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| 1 | A Versatile Crosslinking Strategy on Facile Fabrication of Fluorescent Hydrogels via o-Phthalaldehyde Ternary Condensation显示文摘It is of great sighificance to develop rapid crosslinking strategies to enrich the functions of hydrogels and simplify the preparation process of hydrogels.Herein,we applied the ternary condensation reaction of o-phthalaldehyde(OPA)with thiol and amino moieties to con struct hydrogel n etworks with fast gelati on rate,excellent mecha nical stre ngth,and favorable stability. | Qingchen Cao Hufei Wang Xing Wang Decheng Wu | 2021 | Chinese Journal of Chemistry2021，39，8： | 4 |
| 2 | POSS-embedded supramolecular hyperbranched polymers constructed from a 1→7 branching monomer with controllable morphology transitions显示文摘The research on the supramolecular hyperbranched polymers(SHPs) that combines the advantages of supramolecular polymer and hyperbranched architecture has attracted considerable interests in many applications. Here we demonstrate a simple approach to prepare POSS-embedded supramolecular hyperbranched polymers(POSS-SHPs) with varied morphology and size by controlling monomer concentration and mixed solvents. The SHPs formations can further transfer into the core-shell structured micelles by addition of competitive guests based on the double supramolecular driving forces. | Xing Wang Yanyu Yang Linfeng Fan Fei Yang Decheng Wu | 2018 | Science China Chemistry2018，61，3： | 3 |
| 3 | Whole exome sequencing identifies an AMBN missense mutation causing severe autosomal-dominant amelogenesis imperfecta and dentin disorders显示文摘Tooth development is a complex process that involves precise and time-dependent orchestration of multiple genetic, molecular,and cellular interactions. Ameloblastin(AMBN, also named 'amelin' or 'sheathlin') is the second most abundant enamel matrix protein known to have a key role in amelogenesis. Amelogenesis imperfecta(AI [MIM: 104500]) refers to a genetically and phenotypically heterogeneous group of conditions characterized by inherited developmental enamel defects. The hereditary dentin disorders comprise a variety of autosomal-dominant genetic symptoms characterized by abnormal dentin structure affecting either the primary or both the primary and secondary teeth. The vital role of Ambn in amelogenesis has been confirmed experimentally using mouse models. Only two cases have been reported of mutations of AMBN associated with non-syndromic human AI. However, no AMBN missense mutations have been reported to be associated with both human AI and dentin disorders.We recruited one kindred with autosomal-dominant amelogenesis imperfecta(ADAI) and dentinogenesis imperfecta/dysplasia characterized by generalized severe enamel and dentin defects. Whole exome sequencing of the proband identified a novel heterozygous C-T point mutation at nucleotide position 1069 of the AMBN gene, causing a Pro to Ser mutation at the conserved amino acid position 357 of the protein. Exfoliated third molar teeth from the affected family members were found to have enamel and dentin of lower mineral density than control teeth, with thinner and easily fractured enamel, short and thick roots, and pulp obliteration. This study demonstrates, for the first time, that an AMBN missense mutation causes non-syndromic human AI and dentin disorders. | Ting Lu Meiyi Li Xiangmin Xu Jun Xiong Cheng Huang Xuelian Zhang Aiqin Hu Ling Peng Decheng Cai Leitao Zhang Buling Wu Fu Xiong | 2018 | International Journal of Oral Science2018，10，4： | 3 |
| 4 | Facile fabrication of a biocompatible composite gel with sustained release of aspirin for bone regeneration显示文摘Hydrogels are extracellular-matrix-like biomimetic materials that have wide biomedical applications in tissue engineering and drug delivery.However,most hydrogels cannot simultaneously fulfill the mechanical and cell compatibility requirements.In the present study,we prepared a semi-interpenetrating network composite gel(CG)by incorporating short chain chitosan(CS)into a covalent tetra-armed poly(ethylene glycol)network.In addition to satisfying physicochemical,mechanics,biocompatibility,and cell affinity requirements,this CG easily encapsulated acetylsalicylic acid(ASA)via electrostatic interactions and chain entanglement,achieving sustained release for over 14 days and thus promoting periodontal ligament stem cell(PDLSC)proliferation and osteogenic differentiation.In vivo studies corroborated the capacity of PDLSCs and ASA-laden CG to enhance new bone regeneration in situ using a mouse calvarial bone defect model.This might be attributed to PDLSCs and host mesenchymal stem cells expressing monocyte chemoattractant protein-1,which upregulated M2 macrophage recruitment and polarization in situ,indicating its appealing potential in bone tissue engineering. | Yunfan Zhang Xueyu Dou Lingyun Zhang Hufei Wang Ting Zhang Rushui Bai Qiannan Sun Xing Wang Tingting Yu Decheng Wu Bing Han Xuliang Deng | 2022 | Bioactive Materials2022，7，5： | 2 |
