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| 1 | China's lakes at present:Number,area and spatial distribution显示文摘Based on 11004 satellite images from CBERS CCD and Landsat TM/ETM,changes in the spatial characteristics of all lakes in China were determined following pre-established interpretation rules.This dataset was supported by 6843 digital raster images(1:100000 and 1:50000),a countrywide digital vector dataset(1:250000),and historical literature.Comparative data were corrected for seasonal variations using precipitation data.There are presently 2693 natural lakes in China with an area greater than 1.0 km2,excluding reservoirs.These lakes are distributed in 28 provinces,autonomous regions and municipalities and have a total area of 81414.6 km2,accounting for-0.9% of China's total land area.In the past 30 years,the number of newly formed and newly discovered lakes with an area greater than 1.0 km2 is 60 and 131,respectively.Conversely,243 lakes have disappeared in this time period. | MA RongHua YANG GuiShan DUAN HongTao JIANG JiaHu WANG SuMin FENG XueZhi LI AiNong KONG FanXiang XUE Bin WU JingLu LI ShiJie | 2011 | Science China Earth Sciences2011，54，2： | 79 |
| 2 | Monitoring lake changes of Qinghai-Tibetan Plateau over the past 30 years using satellite remote sensing data显示文摘During the years 2006–2009,lakes in the Qinghai-Tibetan Plateau(QTP)were investigated using satellite remote sensing strategies.We report the results of this investigation as well as follow-up research and expanded work.For the investigation,we mainly focused on lakes whose areas are more than 1 km2.The remote sensing data that we used included 408 scenes of CBERS CCD images and 5 scenes of Landsat ETM?images in Qinghai Province and Tibet Autonomous Region.All these data were acquired around years 2005–2006.Besides remote sensing images,we also collected 1,259 topographic maps.Numbers and areas of lakes were analyzed statistically,which were then compared with those coming from the first lake investigation(implemented between the1960s and 1980s).According to our investigation,up to and around year 2005–2006,the total number of lakes in the QTP was 1,055(222 in Qinghai and 833 in Tibet),accounting for more than 30%of that of China.Thirty newborn lakes with area[1 km2were found,and 5 dead lakes with initial area[1 km2were also found.Among those 13 big lakes([500 km2),Yamzhog Yumco had seriously shrunk,and it has continued to shrink in recent years;Qinghai Lake had shrunk during the period,but some new researches indicated that it has been expanding since the year 2004;Siling Co,Nam Co,and Chibuzhang Co had expanded in the period.We divided the newborn lakes into six categories according to their forming reasons,including river expansion,wetland conversion,etc.The changes of natural conditions led to the death of four lakes,and human exploitation was the main reason for the death of Dalianhai Lake in Qinghai.We picked out three regions which were sensitive to the change of climate and ecological environment:Nagqu Region,Kekexili Region,and the source area of the Yellow River(SAYR).Lakes in both Nagqu and Kekexili have been expanded;meanwhile,most lakes in the SAYR have obviously been shrunk.These regional patterns of lake changes were highly related to variations of temperature,glacier,precipitation,and evaporation.Our investigation and analysis will provide references for researches related to lake changes in the QTP and the response to climate fluctuations. | Wei Wan Pengfeng Xiao Xuezhi Feng Hui Li Ronghua Ma Hongtao Duan Limin Zhao | 2014 | Chinese Science Bulletin2014，59，10： | 22 |
