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| 1 | Big data challenge: a data management perspective显示文摘 | Jinchuan CHEN Yueguo CHEN Xiaoyong DU Cuiping LI Jiaheng LU Suyun ZHAO Xuan ZHOU | 2013 | Frontiers of Computer Science2013，7，2： | 21 |
| 2 | The role of m6A modification in the biological functions and diseases显示文摘N6-methyladenosine(m6A)is the most prevalent,abundant and conserved internal cotranscriptional modification in eukaryotic RNAs,especially within higher eukaryotic cells.m6A modification is modified by the m6A methyltransferases,or writers,such as METTL3/14/16,RBM15/15B,ZC3H3,VIRMA,CBLL1,WTAP,and KIAA1429,and,removed by the demethylases,or erasers,including FTO and ALKBH5.It is recognized by m6A-binding proteins YTHDF1/2/3,YTHDC1/2 IGF2BP1/2/3 and HNRNPA2B1,also known as'readers'.Recent studies have shown that m6A RNA modification plays essential role in both physiological and pathological conditions,especially in the initiation and progression of different types of human cancers.In this review,we discuss how m6A RNA methylation influences both the physiological and pathological progressions of hematopoietic,central nervous and reproductive systems.We will mainly focus on recent progress in identifying the biological functions and the underlying molecular mechanisms of m6A RNA methylation,its regulators and downstream target genes,during cancer progression in above systems.We propose that m6A RNA methylation process offer potential targets for cancer therapy in the future. | Xiulin Jiang Baiyang Liu Zhi Nie Lincan Duan Qiuxia Xiong Zhixian Jin Cuiping Yang Yongbin Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 16 |
| 3 | Source rupture process of Lushan M_S7.0 earthquake, Sichuan,China and its tectonic implications显示文摘The source rupture process of the MS7.0 Lushan earthquake was here evaluated using 40 long-period P waveforms with even azimuth coverage of stations.Results reveal that the rupture process of the Lushan MS7.0 event to be simpler than that of the Wenchuan earthquake and also showed significant differences between the two rupture processes.The whole rupture process lasted 36 s and most of the moment was released within the first 13 s.The total released moment is 1.9×1019N m with MW=6.8.Rupture propagated upwards and bilaterally to both sides from the initial point,resulting in a large slip region of 40 km×30 km,with the maximum slip of 1.8 m,located above the initial point.No surface displacement was estimated around the epicenter,but displacement was observed about 20 km NE and SW directions of the epicenter.Both showed slips of less than 40 cm.The rupture suddenly stopped at 20 km NE of the initial point.This was consistent with the aftershock activity.This phenomenon indicates the existence of significant variation of the medium or tectonic structure,which may prevent the propagation of the rupture and aftershock activity.The earthquake risk of the left segment of Qianshan fault is worthy of attention. | ZHAO CuiPing ZHOU LianQing CHEN ZhangLi | 2013 | Chinese Science Bulletin2013，58，28： | 13 |
| 4 | Electrical stimulation of acupoint combinations against deep venous thrombosis in elderly bedridden patients after major surgery显示文摘OBJECTIVE:To compare the effects of electrical stimulation of different acupoint combinations among postoperative bedridden elderly patients on hemorheology and deep venous blood flow velocity and investigate the role of electrical stimulation against deep vein thrombosis(DVT).METHODS:From November 2010 to October 2011,a total of 160 elderly bedridden patients after major surgery were divided into the conventional care group,invigorating and promoting Qi group,blood-activating and