|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity显示文摘Obesity and associated metabolic diseases are characterized by a chronic low-grade inflammatory state with the infiltration of many inflammatory cells,especially macrophages.Immune molecules,including some cytokines,have a close relationship with metabolism.Interleukin(IL)-25 is a member of the IL-17 cytokine family that can regulate macrophages and alleviate some metabolic dysfunction;however,its role and mechanisms in lipid metabolism remain to be extensively clarified.Human serum and liver biopsy specimens,high-fat diet-induced obesity mice and DB/DB(Lepr−/−)animal models were used to examine IL-25 expression in obesity and nonalcoholic fatty liver diseases(NAFLD).To observe the role of IL-25 in lipid metabolism,model mice were administered with IL-25 or adoptively transferred with IL-25-educated macrophages in vivo,whereas bone marrow-derived macrophages,the macrophage cell line RAW264.7 and adipocytes differentiated from 3T3-L1 were used in vitro.IL-25 was decreased in NAFLD patients and obese mice.In addition,IL-25 reduced body weight gain and lipid accumulation,enhanced lipid uptake by macrophages and increased the expression of lipolysis andβ-oxidation enzymes via alternatively activating macrophages.IL-25 also promoted lipolysis and suppressed lipogenesis in adipocytes co-cultured with the IL-25-educated macrophages.Furthermore,IL-25 improved the mitochondrial respiratory capacity and oxygen consumption rate of macrophages and produced more NAD+/NADH and ATP.In conclusion,IL-25 can stimulate M2 macrophage polarization and thereby promote lipolysis and mitochondrial respiratory capacity,highlighting the potential for IL-25 to be used as a therapeutic agent against obesity and associated metabolic syndromes. | Juan Feng Lingyi Li Zhiying Ou Qiao Li Baoyong Gong Zhenxian Zhao Weiwei Qi Ti Zhou Jun Zhong Weibin Cai Xia Yang Aiping Zhao Guoquan Gao Zhonghan Yang | 2018 | Cellular & Molecular Immunology2018，15，5： | 10 |
| 2 | REE geochemical characteristics of the No. 302 uranium deposit in northern Guangdong, South China显示文摘The No. 302 uranium deposit, located in Guangdong Province, is a typical granite-type uranium ore deposit. REE geochemical characteristics of the wall rocks, pitchblende, altered rocks, calcite and fluorite from this deposit have been systematically studied in this paper. The result showed that the alkali-metasomatic granites and other altered rocks have the same REE distribution patterns as Indosinian granites. It is indicated that the hydrothermal ore-forming solution had altered the Indosinian granites, and ore-forming materials may directly originate from the Indosinian granites. Calcite and fluorite of different stages are the products derived from the same source but different stages. The evolution and degassing of the mineralizing solution might induce LREE enrichment to varying degree. Mantle fluid and a large volume of mineralizer may be the crucial factors controlling uranium mineralization, and the hydrothermal solution with mineralizer played an important role in U transport and concentration. Meanwhile, the degassing of CO2 might promote U and REE precipitation. | ZHANG Guoquan HU Ruizhong BI Xianwu FENG Haisheng SHANG Pengqiang TIAN Jianji | 2007 | Chinese Journal Of Geochemistry2007，26，4： | 8 |
| 3 | Second-harmonic generation using d(33)in periodically poled lithium niobate microdisk resonators显示文摘A fabrication process allowing for the production of periodically poled lithium niobate(PPLN)photonic devices with any domain pattern and unit size down to 200 nm is developed by combining semiconductor fabrication techniques and piezo-force-microscopy tips polarization.Based on this fabrication process,PPLN microdisk resonators with quality factors of 8×10~4 were fabricated from a Z-cut lithium niobate film.Second-harmonic generation(SHG)utilizing d(33)in the whole cavity was demonstrated in a PPLN microdisk with a 2μm-spatialperiod radial domain pattern.The SHG conversion efficiency was measured to be 1.44×10^(-5)m W^(-1).This work paves the way to fabricate complex PPLN photonic devices and to obtain efficient nonlinear optical effects that have wide applications in both classical and quantum optics. | ZHENZHONG HAO LI ZHANG WENBO MAO ANG GAO XIAOMEI GAO FENG GAO FANG BO GUOQUAN ZHANG JINGJUN XU | 2020 | Photonics Research2020，8，3： | 6 |
