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| 1 | Surface latent heat flux anomalies prior to the Indonesia Mw9.0 ear thquakeof 2004显示文摘The temporal and spatial variations of surface latent heat flux (SLHF) before and after the Mw9.0 earthquake that occurred on the west coast of Sumatra, Indonesia on 26 December 2004 are summarized. It is found that before the earthquake significant SLHF anomalies occurred at the epicentral area and its vicinity. The largest SLHF anomaly oc- curred on the subduction zone in the middle part of Burma micro-plate, where the middle part of the rup- ture zone is located and the aftershocks are concen- trated. The developments of the anomaly involved growing of the anomaly from small to large and spreading of the anomaly from disordered to con- centrated. The anomaly began to occur on the east extensional boundary of the Burma micro-plate and its adjacent oceanic basin, and then propagated to the west compressive boundary, where the subduc- tion zone exists. Finally, the anomaly disappeared after the main shock. The seismic source is consid- ered to be a dissipation system. The increase of stress prior to an earthquake may enhance the ex- change of energy and material between the seismic source system and the outer system, resulting in the increase of the rate of energy exchange between sea surface and atmosphere, which is believed to be the main reason of the generation of SLHF anomaly. | CHEN Meihua DENG Zhihui YANG Zhuzhuan MA Xiaojing | 2006 | Chinese Science Bulletin2006，51，8： | 14 |
| 2 | Self-organized ordering of earthquakes(M≥8) in China's Mainland显示文摘纸论述了大地震的一个新常规模式(网络结构) 在过去的 700 年期间发生在大陆中国,它可能是有用的改进大地震的理解并且能为未来伟人地震的预言的学习用作一个库。因为有在在中国的宽程度的历史、最近的地震的相当完全、充满信心的记录,它能被做。 | Xu Daoyi Men Kepei Deng Zhihui | 2010 | Engineering Sciences2010，8，4： | 10 |
| 3 | Palladium-Catalyzed Asymmetric [4+3]-Cyclization Reaction of Fused 1-Azadienes with Amino-trimethylenemethanes: Highly Stereoselective Construction of Chiral Fused Azepines显示文摘Summary of main observation and conclusion A Pd-catalyzed asymmetric aromative[4+3]-cyclization reaction of amino-trimethylenemethanes(TMM,1d,ip3-oles)with fused 1-azadienes has been developed.This method enables access to the synthetically importance and biologically active benzofuran fused azepines and indeno-azepines in excellent efficiency and stereoselectivity(up to 95%yield,99%ee,>19:1 dr). | Prathibha Kumari Weiwei Liu Cheng-Jie Wang Jun Dai Mei-Xin Wang Qi-Qiong Yang Yu-Hua Deng Zhihui Shao | 2020 | Chinese Journal of Chemistry2020，38，2： | 5 |
| 4 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 5 | Complicated phenomena of the Beichuan-Yingxiu surface fracture zone during Wenchuan Ms8.0 earthquake in Sichuan Province,China显示文摘After Wenchuan Ms8.0 earthquake,the surface fractures have been investigated in Beichuan City and Yingxiu Town.It was found that the Beichuan-Yingxiu earthquake fracture zone trends northeastward,dipping to northwest.The earthquake fracture zone is mainly characterized by thrust faulting with small amounts of strike-slip movement,and demonstrating various complexities for different areas.The phenomena related to dextral strike-slip displacement are found in Beichuan City and those related to left-lateral strike-slip movement in Yingxiu Town.The compressive shortening of the two surface fracture zones in Beichuan City is 2.8―3.9 m and the left-lateral strike-slip displacement of the surface fractures in Yingxiu Town is 0.52 m. | DENG ZhiHui YANG ZhuEn SUN ZhaoMin CHEN GuiHua MA WenTao SUN Qian | 2008 | Chinese Science Bulletin2008，53，24： | 4 |
| 6 | Three new lignan glucosides from the roots of Scutellaria baicalensis显示文摘Three new lignan glucosides, baicalensinosides A–C(1–3), were isolated from the roots of Scutellaria baicalensis. The structural elucidation was achieved by in-depth spectroscopic examinations and qualitative chemical test. Structurally, these compounds belong to the 3,4-dibenzyltetrahydrofurantype lignan glycoside with a mono-hydroxyl substitution at the 70-position of benzylidene group on the numbering system of lignans being one of their shared critical features. The anti-osteoporotic activity of the isolated compounds was assessed in an in vitro osteoprotegerin(OPG) transcriptional activity assay using dual luciferase reporter detection. At 10 μmol/L, compounds 1–3 increased the relative activating ratio of OPG transcription to 1.83, 0.84 and 0.98 times that of the control group, respectively. | Hailin Long Haijing Zhang Anjun Deng Lin Ma Lianqiu Wu Zhihong Li Zhihui Zhang Wenjie Wang Jiandong Jiang Hailin Qin | 2016 | Acta Pharmaceutica Sinica B2016，6，3： | 2 |