| 3 | Matrine reduces the proliferation and invasion of colorectal cancer cells via reducing the activity of p38 signaling pathway显示文摘Matrine 被使用了在反煽动性并且反癌症治疗很长时间。然而,在 colorectal 癌症(CRC ) 的反变形的效果和相关机制仍然是不清楚的。在这研究,我们调查了 matrine 的管理是否能经由调整表明小径的 p38 禁止人的 CRC 房间的增长,活动性,和侵略。结果证明 matrine 在 vitro 并且在 vivo 禁止了 CRC 房间的移植和侵略。在为 24 h 与 matrine 被对待以后,另外,表示在 CRC 房间矩阵 metalloproteinase-2 (MMP-2 ) 和 MMP-9 以及朊酶活动铺平以一种剂量依赖者方式被减少。而且, matrine 显然减少了 p38 的 phosphorylation 水平。有 p38 禁止者(SB203580 ) 和 matrine 的联合治疗在 CRC 房间导致了侵略以及 MMP-2/-9 表示的 synergistic 减小。matrine 在 vivo 禁止了 CRC 肿瘤的增长和转移,这也被发现。在结论, p38 发信号小径可以由减少 MMP-2/-9 的表示在 CRC 房间的移植和侵略上在 matrine 的禁止的效果包含,建议 matrine 可以是为 CRC 的一个潜在的治疗学的代理人。 | Hongtao Ren Shuqun Zhang Hongbing Ma Yali Wang Di Liu Xijing Wang Zhongwei Wang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 16 |
| 4 | MiR-98 promotes chondrocyte apoptosis by decreasing Bcl-2 expression in a rat model of osteoarthritis显示文摘 | Jing Wang Lingqiang Chen Song Jin Jun Lin Hongmei Zheng Hong Zhang Hongtao Fan Fang He Sha Ma Qin Li | 2016 | Acta Biochimica et Biophysica Sinica2016，48，10： | 8 |
| 5 | Velvet antler polypeptide is able to induce differentiation of neural stem cells towards neurons in vitro显示文摘OBJECTIVE: To investigate the neural differentiation capacity of water extraction of velvet antler.METHODS: Velvet antler(Cervus Nippon Temminck) polypeptide(VAP) was used to differentiate neural stem cells(NSCs) towards neurons in the study. Firstly, we obtain the polypeptides of VAP by water extraction. Secondly, we observed the morphology, assayed the factors in the media by enzyme-linked immunosorbent assay, and detected the special neural molecules by immuno fl uorescence staining. NSCs were cultured on the cell climbing film. After neuronal differentiation, differentiated NSCs were mounted for immunocytochemistry with immunofluorescence technique.RESULTS: The differentiating cells look like neuron,some special factors, such as Glial cell line-derived neurotrophic factor, nerve growth factor, in the media can be detected while differentiated neuron-like cells can express the special neural molecules.CONCLUSION: Differentiation of NSCs towards neurons can be induced by velvet antler polypeptide. | Zhang Lihong Zhuang Zhihong Sun Yanan Ma Shuhua Yang Weifeng Lei Hongtao Zuo Junling Ouyang Jingfeng Wang Yi | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 8 |
| 6 | High strength and high conductivity Cu alloys: A review显示文摘High strength and high conductivity(HSHC) Cu alloys are widely used in many fields,such as high-speed electric railway contact wires and integrated circuit lead frames. Pure Cu is well known to have excellent electrical conductivity but rather low strength. The main concern of HSHC Cu alloys is how to strengthen the alloy efficiently. However,when the Cu alloys are strengthened by a certain method,their electrical conductivity will inevitably decrease to a certain extent. This review introduces the strengthening methods of HSHC Cu alloys. Then the research progress of some typical HSHC Cu alloys such as Cu-Cr-Zr,Cu-Ni-Si,Cu-Ag,Cu-Mg is reviewed according to different alloy systems. Finally,the development trend of HSHC Cu alloys is forecasted. It is pointed out that precipitation and micro-alloying are effective ways to improve the performance of HSHC Cu alloys. At the same time,the production of HSHC Cu alloys also needs to comply with the large-scale,low-cost development trend of industrialization in the future. | YANG HuiYa MA ZiChao LEI ChenHui MENG Liang FANG YouTong LIU JiaBin WANG HongTao | 2020 | Science China(Technological Sciences)2020，63，12： | 7 |
| 7 | Comparison of the activities of binder-added and binder-free Mo/HZSM-5 catalysts in methane dehydroaromatization at 1073 K in periodic CH_4-H_2 switch operation mode显示文摘Three industry-supplied,well-shaped Mo/HZSM-5 catalysts,two binder-added and one binder-free,were tested for the first time in methane dehydroaromatization to benzene at 1073 K and 10000 mL/(g h)in periodic CH4-H2 switch operation mode,and their catalytic performances were compared with those of three self-prepared,binder-free powder Mo/HZSM-5 catalysts.XRD,27Al NMR,SEM,BET and NH3-TPD characterizations of all the catalysts show that the zeolites in the two binder-added catalysts are comparable to those in the three binder-free powder catalysts in