|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Removal of nonimpacted third molars alters the periodontal condition of their neighbors clinically, immunologically, and microbiologically显示文摘Considering the adverse effects of nonimpacted third molars(N-M3s)on the periodontal health of adjacent second molars(M2s),the removal of N-M3s may be beneficial to the periodontal health of their neighbors.This study aimed to investigate the clinical,immunological,and microbiological changes of the periodontal condition around M2s following removal of neighboring N-M3s across a 6-month period.Subjects with at least one quadrant containing an intact first molar(M1),M2,and N-M3 were screened and those who met the inclusion criteria and decided to receive N-M3 extraction were recruited in the following investigation.M2 periodontal condition was interrogated before M3 extraction(baseline)and at 3 and 6 months postoperatively.Improvements in clinical periodontal indexes of M2s in response to their adjacent N-M3 removal,along with changes in inflammatory biomarkers among gingival crevicular fluid(GCF)and the composition of subgingival plaque collected from the distal sites of the M2s of the targeted quadrant were parallelly analyzed.Complete data of 26 tooth extraction patients across the follow-up period were successfully obtained and subsequently applied for statistical analysis.Compared to the baseline,the periodontal condition of M2s was significantly changed 6 months after N-M3 removal;specifically,the probing depth of M2s significantly reduced(P<0.001),the matrix metalloproteinase(MMP)-8 concentration involved in GCF significantly decreased(P=0.025),and the abundance of the pathogenic genera unidentified Prevotellaceae and Streptococcus significantly decreased(P<0.001 and P=0.009,respectively).We concluded that N-M3 removal was associated with superior clinical indexes,decreased GCF inflammatory biomarkers,and reduced pathogenic microbiome distribution within the subgingival plaque.Although the retention or removal of N-M3s continues to be controversial,our findings provide additional evidence that medical decisions should be made as early as possible or at least before the neighboring teeth are irretrievably damaged. | Yi Tian Lijuan Sun Honglei Qu Yang Yang Faming Chen | 2021 | International Journal of Oral Science2021，13，1： | 3 |
| 2 | Experimental and numerical study on instability structure of the supersonic mixing layer(M_c = 0.5)显示文摘The parameters of instability wave of supersonic mixing layer(Mc=0.5,M1=3.5/M2=1.4) are measured by flow visualization and calculated by means of two-dimensional direct numerical simulaitons of the compressible Navier-Stokes equations.In both cases of the mixing layer with harmonic disturbance or not,the comparative results indicate that the wavelength of the two-dimensional wave is equal to the vortex spacing in the streamwise direction because the difference between them is less than 1%.However,the measured convective velocity of the large-scale structure deviates from the theoretical isentropic prediction about 10%.Here the measured value confirms that Mc,2 | YANG WuBing ZHUANG FengGan SHEN Qing GUAN FaMing WANG Qiang YI ShiHe ZHAO YuXin HE Lin TIAN LiFeng | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，10： | 2 |
| 3 | Prussian Blue acts as a mediator in a reagentless eytokinin biosensor 显示文摘 | Maria Kowalska Faming Tian Mdria Smehilova Petr Galuszka Ivo Frebort Richard Napier Nicholas Dale | 2011 | Analytica China Aaa2011，701，： | 1 |
| 4 | A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair显示文摘The positive regulation of bone-forming osteoblast activity and the negative feedback regulation of osteoclastic activity are equally important in strategies to achieve successful alveolar bone regeneration. Here, a molybdenum(Mo)-containing bioactive glass ceramic scaffold with solid-strut-packed structures(Mo-scaffold) was printed, and its ability to regulate pro-osteogenic and antiosteoclastogenic cellular responses was evaluated in vitro and in vivo. We found that extracts derived from Mo-scaffold(Moextracts) strongly stimulated osteogenic differentiation of bone marrow mesenchymal stem cells and inhibited differentiation of osteoclast progenitors. The identified comodulatory effect was further