TiO_(2).The synergic effects of the adsorption and photodegradation activity of the material were investigated according to the removal of crystal violet(CV)under ultraviolet light.The effects of catalyst dosage,CV concentration,and p H on the CV removal efficiency of the MGTG were also investigated.According to the results,the CV photodegradation of the MGTG-200 corresponded to the pseudo-first-order kinetic model.The reusability of the material after 10 cycles also showed a removal efficiency of 92%.This happened because the materials can easily be recollected using external magnets.In addition,according to the effects of different free radicals·O_(2)^(-),h^(+),and·OH on the photodegradation process,the photocatalysis mechanism of the MGTG was also thoroughly suggested.The antibacterial efficiency of the MGTG was also evaluated according to the inhibition of the Gram-positive bacteria strain Staphylococcus aureus(S.aureus).Concurrently,the antibacterial mechanism of the fabricated material was also proposed.These results confirm that the prepared material can be potentially employed in a wide range of applications,including wastewater treatment and antibacterial activity. | Tong Hoang Lin Che Quang Cong Nguyen Thanh Hoai Nam Hoang An Nguyen Duy Hai Ton That Buu Thoi Le Nhat Binh Hoang Le Minh Lam Thanh Ngan Hoang Thuy Kim Ngan Du Chi Vi Ta Dang Khoa Nguyen Huu Hieu | 2023 | Journal of Semiconductors2023，44，12： | 0 |
| 19 | Respect for Human Rights:a Fundamental Foundation for a World of Peace,Security and Harmony显示文摘Peace, security, harmonious development and human rights are closely related. Firstly, peace and security are premise and precondition for the insur-ance of human rights. It is obvious that when human beings continue to be threat-ening by wars, conflicts and chaos, their right to life is faint and insecure, and other human rights would not be fully respected or protected. On the other hand, peace and security are foundation for everyone to pursue his or her own objectives. In other words, in a society where peace and secu-rity are maitained, people will have oppor-tunity to enjoy their human rights and to affirm their own ego. | DANG DUNG CHI | 2007 | The Journal of Human Rights2007，6，1： | 0 |
| 20 | SPP1 and the risk score model to improve the survival prediction of patients with hepatocellular carcinoma based on multiple algorithms and back propagation neural networks显示文摘Hepatocellular carcinoma(HCC)is associated with poor prognosis and fluctuations in immune status.Although studies have found that secreted phosphoprotein 1(SPP1)is involved in HCC progression,its independent prognostic value and immune-mediated role remain unclear.Using The Cancer Genome Atlas and Gene Expression Omnibus data,we found that low expression of SPP1 is significantly associated with improved survival of HCC patients and that SPP1 expression is correlated with clinical characteristics.Univariate and multivariate Cox regression confirmed that SPP1 is an independent prognostic factor of HCC.Subsequently,we found that T cell CD4 memory-activated monocytes,M0 macrophages,and resting mast cells showed significant differences in penetration in the high and low SPP1 expression groups.Next,we used the Weighted Gene Co-Expression Network and Least Absolute Shrinkage Sum Selection Operator algorithms to construct a risk score for the 9-immune-related genes signature.The risk score showed a good ability to identify high and low-risk patients and improved survival prediction.We also used multivariate Cox regression to validate that risk score was significantly correlated with SPP1 and overall survival.Lastly,the Back-Propagation Neural Network confirmed the reliability of the results of multiple algorithms.In conclusion,the findings suggest that SPP1 is an independent marker of HCC survival and immunotherapy. | WENLI ZENG FENG LING KAINUO DANG QINGJIA CHI | 2023 | BIOCELL2023，47，3： | 0 |
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