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| 1 | Development of "Purple Endosperm Rice" by Engineering Anthocyanin Biosynthesis in the Endosperm with a High-Efficiency Transgene Stacking System显示文摘Anthocyanins 在主食庄稼的 anthocyanin 生合成的高抗氧化剂活动,和工程例如米饭(Oryza sativa L.) ,能为改进人的健康提供支持健康的食物。然而,为 biofortification 设计新陈代谢的小径仍然保持困难,并且因为它的 biosynthetic 小径的复杂基因规章的网络,在米饭内乳设计 anthocyanin 生产的以前的尝试失败了。在这研究,我们为叠的 transgene 开发了一个高效率的向量系统并且使用了它在米饭内乳设计 anthocyanin 生合成。我们做了包含内乳特定的倡导者驾驶的八 anthocyanin 相关的基因(从从薄荷科植物的玉米和六结构的基因 ?的二规章的基因) 的构造,加为标记切除的一个可选的标记和基因。有这构造的米饭的转变产生了新奇 biofortified germplasm 紫色内乳瑞斯(用汉语的叫的 Zijingmi ) ,它在内乳有高 anthocyanin 内容和抗氧化剂活动。这 anthocyanin 生产源于 transgenes 和产生激活的表示(或改进) 13 内长的 anthocyanin 生合成基因的表示,那是 silenced 或在野类型的米饭内乳在底层表示。这研究为叠的 transgene 提供一个有效、万用的工具箱并且为一条复杂生物小径的成功的工程表明它的使用,建议为在工厂的农学的特点的合成生物学和改进的这个工具箱的潜在的用途。 | Qinlong Zhu Suize Yu Dongchang Zeng Hongmei Liu Huicong Wang Zhongtang Yang Xianrong Xie Rongxin Shen Jiantao Tan Heying Li Xiucai Zhao Qunyu Zhang Yuanling Chen Jingxing Guo Letian Chen Yao-Guang Liu | 2017 | Molecular Plant2017，10，7： | 47 |
| 2 | 2D MOF Nanoflake-Assembled Spherical Microstructures for Enhanced Supercapacitor and Electrocatalysis Performances显示文摘Metal–organic frameworks(MOFs) are of great interest as potential electrochemically active materials.However, few studies have been conducted into understanding whether control of the shape and components of MOFs can optimize their electrochemical performances due to the rational realization of their shapes. Component control of MOFs remains a significant challenge. Herein, we demonstrate a solvothermal method to realize nanostructure engineering of 2D nanoflake MOFs. The hollow structures withNi/Co-and Ni-MOF(denoted as Ni/Co-MOF nanoflakes and Ni-MOF nanoflakes) were assembled for their electrochemical performance optimizations in supercapacitors and in the oxygen reduction reaction(ORR). As a result, the Ni/CoMOF nanoflakes exhibited remarkably enhanced performance with a specific capacitance of 530.4 F g^(-1)at 0.5 A g^(-1)in1 M LiO H aqueous solution, much higher than that of NiMOF(306.8 F g^(-1)) and ZIF-67(168.3 F g^(-1)), a good rate capability, and a robust cycling performance with no capacity fading after 2000 cycles. Ni/Co-MOF nanoflakes also showed improved electrocatalytic performance for the ORR compared to Ni-MOF and ZIF-67. The present work highlights the significant role of tuning 2D nanoflake ensembles of Ni/Co-MOF in accelerating electron and charge transportation for optimizing energy storage and conversion devices. | Huicong Xia Jianan Zhang Zhao Yang Shiyu Guo Shihui Guo Qun Xu | 2017 | Nano-Micro Letters2017，9，4： | 14 |
| 3 | Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy显示文摘Hyaluronic acid(HA) is a natural ligand of tumor-targeted drug delivery systems(DDS) due to the relevant CD44 receptor overexpressed on tumor cell membranes. However, other HA receptors(HARE and LYVE-1) are also overexpressing in the reticuloendothelial system(RES). Therefore,polyethylene glycol(PEG) modification of HA-based DDS is necessary to reduce RES capture.Unfortunately, pegylation remarkably inhibits tumor cellular uptake and endosomal escapement,significantly compromising the in vivo antitumor efficacy. Herein, we developed a Dox-loaded HA-based transformable supramolecular nanoplatform(Dox/HCVBP) to overcome this dilemma. Dox/HCVBP contains a tumor extracellular acidity-sensitive detachable PEG shell achieved by a benzoic imine linkage.The in vitro and in vivo investigations further demonstrated that Dox/HCVBP could be in a 'stealth' state at blood stream for a long circulation time due to the buried HA ligands and the minimized nonspecific interaction by PEG shell. However, it could transform into a 'recognition' state under the tumor acidic microenvironment for efficient tumor cellular uptake due to the direct exposure of active targeting ligand HA following PEG shell detachment. Such a transformative concept provides a promising strategy to resolve the dilemma of natural ligand-based DDS with conflicting two processes of tumor cellular uptake and in vivo nonspecific biodistribution. | Lu Zhong Lu Xu Yanying Liu Qingsong Li Dongyang Zhao Zhenbao Li Huicong Zhang Haotian Zhang Qiming Kan Yongjun Wang Jin Sun Zhonggui He | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 7 |
