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您的检索式：作者名="FEN Xiaoxi"
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| 1 | Structure Styles of Mesozoic-Cenozoic U-bearing Rock Series in Northern China显示文摘In Northern China,sandstone-type uranium(U) deposits are mostly developed in MesozoicCenozoic basins. These U deposits are usually hosted in unvarying horizons within the basins and exhibit typical U-forming sedimentary associations,which is referred to as U-bearing rock series. This study describes the structural features of U-bearing rock series within the main Mesozoic-Cenozoic Uproducing continental basins in Kazakhstan,Uzbekistan,and Russia in the western segment of the Central Asian Metallogenic Belt(CAMB),and Northern China in the eastern segment of the CAMB. We analyze the basic structural conditions and sedimentary environments of U-bearing rock series in Northern China and classify their structural styles in typical basins into river valley,basin margin,and intrabasin uplift margin types. The intrabasin uplift margin structural style proposed in this study can be used to indicate directions for the exploration of sandstone-type U deposits hosted in the center of a basin. At the same time,the study of structural style provides a new idea for exploring sandstone-type U deposits in Mesozoic-Cenozoic basins and it is of great significance to prospecting of sandstone-type uranium deposits. | JIN Ruoshi MIAO Peisen SIMA Xianzhang LI Jianguo ZHAO Hualei ZHAO Fengqing FEN Xiaoxi CHEN Yin CHEN Lulu ZHAO Lijun ZHU Qiang | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 12 |
| 2 | Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway in vivo and in vitro显示文摘Autoimmune hepatitis(AIH)is a severe globally distributed liver disease that could occur at any age.Human menstrual blood-derived stem cells(MenSCs)have shown therapeutic effect in acute lung injury and liver failure.However,their role in the curative effect of AIH remains unclear.Here,a classic AIH mouse model was constructed through intravenous injection with concanavalin A(Con A).MenSCs were intravenously injected while Con A injection in the treatment groups.The results showed that the mortality by Con A injection was significantly decreased by MenSCs treatment and liver function tests and histological analysis were also ameliorated.The results of phosphoproteomic analysis and RNA-seq revealed that MenSCs improved AIH,mainly by apoptosis and c-Jun N-terminal kinase/mitogen-activated protein signaling pathways.Apoptosis analysis demonstrated that the protein expression of cleaved caspase 3 was increased by Con A injection and reduced by MenSCs transplantation,consistent with the TUNEL staining results.An AML12 co-culture system and JNK inhibitor(SP600125)were used to verify the JNK/MAPK and apoptosis signaling pathways.These findings suggested that MenSCs could be a promising strategy for AIH. | Fen Zhang Lanlan Xiao Ya Yang Menghao Zhou Yalei Zhao Zhongyang Xie Xiaoxi Ouyang Feiyang Ji Shima Tang Lanjuan Li | 2023 | Frontiers of Medicine2023，17，3： | 0 |
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