crystallinity,crystal size,micropore volume and Brnsted acidity.The test results,on the other hand,show that the catalytic performances of the two binder-added catalysts are worse than those of the four binder-free catalysts on both catalyst mass and zeolite mass bases.Then,TPO and BET measurements of all spent samples were conducted to get a deep insight into the negative effects of binder addition, and the results suggest that the binder additives functioned mainly to enhance the polyaromatization of formed aromatics to coke on their external surfaces and consequently lower the benzene formation activity and selectivity of the catalyst. | Yuebing Xu Hongtao Ma Yo Yamamoto Yoshizo Suzuki Zhanguo Zhang | 2012 | Journal of Natural Gas Chemistry2012，21，6： | 7 |
| 8 | Chemical Stability, Ionic Conductivity of BaCe0.9-xZrxSm0.10O3-α and Its Application to Ammonia Synthesis at Atmospheric Pressure显示文摘稠密的陶器的样品 BaCe0.9 ? xZrxSm0.10O3?(x=0.10, 0.15, 0.20, 0.30 ) 被获得由对待热从一条一起沉淀线路准备的先锋。阶段结构,化学稳定性和陶器的样品的传导行为被 X 光检查粉末衍射和交流电阻抗光谱学方法调查了。所有陶器的样品显示了斜方晶的 perovskite 的一个单个阶段。在暴露了到流动以后,有 x0.20 的样品是相对稳定的混合气体:在为 12 h 的 873 K 的 CO2 +H2O+N2。在测试的样品之中,有 x=0.20 的样品展出了足够的电导率和更好化学的稳定性。为到在湿氢空气的传导的 x=0.20 样品的不同控告的种类的贡献借助于煤气的集中细胞被调查。x=0.20 的样品是,这被发现几乎,一个纯离子的售票员,和离子的传导被氧化物离子主要被质子并且部分在 7731073 K 在湿氢空气贡献。在在一个电解房间的气压的氨合成成功地基于 x=0.20 的样品被进行,山峰氨形成率完成了 2.67 楴湯污搠獥杩 ? 潴椠敤瑮晩 ? 敮 ? 楨? 潣灭畯摮。 | Wang, Xiaowen Yin, Jinling XU, Jianhong Wang, Hongtao Ma, Guilin | 2011 | Chinese Journal of Chemistry2011，29，6： | 4 |
| 9 | New bolting structure of fractured roof based on the Bossinesq equations显示文摘Present support theories contain a number of shortcomings in the designation of fractured roof bolt parameters of rectangular or trapezoidal coal roadways.Roof fall accidents occur easily in this kind of roadway.Based on the Bossinesq equations and the Mohr strength theory,we propose a theory of an anchored cluster structure for fractured roofs and have investigated the formation of such an anchored cluster structure,its self stability mechanism and mechanical properties.The results show that an anchor and the surrounding fractured rock can form a string-like supporting structure,referred to as the structure of an anchored cluster for rational bolt parameters.Not only can the structure maintain its own stability,but as well undertake the load of the overlying strata.The designated support parameters,based on anchored cluster theory can overcome the shortcomings of other support theories applied to a fractured roof of rectangular roadways or could not be calculated.Our anchored cluster theory can provide a theoretical basis for the design of support for rectangular fractured roofs.Furthermore,the theory will help to reduce the probability of roof fall accidents caused by local fractured rock blocks,which can destroy a supporting structure. | LIU, Hongtao MA, Nianjie ZHAO, Feihu LIU, Fengming | 2010 | Mining Science and Technology2010，20，2： | 4 |
| 10 | Development of highly active coated monolith SCR catalyst with strong abrasion resistance for low-temperature application显示文摘与 V 2 O 5-WO3/TiO2 被改变文件夹和涂层厚度准备。与独块巨石作比较与 100% V 2 O 5-WO3/TiO2 粉末,有 260 的催化剂涂层层的涂的独块巨石吗? | Lina GAN Shan LEI Jian YU Hongtao MA Yo YAMAMOTO Yoshizo SUZUKI Guangwen XU Zhanguo ZHANG | 2015 | Frontiers of Environmental Science & Engineering2015，9，6： | 4 |
| 11 | A High-Assurance Trust Model for Digital Community Control System Based on Internet of Things显示文摘Security issues and Internet of Things(IoT) become indispensable part in digital community as IoT develops with the pervasive introduction of additional 'smart' sensors and devices over the last decades, and it necessitates the implementation of information security principle in digital community system. A three-level criticality model to determine the potential impact is proposed in digital community system when various devices lost in this paper. Combining the actual security requirement of digital community and characteristics of IoT, a hierarchical security architecture including defense-in-deep cybersecurity and distribute secure control is proposed. A high-assurance trust model, which assumes insider compromise, which exists in the digital community, is finally proposed according to the security issues analysis. | LI Hongtao XING Jinsheng MA Jianfeng | 2016 | Wuhan University Journal of Natural Sciences2016，21，1： | 4 |
