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| 1 | Study on Ni/C catalysts for vapor phase carbonylation of ethanol显示文摘激活支持碳的 Ni 催化剂让乙醇的蒸汽阶段 carbonylation 当倡导者被调查,面对乙醇碘化物支撑离子的酸。在最佳反应条件下面,当时,碳一氧化物和乙醇的变换被测量分别地,是 81.4% 和 98.4% 选择为支撑离子的酸被发现是 98.65% 。催化剂在溪流上的 48 h 以内是稳定的。XRD 和 XPS 方法被用来描绘结构和新鲜、测试的催化剂的表面性质。描述结果显示镍粒子和催化剂表面上的镍碘化物的形成的聚集应该为催化剂的释放负责。 | Qing Zhang Huifang Wang Guosong Sun Kelin Huang Weiping Fang Yiquan Yang | 2008 | Journal of Natural Gas Chemistry2008，17，4： | 3 |
| 2 | Multiplex genome editing using a dCas9-cytidine deaminase fusion in Streptomyces显示文摘CRISPR/Cas-mediated genome editing has greatly facilitated the study of gene function in Streptomyces. However, it could not be efficiently employed in streptomycetes with low homologous recombination(HR) ability. Here, a deaminase-assisted base editor d Cas9-CDA-ULstr was developed in Streptomyces, which comprises the nuclease-deficient Cas9(dCas9), the cytidine deaminase from Petromyzon marinus(PmCDA1), the uracil DNA glycosylase inhibitor(UGI) and the protein degradation tag(LVA tag). Using d Cas9-CDA-ULstr , we achieved single-, double-and triple-point mutations(cytosine-to-thymine substitutions)at target sites in Streptomyces coelicolor with efficiency up to 100%, 60% and 20%, respectively. This base editor was also demonstrated to be highly efficient for base editing in the industrial strain, Streptomyces rapamycinicus, which produces the immunosuppressive agent rapamycin. Compared with base editors derived from the cytidine deaminase rAPOBEC1, the PmCDA1-assisted base editor dCas9-CDA-ULstr could edit cytosines preceded by guanosines with high efficiency, which is a great advantage for editing Streptomyces genomes(with high GC content). Collectively, the base editor dCas9-CDA-ULstr could be employed for efficient multiplex genome editing in Streptomyces. Since the d Cas9-CDA-ULstr -based genome editing is independent of HR-mediated DNA repair, we believe this technology will greatly facilitate functional genome research and metabolic engineering in Streptomyces strains with weak HR ability. | Yawei Zhao Jinzhong Tian Guosong Zheng Jun Chen Chuanwen Sun Zhongyi Yang Andrei A.Zimin Weihong Jiang Zixin Deng Zhijun Wang Yinhua Lu | 2020 | Science China(Life Sciences)2020，63，7： | 2 |
| 3 | Statistical characteristics and mechanisms of mesoscale eddies in the North Indian Ocean显示文摘The statistical characteristics and mechanisms of mesoscale eddies in the North Indian Ocean are investigated by adopting multi-sensor satellite data from 1993 to 2019.In the Arabian Sea(AS),seasonal variation of eddy characteristics is remarkable,while the intraseasonal variability caused by planetary waves is crucial in the Bay of Bengal(BOB).Seasonal variation of the eddy kinetic energy(EKE)is distinct along the west boundary of AS,especially in the Somali Current region.In the BOB,larger EKE occurs at the northwest basin from March to May,to the east of Sri Lanka from June to September,and along the east coast of India from November to December.The wind stress work(WW)is further studied to figure out the direct influence of wind forcing on EKE.The WW exerts positive effects on EKE along the west boundary of AS and in the south of India/Sri Lanka during the two monsoon seasons.Besides,the WW also has impact on EKE along the east coast of India in November and December.Eventually,we investigate the characteristics and the driving mechanisms of long lifespan eddies.In the AS,long lifespan anti-cyclonic eddies(AEs)mainly generate in the Socotra,the West Indian Coastal Current and the East Arabian Current regions,while cyclonic eddies(CEs)are concentrated in the northwest region.In the BOB,long lifespan AEs mostly form near the west of Myanmar,while CEs are accumulated at the north and northwest basin.The instabilities caused by Rossby waves,coastal Kelvin waves,seasonal currents,together with wind stress forcing exert enormous efforts on the generation and evolution of these eddies. | Chunjian Sun Xidong Wang Anmin Zhang Lianxin Zhang Caixia Shao Guosong Wang | 2022 | Acta Oceanologica Sinica2022，41，5： | 1 |
| 4 | Influence of interlayers on corrosion resistance of diamond-like carbon coating on magnesium alloy 显示文摘 | Wu Guosong Sun Lili Dai Wei | 2010 | Surf Coat Techn2010，204，： | 1 |