| 4 | Periodically poled lithium niobate whispering gallery mode microcavities on a chip显示文摘In this study, we investigate the fabrication of periodically poled lithium niobate(PPLN) microdisk cavities on a chip. These resonators are fabricated from a PPLN film with a 16 μm poling period on insulator using conventional microfabrication techniques.The quality factor of the PPLN microdisk resonators with a 40-μm radius and a 700-nm thickness is 6.7×10~5. Second harmonic generation(SHG) with an efficiency of 2.2×10^(-6) mW(-1) is demonstrated in the fabricated PPLN microdisks. The nonlinear conversion efficiency could be considerably enhanced by optimizing the period and pattern of the poled structure and by improving the cavity quality factors. | ZhenZhong Hao Li Zhang Ang Gao WenBo Mao XiaoDan Lyu XiaoMei Gao Fang Bo Feng Gao GuoQuan Zhang JingJun Xu | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，11： | 5 |
| 5 | Integrated lithium niobate single-mode lasers by the Vernier effect显示文摘Microcavity lasers based on erbium-doped lithium niobate on insulator(LNOI),which are key devices for LNOI integrated photonics,have attracted significant attention recently.In this study,we report the realization of a C-band single-mode laser using the Vernier effect in two coupled erbium-doped LNOI microrings with different radii under the pump of a 980-nm continuous laser.The laser,operating stably over a large range of pumping power,has a pump threshold of about 200μW and a side-mode suppression ratio exceeding 26 dB.The high-performance LNOI single-mode laser will promote the development of lithium niobate integrated photonics. | Ru Zhang Chen Yang ZhenZhong Hao Di Jia Qiang Luo DaHuai Zheng HongDe Liu XuanYi Yu Feng Gao Fang Bo YongFa Kong GuoQuan Zhang JingJun Xu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，9： | 4 |
| 6 | Sum-frequency generation in on-chip lithium niobate microdisk resonators显示文摘We report the first observation, to the best of our knowledge, of sum-frequency generation in on-chip lithium niobate microdisk resonators. The sum-frequency signal in the 780 nm band, distinct in wavelength from secondharmonic signals, was obtained in lithium niobate microresonators under the pump of two individual 1550 nm band lasers. The sum-frequency conversion efficiency was measured to be 1.4 × 10^(-7) mW^(-1). The dependence of the intensities of the nonlinear signals on the total pump power and the wavelength of one pump laser was investigated while fixing the wavelength of the other. This work paves the way for applications of on-chip lithium niobate microdisk resonators ranging from infrared single-photon detection to infrared spectroscopy. | ZHENZHONG HAO JIE WANG SHUQIONG MA WENBO MAO FANG BO FENG GAO GUOQUAN ZHANG JINGJUN XU | 2017 | Photonics Research2017，5，6： | 3 |
| 7 | Nanoimprint Lithography:A Processing Technique for Nanofabrication Advancement显示文摘Nanoimprint lithography(NIL) is an emerging micro/nano-patterning technique,which is a high-resolution,high-throughput and yet simple fabrication process.According to International Technology Roadmap for Semiconductor(ITRS),NIL has emerged as the next generation lithography candidate for the22 nm and 16 nm technological nodes.In this paper,we present an overview of nanoimprint lithography.The classfication,research focus,critical issues,and the future of nanoimprint lithography are intensively elaborated.A pattern as small as 2.4 nm has been demonstrated.Full-wafer nanoimprint lithography has been completed on a 12-inch wafer.Recently,12.5 nm pattern resolution through soft molecular scale nanoimprint lithography has been achieved by EV Group,a leading nanoimprint lithography technology supplier. | Weimin Zhou Guoquan Min Jing Zhang Yanbo Liu Jinhe Wang Yanping Zhang Feng Sun | 2011 | Nano-Micro Letters2011，3，2： | 3 |
| 8 | Phthalate esters (PAEs): Emerging organic contaminants in agricultural soils in peri-urban areas around Guangzhou, China显示文摘 | Feng Zeng Kunyan Cui Zhiyong Xie Lina Wu Min Liu Guoquan Sun Yujun Lin Danling Luo Zunxiang Zeng | 2008 | Environmental Pollution2008，，2： | 2 |
