|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A rare case of hyaline-type Castleman disease in the liver显示文摘Castleman disease often develops in the neck, mediastinum and pulmonary hilum. Its onset in the peritoneal cavity is very rare. The patient, a woman in her 70s, was referred to our department for a detailed examination of an abdominal mass. On abdominal ultrasonography, computed tomography scan, magnetic resonance imaging and positron emission tomography, a mass approximately 15 mm in diameter was noted in the hepatic S6. We attempted radical treatment and conducted a laparoscope-assisted right lobectomy. On the basis of histopathological findings, the patient was diagnosed as having hyaline type Castleman disease in the liver, a very rare condition. | Hisaaki Miyoshi Shima Mimura Takako Nomura Joji Tani Asahiro Morishita Hideki Kobara Hirohito Mori Hirohito Yoneyama Akihiro Deguchi Takashi Himoto Naoki Yamamoto Keiichi Okano Yasuyuki Suzuki Tsutomu Masaki | 2013 | World Journal of Hepatology2013，5，7： | 14 |
| 2 | A combination therapy of ethanol injection and radiofrequency ablation under general anesthesia for the treatment of hepatocellular carcinoma显示文摘AIM: To summarize the effects of laparoscopic ethanol injection and radiofrequency ablation (L-EI-RFA), thora- coscopic (T-EI-RFA) and open-surgery assisted EI-RFA (O-EI-RFA) under general anesthesia for the treatment of hepatocellular carcinoma (HCC). METHODS: Time-lag performance of RFA after ethanol injection (Time-lag PEI-RFA) was performed in all cases. The volume of coagulated necrosis and the applied en- ergy for total and per unit volume coagulated necrosis were examined in the groups treated under general (group G) or local anesthesia (group L). RESULTS: The results showed that the total applied energy and the applied energy per unit volume of whole and marginal, coagulated necrosis were significantly larger in group G than those in the group L, resulting in a larger volume of coagulated necrosis in the group G. The rate of local tumor recurrence within one year was extremely low in group G. CONCLUSION: These results suggest that EI-RFA, un- der general anesthesia, may be effective for the treat- ment of HCC because a larger quantity of ethanol and energy could be applied during treatment under pain- free condition for the patients. | Kazutaka Kurokohchi Seishiro Watanabe Hirohito Yoneyama Akihiro Deguchi Tsutomu Masaki Takashi Himoto Hisaaki Miyoshi Hamdy Saad Mohammad Akira Kitanaka Tomohiko Taminato Shigeki Kuriyama | 2008 | World Journal of Gastroenterology2008，14，13： | 10 |
| 3 | Reduction effect of bacterial counts by preoperative saline lavage of the stomach in performing laparoscopic and endoscopic cooperative surgery显示文摘AIM:To investigate the effects of gastric lavage with2000 mL of saline in laparoscopic and endoscopic cooperative surgery.METHODS:Twenty two patients who were diagnosed with a gastric gastrointestinal stromal tumor were enrolled.In former term,irrigations of the stomach were conducted whenever it was necessary,not systematically(Non systemic lavage group).In latter term,the stomach was thoroughly cleaned with 2000 mL of saline using an endoscope with a water jet,and Duodenal balloon occlusion was conducted to prevent refluxedbile and pancreatic juice(Systemic lavage+balloon occlusion group).The gastric wall was sprayed with 20mL of distilled water,and 20 mL of gastric juice was collected in a sterile tube and submitted for culture.20mL of ascites was also collected from the laparoscopic ports and submitted for culture.We compared WBC,CRP,BT between two groups,and verify the reduction effect of bacterial counts in Systemic lavage+balloon occlusion group.RESULTS:WBC count before,1 d after,and 3 d after laparoscopic and endoscopic cooperative surgery(LECS)were 5060(95%CI:4250-9640),12140(6050-14110),and 6910(5320-12520)in Non systemic lavage group,4400(3660-7620),8910(6480-10980),and 5950(4840-7860)in Systemic lavage+balloon occlusion group.Significant differences between two groups at the day