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| 1 | A comprehensive classification method for VOC emission sources to tackle air pollution based on VOC species reactivity and emission amounts显示文摘In China, volatile organic compound(VOC) control directives have been continuously released and implemented for important sources and regions to tackle air pollution. The corresponding control requirements were based on VOC emission amounts(EA), but never considered the significant differentiation of VOC species in terms of atmospheric chemical reactivity. This will adversely influence the effect of VOC reduction on air quality improvement. Therefore,this study attempted to develop a comprehensive classification method for typical VOC sources in the Beijing–Tianjin–Hebei region(BTH), by combining the VOC emission amounts with the chemical reactivities of VOC species. Firstly, we obtained the VOC chemical profiles by measuring 5 key sources in the BTH region and referencing another 10 key sources, and estimated the ozone formation potential(OFP) per ton VOC emission for these sources by using the maximum incremental reactivity(MIR) index as the characteristic of source reactivity(SR). Then, we applied the data normalization method to respectively convert EA and SR to normalized EA(NEA) and normalized SR(NSR) for various sources in the BTH region.Finally, the control index(CI) was calculated, and these sources were further classified into four grades based on the normalized CI(NCI). The study results showed that in the BTH region,furniture coating, automobile coating, and road vehicles are characterized by high NCI and need to be given more attention; however, the petro-chemical industry, which was designated as an important control source by air quality managers, has a lower NCI. | Guohao Li Wei Wei Xia Shao Lei Nie Hailin Wang Xiao Yan Rui Zhang | 2018 | Journal of Environmental Sciences2018，30，5： | 32 |
| 2 | Multi-User Connection Performance Assessment of NOMA Schemes for Beyond 5G显示文摘Non-orthogonal multiple access(NOMA)is proved to be useful to satisfy the requirements of beyond 5th generation such as massive multi-user connection.Here we compare the performances of two NOMA schemes:low code rate spreading(LCRS)scheme and interleaver division multiple access(IDMA)scheme.It is found that LCRS is superior to IDMA when number of users is small due to coding gain achieved.While IDMA is preferred when number of users is high because repetition applied in IDMA can suppress multi-user interference effectively.And interleaver is important in IDMA for randomizing the interference.Also,this paper evaluates the impact of channel decoder.It is observed that Log-MAP decoder has much better performance than that of Max-Log-MAP when number of users is large.Thus,it is recommended to use Log-MAP decoder in NOMA in high user overloading case.We also compared the performance of NOMA by using different type of channel codes.We find that NOMA using specific convolutional code has a better performance than that of using specific LDPC code when number of users is high. | Baoxi Wang Chunlin Yan Wei Liu Hailin Zhang | 2020 | China Communications2020，17，12： | 3 |
| 3 | Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip显示文摘EGFR mutations companion diagnostics have been proved to be crucial for the efficacy of tyrosine kinase inhibitor targeted cancer therapies. To uncover multiple mutations occurred in minority of EGFR-mutated cells,which may be covered by the noises from majority of unmutated cells, is currently becoming an urgent clinical requirement. Here we present the validation of a microfluidic-chip-based method for detecting EGFR multimutations at single-cell level. By trapping and immunofluorescently imaging single cells in specifically designed silicon microwells, the EGFR-expressed cellswere easily identified. By in situ lysing single cells, the cell lysates of EGFR-expressed cells were retrieved without cross-contamination. Benefited from excluding the noise from cells without EGFR expression, the simple and cost-effective Sanger's sequencing, but not the expensive deep sequencing of the whole cell population, was used to discover multi-mutations. We verified the new method with precisely discovering three most important EGFR drugrelated mutations from a sample in which EGFR-mutated cells only account for a small percentage of whole cell population. The microfluidic chip is capable of discovering not only the existence of specific EGFR multi-mutations,but also other valuable single-cell-level information: on which specific cells the mutations occurred, or whether different mutations coexist on the same cells. This microfluidic chip constitutes a promising method to promote simple and cost-effective Sanger's sequencing to be a routine test before performing targeted cancer therapy. | Ren Li Mingxing Zhou Jine Li Zihua Wang Weikai Zhang Chunyan Yue Yan Ma Hailin Peng Zewen Wei Zhiyuan Hu | 2018 | Nano-Micro Letters2018，10，1： | 2 |