| 9 | Mode characteristics of silver-coated inverted-wedge silica microdisks显示文摘The characteristics of whispering gallery modes(WGM) in silver-coated inverted-wedge silica microdisks are theoretically investigated by using finite element method. Dielectric TE mode always exists in silver-coated inverted-wedge resonators; dielectric TM mode tends to couple with SPP modes; only pure interior surface plasmonic polariton(SPP) mode but not pure exterior SPP mode is observed in contrast to the metal-coated cylindrical and toroidal resonators. The dependence of quality factor of different kinds of WGMs on the radius of the resonator and the thickness of the coated silver layer are systematically analyzed. We find that the quality factors of the hybrid WGMs associated with SPP mode can reach 104. The maximum light intensity enhancement in ambient for a hybrid mode consisting of a dielectric TM mode and an exterior SPP mode can be obtained when a silver film of thickness ~40 nm is deposited. The silver-coated inverted-wedge silica resonators may be widely applied in sensing and surface enhanced Raman scattering. | BO Fang WANG XiaoOu LI Ying GAO Feng ZHANG GuoQuan XU JingJun | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，11： | 2 |
| 10 | Full-spectrum responsive photocatalytic activity via non-noble metal Bi decorated mulberry-like BiVO_(4)显示文摘Due to its appropriate bandgap(~2.4 e V)and efficient light absorption,bismuth vanadate(Bi VO_(4))shows promising photocatalysis activity.However,the charge carrier recombination and poor electron transmission often induce poor photocatalytic performance.Herein,we report a new method to in-situ synthesize non-noble metal Bi decorated mulberry-like Bi VO_(4)by a two-step calcination process.Comprehensive characterizations reveal that non-noble metal Bi nanoparticles grown in-situ on Bi VO_(4)result in the red-shift of the absorbance edge,greatly extending the light absorption from the ultraviolet into the near-infrared region.The surface plasmon resonance excitation of Bi nanoparticles and synergetic effects between Bi and Bi VO_(4)effectively improve the photocatalytic efficiency and promote the separation of photoinduced electron-hole pairs in mulberry-like Bi VO_(4).Density functional theory(DFT)calculation results further verify that the electrons are transferred from Bi to Bi VO_(4)and the formation of·OH radical in Bi/Bi VO_(4)is attributed to the lower simulated free energy,which supports our experimental outcomes.This work provides a novel strategy to enhance light absorption and promote efficient solar utilization of photocatalysts for practical applications. | Yaxin Bi Yanling Yang Xiao-Lei Shi Lei Feng Xiaojiang Hou Xiaohui Ye Li Zhang Guoquan Suo Siyu Lu Zhi-Gang Chen | 2021 | Journal of Materials Science & Technology2021，，24： | 2 |
| 11 | Construction of SnS2/SnO2 heterostructures with enhanced potassium storage performance显示文摘Increasing attention has been focused on potassium ion batteries(KIBs) as promising energy-sto rage system(ESS) owing to the abundance and low-cost of potassium resources.Here,SnS2/SnO2 hete rostructures were successfully fixed onto stainless steel mesh(SnS2/SnO2/SSM) through a facile two-step hydrothermal method and used as anodes for KIBs.Due to the advantages of SnS2/SnO2 heterostructures and good conductivity of SSM substrate,the SnS2/SnO2/SSM anodes display enhanced electrochemical performance.The SnS2/SnO2/SSM anodes deliver specific capacity of 394 mA h g^-1 at 50 mA g^-1 over 100 cycles,better than SnO2/SSM.Even at 500 mA g^-1 after 250 cycles,high capacity of 155 mA h g^-1 can still be obtained. | Guoquan Suo Dan Li Lei Feng Xiaojiang Hou Xiaohui Ye Li Zhang Qiyao Yu Yanling Yang Wei(Alex)Wang | 2020 | Journal of Materials Science & Technology2020，52，20： | 1 |
| 12 | Phthalate esters (PAEs): Emerging organic contaminants in agricultural soils in peri-urban areas around Guangzhou, China显示文摘 | Feng Zeng Kunyan Cui Zhiyong Xie Lina Wu Min Liu Guoquan Sun Yujun Lin Danling Luo Zunxiang Zeng | 2008 | Environmental Pollution2008，，2： | 1 |