| 5 | Telomere-to-telomere pear (Pyrus pyrifolia) reference genome reveals segmental and whole genome duplication driving genome evolution显示文摘Previously released pear genomes contain a plethora of gaps and unanchored genetic regions.Here,we report a telomere-to-telomere(T2T)gap-free genome for the red-skinned pear,‘Yunhong No.1’(YH1;Pyrus pyrifolia),which is mainly cultivated in Yunnan Province(southwest China),the pear’s primary region of origin.The YH1 genome is 501.20 Mb long with a contig N50 length of 29.26 Mb.All 17 chromosomes were assembled to the T2T level with 34 characterized telomeres.The 17 centromeres were predicted and mainly consist of centromeric-specific monomers(CEN198)and long terminal repeat(LTR)Gypsy elements(≥74.73%).By filling all unclosed gaps,the integrity of YH1 is markedly improved over previous P.pyrifolia genomes(‘Cuiguan’and‘Nijisseiki’).A total of 1531 segmental duplication(SD)driven duplicated genes were identified and enriched in stress response pathways.Intrachromosomal SDs drove the expansion of disease resistance genes,suggesting the potential of SDs in adaptive pear evolution.A large proportion of duplicated gene pairs exhibit dosage effects or sub-/neo-functionalization,whichmay affect agronomic traits like stone cell content,sugar content,and fruit skin russet.Furthermore,as core regulators of anthocyanin biosynthesis,we found that MYB10 and MYB114 underwent various gene duplication events.Multiple copies of MYB10 and MYB114 displayed obvious dosage effects,indicating role differentiation in the formation of red-skinned pear fruit.In summary,the T2T gap-free pear genome provides invaluable resources for genome evolution and functional genomics. | Manyi Sun Chenjie Yao Qun Shu Yingyun He Guosong Chen Guangyan Yang Shaozhuo Xu Yueyuan Liu Zhaolong Xue Jun Wu | 2023 | Horticulture Research2023，10，11： | 0 |
| 6 | The glyco-regioisomerism effect on dynamic interactions between glycopolymers with galactose pendants and benzoxaborole-containing polymer显示文摘This work investigated the effect of glyco-regioisomerism of glycopolymers on their dynamic interaction with benzoxaborole-containing polymers. Two kinds of glycopolymers, P-1-Gal and P-6-Gal, i.e. galactoside pendant group linked to the identical main chain through its anomeric(C1) and C6-hydroxyl group position, respectively, were studied. We found that P-6-Gal showed stronger binding strength to the PNIPAM-co-PBOB polymer than P-1-Gal did, which controlled the macroscopic property of the resultant hydrogels at a molecular level. | Pengfei Sun Sichao Tian Mingchang Lin Guosong Chen | 2018 | Science China Chemistry2018，61，1： | 0 |
| 7 | One-dimensional Ag2S/ZnS/ZnO nanorod array films for photocathodic protection for 304 stainless steel显示文摘Highly ordered Ag2 S/ZnS/ZnO nanorod array film photoanodes were prepared on a Ti substrate for photocathodic cathodic protection.The results indicated that the photoresponse range of the Ag2S/ZnS/ZnO composite film was extended compared to those of the ZnO and ZnS/ZnO films,indicating its higher light absorption capacity.When the Ag2S/ZnS/ZnO composite film served as a photoanode,the film can provide the best effective photocathodic protection for 304 stainless steel in a 3.5 wt%NaCl solution under white light illumination compared to the ZnO and ZnS/ZnO films.Additionally,in comparison to pure ZnO film,the photocurrent for the ZnS/ZnO film remained the same without noticeable fluctuation after illumination for 1 h,indicating that the ZnS functionalization improved the stability by overcoming the photocorrosion effect of the ZnO photoanode under light irradiation. | Na Wei Yuan Lin Zhenkui Li Wenxia Sun Guosong Zhang Mingliang Wang Hongzhi Cui | 2020 | Journal of Materials Science & Technology2020，42，7： | 0 |
| 8 | Achieving gradient heterogeneous structure in Mg alloy for excellent strength-ductility synergy显示文摘Most metals including Mg alloys have a longstanding dilemma of strength-ductility trade-off,which is hindering their wider applications.In this study,we propose a gradient heterogeneous grain(GHG)structure for evading this trade-off dilemma and ultrasonic severe surface rolling is attempted to construct this novel structure in ZE41 Mg alloy.Here,the GHG structure combine the benefits of gradient structure and heterogeneous grain structure and introduce large microstructural heterogeneities.Compared to the coarse-grain and heterogeneous-grain structured alloys,the GHG structured one exhibits dramatical enhancement in strength,ductility,and strain hardening capability.To the best of our knowledge,its strength becomes much higher than that of common ZE41 Mg alloys at no reduction in ductility.These unique mechanical properties stem from not only the individual contribution of the heterogeneous structure components including the fine/ultrafine grains and deformed coarse grains but also their synergistic effect via hetero-deformation induced strengthening and hardening effects.In summary,our study provides a feasible way to develop new Mg alloys with high strength and good ductility. | Jing Han Jiapeng Sun Yuanming Song Bingqian Xu Zhenquan Yang Songsong Xu Ying Han Guosong Wu Jiyun Zhao | 2023 | Journal of Magnesium and Alloys2023，11，7： | 0 |
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