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| 1 | The expressions of Bcl-2 and Bax in gastric carcinoma and precancerous lesions显示文摘Objective: To study the expressions of Bcl-2 and Bax proteins and explore the relationships between them and apoptosis in gastric carcinoma and precancerous lesions. Methods: TUNEL method was used to detect apoptosis and im- munohistochemical staining method was used to detect the expressions of Bcl-2 and Bax proteins in 70 cases of chronic gastritis, 49 cases of intestinal metaplasia, 64 cases of dysplasia and 81 cases of gastric carcinoma. Results: The positive incidences of Bcl-2 and Bax were the highest in severe dysplasia. In intestinal metaplasia and dysplasia, positive incidences of Bcl-2 and Bax were higher than those in chronic gastritis and gastric carcinoma. During the process of evolvement from chronic gastritis to intestinal metaplasia then to dysplasia, apoptosis indexes gradually rise up to mid-high dysplasia, which reached the highest point, then it began to fall down, when it reached the lowest point in gastric carcinoma. There were nega- tive correlations between the expressions of Bcl-2, Bax proteins and apoptosis. Conclusion: The expression of Bcl-2 may be an early behavior in the gastric carcinogenesis. Bax had antagonistic effect to Bcl-2. Detections of Bcl-2 and Bax may be beneficial to the early diagnosis of gastric tumor and precancerous lesions. | Xinhao Yi Qisong Wu Huahui Li Jianmin Wu | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，1： | 3 |
| 2 | Anti-Jamming Message- Driven Frequency Hopping: Part I-System Design 显示文摘 | Zhang Lei Wang Huahui Li Tongtong | 2013 | IEEE Transactions on Wireless Communications2013，2，1： | 1 |
| 3 | Investigating teacher-supported peer assess- ment for EFL writing显示文摘 | Huahui Zhao | 2014 | ELT Journal2014，68，4： | 1 |
| 4 | Erosin-corrosion of thermal sprayed nylon coatings显示文摘 | Huahui Chen Huiyou Zhao Jinxin Qu | 1999 | Wear1999，，222225： | 1 |
| 5 | Microstructure and phase transformation of WC/Ni60B laser cladding coatings during dry sliding wear 显示文摘 | Huahui Chen Caiyun Xu Jun Chen | 2008 | Wear2008，264，78： | 1 |
| 6 | Preparation surface modification and microwave characterization of magnetic iron fibers显示文摘 | Nie Yan He Huahui Zhao Zhenshen | 2006 | J Magn Magn Mater2006，306，1： | 1 |
| 7 | Effect of constant compressive stress induced by imitating tuina stimulation with various durations on the cell cycle,cellular secretion,apoptosis,and expression of myogenic differentiation and myogenic factor 5 of rat skeletal muscle cells in vitro显示文摘OBJECTIVE:To investigate the effect of constant compressive stress induced by imitating Tuina stimulation with various durations on the cell cycle,cellular secretion,apoptosis,and expression of myogenic regulatory factors(MRFs),myogenic factor 5(Myf5)and myogenic differentiation(MyoD)of rat skeletal muscle cells(RSkMCs)in vitro.METHODS:Third passage RSkMCs were subjected to constant compressive stresses with various durations at 2000μstrain for 15,30,60,90,and 120 min via a four-point bending system.The control group(CG)was cultured in the absence of mechanical loading.Alterations of the cell cycle and apoptosis rate were detected by flow cytometry(FCM).The concentrations of interleukin 6(IL-6)/prostaglandin E2(PGE2)and nitric oxide(NO)in supernatants were determined by enzyme-linked immunosorbent assays and the nitrate reductase method,respectively.Expression of Myf5 and MyoD was detected by immunohistochemistry.RESULTS:Compared with the CG,a significant alteration was observed in the synthesis phase fraction(SPF)(P<0.01).The SPF and proliferation index(PI)were reduced from 15 to 90 min,but reached levels similar to those at 120 min.Apoptosis was increased significantly at 30 min(P<0.05)and especially at 90 and 120 min(P<0.01).Expression of MyoD and Myf5 was increased significantly at 15,30,and 90 min(P<0.01).Compared with 15 and 30 min,MyoD and Myf5 expression at 60 and 120 min was decreased significantly(P<0.01).Compared with 60 min,M yoD expression at 90 min was increased