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| 1 | Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide analogs显示文摘 | Fengmin Lu Jie Wang Xiangmei Chen Dongping Xu Ningshao Xia | 2017 | Frontiers of Medicine2017，11，4： | 28 |
| 2 | Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease显示文摘Netrin-1,an axon guidance factor,and its receptor UNC5B play important roles in axonal development and angiogenesis.This study examined netrin-1 and UNC5B expression in kidneys with diabetic kidney disease (DKD) and investigated their roles in angiogenesis.Netrin-1 and UNC5B were upregulated in streptozotocininduced DKD Wistar rats,and their expression was compared with that in healthy controls.However,exogenous netrin-1 in UNC5B-depleted human renal glomerular endothelial cells (HRGECs) inhibited cell migration and tubulogenesis.This effect was likely associated with SRC pathway deactivation.Netrin-1 treatment also eliminated the pro-angiogenic effects of exogenous VEGF-165 on UNC5B-silenced HRGECs.These results indicate that UNC5B antagonizes netrin-1 and that UNC5B upregulation contributes partly to enhancing angiogenesis in DKD.Therefore,introducing exogenous netrin-1 and depleting endogenous UNC5B are potential strategies for reducing the incidence of early angiogenesis and mitigating kidney injury in DKD. | Xiaojing Jiao Dong Zhang Quan Hong Lei Yan Qiuxia Han Fengmin Shao Guangyan Cai Xiangmei Chen Hanyu Zhu | 2020 | Frontiers of Medicine2020，14，3： | 7 |
| 3 | Uranium Provinces in China显示文摘Three uranium provinces are recognized in China, the Southeast China uranium province, the Northeast China-Inner Mongolia uranium province and the Northwest China (Xinjiang) uranium province. The latter two promise good potential for uranium resources and are major exploration target areas in recent years. There are two major types of uranium deposits: the Phanerozoic hydrothermal type (vein type) and the Meso-Cenozoic sandstone type in different proportions in the three uranium provinces. The most important reason or prerequisite for the formation of these uranium provinces is that Precambrian uranium-enriched old basement or its broken parts (median massifs) exists or once existed in these regions, and underwent strong tectonomagmatic activation during Phanerozoic time. Uranium was mobilized from the old basement and migrated upwards to the upper structural level together with the acidic magma originating from anatexis and the primary fluids, which were then mixed with meteoric water and resulted in | CHEN Zhaobo ZHAO Fengmin XIANG Weidong CHEN Yuehui | 2000 | Acta Geologica Sinica(English Edition)2000，74，3： | 7 |
| 4 | Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine显示文摘 | Jie Chen Zhenglun Liang Fengmin Lu Xin Fang Shuang Liu Ying Zeng Fengcai Zhu Xiangmei Chen Tao Shen Jie Li Hui Zhuang | 2010 | Vaccine2010，，4： | 1 |
| 5 | Genetic polymorphisms of CXCR5 and CXCL13 are associated with non-responsiveness to the hepatitis B vaccine显示文摘 | Zhaojun Duan Xiangmei Chen Zhenglun Liang Ying Zeng Fengcai Zhu Lu Long Malcolm A. McCrae Hui Zhuang Tao Shen Fengmin Lu | 2014 | Vaccine2014，，41： | 1 |
| 6 | Enhancement of bubble absorption process using a CNTs-ammonia binary nanofluid显示文摘 | Ma Xuehu Su Fengmin Chen Jiabin | 2009 | International Communi cations in Heat and Mass Transfer2009，36，： | 1 |
| 7 | Nvestigation on SnO2 Nanopowders Stored for Different Time and BaTiO3 Modification显示文摘 | Fengmin Liu Baofu Quan Lihua Chen | 2004 | Materials Chemistry & Physics2004，87，： | 1 |
| 8 | The function of targeted host genes determines the oncogenicity of HBV integration in hepatocellular carcinoma显示文摘 | Xiaojun Li Jiangbo Zhang Ziwei Yang Jingting Kang Suzhen Jiang Ting Zhang Tingting Chen Meng Li Xiangmei Chen Malcolm A. McCrae Hui Zhuang Fengmin Lu | 2013 | Journal of Hepatology2013，，： | 1 |
