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| 1 | Novel Water-Based Drilling and Completion Fluid Technology to Improve Wellbore Quality During Drilling and Protect Unconventional Reservoirs显示文摘The efficient exploration and development of unconventional oil and gas are critical for increasing the self-sufficiency of oil and gas supplies in China.However,such operations continue to face serious problems(e.g.,borehole collapse,loss,and high friction),and associated formation damage can severely impact well completion rates,increase costs,and reduce efficiencies.Water-based drilling fluids possess certain advantages over oil-based drilling fluids(OBDFs)and may offer lasting solutions to resolve the aforementioned issues.However,a significant breakthrough with this material has not yet been made,and major technical problems continue to hinder the economic and large-scale development of unconventional oil and gas.Here,the international frontier external method,which only improves drilling fluid inhibition and lubricity,is expanded into an internal-external technique that improves the overall wellbore quality during drilling.Bionic technologies are introduced into the chemical material synthesis process to imitate the activity of life.A novel drilling and completion fluid technique was developed to improve wellbore quality during drilling and safeguard formation integrity.Macroscopic and microscopic analyses indicated that in terms of wellbore stability,lubricity,and formation protection,this approach could outperform methods that use typical OBDFs.The proposed method also achieves a classification upgrade from environmentally protective drilling fluid to an ecologically friendly drilling fluid.The developed technology was verified in more than 1000 unconventional oil and gas wells in China,and the results indicate significant alleviation of the formation damage attributed to borehole collapse,loss,and high friction.It has been recognized as an effective core technology for exploiting unconventional oil and gas resources.This study introduces a novel research direction for formation protection technology and demonstrates that observations and learning from the natural world can provide an inexhaustible source of ideas and inspire the creation of original materials,technologies,and theories for petroleum engineering. | Guancheng Jiang Jinsheng Sun Yinbo He Kaixiao Cui Tengfei Dong Lili Yang Xukun Yang Xingxing Wang | 2022 | Engineering2022，，11： | 11 |
| 2 | ADMETNet:The knowledge base of pharmacokinetics and toxicology network显示文摘A good drug or drug candidate should not only interact with its target molecule effectively and specifically,but also be absorbed into the body,distributed to the right location,metabolized into right compounds,and eliminated out of the body in proper manner.The processes of drug getting into and out of the body involve Absorption,Distribution,Metabolism,and Excretion(ADME),which | Quan Xu Ke Liu Xingming Lin Yangmei Qin Linshan Chen Jiao Cheng Mindong Zhong Qiushun He Yinbo Li Tingwu Wang Jianbo Pan Menglu Peng Lixia Yao Zhiliang Ji | 2017 | Journal of Genetics and Genomics2017，44，5： | 2 |
| 3 | Hypofraction radiotherapy of liver tumor using cone beam computed tomography guidance combined with active breath control by long breath-holding显示文摘 | Renming Zhong Jin Wang Xiaoqin Jiang Yinbo He Hong Zhang Nianyong Chen Sen Bai Feng Xu | 2011 | Radiotherapy and Oncology2011，，： | 1 |
| 4 | A saturated saltwater drilling fluid based on salt-responsive polyampholytes显示文摘Based on special antipolyelectrolyte effect of zwitterion polymer with same quantity of anionic and cationic charges, we developed two types of salt-responsive polyampholytes, one with high molecular weight and low charge density(HvL) and the other with low molecular weight and high charge density(LvH), by inverse emulsion polymerization. Molecular structure and salt-responsiveness of them were characterized by 1 H-NMR and rheology measurement, respectively. HvL and LvH were evaluated in saturated-salt bentonite suspension and influences of their ratio on apparent viscosity and fluid loss were investigated as well. The results indicate that HvL is better at decreasing fluid loss while LvH is better at maintaining low viscosity. A saturated saltwater drilling fluid centering on HvL and Lv H with simple formula was designed and applied. It is indicated that salt-responsive polyampholytes are fundamentally better than AM-AMPS anionic copolymer and AM-AMPS-DMDAAC amphoteric copolymer. The saturated saltwater drilling fluid has excellent thermal stability, tolerance to bentonite and shale cuttings, and certain resistance to CaCl_2. Salt-responsive polyampholytes can be used in KCl-saturated drilling fluid, with universal adaptability. | JIANG Guancheng HE Yinbo CUI Wuge YANG Lili YE Chenxi | 2019 | Petroleum Exploration and Development2019，46，2： | 0 |
| 5 | Multiscale mechanics of noncovalent interface in graphene oxide layered nanocomposites显示文摘Noncovalent interfaces play a vital role in inelastic deformation and toughening mechanisms in layered nanocomposites due to their dynamical recoverability. When interfacial engineering is applied to design layered nanocomposites, shear-lag analysis is usually implemented to evaluate the capability of interfacial loading transfer. Here, we introduce a multiscale shear-lag model that correlates macroscale mechanical properties with the molecular mechanisms to quantify the effects of interfacial configuration in graphene oxide(GO) layered nanocomposites. By investigating the mechanical responses of commensurate and incommensurate interfaces, we identify that the commensurate interface exhibits a pronounced size effect due to the nucleation and propagation of interfacial defects, whereas the incommensurate interface displays uniform deformation. Our predictions are further validated through large-scale molecular dynamics simulations for GO layered nanocomposites. This work demonstrates how size effects and interfacial configurations can be exploited to fabricate layered nanocomposites with superior mechanical properties despite relying on weak noncovalent interfaces. | ZeZhou He YinBo Zhu HengAn Wu | 2022 | Theoretical & Applied Mechanics Letters2022，12，1： | 0 |