| 7 | Peptide-specific,allogeneic T cell response in vitro induced by a self-peptide binding to HLA-A2显示文摘The role of the bound peptide in alloreactive T-cell recognition is controversial, ranging from pep-tide-independent to peptide-specific recognition of alloreactive T-cells. The aim of this study is to find the evidence that there exist peptide/MHC complex (pMHC)-specific CTLs among alloreactive T cells generated with long-term mixed lymphocytes culture (LTMLC). A single pMHC was manipulated by loading the TAP-defective, HLA-A2 expressing T2 cells with a viral peptide (LMP2A426-434) or a self-peptide (Tyr369-377). The PBLs samples from 4 HLA-A2 positive (HLA-A2+ve) and 4 HLA-A2 negative (HLA-A2-ve) donors were included in this study. The HLA-A2+ve PBL co-cultured with the LMP2A426-434 pulsed T2 (T2/LMP) stands for the nominal T-cell response to a viral antigen, and the HLA-A2-ve PBLs co-cultured with the Tyr369-377 pulsed T2 (T2/Tyr) for alloreactive T-cell response to an allogeneic antigen. The specificity of the expanded CTLs after the LTMLC was detected by their specific cytotoxicity and binding ability to specific pMHC-tetramer. An HLA-A2 restricted, HIV peptide (Gag77-85)was included for control. The cultural bulk of HLA-A2+ve PBLs with the T2/LMP showed an elevated specific cytotoxicity against the T2/LMP compared to that against the T2/HIV (26.52%±3.72% vs 7.01%±0.87%, P<0.001), and an increased frequency of binding to LMP-tetramer compared to that binding to HIV-tetramer (0.98%±0.33% vs 0.05%±0.01%, P=0.0014). The cultural bulk of HLA-A2-ve PBLs with the T2/Tyr showed a more active cytotoxicity against the T2/Tyr than that against T2/HIV (28.07%±2.58% vs 6.87%±0.01 %, P<0.001), and a higher frequency of binding to the Tyr-tetramer than that binding to the HIV-tetramer (0.88%±0.3% vs 0.06%±0.03%, P=0.0018). Our results indicate that the LTMLC is able to expand the viral antigen-specific CTLs as well as allogeneic antigen-specific CTLs. A relatively large proportion of alloreactive CTLs should be pMHC-specific, i.e., the specificity of the alloreactive lines depends on both the bound peptide and the allotype of MHC. Our observations support the hypothesis that the cumulative effect of T cells specific to each peptide epitope could account for the strength and diversity of the alloresponse. The method using manipulated pMHC and the LTMLC to generate pMHC-specific, alloreactive CTLs is of potential importance for adoptive T-cell immunotherapy. | WENG XiuFang, LIANG ZhiHui, LU XiaoLing, ZHONG MaoHua, LU ShengJun, ZHANG CaiE, DENG Jing, WU XiongWen & GONG FeiLi Department of Immunology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China | 2007 | Science China(Life Sciences)2007，50，2： | 2 |
| 8 | Preliminary Study on the Dynamic Variations of the Surface Thermal Flux before and after the M_S5.7 Earthquake of 2005 in Jiujiang City,Jiangxi Province显示文摘The temporal and spatial variations of surface latent heat flux(SLHF)and diagnostic air temperature at 2m before and after the M_S5.7 earthquake occurring on November 26,2005 in the area between Ruichang City and Jiujiang City,Jiangxi Province are summarized in this paper.It is found that before the earthquake significant SLHF anomalies and air temperature anomalies occurred in the epicentral area and its vicinity.The air temperature anomalies appeared from the 2nd to the 13th of November,2005 and were concentrated at the epicentral area and in its southern part.Then two days later,that is,from the 4th to the 15th of November 2005,significant SLHF anomalies occurred in the epicentral area and to its northern area where many lakes are distributed along the active faults.During the anomalous period,the SLHF and air temperature at 2m exceeded the sum of average daily value over 26 years and 1.5 times of its mean square deviation.Both anomalies had maintained for 12 days with a peculiar distribution related to the tectonic active zone.It is considered that both of air temperature anomalies and SLHF anomalies are correlated to the movement of thermal flux from underground prior to earthquake.SLHF anomalies occurred over wide regions covered with abundant water,whereas air temperature anomalies occurred over land. | Chen Meihua Deng Zhihui Wang Yu Liao Zhihui Zu Jinhua | 2008 | Earthquake Research in China2008，22，2： | 1 |