| 12 | Great progress in developing 500 MHz single cell superconducting cavity in China显示文摘Superconducting cavities have been adopted in many kinds of accelerator facilities such as synchrotron radiation light source, hard X-ray free electron laser linac, colliders and energy recovery linacs (ERL). The 500 MHz superconducting cavities will be a candidate to be installed in the high current accelerators and high current ERLs for their large beam aperture, low higher order modes impedance and high current threshold value. This paper presents great progress in the whole sequence of developing 500 MHz superconducting cavity in China. It describes the first in-house successful development of 500 MHz single cell superconducting cavity including the deep-drawing of niobium half cells, electron beam wielding of cavity, surface preparations and vertical testing. The highest accelerating gradient of the fabricated cavity #SCD-02 higher than 10 MV/m was obtained while the quality factor was better than 4×108 at 4.2 K, which has reached the world level of the same kind of cavities. | LIU JianFei HOU HongTao MAO DongQing FENG ZiQiang MA ZhenYu LUO Chen ZHAO ShenJie ZHAO YuBin YU HaiBo YIN Bo ZHANG ZhiGang ZHENG Xiang LI Zheng | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 4 |
| 13 | A privacy-preserving data collection model for digital community显示文摘The widespread use of mobile devices in digital community has promoted the variety of data collecting methods.However,the privacy of individuals plays an important role in data processing or data transmission,and such information should be protected.In this paper,(α,k)-anonymity model,a widely used privacy-preserving model,is adopted as a security frame.Then,a privacy-preserving data collection model((α,k))-CM based on(α,k)-anonymity is proposed and the threat model is analyzed.To resist the possible attack,we propose a generalization-encryption method to achieve a desired privacy level in(α,k)-CM.Generalization can decrease the data size and save the resource might induce information loss in data process;while encryption can decrease information loss,however,it can cause the waste of resource.Generalization-encryption method dynamically encrypts a portion of the data with maximum information loss and adjusts the portion to balance the trade-off metric in the process of generalization.Experimental results and theoretical analysis show that this method is effective in terms of privacy levels and data quality with low resource consumption. | LI HongTao MA JianFeng FU Shuai | 2015 | Science China(Information Sciences)2015，58，3： | 4 |
| 14 | Massive Power Device Condition Monitoring Data Feature Extraction and Clustering Analysis using MapReduce and Graph Model显示文摘Effective storage,processing and analyzing of power device condition monitoring data faces enormous challenges.A framework is proposed that can support both MapReduce and Graph for massive monitoring data analysis at the same time based on Aliyun DTplus platform.First,power device condition monitoring data storage based on MaxCompute table and parallel permutation entropy feature extraction based on MaxCompute MapReduce are designed and implemented on DTplus platform.Then,Graph based k-means algorithm is implemented and used for massive condition monitoring data clustering analysis.Finally,performance tests are performed to compare the execution time between serial program and parallel program.Performance is analyzed from CPU cores consumption,memory utilization and parallel granularity.Experimental results show that the designed framework and parallel algorithms can efficiently process massive power device condition monitoring data. | Hongtao Shen Peng Tao Pei Zhao Hao Ma | 2019 | CES Transactions on Electrical Machines and Systems2019，3，2： | 3 |
