|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Defects in Mesenchymal Stem Cell Self-Renewal and Cell Fate Determination Lead to an Osteopenic Phenotype in Bmi-1 Null Mice(摘要)显示文摘 | Zhang, HW Ding, J Jin, JL Guo, J Liu, JN Karaplis, A Goltzman, D Miao, DS | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 13 |
| 2 | 术中应用荧光素钠有利于胶质母细胞瘤浸润边缘的手术切除(英文)显示文摘Objective Extent of resection is an important prognostic factor in patients undergoing surgery for glioblastoma( GBM).Recent evidence suggests that intravenously administered fluorescein sodium associates with tumor tissue,facilitating safe maximal resection of GBM. In this study,the authors evaluate the safety and utility of intraoperative fluorescein guidance for the prediction of histopathological alteration both in the contrast-enhancing( CE) regions,where this relationship has been established,and into the nonCE( NCE),diffusely infiltrated margins. Methods Thirty-two patients received fluorescein sodium( 3 mg/kg) intravenously prior to resection. Fluorescence was intraoperatively visualized using a Zeiss Pentero surgical microscope equipped with a YELLOW 560 filter.Stereotactically localized biopsy specimens were acquired from CE and NCE regions based on preoperative MRI in conjunction with neuronavigation. The fluorescence intensity of these specimens was subjectively classified in real time with subsequent quantitative image analysis,histopathological evaluation of localized biopsy specimens,and radiological volumetric assessment of the extent of resection.Results Bright fluorescence was observed in all GBMs and localized to the CE regions and portions of the NCE margins of the tumors,thus serving as a visual guide during resection. Gross-total resection( GTR) was achieved in 84% of the patients with an average resected volume of 95%,and this rate was higher among patients for whom GTR was the surgical goal( GTR achieved in 93. 1% of patients,average resected volume of 99. 7%). Intraoperative fluorescein staining correlated with histopathological alteration in both CE and NCE regions,with positive predictive values by subjective fluorescence evaluation greater than 96% in NCE regions. Conclusions Intraoperative administration of fluorescein provides an easily visualized marker for glioma pathology in both CE and NCE regions of GBM. These findingssupport the use of fluorescein as a microsurgical adjunct for guiding GBM resection to facilitate safe maximal removal. | Neira JA Ung TH Sims J Malone HR Chow DS Samanamud JL Zanazzi GJ Guo X Bowden SG Zhao B Sheth SA McKhann GM 2nd Sisti MB Canoll P D'Amico RS Bruce JN | 2016 | 中华神经外科疾病研究杂志2016，15，5： | 2 |
| 3 | Beaded silicon carbide nanochains via carbothermal reduction of carbonaceous silica xerogel显示文摘 | Hao Y-J Wagner JB Su DS Jin G-Q Guo X-Y | 2006 | Nanotechnology2006，17，12： | 1 |
| 4 | Investigating the effects of climate variations on bacillary dysentery incidence in Northeast China using ridge regression and hierarchical cluster analysis 显示文摘 | HUANG DS GUAN P GUO JQ | 2008 | BMC InfectDis2008，8，： | 1 |
| 5 | Peripheral T cells overexpress MIP-lalpha to enhance its transendothelial migration in Alzheimer's disease.显示文摘 | Man SM Ma YR Shang DS Zhao WD Li B Guo DW Fang WG Zhu L Chert YH | 2006 | 中国生物学文摘2006，20，9： | 1 |
| 6 | Numerical simulation of heatand mass transfer in plate-type evaporative condenser显示文摘 | Guo CQ Zhu DS Jiang X | 2009 | Journal of South China University of Technology2009，37，3： | 1 |
| 7 | The association between arsenic exposure from drinking water and cerebrovascular disease mortality in Taiwan显示文摘 | Cheng TJ Ke DS Guo HR | 2010 | Water Research2010，44，19： | 1 |
| 8 | The association between arse- nic exposure from drinking water and cerebrovascular dis- ease mortality in Taiwan 显示文摘 | Cheng TJ Ke DS Guo HR | 2010 | Water Res2010，44，19： | 1 |
| 9 | DrugBank; a knowl edgebase for drugs, drug actions and drug targets显示文摘 | Wishart DS Knox C Guo AC | 2008 | Nucleic Acids Research2008，36，： | 1 |
| 10 | DrugBank: a comprehensive resource for in silico drug discovery and exploration 显示文摘 | Wishart DS Knox C Guo AC | 2006 | Nucleic Acids Research2006，34，： | 1 |
| 11 | Axin and GSK3- control Smad3 protein stability and modulate TOF-signa- ling显示文摘 | Guo X Ramirez A Waddell DS | 2008 | Genes Dev2008，22，1： | 1 |
| 12 | Prevalence of primary open angle glaucoma in a rural adult Chi- nese population:the Handan eye study 显示文摘 | Liang YB Friedman DS Zhou Q Yang X Sun LP Guo LX | 2011 | Invest Ophthalmol Vis Sci2011，52，11： | 1 |
| 13 | Prevalence and characteristics of primary angle-closure diseases in a rural adult Chinese population: the Handan eye study 显示文摘 | Liang YB Friedman DS Zhou Q Yang XH Sun LP Guo L | 2011 | Invest Ophthalmol Vis Sci2011，52，12： | 1 |
| 14 | DrugBank: a knowledge base for drugs, drug actions and drug targets 显示文摘 | Wishart DS Knox C Guo AC | 2008 | Nucleic Acids Res2008，36，： | 1 |
| 15 | A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor 显示文摘 | Taylor RM Pili R Guo Y Long PV Haney JA Pauly RR Grant DS Martin GR | 1992 | Lab Invest1992，67，4： | 1 |
| 16 | Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury显示文摘 | Qu WS Tian DS Guo ZB | 2012 | J Neuroinflammation2012，23，9： | 1 |
| 17 | Roles and significance of LRIG1gene in human astrocytomas显示文摘 | Yi W Fei Y Guo DS | 2005 | Chinese German J ClinOncol2005，4，： | 1 |
| 18 | Assembly of theviroplasm by viral non-structural protein PnslO isessential for persistent infection of rice ragged stunt virusin its insect vector显示文摘 | Jia DS Guo NM Chen HY | 2012 | The Journal of General Virology2012，93，： | 1 |
| 19 | DrugBank:a comprehensive resource for in silico drug discovery and exploration显示文摘 | Wishart DS Knox C Guo AC | | 0，，01： | 1 |
| 20 | Expression of leucine-rich re- peats and immunoglobulin-like domains (LRIG) proteins in human astrocytomas 显示文摘 | Yi W Ye F Guo DS | 2005 | Chinese-German J Clin Oncol2005，4，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员