| 4 | An epidermal sEMG tattoo-like patch as a new human–machine interface for patients with loss of voice显示文摘Throat cancer treatment involves surgical removal of the tumor,leaving patients with facial disfigurement as well as temporary or permanent loss of voice.Surface electromyography(sEMG)generated from the jaw contains lots of voice information.However,it is difficult to record because of not only the weakness of the signals but also the steep skin curvature.This paper demonstrates the design of an imperceptible,flexible epidermal sEMG tattoo-like patch with the thickness of less than 10μm and peeling strength of larger than 1N cm−1 that exhibits large adhesiveness to complex biological surfaces and is thus capable of sEMG recording for silent speech recognition.When a tester speaks silently,the patch shows excellent performance in recording the sEMG signals from three muscle channels and recognizing those frequently used instructions with high accuracy by using the wavelet decomposition and pattern recognization.The average accuracy of action instructions can reach up to 89.04%,and the average accuracy of emotion instructions is as high as 92.33%.To demonstrate the functionality of tattoo-like patches as a new human–machine interface(HMI)for patients with loss of voice,the intelligent silent speech recognition,voice synthesis,and virtual interaction have been implemented,which are of great importance in helping these patients communicate with people and make life more enjoyable. | Huicong Liu Wei Dong Yunfei Li Fanqi Li Jiangjun Geng Minglu Zhu Tao Chen Hongmiao Zhang Lining Sun Chengkuo Lee | 2020 | Microsystems & Nanoengineering2020，6，1： | 6 |
| 5 | A fully automatic registration approach based on contour and SIFT for HJ-1 images显示文摘To achieve a fully automatic registration between HJ-1 CCD images and HJ-1 infrared images is a difficult task as it must deal with the varying illuminations and resolutions of the images,different perspectives,and the local deformations within the images.In this paper,aimed at those registration issues,a fully automatic registration approach based on contour and SIFT is proposed.The registration technique performs a pre-registration process using contour feature matching algorithm that decides the overlapping region between a reference image and an input image.Once the coarse regions are obtained,it performs a fine registration process based on SIFT detector and a local adaptive matching strategy.In the fine registration process,image blocking theory is used,which not only speeds up the features extraction and matching,but also makes the matching point pairs distributed uniformly in images,and further improves the accuracy of input image rectification.Experiments with visible images and infrared images from HJ-1A/B demonstrate the efficiency and the accuracy of the proposed technique for multisource remote sensing images registration. | NI XiLiang CAO ChunXiang DING Lin JIANG Tao ZHANG Hao JIA HuiCong LI GuangHe ZHAO Jian CHEN Wei JI Wei XU Min GAO MengXu ZHENG Sheng TIAN Rong LIU Cheng LI Sha | 2012 | Science China Earth Sciences2012，55，10： | 5 |
| 6 | Recent Progress on Two-Dimensional Nanoflake Ensembles for Energy Storage Applications显示文摘The rational design and synthesis of two-dimensional(2D) nanoflake ensemble-based materials have garnered great attention owing to the properties of the components of these materials, such as high mechanical flexibility, high specific surface area, numerous active sites,chemical stability, and superior electrical and thermal conductivity. These properties render the 2D ensembles great choices as alternative electrode materials for electrochemical energy storage systems. More recently,recognition of the numerous advantages of these 2D ensemble structures has led to the realization that the performance of certain devices could be significantly enhanced by utilizing three-dimensional(3D) architectures that can furnish an increased number of active sites. The present review summarizes the recent progress in 2D ensemble-based materials for energy storage applications,including supercapacitors, lithium-ion batteries, and sodium-ion batteries. Further, perspectives relating to the challenges and opportunities in this promising research area are discussed. | Huicong Xia Qun Xu Jianan Zhang | 2018 | Nano-Micro Letters2018，10，4： | 4 |
