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| 1 | Isolation, characterization and functional analysis of a cdc48 homologue from tobacco BY-2 cells显示文摘分裂酵母 Schizosaccharomyces pombe 被用来从可以在房间周期规定起作用的烟草 BY-2 房间识别基因。编码对酵母 CDC48 相应的蛋白质的 cDNA 被孤立,基因被指定为 NtCDC48。cDNA 包含为二个 twical ATPase 模块包括的 808 氨基酸的预言的蛋白质编码的一个开的读物框架(一 245-374 并且一 518-646 ) 。NtCDC48in 烟草 BY-2 房间的 Overexpression 在有丝分裂的索引以及到传播有丝分裂的锭子的形成导致了增加。NtCDC48-GFP 熔化蛋白质还通过 G1 无所不在地被散布到 M 阶段的家他们细胞的本地化与房间周期前进一起定期改变了的潜水艇。这些结果显示 NtCDC48 可以在 BY-2 房间在房间周期的规定起一个重要作用。 | CHEN Zhiling Yu Yi LIU Lina XIA Guixian | 2007 | Progress in Natural Science:Materials International2007，17，2： | 6 |
| 2 | Airborne PCDD/Fs in two e-waste recycling regions after stricter environmental regulations显示文摘Since the 2010 s, the authorities of Guangdong province and local governments have enhanced law enforcement and environmental regulations to abolish open burning, acid washing, and other uncontrolled e-waste recycling activities. In this study, ambient air and indoor dust near different kinds of e-waste recycling processes were collected in Guiyu and Qingyuan to investigate the pollution status of particles and polychlorinated dibenzo-pdioxins and furans(PCDD/Fs) after stricter environmental regulations. PM_(2.5) and PCDD/Fs both showed significantly reduced levels in the two regions compared with the documented data. The congener distribution and principal component analysis results also confirmed the significant differences between the current PCDD/Fs pollution characterizations and the historical ones. The estimated total intake doses via air inhalation and dust ingestion of children in the recycling region of Guiyu ranged from 10 to 32 pg TEQ/(kg·day), which far exceeded the tolerable daily intake(TDI) limit(1–4 pg TEQ/(kg·day). Although the measurements showed a significant reduction of the release of PCDD/Fs, the pollution status was still considered severe in Guiyu town after stricter regulations were implemented. | Manwen Zhang Guixian Feng Wenhua Yin Bing Xie Mingzhong Ren Zhencheng Xu Sukun Zhang Zongwei Cai | 2017 | Journal of Environmental Sciences2017，29，12： | 5 |
| 3 | ZnFe2O4 deposited on BiOCl with exposed (001) and (010) facets for photocatalytic reduction of C02 in cyclohexanol显示文摘 | Guixian Song Xionggang Wu Feng Xin Xiaohong Yin | 2017 | Frontiers of Chemical Science and Engineering2017，11，2： | 5 |
| 4 | Highly biocompatible BSA-MnO_2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy显示文摘More recently, the biomedical applications of MnO_2 in bioanalysis, cell imaging, and drug delivery as a result of their appealing physicochemical properties, have been reported and expanded rapidly. However,research on a near infrared(NIR) photothermal response of MnO_2 was ignored. In this work, we reported a facile, one-pot method to synthesis of bovine serum albumin(BSA)-reduced and stabilized MnO_2 nanoparticles(BSA-MnO_2 NPs) with good aqueous dispersibility and high biocompatibility. And we also showed for the first time that BSA-MnO_2 NPs displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent. | Yuzhen Wang Yujun Song Guixian Zhu Dechen Zhang Xuewu Liu | 2018 | Chinese Chemical Letters2018，29，11： | 5 |
| 5 | Characterization and pilot functional study of a root-specific MYB transcription factor of Arabidopsis显示文摘An MYB transcription factor (AtMYB305) of Arabidopsis was structurally characterized. The biochemical activity of the protein was tested and its in vivo function was preliminarily analyzed. AtMYB305 contains two imperfect repeats (R2, R3) in its DNA binding domain. Gel mobility shift assay demonstrated that GST-AtMYB305 fusion pro-tein bound specifically to the DNA fragment that included a consensus MYB recognition sequence (TAACTG). Overex-pression of AtMYB305 in the fission yeast caused the forma-tion of elongated cells with one condensed nucleus. Semi-quantitative RT-PCR analysis revealed that AtMYB305 was expressed specifically in the roots of Arabidopsis. | Dong Wang Lihong Li Zhiling Chen Guixian Xia | 2002 | Chinese Science Bulletin2002，47，4： | 4 |