| 13 | Hot compressive deformation behavior of a new hot isostatically pressed Ni–Cr–Co based powder metallurgy superalloy显示文摘 | Kai Wu Guoquan Liu Benfu Hu Feng Li Yiwen Zhang Yu Tao Jiantao Liu | 2010 | Materials and Design2010，，： | 1 |
| 14 | Simultaneous determination of 45 pesticides in fruit and vegetable using an improved QuEChERS method and on-line gel permeation chromatography–gas chromatography/mass spectrometer显示文摘 | Dasheng Lu Xinlei Qiu Chao Feng Yu’e Jin Yuanjie Lin Libei Xiong Yimin Wen Dongli Wang Guoquan Wang | 2012 | Journal of Chromatography B2012，，： | 1 |
| 15 | Thermoelectric performance enhancement by manipulation of Sr/Ti doping in two sublayers of Ca_(3)Co_(4)O_(9)显示文摘Thermoelectric(TE)performance of Ca_(3)Co_(4)O_(9)(CCO)has been investigated extensively via a doping strategy in the past decades.However,the doping sites of different sublayers in CCO and their contributions to the TE performance remain unrevealed because of its strong correlated electronic system.In this work,Sr and Ti are chosen to realize doping at the[Ca_(2)CoO_(3)]and[CoO_(2)]sublayers in CCO.It was found that figure of merit(ZT)at 957 K of Ti-doped CCO was improved 30% than that of undoped CCO whereas 1 at% Sr doping brought about a 150% increase in ZT as compared to undoped CCO.The significant increase in electronic conductivity and the Seebeck coefficient are attributed to the enhanced carrier concentration and spin-entropy of Co^(4+) originating from the Sr doping effects in[Ca_(2)CoO_(3)]sublayer,which are evidenced by the scanning electron microscope(SEM),Raman,Hall,and X-ray photoelectron spectroscopy(XPS)analysis.Furthermore,the reduced thermal conductivity is attributed to the improved phonon scattering from heavier Sr doped Ca site in[Ca_(2)CoO_(3)]sublayer.Our findings demonstrate that doping at Ca sites of[Ca_(2)CoO_(3)]layer is a feasible pathway to boost TE performance of CCO material through promoting the electronic conductivity and the Seebeck coefficient,and reducing the thermal conductivity simultaneously.This work provides a deep understanding of the current limited ZT enhancement on CCO material and provides an approach to enhance the TE performance of other layered structure materials. | Li ZHANG Yichen LIU Thiam Teck TAN Yi LIU Jian ZHENG Yanling YANG Xiaojiang HOU Lei FENG Guoquan SUO Xiaohui YE Sean LI | 2020 | Journal of Advanced Ceramics2020，9，6： | 1 |
| 16 | Hydrolysis hydrogen production mechanism of Mg10Ni10Ce alloy surface modified by SnO_(2) nanotubes in different aqueous systems显示文摘(Mg-10wt%Ni)-10wt%Ce(Mg10Ni10Ce)was ball-milled with SnO_(2)nanotubes and Mg10Ni10Ce-xSnO_(2)(x¼0,5,10 and 15 wt%)composites have been prepared.The phase compositions,microstructures,morphologies and hydrolysis H2 generation performance in different aqueous systems(distilled water,tap water and simulated seawater)have been investigated and the corresponding hydrolysis mechanism of Mg10Ni10Ce and Mg10Ni10CeeSnO_(2)has been proposed.Adding a small amount of SnO_(2)nanotubes can significantly enhance the hydrolysis reaction of Mg10Ni10Ce,especially the initial hydrolysis kinetics and the final H_(2) generation yield.Unfortunately,the Mg10Ni10Ce-xSnO_(2)hardly reacts with distilled water at room temperature.The hydrolysis reaction rate of Mg10Ni10Cee5SnO_(2)composite in tap water is still very slow with only 17.3%generation yield after 1 h at 303 K.Fortunately,in simulated seawater(3.5 wt%NaCl solution),the hydrolytic H2 generation behavior of the Mg10Ni10Cee5SnO_(2)composite has been greatly improved,which can release as high as 468.6 mL g^(-1 )H_(2) with about 60.9%generation yield within 30 s at 303 K.The Cl destroys the passivation layer on MgeNieCe alloy surface and the added SnO_(2)nanotubes accelerate the hydrolysis reaction rate and enhance the H2 generation yield.The Mg10Ni10Cee5SnO_(2)composite can rapidly generate a large amount of H2 in simulated seawater in a short time,which is expected to be applied on portable H2 generators in the future. | Xiaojiang Hou Lu Yang Kaiming Hou Hongchang Shi Lei Feng Guoquan Suo Xiaohui Ye Li Zhang Yanling Yang | 2021 | Green Energy & Environment2021，6，1： | 1 |