significantly(P<0.05),whereas MyoD and Myf5 expression at 120 min was significantly lower(P<0.05).The IL-6 concentration was increased at 60 min compared with the CG and 15 min(P<0.05),whereas the concentrations of PGE2 and NO were the highest at 15 and 30 min,respectively,compared with the CG and other time points(P<0.05).CONCLUSION:The cell cycle,secretion,apoptosis,and Myf5 and MyoD expression of RSkMCs were regulated by compressive stress in a time-dependent manner.SPF and PI were inhibited at short durations(<90 min),but NO and PGE2 secretion was the highest at shorter durations(<30 min).With the prolongation of stimulation time,SPF,PI,and apoptosis were increased,but Myf5 and MyoD expression was decreased gradually at 15-30 min. | Lu Qunwen Su Chengguo Liu Huahui Luo Caigui Yan Bohua | 2020 | Journal of Traditional Chinese Medicine2020，40，4： | 1 |
| 8 | Investigating learners’ use and understanding of peer and teacher feedback on writing: A comparative study in a Chinese English writing classroom显示文摘 | Huahui Zhao | 2010 | Assessing Writing2010，，1： | 1 |
| 9 | Preparation and Microwave Characteristics of Magnetic Iron Fibers显示文摘 | Mingzhong Wu Zhensheng Zhao Huahui He | 2000 | Journal of Magnetism and Magnetic Materials2000，217，： | 1 |
| 10 | Erosion-corrosion of thermal sprayed nylon coatings 显示文摘 | Chen Huahui Zhao Huiyou Qu Jinxin | 1999 | Wear1999，，223225： | 1 |
| 11 | Hybrid ALOHA:a novel MAC protocol显示文摘 | WANG Huahui LI Tongtong | 2007 | IEEE Transactions on Signal Processing2007，55，12： | 1 |
| 12 | Microstructure and phase transformation of WC/Ni60B laser cladding coatings during dry sliding wear 显示文摘 | Chen Huahui Xua Caiyun Chen Jun | 2008 | Wear2008，264，78： | 1 |
| 13 | 肿瘤坏死因子α致肝细胞凋亡效应及其机制的研究(英文)显示文摘Objective: To investigate the apoptosis effect of TNF-α on HepG2 cells and its mechanism in vitro. Methods: HepG2 cells were treated with TNF-α (400 U/mL). HepG2 cells treated with TNF-α for 24 h and apoptosis was proved by DNA fragments on gel electrophoresis. Fluorescent quantitative real-time PCR was used to detect Fas and FasL expression. HepG2 cells treated by TNF-α were co-cultivated with normal HepG2 cells. Apoptosis of HepG2 cells was determined by the method of FACS. Results: After 24 h TNF-α treatment, DNA was collapsed into fragments to form DNA ladder in gel elec- trophoresis; FasL expression increases and induces HepG2 cells apoptosis. By FACS, 98.4% of the co-cultivated cells were apoptosis, but 16.5% cells in control group were apoptosis. Conclusion: TNF-α can induce apoptosis of HepG2 cells in vitro. FasL expression on TNF-α pre-treated HepG2 cells increased and these cells can lead normal HepG2 cells to apoptosis. This may attribute to the cure of virus hepatitis and hepatoma. | Weiqing Song Weihong Lu Huabo Chen Huahui Li Jianmin Wu | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，2： | 1 |
| 14 | Carbon nanotube toughened aluminium oxide nanocomposite显示文摘 | Iftikhar Ahmad Hongzhi Cao Huahui Chen Huiyou Zhao Andrew Kennedy Yan Qiu Zhu | 2009 | Journal of the European Ceramic Society2009，，4： | 1 |
| 15 | Erosion-corrosion of thermal sprayed nylon coatings显示文摘 | Chen Huahui Zhao Huiyou Qu Jinxin | 1999 | Wear1999，，223225： | 1 |
| 16 | An embedded co - processor for accelera- ting window joins over uncertain data streams 显示文摘 | Jiangbo Qian Youming Li Yongll Wang Huahui Chen Yihong Dong | 2012 | Mi- croprocessors and Mierosystems Volume 36 Issue 6 August 20122012，，： | 1 |
| 17 | 显示文摘 | Yan Niea He Huahui | 2006 | Journal of Magnetism and Magnetic Materials2006，，02： | 1 |
| 18 | Anti-JammingMessage- Driven Frequency Hopping: Part I - SystemDesign显示文摘 | Zhang Lei Wang Huahui Li Tongtong | 2013 | IEEE Transactions on Wireless Communi-cations2013，2，1： | 1 |
| 19 | Modifiedverticalbridgmanmethodforgrowthofhigh-qualityCd1-xZnxTecrystals显示文摘 | LiGuoqiang ZhangXiaolu HuaHui etal | 2005 | J Elec ton Maer2005，34，9： | 1 |
| 20 | Simulation and de- sign for stratified iron fiber absorbing materials 显示文摘 | Yu X Zhang X Huahui L | 2002 | Materials & design2002，23，1： | 1 |
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