| 6 | Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics显示文摘Limited knowledge of cellular and molecular mechanisms underlying hematopoietic stem cell and multipotent progenitor(HSC/MPP)expansion within their native niche has impeded the application of stem cell-based therapies for hematological malignancies.Here,we constructed a spatiotemporal transcriptome map of mouse fetal liver(FL)as a platform for hypothesis generation and subsequent experimental validation of novel regulatory mechanisms.Single-cell transcriptomics revealed three transcriptionally heterogeneous HSC/MPP subsets,among which a CD93-enriched subset exhibited enhanced stem cell properties.Moreover,by employing integrative analysis of single-cell and spatial transcriptomics,we identified novel HSC/MPP‘pocket-like’units(HSC PLUS),composed of niche cells(hepatoblasts,stromal cells,endothelial cells,and macrophages)and enriched with growth factors.Unexpectedly,macrophages showed an 11-fold enrichment in the HSC PLUS.Functionally,macrophage-HSC/MPP co-culture assay and candidate molecule testing,respectively,validated the supportive role of macrophages and growth factors(MDK,PTN,and IGFBP5)in HSC/MPP expansion.Finally,cross-species analysis and functional validation showed conserved cell-cell interactions and expansion mechanisms but divergent transcriptome signatures between mouse and human FL HSCs/MPPs.Taken together,these results provide an essential resource for understanding HSC/MPP development in FL,and novel insight into functional HSC/MPP expansion ex vivo. | Suwei Gao Qiang Shi Yifan Zhang Guixian Liang Zhixin Kang Baofeng Huang Dongyuan Ma Lu Wang Jianwei Jiao Xiangdong Fang Cheng-Ran Xu Longqi Liu Xun Xu Berthold Gottgens Cheng Li Feng Liu | 2022 | Cell Research2022，32，1： | 4 |
| 7 | The velocity structure of the Yinggehai Basin and its hydrocarbon implication显示文摘Two profiles of refraction and wide_angle reflection were completed in the Yinggehai Basin using ocean bottom hydrophones (OBHs) as receiver. These profiles reveal a low velocity layer (LVL) to the west of No. 1 Fault in the basin, with velocity of 3.0-3.5 km/s. Its upper interface lies at 3.5 km below the sea bottom at the NE end of the profiles, and deepens southwestward to 4 6 km near the axis of the basin. It coincides with the top of a gas_bearing, high_pressure layer defined by well logging. This suggests that the LVL is a layer of less_compacted and gas_charged sediments. The lower interface of the LVL is about 9 km in depth. Sediments above the LVL have velocity varying from 2 0 to 4 1 km/s. The acoustic basement is found only east of No. 1 Fault, with velocity of 5 8-6 2 km/s. A NNW_SSE_running OBH seismic profile across the Xisha Trough was completed on the same cruise. Moho and other deep interfaces are clearly visible in the profile. | Kanyuan Xia Di Zhou Daquan Su E. Flueh Sanyu Ye Hanyi He Weidong Chen Yuhong Xie Guixian Wang Saijun Liu et al. | 1998 | Chinese Science Bulletin1998，43，24： | 3 |
| 8 | Sino-MONICA Project: A Collaborative Study on Trends and Determinants in Cardiovascular Diseases in China, Part I: Morbidity and Mortality Monitoring显示文摘 | Zhaosu Wu Chonghua Yao Dong Zhao Guixian Wu Wei Wang Jing Liu Zhechun Zeng Yingkai Wu | 2001 | Circulation: Journal of the American Heart Association2001，，1： | 3 |
| 9 | Expression of a cotton profilin gene GhPFN1 is associated with fiber cell elongation显示文摘Profilin is an important actin-binding protein involved in regulating the organization of actin filaments. A cotton profilin gene (GhPFN1) that shares 71% identity to profilin1 of Arabidopsis in its amino acid sequence was isolated. Semi-quantitative RT-PCR showed that GhPFN1 was expressed preferentially in the developing cotton fibers and reached the highest level at the fast elongation stage. The function of GhPFN1 in vivo was analyzed using the S. pombe system, and results suggested that GhPFN1 plays a role in fiber cell elongation. | LI Lihong, WANG Haiyun, LI Yan and XIA Guixian(Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China) | 2002 | Progress in Natural Science:Materials International2002，12，10： | 3 |
