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| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Oral probiotic VSL #3 attenuates the circulatory disturbances of patients with cirrhosis and ascites显示文摘 | Diego Rincón Javier Vaquero Ana Hernando Evelyn Galindo Cristina Ripoll Marta Puerto Magdalena Salcedo Rubén Francés Ana Matilla María V. Catalina Gerardo Clemente José Such Rafael Ba?ares | 2014 | Liver Int2014，，10： | 2 |
| 3 | Investigation of aortic coronary artery bypass bu mutislice spiral computed tomography with electocardiographic gated image reconstruction 显示文摘 | Dieter R Stenfan N Evelyn W | 2001 | Am J Cardiol2001，86，7： | 1 |
| 4 | Effect of Droplet Morphology on Growth Dynamics and Heat Transfer During Condensation on Superhydrophobic Nanostructured Surfaces 显示文摘 | Nenad M Ryan E Evelyn N Wang | 2012 | Nano2012，6，2： | 1 |
| 5 | Investigation of aortic coronary artery bypass bu mutislic spiral computed tomography with electrocardiographic gated image reconstruction 显示文摘 | Dieter R Stenfan N Evelyn W | 2001 | Am J Cardiol2001，86，7： | 1 |
| 6 | Occurrence of lysozyme in the eggs of coho salmon Oncorhynchus kisutch显示文摘 | Yousif A N Albright L J Evelyn T P T | 1991 | Dis Aquat Organ1991，10，： | 1 |
| 7 | Expression of aldehyde dehydrogenase 1 as a marker of mammary stem cells in benign and malignant breast lesions of Ghanaian women显示文摘 | Theresa Schwartz Azadeh Stark Judy Pang Baffour Awuah Celina G. Kleer Solomon Quayson Stephanie Kingman Francis Aitpillah Francis Abantanga Evelyn Jiagge Joseph K. Oppong Ernest Osei‐Bonsu Iman Martin Xiaowei Yan Kathy Toy Ernest Adjei Max Wicha Lisa A. N | 2012 | Cancer2012，，3： | 1 |
| 8 | Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin-2from endothelial cells显示文摘 | Thomas K Evelyn E Rainer N | 2012 | Cardiovascular Research2012，94，3： | 1 |
| 9 | Molecular diagnosis of B- and T-cell lymphomas:fundamental principles and clinical applications 显示文摘 | William N Rezuke T Evelyn C | 1997 | Clin Chem1997，43，10： | 1 |
| 10 | Hy- pertension management in an outpatient clinic at the In-stitute of Cardiology of Abidjan (Ivory Coast) 显示文摘 | Euloge K K Yves N K N Evelyne A T | 2011 | Archives of Cardiovascular Diseases2011，104，11： | 1 |
| 11 | Plaque Composition and its Relationship With Acknowledged Shear Stress Patterns in Coronary Arteries显示文摘 | Gastón A. Rodriguez-Granillo Héctor M. García-García Jolanda Wentzel Marco Valgimigli Keiichi Tsuchida Wim van der Giessen Peter de Jaegere Evelyn Regar Pim J. de Feyter Patrick W. Serruys | 2006 | Journal of the American College of Cardiology2006，，4： | 1 |
| 12 | Investigation of aortic coronary artery bypass grafts by multislice spiral computed tomography with electrocardiographically gated image reconstruction显示文摘 | DIETER R STENFAN N EVELYN W | 2001 | Am J Cardiol2001，86，7： | 1 |
| 13 | CHIR- 258 :a potent inhibitor of FLT3 kinase in experimental tumor xenograft models of human acute myelogenous leukemia显示文摘 | DANIEL E JING Peng EVELYN N G | 2005 | Clin Cancer Res2005，11，14： | 1 |
| 14 | Occurrence of lysozyme in the eggs of coho salmon Oncorhynchus kisutch显示文摘 | Yousif A N Albright L J Evelyn T P T | 1991 | Diseases of Aquatic Organisms1991，10，： | 1 |
| 15 | Expression of aldehyde dehydrogenase 1 as a marker of mammary stem cells in benign and malignant breast lesions of Ghanaian women显示文摘 | Theresa Schwartz Azadeh Stark Judy Pang Baffour Awuah Celina G. Kleer Solomon Quayson Stephanie Kingman Francis Aitpillah Francis Abantanga Evelyn Jiagge Joseph K. Oppong Ernest Osei‐Bonsu Iman Martin Xiaowei Yan Kathy Toy Ernest Adjei Max Wicha Lisa A. N | 2012 | Cancer2012，，3： | 1 |
| 16 | In vitroevidence for the antibacterial role of lysozyme in sal- monid eggs 显示文摘 | Yousif A N Albright L J Evelyn T P T | 1994 | Diseases of Aquatic Organisms1994，19，1： | 1 |
| 17 | In vitro evidence for the antibacterial role of lysozyme in salmonid eggs 显示文摘 | Yousif A N Albright L J Evelyn T P T | 1994 | Dis Aquat Organ1994，19，： | 1 |
| 18 | In vitro evidence for the antibacterial role of lysozyme in salmonid eggs显示文摘 | Yousif A N Albright L J Evelyn T P T | 1994 | Disease of Aquatic Organisms1994，19，： | 1 |
| 19 | Occurrence of lysozyme in the eggs of coho salmon Oncorhynchus kisutch显示文摘 | Yousif A N Albright L J Evelyn T P T | 1991 | Disease of Aquatic Organisms1991，10，： | 1 |
| 20 | In vitro evidence for the antibacterial role of lysozyme in salmonid eggs 显示文摘 | Yousif A N Albright L J Evelyn T P T | 1994 | Diseases of Aquatic Organisms1994，19，： | 1 |
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