| 9 | Preparation and gas sensing properties of hierarchical flower-like In 2 O 3 microspheres显示文摘 | Xiumei Xu Peilu Zhao Dawei Wang Peng Sun Lu You Yanfeng Sun Xishuang Liang Fengmin Liu Hong Chen Geyu Lu | 2013 | Sensors & Actuators: B. Chemical2013，，： | 1 |
| 10 | 1B50-1, a mAb Raised against Recurrent Tumor Cells, Targets Liver Tumor-Initiating Cells by Binding to the Calcium Channel α2δ1 Subunit显示文摘 | Wei Zhao Limin Wang Haibo Han Kemin Jin Na Lin Ting Guo Yangde Chen Heping Cheng Fengmin Lu Weigang Fang Yu Wang Baocai Xing Zhiqian Zhang | 2013 | Cancer Cell2013，，： | 1 |
| 11 | Heat and mass transfer enhancement of the bubble absorption for a binary nanofluid显示文摘 | Xuehu Ma Fengmin Su Jiabin Chen | 2007 | Journal of Mechanical Science and Technology2007，，21： | 1 |
| 12 | Heat and mass transfer enhancement of the bubble absorption for a binary nanofluid显示文摘 | Ma Xuehu Su Fengmin Chen Jiabin | 2007 | Journal of Mechancial Science and Technology2007，21，： | 1 |
| 13 | Heat and mass transfer enhancement of the bubble absorption for a binary nanofluid显示文摘 | Ma Xuehu Su Fengmin Chen Jiabin | | 0，，11： | 1 |
| 14 | 1B50-1, a mAb Raised against Recurrent Tumor Cells, Targets Liver Tumor-Initiating Cells by Binding to the Calcium Channel α2δ1 Subunit显示文摘 | Wei Zhao Limin Wang Haibo Han Kemin Jin Na Lin Ting Guo Yangde Chen Heping Cheng Fengmin Lu Weigang Fang Yu Wang Baocai Xing Zhiqian Zhang | 2013 | Cancer Cell2013，，4： | 1 |
| 15 | RNA binding protein TIAR modulates HBV replication by tipping the balance of pgRNA translation显示文摘The pregenomic RNA(pgRNA)of hepatitis B virus(HBV)serves not only as a bicistronic message RNA to translate core protein(Cp)and DNA polymerase(Pol),but also as the template for reverse transcriptional replication of viral DNA upon packaging into nucleocapsid.Although it is well known that pgRNA translates much more Cp than Pol,the molecular mechanism underlying the regulation of Cp and Pol translation efficiency from pgRNA remains elusive. | Ting Zhang Huiling Zheng Danjuan Lu Guiwen Guan Deyao Li Jing Zhang Shuhong Liu Jingmin Zhao Ju-Tao Guo Fengmin Lu Xiangmei Chen | 2023 | Signal Transduction and Targeted Therapy2023，8，10： | 0 |
| 16 | Study on Formaldehyde Gas Sensor Based on SnO_2 with La_2O_3-ZnO Doping显示文摘SnO_2 nanpowder was prepared by sol-gel method.The SnO_2 based formaldehyde sensor with the doping of La_2O_3 (5wt%)-ZnO(3wt%) was fabricated.The range of the detecting concentration for formaldehyde is from 10μg/g to 300μg/g at 140℃.The sensitivity (S=R_0/R_g) to 10μg/g formaldehyde is 2 and to 300μg/g formaldehyde is 16.The 0.4 nm molecule-sifter layer was coated on the surface of SnO_2 material,the result shows that the selectivity of the formaldehyde sensor is improved. The La_2O_3-ZnO doped SnO_2 sensor shows better stability during 60 days testing. | Baofu Quan Fengmin Liu Ruzheng Liu Lihua Chen Yuehua He Biao Wang | 2006 | 稀有金属材料与工程2006，35，A03： | 0 |
| 17 | Soil nitrogen availability intensifies negative density-dependent effects in a subtropical forest显示文摘负密度制约在维持森林群落物种多样性方面起重要作用。然而,在不同的非生物条件下密度制约效应的强度和方向有可能发生改变。理论预测密度制约效应随土壤可利用氮浓度上升而增强,但仍有待实验结果的验证。本研究基于黑石顶常绿阔叶林群落长达10年的幼苗动态调查数据,以18个常见树种的新生幼苗为研究对象,分析邻体密度制约作用如何在不同环境梯度下变化。通过收集上述目标种中的5个树种的野外幼苗进行根系损伤观察实验,研究在不同可利用氮环境中,土壤病原菌驱动的负密度制约效应是否存在差异。幼苗动态分析结果表明,负密度制约作用的强度随土壤可利用氮浓度的上升而增强。同种幼苗密度在土壤可利用氮浓度低的生境中表现为中性或正密度依赖效应,在土壤可利用氮浓度高的生境中则表现为负密度制约效应。根系损伤观察实验中,在土壤可利用氮浓度高的情况下,5个目标物种中有3个物种表现出更强的负密度制约作用,与幼苗动态分析的结果一致。此外,物种丰富度在土壤可利用氮浓度高的环境中比在浓度低的环境中更高。上述结果表明,在土壤可利用氮浓度高的环境中,更强的土壤病害加剧了负密度制约作用。我们的研究结果强调了负密度制约研究中考虑背景环境的重要性。 | Fengmin Huang Minxia Liang Yi Zheng Xubing Liu Yuxin Chen Wenbin Li Shan Luo Shixiao Yu | 2020 | Journal of Plant Ecology2020，13，3： | 0 |