| 5 | Multifunctional microcapsules:A theranostic agent for US/MR/PAT multi-modality imaging and synergistic chemo-photothermal osteosarcoma therapy显示文摘Development of versatile theranostic agents that simultaneously integrate therapeutic and diagnostic features remains a clinical urgent.Herein,we aimed to prepare uniform PEGylated(lactic-co-glycolic acid)(PLGA)microcapsules(PB@(Fe_(3)O_(4)@PEG-PLGA)MCs)with superparamagnetic Fe3O4 nanoparticles embedded in the shell and Prussian blue(PB)NPs inbuilt in the cavity via a premix membrane emulsification(PME)method.On account of the eligible geometry and multiple load capacity,these MCs could be used as efficient multi-modality contrast agents to simultaneously enhance the contrasts of US,MR and PAT imaging.In-built PB NPs furnished the MCs with excellent photothermal conversion property and embedded Fe_(3)O_(4)NPs endowed the magnetic location for fabrication of targeted drug delivery system.Notably,after further in-situ encapsulation of antitumor drug of DOX,(PB+DOX)@(Fe_(3)O_(4)@PEG-PLGA)MCs possessed more unique advantages on achieving near infrared(NIR)-responsive drug delivery and magnetic-guided chemo-photothermal synergistic osteosarcoma therapy.In vitro and in vivo studies revealed these biocompatible(PB+DOX)@(Fe_(3)O_(4)@PEG-PLGA)MCs could effectively target to the tumor tissue with superior therapeutic effect against the invasion of osteosarcoma and alleviation of osteolytic lesions,which will be developed as a smart platform integrating multi-modality imaging capabilities and synergistic effect with high therapy efficacy. | Hufei Wang Sijia Xu Daoyang Fan Xiaowen Geng Guang Zhi Decheng Wu Hong Shen Fei Yang Xiao Zhou Xing Wang | 2022 | Bioactive Materials2022，7，1： | 2 |
| 6 | Construction of versatile multilayered composite nanoparticles from a customized nanogel template显示文摘We present a highly adaptable design platform for multi-responsive,multilayered composite nanoparticles(MC-NPs)with fine-tunable functional layers.A flexible disulfide-linked nanogel template is obtained by a controlled in-situ gelation method,enabling a high degree of control over each successive layer.From this template,we optimize“smart”biomaterials with biofunctional surfaces,tunable drug release kinetics,and magnetic or pH-responsive functionality,fabricated into MC-NPs for targeted drug release and periosteum-mimetic structures for controlled rhBMP-2 release towards bone tissue formation in-vivo.Such a versatile platform for the design of MC-NPs is a powerful tool that shows considerable therapeutic potential in clinical fields such as oncology and orthopedics. | Jian Zhang Jinpeng Jia Jimin P.Kim Fei Yang Xing Wang Hong Shen Sijia Xu Jian Yang Decheng Wu | 2018 | Bioactive Materials2018，3，1： | 1 |
| 7 | Porous Co_(2)VO_(4) Nanodisk as a High-Energy and Fast-Charging Anode for Lithium-Ion Batteries显示文摘High-energy–density lithium-ion batteries(LIBs)that can be safely fast-charged are desirable for electric vehicles.However,sub-optimal lithiation potential and low capacity of commonly used LIBs anode cause safety issues and low energy density.Here we hypothesize that a cobalt vanadate oxide,Co_(2)VO_(4),can be attractive anode material for fast-charging LIBs due to its high capacity(~1000 mAh g^(−1))and safe lithiation potential(~0.65 V vs.Li^(+)/Li).The Li+diffusion coefficient of Co2VO4 is evaluated by theoretical calculation to be as high as 3.15×10^(-10) cm^(2) s^(−1),proving Co_(2)VO_(4) a promising anode in fast-charging LIBs.A hexagonal porous Co2VO4 nanodisk(PCVO ND)structure is designed accordingly,featuring a high specific surface area of 74.57 m^(2) g^(−1) and numerous pores with a pore size of 14 nm.This unique structure succeeds in enhancing Li^(+) and electron transfer,leading to superior fast-charging performance than current commercial anodes.As a result,the PCVO ND shows a high initial reversible capacity of 911.0 mAh g^(−1) at 0.4 C,excellent fast-charging capacity(344.3 mAh g^(−1) at 10 C for 1000 cycles),outstanding long-term cycling stability(only 0.024% capacity loss per cycle at 10 C for 1000 cycles),confirming the commercial feasibility of PCVO ND in fast-charging LIBs. | Jinghui Ren Zhenyu Wang Peng Xu Cong Wang Fei Gao Decheng Zhao Shupei Liu Han Yang Di Wang Chunming Niu Yusong Zhu Yutong Wu Xiang Liu Zhoulu Wang Yi Zhang | 2022 | Nano-Micro Letters2022，14，1： | 1 |