demonstrated to arise from Mo ions in the Mo-extract,wherein Mo ions suppressed osteoclastic differentiation by scavenging reactive oxygen species(ROS) and inhibiting mitochondrial biogenesis in osteoclasts. Consistent with the in vitro findings, the Mo-scaffold was found to significantly promote osteoblastmediated bone formation and inhibit osteoclast-mediated bone resorption throughout the bone healing process, leading to enhanced bone regeneration. In combination with our previous finding that Mo ions participate in material-mediated immunomodulation, this study offers the new insight that Mo ions facilitate bone repair by comodulating the balance between bone formation and resorption. Our findings suggest that Mo ions are multifunctional cellular modulators that can potentially be used in biomaterial design and bone tissue engineering. | Beimin Tian Xuan Li Jiujiu Zhang Meng Zhang Dian Gan Daokun Deng Lijuan Sun Xiaotao He Chengtie Wu Faming Chen | 2022 | International Journal of Oral Science2022，14，4： | 1 |
| 5 | Environmental selection and evolutionary process jointly shape genomic and functional profiles of mangrove rhizosphere microbiomes显示文摘Mangrove reforestation with introduced species has been an important strategy to restore mangrove ecosystem functioning.However,how such activities affect microbially driven methane(CH4),nitrogen(N),and sulfur(S)cycling of rhizosphere microbiomes remains unclear.To understand the effect of environmental selection and the evolutionary process on microbially driven biogeochemical cycles in native and introduced mangrove rhizospheres,we analyzed key genomic and functional profiles of rhizosphere microbiomes from native and introduced mangrove species by metagenome sequencing technologies.Compared with the native mangrove(Kandelia obovata,KO),the introduced mangrove(Sonneratia apetala,SA)rhizosphere microbiome had significantly(p<0.05)higher average genome size(AGS)(5.8 vs.5.5 Mb),average 16S ribosomal RNA gene copy number(3.5 vs.3.1),relative abundances of mobile genetic elements,and functional diversity in terms of the Shannon index(7.88 vs.7.84)but lower functional potentials involved in CH4 cycling(e.g.,mcrABCDG and pmoABC),N2 fixation(nifHDK),and inorganic S cycling(dsrAB,dsrC,dsrMKJOP,soxB,sqr,and fccAB).Similar results were also observed from the recovered Proteobacterial metagenome-assembled genomes with a higher AGS and distinct functions in the introduced mangrove rhizosphere.Additionally,salinity and ammonium were identified as the main environmental drivers of functional profiles of mangrove rhizosphere microbiomes through deterministic processes.This study advances our understanding of microbially mediated biogeochemical cycling of CH_(4),N,and S in the mangrove rhizosphere and provides novel insights into the influence of environmental selection and evolutionary processes on ecosystem functions,which has important implications for future mangrove reforestation. | Xiaoli Yu Qichao Tu Jihua Liu Yisheng Peng Cheng Wang Fanshu Xiao Yingli Lian Xueqin Yang Ruiwen Hu Huang Yu Lu Qian Daoming Wu Ziying He Longfei Shu Qiang He Yun Tian Faming Wang Shanquan Wang Bo Wu Zhijian Huang Jianguo He Qingyun Yan Zhili He | 2023 | mLife2023，2，3： | 0 |
| 6 | Third molar-related knowledge,attitudes,behaviors,and medical history of 904 Chinese adults:a cross-sectional survey显示文摘This study investigated the perceptions and medical history of third molars(M3s)and assessed the prevalence of visible M3s(V-M3s)among 904 Chinese adults.The enrolled participants were interviewed to complete a structural questionnaire focused on sociodemographic information and their understanding of,attitudes toward,behaviors regarding,and medical history with respect to M3s.In addition,the number of V-M3s in the cohort was determined by oral examination.Logistic regression analysis was performed to explore the association between individuals'sociodemographic characteristics and their perception of M3s or the presence of V-M3s.The Chi-square test was used to compare the actions taken against symptomatic M3s and the corresponding outcomes among different groups divided according to respondents'sociodemographic factors.In total,904 completed questionnaires were gathered and analyzed.Nearly half(43.9%)of the respondents