| 15 | Evaluation of aquatic rehabilitation technologies for polluted urban rivers and the case study of the Foshan Channel显示文摘An index system for evaluation of technologies for urban river rehabilitation was proposed and discussed.The index system includes indicators of cost,resources,environmental improvement,and social effects.The calculation method for an objective value of each index based on its attributes and weights was presented.The Foshan Channel,which is a seriously polluted,black and malodorous urban river in Foshan City,China,was selected as a case study.The values of the attributes and the weights of the indices for the Foshan Channel were determined.The technologies for the rehabilitation of the Foshan Channel were evaluated based on this index system.Finally,a rehabilitation scheme for the Foshan Channel was proposed. | Haifeng JIA Nan DONG Hongtao MA | 2010 | Frontiers of Environmental Science & Engineering2010，4，2： | 3 |
| 16 | Fast approximate matching of binary codes with distinctive bits显示文摘 | Chenggang Clarence YAN Hongtao XIE Bing ZHANG Yanping MA Qiong DAI Yizhi LIU | 2015 | Frontiers of Computer Science2015，9，5： | 3 |
| 17 | Immune responses of a designed HIV-1 DNA vaccine on rhesus monkeys显示文摘An effective HIV-1 vaccine will be the ultimate solution for the prevention of HIV/AIDS, though HAART plays important roles in treating the disease. In this study, a large-scale recombinant DNA plasmid containing a designed HIV-1 multi-epitope- p24 chimeric gene was prepared and purified. Rhesus monkeys were then inoculated muscularly with the plasmid for four times in week 0, 4, 8 and 18. Whole blood was collected two weeks after the third and fourth inoculation, followed by serum and pe- ripheral blood mononuclear cell (PBMC) separation. The CTL activity and proliferation of PBMCs stimu- lated by macaque MHC-I-restricted HIV-1 CTL epi- tope peptide were analyzed by MTT and LDH release assay, respectively. Th1 cytokines in supernatant of cultured PBMC stimulated by HIV-1 CTL epitope peptide and anti-HIV-1 antibody in serum were as- sayed by ELISA. The results showed that increased CTL target-killing activity, higher secretion of Th1 cytokines (IFN-γ and IL-2) and promoted proliferative reaction of monkey PBMCs stimulated by HIV-1 CTL epitope peptide were detected in the immunization group inoculated by the recombinant DNA vaccine for three times, which were further enhanced by the fourth inoculation. At the same time, HIV-1 specific antibody in serum of immunized monkeys was higher than that in controls. We concluded that the designedHIV-1 DNA vaccine may induce HIV-1 specific cellular and humoral immunity on monkeys. | ZHANG Lishu JIN Ningyi SONG Yingjin SUN Yansong WANG Hong ZHAN Dawei MA Hewen SHANG Yupu JIN Hongtao HONG Baoqing LI Chang | 2006 | Chinese Science Bulletin2006，51，13： | 3 |
| 18 | From unusual suspect to serial killer: Cyanotoxins boosted by climate change may jeopardize megafauna显示文摘The recent mass mortality event of more than 330 African elephants in Botswana has been attributed to biotoxins produced by cyanobacteria;however,scientific evidence for this is lacking.Here,by synthesizing multiple sources of data,we show that,during the past decades,the widespread hypertrophic waters in Southern Africa have entailed an extremely high risk and frequent exposure of cyanotoxins to the wildlife within this area,which functions as a hotspot of mammal species richness.The hot and dry climatic extremes have most likely acted as the primary trigger of the recent and perhaps also of prehistoric mass mortality events.As such climate extremes are projected to become more frequent in Southern Africa in the near future,there is a risk that similar tragedies may take place,rendering African megafauna species,especially those that are already endangered,in risk