| 9 | Numerical study on the gas-kinetic high-order schemes for solving Boltzmann model equation显示文摘The high-order compact finite difference technique is introduced to solve the Boltzmann model equation, and the gas-kinetic high-order schemes are developed to simulate the different kinetic model equations such as the BGK model, the Shakhov model and the Ellipsoidal Statistical (ES) model in this paper. The methods are tested for the one-dimensional unsteady shock-tube problems with various Knudsen numbers, the inner flows of normal shock wave for different Mach numbers, and the two-dimensional flows past a circular cylinder and a NACA 002 airfoil to verify the reliability of the present high-order algorithm and simulate gas transport phenomena covering various flow regimes. The computed results are found in good agreement both with the theoretical prediction from continuum to rarefied gas dynamics, the related DSMC solutions, and with the experimental results. The numerical effect of the schemes with the different precision and the different types of Boltzmann collision models on the computational efficiency and computed results is investigated and analyzed. The numerical experience indicates that an approach developing and applying the gas-kinetic high-order algorithm is feasible for directly solving the Boltzmann model equation. | LI ZhiHui PENG AoPing ZHANG HanXin DENG XiaoGang | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，9： | 1 |
| 10 | Impact vibration reduction for flexible manipulators via controllable local degrees of freedom显示文摘When performing operation tasks,the interaction between a flexible manipulator and a grasped object usually results in an impact.In this paper,a new way is suggested to alleviate impact vibration of a flexible manipulator via its structural characteristic when capturing a moving object.Controllable local degrees of freedom are introduced to the topological structure of the flexible manipulator,and used as an effective tool to combat impact vibration through dynamic coupling.A corresponding method is put forward to reduce impact vibration responses of the flexible manipulator via the controllable local degrees of freedom.By planning motion of the controllable local degrees of freedom,appropriate control force can be constructed to increase the modal damping and stiffness and eliminate the exciting force simultaneously,thereby reducing impact vibration responses of the flexible manipulator.Simulations are conducted and results are shown to prove the presented method. | Bian Yushu Gao Zhihui Deng Yuchun | 2013 | Chinese Journal of Aeronautics2013，26，5： | 1 |
| 11 | Preliminary study on co-seismic step changes of Tachai well water level, Simao, Yunnan Province 显示文摘 | Yang Zhuzhuan Deng Zhihui Zhao Yunxu | 2005 | Acta Seismologica Sinica2005，27，56： | 1 |
| 12 | An approach to evaluating the network security in triangular fuzzy environment显示文摘 | Yan Zhihui Liu Zhigang Deng Gengsheng | 2012 | International Journal of Digital Content Technology and its Applications2012，6，19： | 1 |
| 13 | Development and characterization of intron-flanking EST-PCR markers in Hevea bra- siliensis 显示文摘 | LI Dejun XIA Zhihui DENG Zhi | 2011 | Molecular Biotechnology2011，51，2： | 1 |