after LECS(P=0.029)and the 3 d after LECS(P=0.042).CRP levels in Non systemic lavage group and in Systemic lavage+balloon occlusion group were significantly different at the day after LECS(P=0.005)and the 3 d after LECS(P=0.028).BTs(℃)in Non systemic lavage group and in Systemic lavage+balloon occlusion group were also significantly different at the day after LECS(P=0.004)and the 3 d after LECS(P=0.006).In a logarithmic comparison,bacterial load before gastric lavage,after lavage,and ascites culture were 6.08(95%CI:4.04-6.97),0.48(0-0.85),and 0.21(0-0.56).The bacterial counts before and after gastric lavage were significantly suppressed(P=0.007),but no significant difference between gastric juice culture after lavage and ascites(P=0.154).CONCLUSION:Pre-LECS lavage with 2000 mL of saline exhibited a bacteria-reducing effect equivalent to disinfectants and obtained favorable results in terms of clinical symptoms and data. | Hirohito Mori Hideki Kobara Takaaki Tsushimi Shintaro Fujihara Noriko Nishiyama Tae Matsunaga Maki Ayaki Tatsuo Yachida Joji Tani Hisaaki Miyoshi Asahiro Morishita Tsutomu Masaki | 2014 | World Journal of Gastroenterology2014，20，42： | 9 |
| 4 | Diabetes mellitus and metformin in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is the leading cause of cancer-related death worldwide. Diabetes mellitus, a risk factor for cancer, is also globally endemic. The clinical link between these two diseases has been the subject of investigation for a century, and diabetes mellitus has been established as a risk factor for HCC. Accordingly, metformin, a first-line oral anti-diabetic, was first proposed as a candidate anti-cancer agent in 2005 in a cohort study in Scotland. Several subsequent large cohort studies and randomized controlled trials have not demonstrated significant efficacy for metformin in suppressing HCC incidence and mortality in diabetic patients; however, two recent randomized controlled trials have reported positive data for the tumor-preventive potential of metformin in non-diabetic subjects. The search for biological links between cancer and diabetes has revealed intracellular pathways that are shared by cancer and diabetes. The signal transduction mechanisms by which metformin suppresses carcinogenesis in cell lines or xenograft tissues and improves chemoresistance in cancer stem cells have also been elucidated. This review addresses the clinical and biological links between HCC and diabetes mellitus and the anti-cancer activity of metformin in clinical studies and basic experiments. | Koji Fujita Hisakazu Iwama Hisaaki Miyoshi Joji Tani Kyoko Oura Tomoko Tadokoro Teppei Sakamoto Takako Nomura Asahiro Morishita Hirohito Yoneyama Tsutomu Masaki | 2016 | World Journal of Gastroenterology2016，22，27： | 7 |
| 5 | Effect of equal-channel angular pressing on pitting corrosion resistance of anodized aluminum-copper alloy显示文摘The effect of equal-channel angular pressing(ECAP) on the pitting corrosion resistance of anodized Al-Cu alloy was investigated by electrochemical techniques in a solution containing 0.2 mol/L AlCl3 and also by surface analysis.Anodizing was conducted for 20 min at 200 and 400 A/m2 in a solution containing 1.53 mol/L H2SO4 and 0.018 5 mol/L Al2(SO4)3·16H2O at 20 ℃.Anodized Al-Cu alloy was immediately dipped in boiling water for 20 min to seal the micro pores present in anodic oxide films.The time required before initiating pitting corrosion of anodized Al-Cu alloy is longer with ECAP than without,indicating that ECAP process improves the pitting corrosion resistance of anodized Al-Cu alloy.Second phase precipitates such as Si,Al-Cu-Mg and Al-Cu-Si-Fe-Mn intermetallic compounds are present in Al-Cu alloy and the size of these precipitates is greatly decreased by application of ECAP.Al-Cu-Mg intermetallic compounds are dissolved during anodization,whereas the precipitates composed of Si and Al-Cu-Si-Fe-Mn remain in anodic oxide films due to their more noble corrosion potential than Al.FE-SEM and EPMA observation reveal that the pitting corrosion of anodized Al-Cu alloy occurs preferentially around Al-Cu-Si-Fe-Mn intermetallic compounds,since the anodic oxide films are absent at the boundary between the normal oxide films and these impurity precipitates.The improvement of pitting corrosion resistance of anodized Al-Cu alloy processed by ECAP appears to be attributed to a decrease in the size of precipitates,which act as origins of pitting corrosion. | In-Joon SON Hiroaki NAKANO Satoshi OUE Shigeo KOBAYASHI Hisaaki FUKUSHIMA Zenji HORITA | 2009 | 中国有色金属学会会刊:英文版2009，19，4： | 5 |