damp-eliminating group,and acupoint-combination stimulation group.Whole blood viscosity,plasma viscosity,D-dimer levels,lower limb skin temperature,lower limb circumference,and flow velocities of the external iliac vein,femoral vein,popliteal vein,and deep calf veins in all patients were documented and compared among the four groups.RESULTS:Whole blood viscosity,plasma viscosity,D-dimer levels,and lower limb circumference were significantly reduced in the blood-activating and damp-eliminating group compared with the conventional care group(P<0.05) and were almost equal to those in the acupoint-combination stimulation group(P>0.05).Lower limb venous flow velocities were accelerated in the invigorating and promoting Qi group compared with the other groups,excluding the acupoint-combination stimulation group(P<0.05).CONCLUSION:Hemorheological indices in postoperative bedridden elderly patients were improved after combined electrical stimulation at Yinlingquan(SP 9) and Sanyinjiao(SP 6).Combined electrical stimulation at Zusanli(ST 36) and Taichong(LR 3),on the other hand,accelerated lower limb venous flow. | Lili Hou Cuiping Chen Lei Xu PeihaoYin Wen Peng | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 13 |
| 5 | Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2显示文摘发信号的刺猬(Hh ) 在种类从果蝇到哺乳动物在胚胎的开发和成年织物动态平衡起枢轴的作用。Hh 信号是由 Smoothened (Smo ) 的 transduced,与 G 蛋白质有关的 seven-transmembrane 蛋白质联合了受体。尽管有 Hh 在果蝇和哺乳动物由激活 Smo 的保存机制,哺乳动物的 Hh 信号怎么是从 Smo 的 transduced 到 Gli 抄写因素,糟糕被理解。这里,我们提供证据二睫的蛋白质, Evc 和 Evc2,为 Ellis 货车 Creveld 症候群负责的人的疾病基因的产品, Smo 下游地行动到 transduce Hh 信号。我们发现 Evc/Evc2 的损失不影响声音的导致刺猬的 Smo phosphorylation 和睫的本地化,但是阻碍 Hh 小径激活由 Smo 的组成地活跃的形式调停了。Evc/Evc2 为在 Sufu −/− 房间的组成的 Gli 活动是非必需的,建议支持 Gli 激活的 Sufu 在上游的那 Evc/Evc2 幕。而且,我们证明 Hh 刺激 Evc/Evc2 的绑定到取决于 Smo C 终端细胞内部的尾巴的 phosphorylation 的 Smo 并且绑定在 Kif3a −/− 被废除眼睫毛缺乏的房间。我们建议 Hh 由导致它的 phosphorylation 激活 Smo,它招募由在主要的睫反对 Sufu 激活 Gli 蛋白质的 Evc/Evc2。 | Cuiping Yang Wenlin Chen Yongbin Chen Jin Jiang | 2012 | Cell Research2012，22，11： | 8 |
| 6 | Cross-cultural adaption and psychometric properties of the Chinese version of the Diabetes Behavior Rating Scale: a pilot study显示文摘Self-care behavior plays a major role in diabetic management. However, in China, a satisfactory instrument has not yet been developed to evaluate the compliance of self-care behavior for young patients with type 1 diabetes mellitus(T1 DM). The Diabetes Behavior Rating Scale(DBRS) has a potential to be the first mature instrument. The purpose of this study is to cross-culturally adapt the DBRS, and preliminarily evaluate its psychometric properties. The instrument translation included translation, back translation and culture adaptation. Psychometric properties were assessed in a sample of 116 young patients with T1 DM adapting insulin injection therapy. The Chinese version of the DBRS was divided to four subscales. Cronbach's α for the total scale was 0.92. The mean inter-item and item-total correlations were 0.35 and 0.54 respectively. Test-retest reliability showed good temporal stability(r=0.81, P=0.001). Negative correlations were found between DBRS scores with the Diabetes Distress Scale scores(r=.0.32, P=0.003) and hemoglobin A1 c(HbA1 c) levels(r=.0.36, P=0.002). Higher DBRS scores correlated with better glycemic control. The Chinese insulin injection therapy version of the DBRS is well translated and culturally adapted. It shows good overall reliability and validity and appears to be a valuable tool for assessing the diabetic self-care behaviors for young patients with T1 DM. | Jing Zhu Jingjing Xu Yang Chen Yong Gu Li Ji Yufeng Zhou Min Zhu Hsiang-Ting Hsu Xiaoping Huang Cuiping Yuan Yun Shi Dan Yan Lili Xie Shuang Chen Tao Yang Wei He | 2018 | Science China(Life Sciences)2018，61，3： | 6 |