| 10 | Rheological Behavior for Polymer Melts and Concentrated Solutions——Part Ⅶ: A Quantitative Verification for the Molecular Theory of Non-linear Viscoelasticity with Entanglement Constraints in Polymer Melts显示文摘Based on the molecular theory of non-linear viscoelasticity with constrained entanglements in polymer melts, the material functions in simple shear flow were formulated, the theoretical relations between and shear rate (), and topologically constrained dimension number and a were derived. Linear viscoelastic parameters and and topologically constrained dimension number and as a function of the primary molecular weight, molecular weight between entanglements and the entanglement sites sequence distribution in polymer chain were determined. A new method for determination of viscoelastic parameters G and topologically constrained dimension number a and and molecular weight and from the shear flow measurements was proposed. It was used to determine those parameters and structures of HDPE, making a good agreement between these values and those obtained by other methods. The agreement affords a quantitative verification for the molecular theory of nonlinear viscoelasticity with constrained entanglement in polymer melts. | Mingshi SONG, Chen ZHANG and Guixian HU Research Institute of Polymeric Materials, Beijing University of Chemical Technology, Beijing 100029, China E-mail: wangzhchen@sina.com | 2001 | Journal of Materials Science & Technology2001，17，3： | 2 |
| 11 | Fabrication and characterization of microfibrillated cellulose and collagen composite films显示文摘Microfibrillated cellulose(MFC)-collagen composite films were prepared with a dispersion of acid swollen collagen fibers and carboxylated MFC at different ratios in an alkaline homogenous system.The surface topographic results obtained from SEM analyses indicated that the MFC entangled uniformly with collagen in the film and formed a closely interwoven network to reinforce the film structure.However,the MFC addition decreased the smoothness and light transparency of the films due to the aggregation of MFC.Compared to the film prepared with pure collagen,the hybrid composite film showed a higher strength and Young’s modulus but lower elongation.The swelling of the composite film in water increased with the increase of the MFC ratio in the film matrix.DSC and TG analyses demonstrated that adding MFC to collagen benefited the thermal stability of the films,due to the conformational and crystal changes in the MFC/collagen structure indicated by the FT-IR and XRD results.The MFC/collagen composite film can potentially be used as an edible material in the food and packaging industry,in particular for meat products. | Wenhang Wang Yabin Wang Yanan Wang Xiaowei Zhang Xiao Wang Guixian Gao | 2016 | Journal of Bioresources and Bioproducts2016，1，4： | 2 |
| 12 | Degradation of tartrazine by peroxymonosulfate through magnetic Fe_(2)O_(3)/Mn_(2)O_(3) composites activation显示文摘In this study,Fe_(2)O_(3)/Mn_(2)O_(3) composite was synthesized by a facile two-step technique,and several methods were carried out to characterize it.Then,the decomposition experiments of tartrazine(TTZ),a kind of refractory o rganic pollutant,were conducted under various enviro nmental condition to detect the catalyst performance,such as reaction system,the dosage of catalyst,peroxymonosulfate(PMS)concentration,initial pH,different natural water substances.The results exhibited that Fe_(2)O_(3)/Mn_(2)O_(3) composite with the mole rate 