| 6 | Effect of the anti-diabetic drug metformin in hepatocellular carcinomain vitro and in vivo显示文摘 | Hisaaki Miyoshi Kiyohito Kato Hisakazu Iwama Emiko Maeda Teppei Sakamoto Koji Fujita Yuka Toyota Joji Tani Takako Nomura Shima Mimura Mitsuyoshi Kobayashi Asahiro Morishita Hideki Kobara Hirohito Mori Hirohito Yoneyama Akihiro Deguchi Takashi Himoto Kazut | 2014 | International Journal of Oncology2014，，1： | 3 |
| 7 | Long-Term Results of Subtotal Esophagectomy with Three-Field Lymphadenectomy for Carcinoma of the Thoracic Esophagus显示文摘 | Masamichi Baba Takashi Aikou Heiji Yoshinaka Shoji Natsugoe Toshitaka Fukumoto Hisaaki Shimazu Kouhei Akazawa | 1994 | Annals of Surgery1994，，3： | 1 |
| 8 | Thermomechanical constitutive model of shape memory polymer显示文摘 | KAYO OKUMURA SHUNICHI HAYASHI | 2001 | Mechanics of Materials2001，33，10： | 1 |
| 9 | Removal of Aqueous Ammonium with Magnesium Phosphates Obtained from the Ammonium-elimination of Magnesium Ammonium Phosphate显示文摘 | Shigeru Sugiyama Masahiko Yokoyama Hisaaki Ishizuka | 2005 | Journal of Colloid and Interface Science2005，，292： | 1 |
| 10 | 显示文摘 | Hisaaki Tobushi | 1998 | Mechanics of Materials1998，30，： | 1 |
| 11 | Lead-free Piezoceramics 显示文摘 | Yasuyoshi Saito Hisaaki Takao Toshihiko Tani | 2004 | Nature2004，432，： | 1 |
| 12 | Synthesis of super-high-molecular-weight poly-γ-glutamic acid by Bacillus subtilis subsp. chungkookjang显示文摘 | Chung Park Jae-Chul Choi Yoon-Ho Choi Hisaaki Nakamura Kazuya Shimanouchi Terumi Horiuchi Haruo Misono Tomomitsu Sewaki Kenji Soda Makoto Ashiuchi Moon-Hee Sung | 2005 | Journal of Molecular Catalysis B Enzymatic2005，，4： | 1 |
| 13 | Removal of aqueous ammonium with magnesium phosphates obtained from the ammonium-elimination of magnesium ammonium phosphate显示文摘 | Shigeru Sugiyama Masahiko Yokoyama Hisaaki Ishizuka | 2005 | Journal of Colloid and Interface Science2005，292，： | 1 |
| 14 | Degradation mechanisms of cable insulation materials during radiation–thermal ageing in radiation environment显示文摘 | Tadao Seguchi Kiyotoshi Tamura Takeshi Ohshima Akihiko Shimada Hisaaki Kudoh | 2010 | Radiation Physics and Chemistry2010，，2： | 1 |
| 15 | Lead-free piezoceramics 显示文摘 | Saito Y Hisaaki T Tani T | 2004 | Nature2004，432，11： | 1 |
| 16 | Metallo-lactamase-producing gram- negative bacilli:laboratory-based surveillance in cooperation with 13 clinical laboratories in the Kinki Region of Japan显示文摘 | Hisaaki N Masaru K | 2004 | J Clin Microbio12004，42，11： | 1 |
| 17 | A prediction method for horizontal plane behavior of FPSO under the single point mooring 显示文摘 | Koichi Masuda Takayuki Asanuma Hisaaki Maeda | 2002 | Offshore Mechanics and Arctic Engineering2002，21，1： | 1 |
| 18 | 显示文摘 | Yasuyoshi S Hisaaki T Toshihiko T | 2004 | Nature2004，432，： | 1 |
| 19 | Expression of angiogenic factors in hepatocarcinogenesis: Identificationby antibody arrays显示文摘 | Takako Nomura Asahiro Morishita Gong Jian Shima Mimura Kiyohito Kato Kei Nomura Joji Tani Hisaaki Miyoshi Hirohito Yoneyama Teppei Sakamoto Koji Fujita Emiko Maeda Hideki Kobara Hirohito Mori Hisakazu Iwama Tsutomu Masaki | 2013 | Oncology Reports2013，，5： | 1 |
| 20 | Antitumor effect of metformin in esophageal cancer: In vitro study显示文摘 | Mitsuyoshi Kobayashi Kiyohito Kato Hisakazu Iwama Shintaro Fujihara Noriko Nishiyama Shima Mimura Yuka Toyota Takako Nomura Kei Nomura Joji Tani Hisaaki Miyoshi Hideki Kobara Hirohito Mori Koji Murao Tsutomu Masaki | 2013 | International Journal of Oncology2013，，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员