|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 栽培陆地使用紧张的时间空间的差别分析基于在中国的波伊昂·莱克·埃科科诺米克地区的 emergy显示文摘拿五输入的 emergy 要求作为基础索引,这份报纸从 2000 ~ 2010 在波伊昂·莱克·埃科科诺米克地区在栽培陆地使用紧张分析全部的时间、空间的变化。结果如下被获得:(1 ) 在 10 年的一个时期上,栽培陆地使用紧张在波伊昂·莱克·埃科科诺米克地区指数地增加了;农业机械紧张是全部的输入的最大的比例,包括超过 99.50% 并且逐年增加,它显示农业机械化是在在波伊昂·莱克·埃科科诺米克地区的农业开发的一个基本趋势。(2 ) 属于的县的全部的数字中等 -- 并且低 -- 紧张栽培了陆地使用范畴最大,当属于高紧张的栽培陆地使用和广泛的栽培陆地使用范畴的县的数字最小时。(3 ) 这个地区能被划分成五个区域:高紧张的栽培陆地使用,低紧张的栽培陆地使用的一个中央、东方的区域,低紧张的栽培陆地使用的一个中央区域,中等紧张的栽培陆地使用的一个南部的区域,和中等紧张的栽培陆地使用的一个北区域的一个东方区域。(4 ) 举办了在栽培陆地使用紧张和他们的社会经济的发展水平之间的协调开发的县逐年增加,并且社会经济的发展水平在栽培陆地使用紧张上有逐渐地明显的效果。最后,这份报纸在波伊昂·莱克·埃科科诺米克地区为栽培陆地使用紧张的发展论述建议,特别为在县之中的紧张的不同层次。 | XIE Hualin HE Yafen ZOU Jinlang WU Qun | 2016 | Journal of Geographical Sciences2016，26，10： | 4 |
| 2 | Primary Study on Phytodegradation of Bisphenol A by Elodea nuttallii显示文摘In a microcosm system where Elodea nuttallii and Bisphenol A (BPA) coexist, with the help of Liquid chromatogra-phy-mass spectrometer (LC-MS) and gas chromatography-mass spectrometer (GC-MS), the dynamics of phytodegradation of BPA with concentration 1-20 mg/L and the products of phytodegrada-tion was studied. Antioxidation activity and phospholipids fatty acids were measured to evaluate the effects of BPA on E.nuttallii. The results showed that the half life period of phytodegradation of BPA was less than 15 days. 2-(4-hydroxypheny)-2-(3,4-o-dihy-droxypheny) propane and 2, 2-bis(4-hydroxypheny) propyl alco-hol were identified to be as two possible products of BPA. The peroxidase (POD) activity of E.nuttallii decreased by 50% to 100% compared with that controlled at the end of the experiment. The fatty acid methanol esters (FAMEs) changed obviously too. It showed that oxidation stress and membrane damage would be the two effecting aspects of BPA on E.nuttallii. | ZHANG Bingzhi WU Zhenbin CHENG Shuiping HE Feng WANG Yafen GAO Yunni | 2007 | Wuhan University Journal of Natural Sciences2007，12，6： | 1 |
| 3 | A highly efficient fluorescence-based switch-on detection method of 5-formyluracil in DNA显示文摘在 genomic DNA 的 hydroxylmethyl- 和 formylpyrimidines 的鉴定是在 epigenetics 的一个里程碑事件。相关的地里的众多的实验室正在调查这些和另外的 nucleic 酸修正的生物学。然而,处于检测并且综合的能力的限制拨出修正是妨碍。此处,我们在 5-formyluracil 的选择察觉探索了显著开发在搁浅单人赛并且在温和条件下面的双 stranded DNA。向 5-formyluracil 的打开特性在检测包含 5-formyluracil 的材料的品质上和份量上启用了高 signal-to-noise 比率,它没被 abasic 地点和 5-formylcytosine 的存在影响, 5-formyluracil 的修改 cytosine 对应物。在 5-formyluracil phosphoramidite 的摘要,无毒,便利,和费用效率,合成常规将支持这自然 thymidine 修正的 epigenetic 角色的理解。 | Chaoxing Liu Yuqi Chen Yafen Wang Fan Wu Xiong Zhang Wei Yang Jiaqi Wang Yi Chen Zhiyong He Guangrong Zou Shaoru Wang Xiang Zhou | 2017 | Nano Research2017，10，7： | 0 |
| 4 | Prognostic value of the 21-gene recurrence score in ER-positive,HER2-negative,node-positive breast cancer was similar in nodenegative diseases:a single-center study of 800 patients显示文摘Multi-gene assays have emerged as crucial tools for risk stratification in early-stage breast cancer.This study aimed to evaluate the prognostic significance of the 21-gene recurrence score(RS)in Chinese patients with pN0-l,estrogen receptor-positive(ER+),human epidermal growth factor receptor 2-negative(HER2)breast cancer.Among 800 patients recruited between 2009 and 2016,the median RS was 24(0-69),with 27.4%,46.8%,and 25.9%patients classified into low-,intermediate-,and high-risk groups.Cox regression analysis demonstrated that the high-risk category was associated with significantly higher odds of invasive disease-free