| 7 | Stress Effects of Chlorate on Longan(Dimocarpus longan Lour.)Trees: Changes in Nitrogen and Carbon Nutrition显示文摘Three-year-old potted longan(Dimocarpus longan Lour.cv.Shixia)trees were treated with potassium chlorate and effects on nitrogen and carbon nutrition were examined.The results showed that potassium chlorate at 10 and 20 g per pot failed to induce flower but suppressed shoot growth and caused leaf chlorosis and drop.The treatment significantly inhibited nitrate reductase but increased nitrogen concentration in the leaves and buds.Concentration of soluble amino acids in the leaves of treated trees increased within 14 days and then declined to the control level,while it increased constantly in buds.In both organs,the amino acid increase was an all-round one,with all the tested 21 amino acids increased.However,soluble proteins in the leaves were slightly increased by chlorate,indicating that de novo synthesis of amino acids was activated.Chlorate reduced photosynthetic rate and stomatal conductance but slightly increased CO2 concentration in the mesophyll,suggesting that chlorate treatment damaged photosynthetic apparatus.The damage was reflected by the destruction of thylakoids and grana in the chloroplasts.Chlorate also caused depletion of starch with significant accumulation of soluble sugars in the leaves.Accumulation of sugars and soluble amino acids indicates osmotic adjustment in response to the stress caused by chlorate treatment. | LU Jiemei YANG Ruitao WANG Huicong HUANG Xuming | 2017 | Horticultural Plant Journal2017，3，6： | 4 |
| 8 | Fabrication of Fe-doped Co-MOF with mesoporous structure for the optimization of supercapacitor performances显示文摘The synergy effect between different components has attracted widespread attentions because of improved activity, selectivity and stability than single component. In this paper, we fabricated mesoporous hybrid dual-metal Co and Fe containing metallic organic framework(Co/Fe-MOF), Fe-MOF,and Co-MOF in the ionic liquid(IL)/supercritical CO2(SC)/surfactant emulsion system, and then studied the electrochemical properties of the three MOFs systematically. Experiment results indicate that, by taking advantages of coexistence of double metal, hybrid bi-metal Co/Fe-MOF exhibits the highest specific capacitance and the best cycling stability, with specific capacitance to 319.5 F/g at 1 A/g, 1.4 and 4 times for single Co-MOF and Fe-MOF, respectively. | Huanan Yu Huicong Xia Jianan Zhang Jing He Shiyu Guo Qun Xu | 2018 | Chinese Chemical Letters2018，29，6： | 4 |
| 9 | Aberrant seed development in Litchi chinensis is associated with the impaired expression of cell wall invertase genes显示文摘Cell wall invertase(CWIN)are known to play important roles in seed development.However,most reports to date have focused on a single gene family member,and have mainly investigated CWIN functions during the filling stage of seed development.In this study,we found significant lower levels of CWIN protein and activity associated with seed abortion in the Litchi chinensis cultivar“Nuomici.”We identified five litchi CWIN genes and observed that the expression of LcCWIN5 was limited to the flower tissues and decreased sharply with fruit development.Silencing of LcCWIN5 expression before 28 DAA(cell division stage)resulted in perturbed liquid endosperm development,smaller seeds,and higher seed abortion rate,while silencing after 28 DAA(filling stage)had no effect on seed development.In contrast,LcCWIN2 was mostly expressed in the funicle and seed coat,and increased with fruit development.Decreased LcCWIN2 