| 7 | Expression and intercellular trafficking of the VP22 protein of CVI988/Rispens vaccine strain of Marek’s disease virus显示文摘The viral protein 22 (VP22) in the tegument of Marek’s disease virus serotype 1 (MDV-1) plays an im-portant role in cell-to-cell spread and viral propagation. Antiserum against the carboxyl terminus of VP22 was prepared by immunizing mice with recombinant VP22 expressed in E. coli, and used to in-vestigate its expression in chicken embryo fibroblast (CEF) cells infected with different MDV-1 strains. At an infection dose of PFU=50, intercellular trafficking of the VP22 into the nuclei of the surrounding receipt cells was detected as early as 3 hours post infection. By 6 hours after infection (before viral plague formation), the protein was detected in the whole nuclei of the recipient cells with no difference among MDV-1 strains CVI988/Rispens, GA and RB1B. Intra-nuclear accumulation of the VP22 protein was further increased when the viral plagues started to form. These results indicate that, albeit the ex-istence of the 201TKSERT206 deletion, the VP22 of the CVI988/Rispens vaccine strain has also intercel-lular-trafficking function, which might serve as a potential alternative delivering protein instead of virulent strains VP22. | CHEN HongJun, SONG CuiPing, QIN AiJian & ZHANG ChenFei Key Lab of Jiangsu Preventive Veterinary Medicine, Yangzhou University, Yangzhou 225009, China | 2007 | Science China(Life Sciences)2007，50，1： | 6 |
| 8 | Rupture process of the Wenchuan M8.0 earthquake of Sichuan, China: the segmentation feature显示文摘Moment tensor solution, rupture process and rupture characteristics of the great Wenchuan M8.0 earthquake are studied by using 39 long-period P and SH waveforms with evenly azimuth coverage of stations. Our results reveal that the Wenchuan M8.0 event consisted of 5 sub-events of Mw≥7.3 occurring succesively in time and space. Rupture started with a Mw7.3 introductory strike-slip faulting in the first 12 s, then within 12?40 s, two sub-events with Mw7.6 and Mw7.4 occurred within 80 km northeast from the initial point with the dominant rupture type of thrust moving. From 40 to 62 s, a Mw7.5 and Mw7.4 right-lateral strike-slip type of sub-events occurred on the two sides of Beichuan, 120 km away northeast from the initial point. The whole rupture process lasted 105 s and unilaterally propagated from the initial point on the WS section of the Yingxiu-Beichuan fault to the NE direction, resulting in a 230-km-long surface rupture zone and the average surface dislocation is up to 4 m. Two asperities are identified and the whole rupture process is formed by WS and NE parts. In the WS part named Dujiangyang-Wenchuan, where the initial point is located, the rupture process showed reverse faulting with the maximum slip of 8.2 m. Around Mianzhu, rupture changed to right-lateral strike slip faulting and formed a Beichuan-Qingchuan large slip area. The rupture area on this part is about 10 km in depth, shallower than on the WS part. The maximum slip is 6.53 m. Consequently, there formed 2 segments with the surface dislocation larger than 6 m. One is the Dujiangyan-Wenchuan segment with the maximum surface displacement of 6.44 m, the other is the Beichuan-Qingchuan segment with the maximum surface displacement of 6.53 m. This segmentation may have its geological and tectonic background. | ZHAO CuiPing CHEN ZhangLi ZHOU LianQing LI ZhiXiong KANG yin | 2010 | Chinese Science Bulletin2010，55，3： | 5 |
