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| 1 | Research progress in electrospinning engineering for all-solid-state electrolytes of lithium metal batteries显示文摘Owing to safety issue and low energy density of liquid lithium-ion batteries(LIBs),all-solid-state lithium metal batteries(ASLMBs)with unique all-solid-state electrolytes(SEs)have attracted wide attentions.This arises mainly from the advantages of the SEs in the suppression of lithium dendrite growth,long cycle life,and broad working temperature range,showing huge potential applications in electronic devices,electric vehicles,smart grids,and biomedical devices.However,SEs suffer from low lithiumion conductivity and low mechanical integrity,slowing down the development of practical ASLMBs.Nanostructure engineering is of great efficiency in tuning the structure and composition of the SEs with improved lithium-ion conductivity and mechanical integrity.Among various available technologies for nanostructure engineering,electrospinning is a promising technique because of its simple operation,cost-effectiveness,and efficient integration with different components.In this review,we will first give a simple description of the electrospinning process.Then,the use of electrospinning technique in the synthesis of various SEs is summarized,for example,organic nanofibrous matrix,organic/inorganic nanofibrous matrix,and inorganic nanofibrous matrix combined with other components.The current development of the advanced architectures of SEs through electrospinning technology is also presented to provide references and ideas for designing high-performance ASLMBs.Finally,an outlook and further challenges in the preparation of advanced SEs for ASLMBs through electrospinning engineering are given. | Manxi Wang Yaling Wu Min Qiu Xuan Li Chuanping Li Ruiling Li Jiabo He Ganggang Lin Qingrong Qian Zhenhai Wen Xiaoyan Li Ziqiang Wang Qi Chen Qinghua Chen Jinhyuk Lee Yiu-Wing Mai Yuming Chen | 2021 | Journal of Energy Chemistry2021，30，10： | 4 |
| 2 | Electrospinning Engineering Enables High‑Performance Sodium‑Ion Batteries显示文摘As a promising energy storage device,sodium-ion batteries(SIBs)have received continuous attention due to their low-cost and environmental friendliness.However,the sluggish kinetics of Na ion usually makes SIBs hard to realize desirable electrochemical performance when compared to lithium-ion batteries(LIBs).The key to addressing this issue is to build up nanostructured materials which enable fast Na-ion insertion/extraction.One-dimensional(1D)nanocarbons have been considered as both the anode and the matrix to support active materials for SIB electrodes owing to their high electronic conductivity and excellent mechanical property.Because of their large surface areas and short ion/electron difusion path,the synthesized electrodes can show good rate performance and cyclic stability during the charge/discharge processes.Electrospinning is a simple synthetic technology,featuring inexpensiveness,easy operation and scalable production,and has been largely used to fabricate 1D nanostructured composites.In this review,we frst give a simple description of the electrospinning principle and its capability to construct desired nanostructures with diferent compositions.Then,we discuss recent developments of carbon-based hybrids with desired structural and compositional characteristics as the electrodes by electrospinning engineering for SIBs.Finally,we identify future research directions to realize more breakthroughs on electrospun electrodes for SIBs. | Chuanping Li Min Qiu Ruiling Li Xuan Li Manxi Wang Jiabo He Ganggang Lin Liren Xiao Qingrong Qian Qinghua Chen Junxiong Wu Xiaoyan Li Yiu‑Wing Mai Yuming Chen | 2022 | Advanced Fiber Materials2022，4，1： | 1 |
| 3 | Target prediction and activity verification for the antidepressant action of Huangqin(Radix Scutellariae Baicalensis)显示文摘OBJECTIVE:To decipher the antidepressant targets and mechanisms of Huangqin(Radix Scutellariae Baicalensis)(RSB)by a novel computational system based on prediction and experimental verification.METHODS:The putative targets of RSB against depression were identified from Traditional Chinese Medicine Systems Pharmacology(TCMSP)and Drug Bank.Next,protein-protein interaction network of the anti-depression targets of RSB were identified,and differentially expressed genes(DEGs)of depression were mined from the NCBI database.Then,Kyoto Encyclopedia of Genes and Genomes and Gene Ontology were used to analysis the common targets.Finally,the selected pathways and functions were verified by experimentation.RESULTS:Thirty active compounds in RSB were predicted with high confidence by TCMSP and DrugBank,and seventy-one DEGs were identified in the GEO database.Besides,eight core target proteins were screened out by descending order of degree value,including ACHE,IL6,SLC6A4,FOS,SLC6A3,MAOB,DPP4,and JUN.These target genes were further found to be associated with pathways involved in neuronal apoptosis,such as pathways in cancer,Toll-like receptor signaling pathway,and TNF signaling.The cell proliferation assay and wound-healing assay results showed that RSB does not affect PC12 cell proliferation and chemotaxis.Unexpectedly,RSB protected PC12 cells from oxidative stress induced by H2O2 via inhibiting autophagy and apoptosis.We revealed significant changes in mice treated with 400 mg/kg RSB compared with the lipopolysaccharide mice.The possible mechanism for the antidepressive action of RSB is by reducing the expression of LC3-B in CA1 neurons.CONCLUSIONS:Our research partially expounds the mechanism of the antidepressant effect of RSB by the combination of network pharmacology prediction and experimental verification.Furthermore,it is also conducive to the application of Traditional Chinese Medicine within modern medicine. | LI Ganggang LU Ye HE Pei ZHANG Shiyue CHENG Yating ZHANG Shaodan PEI Lin | 2021 | Journal of Traditional Chinese Medicine2021，41，6： | 0 |
| 4 | Research Progress in Lithium-Excess Disordered Rock-Salt Oxides Cathode显示文摘The increasing demand for new energy sources has promoted the improvement of the energy storage capacity of lithium-ion batteries(LIBs)that urged the development of higher energy density cathode materials.The enhancement of the classical cathode in the last 30 years has reached a bottleneck,and then the discovery of the lithium-excess disordered materials has greatly expanded the research space of the cathode materials.Compared with the conventional layered oxides,the lithium-excess disordered rock-salt oxides(LEDRXs)with a more stable structure has higher extractable Li^(+)content,even though the inactive high-valent transition metals(TMs)were needed to compensate for the excess Li,which would reduce the total TM redox content.In addition,oxygen redox provides additional electron capacity for the materials,which also causes O loss and results in the subsequent poor cycle performance.Herein,a series of studies about LEDRXs and their targeted modification measures are summarized,including the prospect of the materials,in order to provide ideas for the design of highperformance LEDRXs.Finally,the new discoveries and outlook on future research directions of LEDRX cathode materials for LIBs with higher energy density are given. | Manxi Wang Xiaochuan Chen Hurong Yao Ganggang Lin Jinhyuk Lee Yuming Chen Qinghua Chen | 2022 | Energy & Environmental Materials2022，5，4： | 0 |
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