| 18 | Assessing heavy metal pollution and potential ecological risk of tea plantation soils显示文摘Accumulation of heavy metals in agricultural soils tends to increase crop uptake of heavy metals,and can adversely impact human health through food chains.This study assessed the heavy metal pollution status and the potential ecological risk of tea plantation soils in southern Shaanxi Province,China.A total of 330 topsoil samples were collected to analyze the concentrations of seven heavy metals(Pb,Zn,Cu,Cr,Hg,As and Cd)and the pH level.The Hakanson potential ecological risk index was used based on the background levels of soil heavy metals in Shaanxi.Results showed that the averaged concentrations of soil Pb,Zn,Cu,Cr,Hg,As,and Cd were 10.0,87.6,16.4,12.4,0.2,6.9 and 0.1 mg/kg,respectively.Cd and Hg concentrations exceeded level II of China’s Soil Environment Quality Standard(GB 15618-2009)in 9.3%and 7.0%of the total samples,respectively.The coefficient of variation ranged from 29.2%to 52.2%for different elements,and was 49.3%for Cd and 48.6%for Hg.The averaged comprehensive potential ecological risk index was 95.4,and the overall potential ecological risk was low,with 82.4%of the total samples at a low level of potential ecological risk.Cd and Hg contributed most to the potential ecological risk(35.5%and 46.5%,respectively),and the risks associated with other elements were relatively minor.This study suggested that soil Cd and Hg pollution should be controlled to ensure the safe production of tea in the study area. | Zuoping Zhao Sha Yan Min Duan Jing Fu Qi Wang Zhifeng Liu Fengmin Song Bo Tang Chen Li Gongwei Qin Yanan Tong | 2019 | International Journal of Agricultural and Biological Engineering2019，12，6： | 0 |
| 19 | Use of serum Golgi protein 73 for screening chronic hepatitis B virus infection patients needing antiviral therapy in the community显示文摘Chronic hepatitis B virus (HBV) infection is a major global public health problem. Approximately 887,000 people die of HBV infection-related diseases annually, with cirrhosis and hepatocellular carcinoma (HCC) being the principal causes of mortality.[1] Timely antiviral therapy greatly reduces the risks of cirrhosis and HCC. However, unfortunately, of those patients who are eligible for antiviral treatment, only 25% of patients in clinic settings and 12% of those in community settings obtain timely antiviral therapy.[2] Therefore, reliable means of identifying patients with chronic HBV infection that require antiviral therapy are necessary, particularly for use in the community. | Jinwei Duan Xiajie Wen Huai Wang Weixin Chen Pei Gao Qianli Yuan Han Zheng Yanna Liu Jiang Wu Jie Wang Mingjie Yao Fengmin Lu | 2022 | Chinese Medical Journal2022，135，22： | 0 |
| 20 | High-power distributed feedback lasers based on InP corrugated sidewalls atλ~2μm显示文摘We report a high-power single-mode InP-based 2μm distributed feedback(DFB)laser with a second-order buried grating and corrugated sidewalls.A second-order semiconductor grating is used for in-plane feedback and vertical out-coupling.The corrugated sidewalls are used to eliminate higher-order transverse modes.For the DFB laser with a 2 mm long cavity and 15μm wide ridge,the maximum continuous-wave edge-emitting and surface-emitting single-mode powers at 300 K are up to 81 and 42 m W,respectively.A single-lobed far-field radiation pattern with a low divergence angle of approximately 8.6°is achieved by a device with a ridge width of 15μm.The single-longitudinal-mode emission wavelength of the fabricated laser can be adjusted from2003.8 nm at 288 K to 2006.9 nm at 313 K without any mode hopping.Robust single-mode emission with a side-mode suppression ratio of 30 dB is achieved under all injection currents and temperature conditions. | YONGQIANG SUN YUNFEI XU JINCHUAN ZHANG FENGMIN CHEN JUNQI LIU SHUMAN LIU QUANYONG LU NING ZHUO LIJUN WANG FENGQI LIU SHENQIANG ZHAI | 2023 | Photonics Research2023，11，8： | 0 |
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