knew nothing about M3s,and only 12.7%provided correct answers to all the questions asked.Male sex,older age,occupation involving physical labor,and no previous dental experience were active factors in unawareness of M3s.Male sex was also significantly associated with the presence of at least one V-M3 and negative behavior about symptomatic M3s.In terms of medical history,192 participants reported having had at least one M3 extracted(438 in total),and 72.6%of the M3s were removed due to the presence of related symptoms or pathologies.In conclusion,the population investigated had a shortage of knowledge about M3s and adopted negative attitudes and actions about M3-related problems. | Honglei QU Yang YANG Yi TIAN Zhibang LI Lijuan SUN Faming CHEN Beimin TIAN | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，10： | 0 |
| 7 | A universal synthesis of N,S,Cl-doped carbon materials directly from dye waste liquid for high performance lithium storage显示文摘The complicated structured dyes produced by the textile industry have become a serious problem in the last few decades,which can be attributed to their stable chemical structures and difficult to degrade.Therefore,in this article,we described a method to fix dye macromolecules by flocculation process and then transform the colloid to N,S,Cl-doped porous carbon materials.This material can effectively improve the capacity and cycle stability of lithium ion batteries,and recycle the dyes in the water.The N,S,Cl-doped porous carbon materials show a superior electrocatalytic performance of 473.5 mAhg^(−1) at the current density of 100 mAg^(−1) after 60 cycles.The present work combines the lithium ion batteries with dyes waste treatment and has a broad prospect for development. | Junshuang Zhou Kuo Wei Lina Tian Zhuoran Hao Ying Bian Yuanzhe Wang Faming Gao | 2021 | Waste Disposal and Sustainable Energy2021，3，2： | 0 |
| 8 | Reconstruction and Dynamics of the Human Intestinal Microbiome Observed In Situ显示文摘The human gut microbiome has primarily been studied through the use of fecal samples,a practice that has generated vital knowledge on the composition and functional capacities of gastrointestinal microbial communities.However,this reliance on fecal materials limits the investigation of microbial dynamics in other locations along the gastrointestinal tract(in situ),and the infrequent availability of fecal samples prevents analysis at finer temporal scales(e.g.,hours).In our study,we utilized colonic transendoscopic enteral tubing,a technology originally developed for fecal microbiota transplantation,to sample the ileocecal microbiome twice daily;metagenomic and metatranscriptomic analyses were then conducted on these samples.A total of 43 ileocecal and 28 urine and fecal samples were collected from five healthy volunteers.The ileocecal and fecal microbiomes,as profiled in the five volunteers,were found to be similar in metagenomic profiling,yet their active genes(metatranscriptome)were found to be highly distinct.Both microbiomes were perturbed after laxative exposure;over time,they exhibited reduced dissimilarity to their pre-treatment state,thereby demonstrating resilience as an innate property of the gut microbiome,although they did not fully recover within our observation time window.Sampling of the ileocecal microbiome during the day and at night revealed the existence of diurnal rhythms in a series of bacterial species and functional pathways,particularly those related to short-chain fatty acid production,such as Propionibacterium acnes and coenzyme A biosynthesis Ⅱ.Autocorrelation analysis and fluctuations decomposition further indicated the significant periodicity of the diurnal oscillations.Metabolomic profiling in the fecal and urine samples mirrored the perturbance and recovery in the gut microbiome,indicating the crucial contribution of the gut microbiome to many key metabolites involved in host health.This study provides novel insights into the human gut microbiome and its inner resilience and diurnal rhythms,as well as the potential consequences of these to the host. | Xiaolin Liu Min Dai Yue Ma Na Zhao Ziyu Wang Ying Yu Yakun Xu Huijie Zhang Liyuan Xiang He Tian Guanghou Shui Faming Zhang Jun Wang | 2022 | Engineering2022，8，8： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员