| 17 | Polarization-modified Fano line shape spectrum with a single whispering gallery mode显示文摘Using the HE11Xand HE11Ymodes in a tapered fiber(TF)and the whispering gallery mode(WGM)in a microsphere resonator,Fano line-shape spectra were theoretically described and experimentally observed in this study.The line shapes of the spectra can be tuned to form a Lorentz notch,various Fano line shapes,and the Lorentz peak by controlling the polarizations at the input and output ports of the TF.The relative position or the size of the waveguide and WGM resonator do not need to be accurately controlled to produce these effects.The proposed configuration is suitable for mass production and will improve the performance of the devices in which it is applied. | PengFa Chang BoTao Cao LiGang Huang JiWei Li Yue Hu Feng Gao WenDing Zhang Fang Bo XuanYi Yu GuoQuan Zhang JingJun Xu | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，1： | 1 |
| 18 | Vibration characteristic investigation of counter-rotating dual-rotor in aero-engine显示文摘 | FENG GUOQUAN ZHOU BAIZHUO LUO GUIHUO | 2012 | Transactions of Nanjing Uni- verstity of Aeronautics & Astronautics2012，27，： | 1 |
| 19 | Differences of ultrasonographic enthesitis between patients with non-radiographic axial spondylarthritis and ankylosing spondylitis显示文摘To the Editor:Spondyloarthritis(SpA)is the umbrella term for a broad spectrum of inflammatory rheumatic diseases with different clinical manifestations and characteristic imaging features.Furthermore,enthesitis is considered a pathological,clinical,and imaginable hallmark of the SpA.In addition to ineffective clinical evaluation techniques of enthesitis,there are useful imaging methods to assess enthesitis,such as whole-body magnetic resonance imaging[1]and ultrasound(US)[2]examination.US has the advantage of real-time imaging and high-cost effectiveness performance.The difference in enthesitis detected by US between non-radiographic-axial SpA(nr-axSpA)and radiographic-axSpA/ankylosing spondylitis(AS)has been seldom researched.Recently,we compared the prevalence and severity of enthesitis between nr-axSpA and AS. | Juan Li Min Wang Fenghuang Xu Guoquan Li Feng Ye | 2022 | Chinese Medical Journal2022，135，21： | 0 |
| 20 | H_2 generation kinetics/thermodynamics and hydrolysis mechanism of high-performance La-doped Mg-Ni alloys in Na Cl solution——A large-scale and quick strategy to get hydrogen显示文摘In this work,La-doped Mg-Ni multiphase alloys were prepared by resistance melting furnace(RMF)and then modified by high-energy ball milling(HEBM).The hydrolysis H_(2) generation kinetics/thermodynamics of prepared alloys in Na Cl solutions have been investigated with the help of nonlinear and linear fitting by Avrami-Erofeev and Arrhenius equations.Combining the microstructure information before and after hydrolysis and thermodynamics fitting results,the hydrolysis H_(2) generation mechanism based on nucleation&growth has been elaborated.The final H_(2) generation capacities of 0La,5La,10La and 15 La alloys are 677,653,641 and 770 m L·g^(-1)H_(2) in 240 min at291 K,respectively.While,the final H_(2) generation capacities of HEBM 0La,5La,10La and 15 La alloys are 632,824,611 and 653 m L·g^(-1)H_(2) in 20 min at 291 K,respectively.The as-cast 15La alloy and HEMB 5La alloy present the best H_(2) production rates and final H_(2) production capacities,especially the HEBM 5La can rapidly achieve high H_(2) generation capacity(670 and 824 m L·g^(-1)H_(2) )at low temperature(291 K)within short time(5 and 20 min).The difference between the H_(2) generation capacities is mainly originated from the initial nucleation rate of Mg(OH)_(2) and the subsequent processes affected by the microstructures and phase compositions of the hydrolysis alloys.Relative low initial nucleation rate and fully growth of Mg(OH)_(2) nucleus are the premise of high H_(2) generation capacity due to the hydrolysis H_(2) generation process consisted by the nucleation,growth and contacting of Mg(OH)_(2) nucleus.To utilization H_(2) by designing solid state H_(2) generators using optimized Mg-based alloys is expected to be a feasible H_(2) generation strategy at the moment. | Xiaojiang Hou Hongchang Shi Lu Yang Kaiming Hou Yi Wang Lei Feng Guoquan Suo Xiaohui Ye Li Zhang Yanling Yang | 2021 | Journal of Magnesium and Alloys2021，9，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员