| 6 | The biodiesel-based flat-rheology drilling fluid system显示文摘As the base oil of the current flat-rheology synthetic drilling fluid is high in cost and not renewable, the biodiesel-based flat-rheology drilling fluid with low-cost, environmental protection and renewable advantage was studied. Based on the optimization of raw materials, a cheap, environment-friendly biodiesel of soybean oil ethyl ester with good fluidity at low temperature was selected as the base oil. By selecting high oil-water ratio and introducing cationic surfactant into the auxiliary emulsifier, the thickening of biodiesel-based emulsion caused by hydrolysis and saponification after high-temperature aging was effectively eliminated. The organoclay prepared with cationic modifier of hexadecyl trimethyl ammonium chloride was used to improve the rheologic properties, stability and fluid loss of the drilling fluid while preventing low-temperature thickening. A flat-rheology modifier was synthesized with dimer fatty acid and cocoanut fatty acid diethanolamide, which could form strong network structure in the biodiesel-based drilling fluid to adjust effectively rheological properties of the drilling fluid. A biodiesel-based flat-rheology drilling fluid system with the density of 1.2 g/cm^(3) has been formulated which has constant rheology in the temperature range of 2-90 ℃, temperature tolerance of 160 ℃, seawater salinity tolerance of 5%, shale cuttings tolerance of 10%, and is environmentally friendly. | JIANG Guancheng SHI He HE Yinbo | 2022 | Petroleum Exploration and Development2022，49，1： | 0 |
| 7 | Research status and development directions of intelligent drilling fluid technologies显示文摘By reviewing the current status of drilling fluid technologies with primary intelligence features at home and abroad,the development background and intelligent response mechanisms of drilling fluid technologies such as variable density,salt response,reversible emulsification,constant rheology,shape memory loss prevention and plugging,intelligent reservoir protection and in-situ rheology control are elaborated,current issues and future challenges are analyzed,and it is pointed out that intelligent material science,nanoscience and artificial intelligence theory are important methods for future research of intelligent drilling fluid technology of horizontal wells with more advanced intelligent features of'self-identification,self-tuning and self-adaptation'.Based on the aforementioned outline and integrated with the demands from the drilling fluid technology and intelligent drilling fluid theory,three development suggestions are put forward:(1)research and develop intelligent drilling fluids responding to variable formation pressure,variable formation lithology and fluid,variable reservoir characteristics,high temperature formation and complex ground environmental protection needs;(2)establish an expert system for intelligent drilling fluid design and management;and(3)establish a real-time intelligent check and maintenance processing network. | JIANG Guancheng DONG Tengfei CUI Kaixiao HE Yinbo QUAN Xiaohu YANG Lili FU Yue | 2022 | Petroleum Exploration and Development2022，49，3： | 0 |
| 8 | Molecular levers enable anomalously enhanced strength and toughness of cellulose nanocrystal at cryogenic temperature显示文摘The quest for widespread applications especially in extreme environments accentuates the necessity to design materials with robust mechanical and thermodynamic stabilities.Almost all existing materials yield temperature-variant mechanical properties,essentially determined by their different atomic bonding regimes.In general,weak non-covalent interactions are considered to diminish the structural anti-destabilization of covalent crystals despite the toughening effect.Whereas,starting from multiscale theoretical modeling,we herein reveal an anomalous stabilizing effect in cellulose nanocrystals(CNCs)by the cooperation between the non-covalent hydrogen bonds and covalent glucosidic skeleton,namely molecular levers(MLs).It is surprising to find that the hydrogen bonds in MLs behave like covalent bindings under cryogenic conditions,which provide anomalously enhanced strength and toughness for CNCs.Thermodynamic analyses demonstrate that the unique dynamical mechanical behaviors from ambient to deep cryogenic temperatures are synergetic results of the intrinsic temperature dependence veiled in MLs and the overall thermo-induced CNC destabilization/amorphization.As the consequence,the variation trend of mechanical strength exhibits a bilinear temperature dependence with~77 K as the turning point.Our underlying investigations not only establish the bottom–up interrelations from the hydrogen bonding thermodynamics to the crystal-scale mechanical properties,but also facilitate the potential application of cellulose-based materials at extremely low temperatures such as those in outer space. | YuanZhen Hou Jun Xia ZeZhou He YinBo Zhu HengAn Wu | 2023 | Nano Research2023，16，5： | 0 |
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