survival(IDFS)and distant disease-free survival(DDFS)events compared with the low-risk category(IDFS:HR=2.450,95%Cl 1.017-5.902,P=0.046;DDFS:HR=2.829,95%Cl 1.013-7.901,P=0.047).No significant association between RS category and overall survival(OS)was found(intermediate vs.low:HR=1.244,95%Cl 0.292-5.297,P=0.768;high vs.low:HR=2.933,95%Cl 0.759-11.327,P=0.119).RS,as a continuous variable,was a highly significant predictor for IDFS(HR=1.028,95%Cl 1.010-1.047,P=0.002),DDFS(HR=1.030,95%Cl 1.010-1.051,P=0.003),and OS(HR=1.034,95%Cl 1.007-1.063,P=0.014).Our findings suggested that RS may predict IDFS in Chinese patients with ER+/HER2 breast cancer with NO or N1 disease. | Jiayi Wu Weiqi Gao Xiaosong Chen Chunxiao Fei Lin Lin Weiguo Chen Ou Huang Siji Zhu Jianrong He Yafen Li Li Zhu Kunwei Shen | 2021 | Frontiers of Medicine2021，15，4： | 0 |
| 5 | A nomogram to predict adjuvant chemotherapy recommendation in breast cancer patients with intermediate recurrence score显示文摘Objective: The indication of adjuvant chemotherapy recommendation(ACR) in breast cancer patients with intermediate recurrence score(RS) is controversial. This study investigated the relationship between routine clinicopathological indicators and ACR, and established a nomogram for predicting the probability of ACR in this subset of patients.Methods: Data for a total of 504 consecutive patients with intermediate RS from January 2014 to December2016 were retrospectively reviewed. A nomogram was constructed using a multivariate logistic regression model based on data from a training set(378 cases) and validated in an independent validation set(126 cases). A Youdenderived cut-off value was assigned to the nomogram for accuracy evaluation.Results: The multivariate logistic regression analysis identified that age, histological grade, tumor size, lymph node(LN) status, molecular subtype, and RS were independent predictors of ACR. A nomogram based on these predictors performed well. The P value of the Hosmer-Lemeshow test for the prediction model was 0.286. The area under the curve(AUC) values were 0.905 [95% confidence interval(95% CI): 0.876–0.934] and 0.883(95%CI: 0.824–0.942) in the training and validation sets, respectively. The accuracies of the nomogram for ACR were84.4% in the training set and 82.1% in the validation set.Conclusions: We developed a nomogram to predict the probability of ACR in breast cancer patients with intermediate RS. This model may aid the individual risk assessment and guide treatment decisions in clinical practice. | Feilin Qu Xiaosong Chen Xiaochun Fei Lin Lin Weiqi Gao Yu Zong Jiayi Wu Ou Huang Jianrong He Li Zhu Weiguo Chen Yafen Li Kunwei Shen | 2018 | Chinese Journal of Cancer Research2018，30，2： | 0 |
| 6 | Genome-wide analyses of nonsyndromic cleft lip with or without palate identify 20 new risk loci in the Chinese Han population显示文摘Orofacial clefts(OFCs),particularly cleft lip with or without cleft palate(CL/P)and cleft palate only(CPO),are among the most common birth defects in humans(Mossey et al.,2009;Dixon et al.,2011).The birth prevalence rate of OFCs in China is reported to be as high as 1.66 per thousand newborns. | Bao Li Liang Yong Yafen Yu Yanqin Yu Qi Zhen Huiyao Ge Yiwen Mao Weiwei Chen Yanxia Yu Yirui Wang Zhuo Li Wencheng Fan Chang Zhang Xia Hu Ruixue Zhang Lu Cao Hao Liu Zhuan Bian Miao He Liangdan Sun | 2022 | Journal of Genetics and Genomics2022，49，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员