| 8 | GEOCHEMICAL CHARACTERISTICS OF GRANITES AND ITS STRUCTURAL GENETIC ENVIRONMENT IN THE NANDAN-HECHI METALLOGENETIC BELT, NORTHWEST GUANGXI显示文摘The Nandan-Hechi metallogenetic belt is the most important tin-polymetallic producing district in China, and is the location of the Dachang super-large tin deposit. Based on the detailed field investigation and isotopic data, the stages of magmatic activity in the Nandan-Hechi metallogenetic belt have been lined out in this paper. Through the study about the geochemical characteristics of different granites, and by using ω(Al2O3)-ω(SiO2), ω(TFeO)/[ω(TFeO)+ω(MgO)]-ω(SiO2), AFM, ACF and Rb-Yb+Ta, Rb-Y+Nb, Ta-Yb, Nb-Y discrimination diagrams in combination with regional geological setting analysis, the authors carried out analyses about the structural environment for the formation of the granites, and discussed the structural environment and dynamic setting for the large scale mineralization in this area. Our study indicates that the majority of the granites in Nandan-Hechi metallogenetic belt belong to the POG type, while the later stage alaskite belongs to the RRG+CEUG type. The granites were formed at the stage of structural transformation from postorogenic phase to intraplate setting. But the major structural environment is characterized by steady regional extension. The formation age for the granites coincides with the time for this transformation, and this translation environment is favored for large-scale metallogenesis. | CAI Minghai LIANG Ting WU Decheng HUANG Huimin | 2004 | Geotectonica et Metallogenia2004，28，2： | 1 |
| 9 | Multiwalled carbon nanotube grafted with hyperbranehed polymer shell viaSCVP 显示文摘 | Hong Chunyan You Yezi Wu Decheng | 2005 | Maeremoleeules2005，38，7： | 1 |
| 10 | Polyhedral Oligomeric Silsesquioxanes(POSS)-based Hybrid Materials:Molecular Design,Solution Self.Assembly and Biomedical Applications显示文摘Owing to the tremendous advantages and unique well-defined nanoscale structure,polyhedral oligomeric silsesquioxanes(POSS)have received considerable interest in the design of novel organic-inorganic hybrid nanomaterials with all manner of prominent capabilities,which is rec-ognized as a new generation of promising materials for advanced applications of material sci-ence,engineering science and biomedical fields.Benefitting from the recent progress in combi-nation of controlled/living polymerization and emerging click chemistry,POSS-based hybrid ma-terials with ingenious design,versatile topological structure and sophisticated multifunctionality have been successfully fabricated and developed into abundant well-defined hybrid nanostruc-tures with desired physicochemical properties.Tailor-made amphiphilic molecular design and nanosized hybrid architecture provide opportunities for the self-assembly of POSS-based hybrid materials with unique hierarchical morphologies in selective solvents.Through the in-depth understanding of structure-properties relationship,POSS-based hybrid materials can achieve the modulation of precise control of self-assembling process and multi-purpose applications with improved material performances.In this review,we summarize the recent advances of POSS-based hybrid materials in molecular design,self-assembly behavior in solutions and poten-tial biomedical applications with main concerns on drug delivery,gene therapy,bioimaging and tissue engineering field.Finally,future directions and remaining challenges for further advance-ment of POSS-based hybrid materials are proposed and discussed. | Linfeng Fan Xing Wang Decheng Wu | 2021 | Chinese Journal of Chemistry2021，39，3： | 1 |
| 11 | Energy-Dissipative and Soften Resistant Hydrogels Based on Chitosan Physical Network: From Construction to Application显示文摘In spite of biological tissue-like peculiarity,multifarious functionalities and great application prospect,the low mechanics and soften behavior of hydrogels still retain a problem to be addressed for repetitive weight-bearing fields of flexible electronics,actuators,substitutions of soft tissues,wound dressing,wearable or implantable devices.Due to the distinct combination of diversity,reversibility and impressive disruption-reconstruction capacity,the chitosan physical cross-links can server as recoverable“sacrificial bonds”to construct multifarious energy-dissipative and anti-soften hydrogels and further broaden their diversified applications.In this review,we summarized the gelation mechanisms of chitosan physical networks and highlighted the chitosan physical network based hydrogels in rational design,construction principle,and structure and performance regulation.The recent progress in functional hydrogels for flexible electronics and biomaterials was systematically discussed.Overall,the review will provide comprehensive guidelines on the design principle,performance modulation and functionality construction of energy-dissipative and soften resistant hydrogels. | Yanyu Yang Decheng Wu | 2022 | Chinese Journal of Chemistry2022，40，17： | 1 |