| 14 | The impact of COVID-19 on China’s regional economies and industries显示文摘Scientifically assessing the economic impact of major public health emergencies,containing their negative effects,and enhancing the resilience of an economy are important national strategic needs.The new coronavirus disease(COVID-19)has,to date,been effectively contained in China,but the threat of imported cases and local risks still exist.The systematic identification of the virus’s path of influence and intensity is significant for economic recovery.This study is based on a refined multi-regional general equilibrium analysis model,which measures the economic and industrial impacts at different epidemic risk levels in China and simulates development trends and the degree of damage to industries and the economy under changes to supplies of production materials and product demand.The results show that,at the macroeconomic level,China’s GDP will decline about 0.4%to 0.8%compared to normal in 2020,with an average drop of about 2%in short-term consumption,an average drop in employment of about 0.7%,and an average increase in prices of about 0.9%.At the industry level,the epidemic will have the greatest short-term impact on consumer and laborintensive industries.For example,the output value of the service industry will fall 6.3%compared to normal.Looking at the impact of the epidemic on the industrial system,the province most affected by the epidemic is Hubei,which is the only province in China in the level-1 risk category.As the disease spread outward from Hubei,there were clear differences in the main industries that were impacted in different regions.In addition,simulation results of recovery intensity of regional economies under the two epidemic response scenarios of resumption of work and production and active fiscal stimulus policies show that an increase in fiscal stimulus policies produces a 0.3%higher rate of gross regional product growth but it causes commodity prices to rise by about 1.8%.Measures to resume work and production offer a wider scope for industrial recovery. | WU Feng LIU Guijun GUO Naliang LI Zhihui DENG Xiangzheng | 2021 | Journal of Geographical Sciences2021，31，4： | 1 |
| 15 | Purification and characterization of a novel fibrinolytic enzyme from the polychaete,Neanthes japonica (lznka)显示文摘 | Deng Zhihui Wang Shaohua Li Qi | 2010 | Bioresource Technology2010，31，6： | 1 |
| 16 | A new method for the detection of ATP using a quantum-dot-tagged aptamer显示文摘 | Zhang Chen Guang Li Lan Zhang Junfeng Jiang Zhao Li Zhihui Peng Le Deng | 2008 | Analytical and Bioanalytical Chemistry2008，，6： | 1 |
| 17 | Multichannel InSAR DEM Reconstruction through Improved Closed form Robust Chinese Remainder Theorem显示文摘 | YUAN Zhihui DENG Yunkai LI Fei | 2013 | IEEE Geo science and Remote Sensing Letters2013，10，6： | 1 |
| 18 | Bioleaching mechanism of heavy metals in the mixture of contaminated soil and slag by using indigenous Penicillium chrysogenum strain F1显示文摘 | Xinhui Deng Liyuan Chai Zhihui Yang Chongjian Tang Yangyang Wang Yan Shi | 2013 | Journal of Hazardous Materials2013，，： | 1 |
| 19 | Bioleaching mechanism of heavy metals in the mixture of contaminated soil and slag by using indigenous Penicillium chrysogenum strain F1 显示文摘 | DENG Xinhui CHAI Liyuan YANG Zhihui | 2013 | Journal of Hazardous Materials2013，，1： | 1 |
| 20 | Development and Validation of a HPLC Method for Determination of Flavone Glycoside-Camellianin B in Cephalotaxus Sinensis显示文摘A simple,rapid and sensitive method for the quantification of camellianin B in Cephalotaxus sinensis(C.sinensis)a natural plant with anti-hyperglycemic effect,was developed and validated by reversed phase liquid chromatography.Chromatographic separation was achieved on a C18 column and an isocratic elution was carried out at a flow-rate of 1.0 mL·min^(-1) with the acetonitrile-water containing0.1%formic acid(19∶81,v/v).The detection wavelength was set at 330 nm.The calibration curve was linear over the concentration range of 0.25-50μg·mL^(-1) with correlation coefficients larger than0.999 5.The limit of detection and limit of quantification were 0.09μg·mL^(-1)and 0.25μg·mL^(-1),respectively.The precisions and accuracy for all samples were acceptable.The validated method has been successfully applied for the quantification of camellianin B in C.sinensis harvested in different months and may also be used as the quality evaluation of this herb medicine. | Yongqian Zhang Zhihui Xu Chao Wei Yan Chen Yulin Deng | 2017 | Journal of Beijing Institute of Technology2017，26，1： | 1 |
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