| 9 | Marek's disease virus VP22 enhances potentially the immune response of E SAT-6/CFP-10 against Mycobacterium bovis infection显示文摘对 Mycobacterium bovis 的当前可得到的疫苗,肺结核的原因的代理人,别提供可靠功效,因此对有改进功效的一支新奇疫苗有需要。这里,我们使用蛋白质 transduction 技术交付直接表示 mycobacterial 抗原指向房间的 DNA 疫苗。我们使用了包括 VP22 的领域(PTD ) 蛋白质从 Marek 的疾病病毒 serotype 结合的各种各样的蛋白质 transduction 1 (MDV-1 ) ,作为为编码抗原的 DNA 构造的交货系统,早能分泌的 antigenic target-6 kDa (ESAT-6 ) 蛋白质和文化过滤蛋白质 10 (CFP-10 ) M。bovis。真核细胞的表示 plasmid pZ106,编码抗原 ESAT-6 和 CFP-10,结合了到各种各样的 PTD,被用来构造试验性的准备。我们的调查结果与 CFP-10 独自或在联合表明了那 VP22 : ESAT-6 熔化蛋白质能传播进包围 transfected 房间的房间单层的所有原子核。而激活 trans transcriptional PTD 出现了,熔化蛋白质和 8R 肽的有限交货是不能的交付熔化蛋白质进任何 untransfected 房间。我们证明了有熔化到 VP22 的准备的那免疫导致更高的抗体和干扰素 -- titer (P < 0.05 ) 。一起拿,我们的结果证明 MDV-1 VP22 用 DNA 疫苗在基因治疗和免疫用作潜在的有免疫力的 enhancer,为 M 的预防提供一条新奇途径。bovis 感染。 | Hongjun Chen Wei Wang Cuiping Song Shengqing Yu Chan Ding | 2010 | Acta Biochimica et Biophysica Sinica2010，42，5： | 4 |
| 10 | The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR显示文摘On January 22,2020,China National Center for Bioinformation(CNCB)released the 2019 Novel Coronavirus Resource(2019nCoVR),an open-access information resource for the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).2019nCoVR features a comprehensive integration of sequence and clinical information for all publicly available SARS-CoV-2 isolates,which are manually curated with value-added annotations and quality evaluated by an automated in-house pipeline.Of particular note,2019nCoVR offers systematic analyses to generate a dynamic landscape of SARS-CoV-2 genomic variations at a global scale.It provides all identified variants and their detailed statistics for each virus isolate,and congregates the quality score,functional annotation,and population frequency for each variant.Spatiotemporal change for each variant can be visualized and historical viral haplotype network maps for the course of the outbreak are also generated based on all complete and high-quality genomes available.Moreover,2019nCoVR provides a full collection of SARS-CoV-2 relevant literature on the coronavirus disease 2019(COVID-19),including published papers from PubMed as well as preprints from services such as bioRxiv and medRxiv through Europe PMC.Furthermore,by linking with relevant databases in CNCB,2019nCoVR offers data submission services for raw sequence reads and assembled genomes,and data sharing with NCBI.Collectively,SARS-CoV-2 is updated daily to collect the latest information on genome sequences,variants,haplotypes,and literature for a timely reflection,making 2019nCoVR a valuable resource for the global research community.2019nCoVR is accessible at https://bigd.big.ac.cn/ncov/. | Shuhui Song Lina Ma Dong Zou Dongmei Tian Cuiping Li Junwei Zhu Meili Chen Anke Wang Yingke Ma Mengwei Li Xufei Teng Ying Cui Guangya Duan Mochen Zhang Tong Jin Chengmin Shi Zhenglin Du Yadong Zhang Chuandong Liu Rujiao Li Jingyao Zeng Lili Hao Shuai Jiang Hua Chen Dali Han Jingfa Xiao Zhang Zhang Wenming Zhao Yongbiao Xue Yiming Bao | 2020 | Genomics, Proteomics & Bioinformatics2020，18，6： | 4 |
| 11 | An effective scheme for top-k frequent itemset mining under differential privacy conditions显示文摘Dear editor,Frequent itemset mining(FIM)is important in many data mining applications[1],such as web log mining and trend analysis.However,if the data are sensitive(e.g.,web browsing history),directly releasing frequent itemsets and their support may breach user privacy.The protection of user privacy while obtaining statistical information is important. | Wenjuan LIANG Hong CHEN Jing ZHANG Dan ZHAO Cuiping LI | 2020 | Science China(Information Sciences)2020，63，5： | 3 |