| 12 | Blue photoluminescence from hyperbranched poly(amino ester)s显示文摘 | WU Decheng LIU Ye HE Chaobin | 2005 | Macromolecules2005，38，24： | 1 |
| 13 | Computability of meas-urable sets via effective metrics显示文摘 | WU Yongcheng DING Decheng | 2005 | Mathematical LogicQuarterly2005，51，6： | 1 |
| 14 | Computability of meas-urable sets via effective topologies显示文摘 | WU Yongcheng DING Decheng | 2006 | Archive for Mathe-matical Logic2006，45，3： | 1 |
| 15 | Insertion of type O-conserved neutralizing epitope into the foot-and-mouth disease virus type Asia1 VP1 G-H loop: effect on viral replication and neutralization phenotype显示文摘 | Haiwei Wang Mei Xue Decheng Yang Guohui Zhou Donglai Wu Li Yu | 2012 | Journal of General Virology (Pt )2012，，7： | 1 |
| 16 | pH-Controllable cyclic threading/dethreading of polypseudorotaxane obtained from cyclodextrins and poly (amino ester)显示文摘 | Guobin Sun Decheng Wu Ye Liu | 2005 | Polymer2005，46，： | 1 |
| 17 | Synthesis and Anhydrous Proton Conductivity of Poly (5-vinyltet- razole) Prepared by Free Radical Polymerization显示文摘 | Pu Hongting Wu Jie Wan Decheng | 2008 | Journal of Membrane Science2008，322，2： | 1 |
| 18 | Recent progress on fabrication and flat-band physics in 2D transition metal dichalcogenides moiré superlattices显示文摘Moiré superlattices are formed when overlaying two materials with a slight mismatch in twist angle or lattice constant. They provide a novel platform for the study of strong electronic correlations and non-trivial band topology, where emergent phenomena such as correlated insulating states, unconventional superconductivity, and quantum anomalous Hall effect are discovered. In this review, we focus on the semiconducting transition metal dichalcogenides(TMDs) based moiré systems that host intriguing flat-band physics. We first review the exfoliation methods of two-dimensional materials and the fabrication technique of their moiré structures. Secondly, we overview the progress of the optically excited moiré excitons, which render the main discovery in the early experiments on TMD moiré systems. We then introduce the formation mechanism of flat bands and their potential in the quantum simulation of the Hubbard model with tunable doping, degeneracies, and correlation strength. Finally, we briefly discuss the challenges and future perspectives of this field. | Xinyu Huang Xu Han Yunyun Dai Xiaolong Xu Jiahao Yan Mengting Huang Pengfei Ding Decheng Zhang Hui Chen Vijay Laxmi Xu Wu Liwei Liu Yeliang Wang Yang Xu Yuan Huang | 2023 | Journal of Semiconductors2023，44，1： | 0 |
| 19 | Two tandem multicomponent reactions for the synthesis of sequence-defined polymers显示文摘Multicomponent polymerizations have become powerful tools for the construction of sequence-defined polymers. Although the Passerini multicomponent reaction has been widely used in the synthesis of sequence-defined polymers, the tandem usage of the Passerini multicomponent reaction and other multicomponent reactions in one-pot for the synthesis of sequence-defined polymers has not been developed until now. In this contribution, we report the tandem usage of the Passerini three-component reaction and the three-component amine-thiol-ene conjugation reaction in one pot for the synthesis of sequence-defined polymers. The Passerini reaction between methacrylic acid, adipaldehyde, and 2-isocyanobutanoate was carried out, affording a new molecule containing two alkene units. Subsequently, an amine and a thiolactone were added to the reaction system, whereupon the three-component amine-thiol-ene conjugating reaction occurred to yield a sequence-defined polymer. This method offers more rapid access to sequence-defined polymers with high molecular diversity and complexity. | Lu Yang Ze Zhang Bofei Cheng Yezi You Decheng Wu Chunyan Hong | 2015 | Science China Chemistry2015，58，11： | 0 |
| 20 | Exploring cutting-edge hydrogel technologies and their biomedical applications显示文摘Hydrogels have emerged as three-dimensional biomaterials with potential biomedical applications in numerous fields including drug delivery and tissue engineering.They have particularly garnered great interest from researchers due to their excellent biocompatibility,ability to encapsulate,protect,and deliver bioactive therapeutics,capacity for sustained release,and their ability to act as implantable scaffolds and support tissue regeneration.This special issue,consisting of eight papers,addresses some of the greatest challenges in hydrogel technology and showcases its capabilities,focusing on the applications of hydrogels in bone regeneration[1][2],stem cell therapy[3],hemostasis[4],stroke[5],cancer treatments[6][7],and biological activities in general[8]. | Decheng Wu Xiaoyang Xu | 2018 | Bioactive Materials2018，3，4： | 0 |
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