| 4 | Path PPI: an integrated dataset of human pathways and protein-protein interactions显示文摘Integration of pathway and protein-protein interaction(PPI) data can provide more information that could lead to new biological insights. PPIs are usually represented by a simple binary model, whereas pathways are represented by more complicated models. We developed a series of rules for transforming protein interactions from pathway to binary model, and the protein interactions from seven pathway databases, including PID, Bio Carta, Reactome, Net Path, INOH, SPIKE and KEGG, were transformed based on these rules. These pathway-derived binary protein interactions were integrated with PPIs from other five PPI databases including HPRD, Int Act, Bio GRID, MINT and DIP, to develop integrated dataset(named Path PPI). More detailed interaction type and modification information on protein interactions can be preserved in Path PPI than other existing datasets. Comparison analysis results indicate that most of the interaction overlaps values(OAB) among these pathway databases were less than 5%, and these databases must be used conjunctively. The Path PPI data was provided at http://proteomeview. hupo.org.cn/Path PPI/Path PPI.html. | TANG HaiLin ZHONG Fan LIU Wei HE FuChu XIE HongWei | 2015 | Science China(Life Sciences)2015，58，6： | 2 |
| 5 | Environmental resistance and mechanical performance of basalt and glass fibers显示文摘 | Wei Bin Cao Hailin Song Shenhua | 2010 | Materials Sci- ence and EngineeringA2010，，527： | 1 |
| 6 | Environmental resistance and mechanical performance of basalt and glass fibers显示文摘 | Bin Wei Hailin Cao Shenhua Song | 2010 | Materials Science & Engineering A2010，，18： | 1 |
| 7 | Environmental re- sistance and mechanical performance of basalt and glass fibers 显示文摘 | Wei Bin Cao Hailin Song Shenhua | 2010 | Materials Science and Engineering2010，527，1819： | 1 |
| 8 | Tensile behavior contrast of basalt and glass fibers after chemical treatment 显示文摘 | Wei Bin Can Hailin Song Shenhua | 2010 | Materials and Design2010，，31： | 1 |
| 9 | Degradation of basalt fibre and glass fibre/epoxy resin composites in seawater 显示文摘 | Wei Bin Cao Hailin Song Shenhua | 2011 | Corrosion Science2011，，53： | 1 |
| 10 | Environmental resis- tance and mechanical performance of basalt and glass fibers 显示文摘 | Wei Bin Cao Hailin Song Shenhua | 2010 | Mater Sci Eng A2010，527，： | 1 |
| 11 | Transcriptional factors p300 and MRTF-A synergistically enhance the expression of migration-related genes in MCF-7 breast cancer cells显示文摘 | Hongpeng He Dandan Wang Hailin Yao Zhaoqiang Wei Yongwei Lai Juan Hu Xuena Liu Yijie Wang Hao Zhou Nan Wang Xue-Gang Luo Tong-Cun Zhang | 2015 | Biochemical and Biophysical Research Communicatio2015，，： | 1 |
| 12 | Tensile behavior contrast of basalt and glass fibers after chemical treatment显示文摘 | WEI Bin CAO Hailin SONG Shenhua | | 0，，09： | 1 |
| 13 | Environmental resist- ance and mechanical performance of basalt and glass fibers显示文摘 | WEI Bin CAO Hailin SONG Shenhua | 2010 | Materials Science and Engineering A2010，527，1819： | 1 |
| 14 | miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer’s disease targets TGF-β type II receptor显示文摘 | Hailin Wang Jialin Liu Yuanyuan Zong Yanfeng Xu Wei Deng Hua Zhu Ying Liu Chunmei Ma Lan Huang Lianfeng Zhang Chuan Qin | 2010 | Brain Research2010，，： | 1 |
| 15 | Tensile behaviors con- trast of basalt and glass fibers after chemical treatment显示文摘 | WEI Bin CAO Hailin SONG Shenhua | 2010 | Materials and Design2010，31，9： | 1 |
| 16 | Environmental re- sistance and mechanical performance of basalt and glass fibers 显示文摘 | Wei Bin Cao Hailin Song Shenhua | 2010 | Materials Science and Engineering2010，527，1819： | 1 |
| 17 | Tensile Behavior Contrast of Basalt and Glass Fibers After Chemical Treatment显示文摘 | Wei Bin Gao Hailin Song Shenhua | 2010 | Materials and Design2010，31，： | 1 |
| 18 | Fly-Ash-Amended Sand as Filter Media in Bioretention Cells to Improve Phosphorus Removal显示文摘 | Zhang Wei Brown Glenn O Storm Daniel E Zhang Hailin | 2008 | Water Environment Research2008，，6： | 1 |
| 19 | miR-214 promotes tumorigenesis by targeting lactotransferrin in nasopharyngeal carcinoma显示文摘 | Min Deng Qiurong Ye Zailong Qin Ying Zheng Wei He Hailin Tang Yanhong Zhou Wei Xiong Ming Zhou Xiaoling Li Qun Yan Jian Ma Guiyuan Li | 2013 | Tumor Biology2013，，： | 1 |
| 20 | S100B Transgenic Mice Develop Features of Parkinson’s Disease显示文摘 | Jialin Liu Hailin Wang Lianfeng Zhang Yanfeng Xu Wei Deng Hua Zhu Chuan Qin | 2011 | Archives of Medical Research2011，，1： | 1 |
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