| 12 | Optimized prime editing efficiently generates glyphosate-resistant rice plants carrying homozygous TAP-IVS mutation in EPSPS显示文摘Dear Editor,Prime editing is a novel and universal CRISPR-Cas-derived precise genome-editing technology and has great potentials for applications in basic plant research and crop molecular breeding(Anzalone et al.,2019).Although low efficiency has restrained the original prime editors(PEs)from being used as a routine tool for precise genome editing in plants,an iterative update of the PEs is removing this obstacle(Lin et al.,2021;Xu et al.,2022).Recently,the Liu group reported three optimization strategies for improving prime editing efficiency(Chen et al.,2021;Nelson et al.,2022).The first strategy is based on engineered prime editing guide RNAs(epegRNAs),which were generated by incorporating structured RNA motifs to the 3′terminus of pegRNAs.This strategy enhances pegRNA stability and prevents degradation of the 3′extension(Nelson et al.,2022).The second strategy is based on the optimized PE2 protein(PEmax),which harbors a SpCas9 variant with increased nuclease activity,an additional nuclear localization signal(NLS)sequences,and a new linker between nCas9 and reverse transcriptase(Chen et al.,2021).The third strategy is based on inhibition of DNA mismatch repair(MMR)in cells(Chen et al.,2021).In this work,we tested the optimized PEs generated with these three strategies in rice,demonstrating that the optimized PEs greatly improved prime editing efficiency in rice.We named the two optimized PEs ePE3max and ePE5max:the former is comprised of the PEmax protein,an epegRNA with evopreQ1 appended to its 3′end,and a nicking sgRNA;the latter is comprised of the ePE3max system and a dominant negative OsMLH1 variant for inhibiting MMR.Using the two optimized PEs,we efficiently generated homozygous and heterozygous T173I,A174V,and P177S(TAP-IVS)mutation in EPSPS in rice,which lays a solid foundation for rice non-transgenic glyphosate-resistance breeding. | Yuanyuan Jiang Yiping Chai Dexin Qiao Junya Wang Cuiping Xin Wei Sun Zhenghong Cao Yu Zhang Yun Zhou Xue-Chen Wang Qi-Jun Chen | 2022 | Molecular Plant2022，15，11： | 3 |
| 13 | Object-Based Classification Method for PolSAR Images with Improved Scattering Powers and Contextual Features显示文摘This paper proposes a new object-based classification method for Polarimetric synthetic aperture radar(Pol SAR) images, which considers scattering powers from an improved model-based polarimetric decomposition approach, as well as the spatial and textural features. With the decomposition, the scattering ambiguities between oriented buildings and vegetation are reduced. Furthermore,various contextual features are extracted from the object and incorporated into the K-nearest neighbors(k-NN)based classification. To reduce the feature redundancy, a new Supervised locally linear embedding(S-LLE) dimensionality reduction method is introduced to map the high dimensional polarimetric signatures into the most compact low-dimensional structure for classification. Experimental results with Airborne synthetic aperture rada(AIRSAR)C-band Pol SAR image demonstrate the superior performance to other methods. | YUAN Zhengwu CHEN Ran CHEN Cuiping LUO Xiaobo LIU Minghao | 2017 | Chinese Journal of Electronics2017，26，4： | 2 |
| 14 | Biocompatible, small-sized and well-dispersed gold nanoparticles regulated by silk fibroin fiber from Bombyx mori cocoons显示文摘Biocompatible, small-sized but well-dispersed gold nanoparticles (Au NPs) remain a major challenge for their synthesis. Here a convenient solution impregnation technique is developed to prepare such Au NPs under the regulation of degummed silk fibroin fibers (SFFs) extracted from Bombyx mori cocoons. SFFs play multiple roles in the formation of Au NPs such as reactive substrate to capture AuCl4^- ions by the chelation of -C = 0, reducing agent for Au(0) by the reduction of -OH , and modifiers