2:3 had the best PMS activation performance and the removal efficiency was 97.3%within 30 min.Besides,the optimum degradation conditions of TTZ we re also discussed,that is catalyst dosage(0.6 g/L),PMS concentration(0.8 g/L)and the initial pH 11.In addition,proved by the natural water substances adding experiments,HPO_(4)^(2)-,HCO_(3)^-,NO_(3)^-and NOM(nature organic matter)could slow down the experiments progressing,but Cl^-could boost it.Then inhibitor experiments indicated both the HO^·and SO_(4)^·-played a vital role in the experiments.Reusability and ions leaching experiments as well as the used catalyst physical characte rization images exhibited the excellent stability and cyclicity of the Fe_(2)O_(3)/Mn_(2)O_(3) composite.Finally,based on the XPS(X-ray photoelectro n spectro scopy)and the experiments results,the possible mechanism of TTZ degradation was proposed.This system might provide a novel thought for the decomposition of refractory organic pollutant and had potential in promotion of actual sewage treatment technology. | Gong Chen Li-Chao Nengzi Yingjie Gao Guixian Zhu Jianfeng Gou Xiuwen Cheng | 2020 | Chinese Chemical Letters2020，31，10： | 2 |
| 13 | BED FORMS AND RESISTANCE PROPERTIES OF LIGHT-WEIGHT BED MATERIAL显示文摘Based on experimental results from a large tilting flume, the characteristics and de- veloping processes of bed forms of plastic particles during scouring and deposition are systematically studied. The relationships of the occurence, development and disappearence of sand waves with the flow conditions are presented. Various statistical characteristics of sand waves with different sizes and the corresponding resistance properties of different bed forms of plastic particles are obtained. These results have filled in the gaps in bed forms and resistance properties of light sediment particles. It also serves as useful reference in the design of river model tests. | WANG Guixian ,WANG Xingkui,GUO Jiachao Professor, Sediment Research Laboratory, Dept. of Hydraulic Engineering, Tsinghua University, Beijing 100084, China. Associate Professor, Dept. of Hydraulic Engineering, Tsinghua University. Assistant, Dept. of Hydraulic Engineering, Tsinghua University. | 1993 | International Journal of Sediment Research1993，8，3： | 2 |
| 14 | Radio frequency identification (RFID) in China:opportunities and challenges显示文摘 | LAI Fujun HUTCHINSON Joe ZHANG Guixian | 2005 | International Journal of Retail & Distribution Management2005，33，12： | 1 |
| 15 | Research on meshing theory of noninvolute beveloid gears 显示文摘 | LI GUIXIAN WEN JIANMIN | 2003 | Journal of Harbin Institate of Technology2003，10，2： | 1 |
| 16 | A large insert Thellungiella halophila BIBAC library for genomics and identification of stress tolerance genes显示文摘 | Weiquan Wang Yaorong Wu Yin Li Jiaying Xie Zhonghui Zhang Zhiyong Deng Yiyue Zhang Cuiping Yang Jianbin Lai Huawei Zhang Hongyan Bao Sanyuan Tang Chengwei Yang Peng Gao Guixian Xia Huishan Guo Qi Xie | 2010 | Plant Molecular Biology (-)2010，，1： | 1 |
| 17 | Sino-MONICA Project: A Collaborative Study on Trends and Determinants in Cardiovascular Diseases in China, Part I: Morbidity and Mortality Monitoring显示文摘 | Zhaosu Wu Chonghua Yao Dong Zhao Guixian Wu Wei Wang Jing Liu Zhechun Zeng Yingkai Wu | 2001 | Circulation: Journal of the American Heart Association2001，，1： | 1 |
| 18 | Study of Catalytic Hydrogenation of 1, 4-Benzenediol over Ru/HY catalys显示文摘 | Li Guixian Dong Peng Wang Xiaorui | 2011 | Journal of Molecular Catalysis (China)2011，15，4： | 1 |
| 19 | A Kind of New Tracking Algorithm of Movement Object 显示文摘 | Pan Feng Wang Xuanyin Xiang Guixian | 2005 | Optics Engineering2005，32，1： | 1 |
| 20 | Electronic nose tech-nique potential monitoring mandarin mandarin maturity 显示文摘 | Gomez A H Wang Jun Hu Guixian | 2006 | Sensorsand Actuators B:Chemical2006，113，1： | 1 |
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