of extinction.Moreover,cyanotoxin poisoning amplified by climate change may have unexpected cascading effects on human societies.Seen within this perspective,the tragic mass death of the world's largest terrestrial mammal species serves as an alarming early warning signal of future environmental catastrophes in Southern Africa.We suggest that systematic,quantitative cyanotoxin risk assessments are made and precautionary actions to mitigate the risks are taken without hesitation to ensure the health and sustainability of the megafauna and human societies within the region. | Haijun Wang Chi Xu Ying Liu Erik Jeppesen Jens-Christian Svenning Jianguo Wu Wenxia Zhang Tianjun Zhou Puze Wang Shingirai Nangombe Jinge Ma Hongtao Duan Jingyun Fang Ping Xie | 2021 | The Innovation2021，2，2： | 3 |
| 19 | Precise robust motion control of cell puncture mechanism driven by piezoelectric actuators with fractional-order nonsingular terminal slidingmode control显示文摘A novel robust controller is proposed in this study to realize the precise motion control of a cell puncture mechanism(CPM)driven by piezoelectric ceramics(PEAs).The entire dynamic model of CPM is constructed based on the Bouc–Wen model,and the nonlinear part of the dynamic model is optimized locally to facilitate the construction of a robust controller.A model-based,nonlinear robust controller is constructed using time-delay estimation(TDE)and fractional-order nonsingular terminal sliding mode(FONTSM).The proposed controller does not require prior knowledge of unknown disturbances due to its real-time online estimation and compensation of unknown terms by using the TDE technology.The controller also has finite-time convergence and high-precision trajectory tracking capabilities due to FONTSM manifold and fast terminal sliding mode-type reaching law.The stability of the closed-loop system is proved by Lyapunov stability theory.Computer simulation and hardware-in-loop simulation experiments of CPM verify that the proposed controller outperforms traditional terminal sliding mode controllers,such as the integer-order or model-free controller.The proposed controller can also continuously output without chattering and has high control accuracy.Zebrafish embryo is used as a verification target to complete the cell puncture experiment.From the engineering application perspective,the proposed control strategy can be effectively applied in a PEA-driven CPM. | Shengdong Yu Hongtao Wu Mingyang Xie Haiping Lin Jinyu Ma | 2020 | Bio-Design and Manufacturing2020，3，4： | 2 |
| 20 | Reflections on the Catastrophic 2020 Yangtze River Basin Flooding in Southern China显示文摘During the summer of 2020,southern China suffered from catastrophic flooding,the massive basin flood mainly occurred in the Yangtze River's middle and lower reaches.As of July 20,2020,the cumulative precipitation since the rain season started exceeded 500 mm over most of the Yangtze River Basin,reaching>1,200 mm in some areas of the lower reaches,exceeding the same period in 1998,the severest flood year in the past 60 years.Several water gauge stations at Poyang Lake and Chaohu Lake exceeded their historical record values.The water levels in the Wuhan section of the Yangtze River were among the highest ever recorded.As of July 22,2020,45.5 million people had been affected by the floods,with 142 people having died or were missing,and the direct economic losses expected to be around 116 billion RMB(~16.5 billion US dollars).However,the losses from this flood are much lower than those of previous major floods.For example,the catastrophic 1998 flooding led to 1,526 deaths and economic losses of 255 billion RMB(~36.4 billion US dollars).The reasons behind this are worthy of further study and discussion,and may be used for reference in the future and for other countries. | Ke Wei Chaojun Ouyang Hongtao Duan Yunliang Li Mingxing Chen Jiao Ma Huicong An Shu Zhou | 2020 | The Innovation2020，1，2： | 2 |
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