to render biocompatible Au NPs by some functional groups and biomolecules. The as-prepared Au NPs with a size of 7-10 nm are embedded in the solid SFF substrate, and can disperse well in the liquid system by the disintegration of SFFs into silk fibroin (SF) in a certain CaCl2 solution. The biocompatible Au NPs exhibit uniform small size and distribute stably in both solid and solution states, which have distinctive properties and functional advantages, and bring great convenience to their storage and transportation. | Chengzhi YANG Shikun CHEN Huilan SU Haoyue ZHANG Jianfei TANG Cuiping GUO Fang SONG Wang ZHANG Jiajun GU Qinglei LIU | 2019 | Frontiers of Materials Science2019，13，2： | 2 |
| 15 | Phase Boundary Mapping in ZrNiSn Half-Heusler for Enhanced Thermoelectric Performance显示文摘The solubility range of interstitial Ni in the ZrNi1+xSn half-Heusler phase is a controversial issue,but it has an impact on the thermoelectric properties.In this study,two isothermal section phase diagrams of the Zr-Ni-Sn ternary system at 973K and 1173 K were experimentally constructed based on the binary phase diagrams of Zr-Ni,Zr-Sn,and Ni-Sn.The thermodynamic equilibrium phases were obtained after a long time of heating treatment on the raw alloys prepared by levitation melting.Solubilities of x<0:07 at 973 K and x<0:13 at 1173 K were clearly indicated.An intermediate-Heusler phase with a partly filled Ni void was observed,which is believed to be beneficial to the lowered lattice thermal conductivity.The highest ZT value~0:71 at 973 K was obtained for ZrNi_(1.11)Sn_(1.04).The phase boundary mapping provides an important instruction for the further optimization of ZrNiSn-based materials and other systems. | Xiaofang Li Pengbo Yang Yumei Wang Zongwei Zhang Dandan Qin Wenhua Xue Chen Chen Yifang Huang Xiaodong Xie Xinyu Wang Mujin Yang Cuiping Wang Feng Cao Jiehe Sui Xingjun Liu Qian Zhang | 2020 | Research2020，，1： | 2 |
| 16 | Thermodynamic database of the phase diagrams in the Mg-Al-Zn-Y-Ce system显示文摘The Mg-Al-Zn-Y-Ce system is one of the key systems for designing high-strength Mg alloys. The purpose of the present article is to develop a thermodynamic database for the Mg-Al-Zn-Y-Ce multicomponent system to design Mg alloys using the calculation of phase diagrams (CALPHAD) method, where the Gibbs energies of solution phases such as liquid, fcc, bcc, and hcp phases were described by the subregular solution model, whereas those of all the compounds were de- scribed by the sublattice model. The thermodynamic parameters describing Gibbs energies of the different phases in this database were evaluated by fitting the experimental data for phase equilibria and thermodynamic properties. On the basis of this database, a lot of information concerning stable and metastable phase equilibria of isothermal and vertical sections, mo- lar fractions of constituent phases, the liquidus projection, etc., can be predicted. This database is expected to play an im- portant role in the design of Mg alloys. | LIU Xingjun WANG Cuiping WEN Mingzhong CHEN Xing PAN Fusheng | 2006 | Rare Metals2006，25，5： | 2 |
| 17 | Tidal Asymmetry Changes in a Shallow Mud Estuary by a Restoration Project显示文摘The tidal asymmetry-induced siltation below tidal barriers is a worldwide problem that restricts regional socio-economic and environmental development. The hydrodynamic processes of the small mud estuary also feature a high uncertainty after estuary restoration measures. In this study, a hydrodynamic model based on the MIKE21 is used to quantify the responses of tidal asymmetry to a two-phase restoration project in Shuanglong Estuary, Bohai Bay, China. According to the numerical modeling results, the tidal flat removal in the upper estuary(first-phase restoration) induces the flood asymmetry switching to the ebb asymmetry in unrestored reach but enhances flood asymmetry in widening restored reach. Although the tidal asymmetry reverts to flood-dominated pattern after full restoration over the estuary, the imbalance between flood and ebb velocities is relieved. A possible net sediment transport pattern based on a comparison of dominant asymmetric current and actual sediment transport period shows net sediments in the upper estuary and inlet transport seaward and landward, respectively, in the first-phase restoration, whereas landward net sediment transport occurs in the whole estuary under the second-phase restoration scenario. Given these results, we assume that a switch from the flood-dominated estuary to ebb-dominated estuary can be caused by redesigning the cross-sectional profile. The quantitative comparison of Lagrangian residual currents also implies that a channel–shoal structure rather than a flat bathymetry can promote the mass transport. Therefore, reshaping the channel–tidal flat system in restoration projects can prevent the sedimentation of the estuary and improve the water environment. | LIANG Huidi KUANG Cuiping GU Jie MA Yue CHEN Kuo LIU Xu | 2019 | Journal of Ocean University of China2019，18，2： | 2 |
| 18 | The Role of Ti in the Preparation of SiC/7075 Aluminum Matrix Composite显示文摘SiC/7075 aluminum matrix composites were prepared by a liquid stirring method.The role of Ti facilitating the preparation of SiC/7075 aluminum matrix were studied by means of direct-reading spectrometer,scanning electron microscope,energy dispersive spectrometer,X-ray diffraction and the sessile drop method.The results show that the SiC content in the SiC/7075 composite increases with an increase of Ti addition.The addition of Ti can significantly improve the wettability of SiC/Al system,there is a critical value of above 0.5%of Ti content in improving the wettability of the Al/SiC system at 1173K.The temperature of the'non wetting-wetting'transition for the(Al-2Ti)/SiC system is about 1123K,the contact angle decreases to 88°at 200 seconds and reaches a stable contact angle of 28°at 2100 seconds. | ZHANG Wenda CHEN Chengcheng XU Hong CHE Luchang GUO Cuiping DU Zhenmin | 2020 | Journal of Wuhan University of Technology(Materials Science)2020，35，2： | 2 |
| 19 | Water quality assessment by pollution-index method in the coastal waters of Hebei Province in western Bohai Sea, China显示文摘 | Shuguang Liu Sha Lou Cuiping Kuang Wenrui Huang Wujun Chen Jianle Zhang Guihui Zhong | 2011 | Marine Pollution Bulletin2011，，10： | 2 |
| 20 | Comparative analysis and evolutionary significance of the HMG1 gene in crucian carp,blunt snout bream,and their polyploid progeny显示文摘高活动性组蛋白质的全身的 mRNA 1 个编码基因(HMG1 ) 被 RACE-PCR 从红鲫鱼鲤鱼(Carassius auratus 红 var ) 获得,钝猪嘴鲷(Megalobrama amblycephala ) ,并且他们的三倍性并且 tetraploid 子孙。顺序包含了为 193 氨基酸编码的 579 核苷酸的一个开的读物框架。HMG1 的核苷酸身份比在 tetraploid 混血儿和父亲的钝猪嘴鲷(97%) 之间在 tetraploid 混血儿和母亲的红鲫鱼鲤鱼(99%) 之间是更高的。在三倍性的混血儿和每个父母(95%) 之间的核苷酸身份在父母(98%) 之间是比那低的。在 tetraploid 混血儿和每个父母(100%) 之间的蛋白质身份在三倍性的混血儿和每个父母(97%) 之间比那高。我们的结果建议种间的杂交在三倍性的混血儿产生震动到 HMG1 基因,引起核苷酸的分叉。tetraploid 混血儿的 HMG1 蛋白质与它的父母的一致,它减少了在等位基因之间的生气不兼容的障碍,提供形成在自然的新多倍体种的两性的肥沃的 tetraploid 混血儿的基础。HMG1 蛋白质的第二等、第三级的结构包含八他 lices,三个开关,在 N 终点的二个 DNA 有约束力的领域,和在 C 终点的一条长酸的尾巴。一起,这些数据建议 HMG1 蛋白质起蛋白质 DNA 相互作用的一个作用,在原子核便于各种各样的 DNA 依赖的活动。我们也调查了鱼,两栖动物,爬虫,鸟,和哺乳动物的 HMG1 蛋白质的发展史。我们的结果建议 HMG1 是高度被保存了的祖先的蛋白质。这些数据提供种间的杂交怎么可以形成多倍体混血儿的线索。 | Dong Liu Zhen Liu Shaojun Liu Liangguo Liu Cuiping You Lin Chen Huan Zhong Yun Liu | 2009 | Progress in Natural Science:Materials International2009，19，12： | 1 |
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