expression and CWIN activity during early seed filling coincided with smaller seeds in the cultivar“Feizixiao.”Silencing of LcCWIN2 caused a reduction in the seed size without inducing seed abortion.We propose that CWIN activity in seed maternal tissues during cell division stage is likely due to LcCWIN5 expression,which regulates early seed development.On the other hand,CWIN activity during the filling stage is due to the expression of LcCWIN2,which may promote carbon import by creating a sucrose gradient.Comparable LcCWIN5 expression,but much lower CWIN activity,detected in the funicle of“Nuomici”is consistent with post-translational regulation. | Jieqiong Zhang Zichen Wu Fuchu Hu Lian Liu Xuming Huang Jietang Zhao Huicong Wang | 2018 | Horticulture Research2018，5，1： | 4 |
| 10 | Ecotoxicity of Cadmium to Maize and Soybean Seedling in Black Soil显示文摘Ecotoxicity and bioavailability of cadmium(Cd)to the maize(Zea mays L.)and the soybean(Glycine max(L.)Merr.)were investigated by acute toxicity experiment in the laboratory with black soil.Ecotoxicity and bioavailability of Cd were quantified by calculating the median effective concentration(EC50)and bioaccumulation factor(BAF).The measurement endpoints used were seed germination and seedling growth(shoot and root).The results showed that concentrations of Cd in the soil had adverse effect on the growth of roots and shoots.Seed germination was not the sensitive indicator for the ecotoxicity of Cd in the soil,while the growth of roots was the most sensitive measurement endpoint.Absorbability and transport of Cd in plants depended on the test crop species and Cd concentrations in the soil.The maize retains more Cd in its roots,while the soybean transports more Cd to the shoots from roots. | Cao Huicong Wang Jinda Zhang Xuelin | 2007 | Chinese Geographical Science2007，17，3： | 4 |
| 11 | Defect Engineering on Carbon‑Based Catalysts for Electrocatalytic CO2 Reduction显示文摘Electrocatalytic carbon dioxide(CO2)reduction(ECR)has become one of the main methods to close the broken carbon cycle and temporarily store renewable energy,but there are still some problems such as poor stability,low activity,and selectivity.While the most promising strategy to improve ECR activity is to develop electrocatalysts with low cost,high activity,and long-term stability.Recently,defective carbon-based nanomaterials have attracted extensive attention due to the unbalanced electron distribution and electronic structural distortion caused by the defects on the carbon materials.Here,the present review mainly summarizes the latest research progress of the construction of the diverse types of defects(intrinsic carbon defects,heteroatom doping defects,metal atomic sites,and edges detects)for carbon materials in ECR,and unveil the structure-activity relationship and its catalytic mechanism.The current challenges and opportunities faced by high-performance carbon materials in ECR are discussed,as well as possible future solutions.It can be believed that this review can provide some inspiration for the future of development of high-performance ECR catalysts. | Dongping Xue Huicong Xia Wenfu Yan Jianan Zhang Shichun Mu | 2021 | Nano-Micro Letters2021，13，1： | 4 |
| 12 | Electron-withdrawing functional ligand promotes CO2 reduction catalysis in single atom catalyst显示文摘Electrochemical carbon dioxide reduction reaction (CO2RR) powered by renewable electricity offers an attractive approach to reduce carbon emission and at the same time produce valuable chemicals/fuels.To design efficient CO2 reduction electrocatalyst,it is important to understand the structure-activity relationship.Herein,we design a series of single Co atoms electrocatalysts with well-defined active sites electronic structures,which exhibit outstanding CO2RR activity with controllable selectivity to CO.Experimental and density functional theory (DFT) calculation studies show that introducing nitro (amino) ligand next to single Co atom catalytic center with electron-withdrawing (electron-donating) capability favors (hinders) CO2 reduction catalysis.This work provides an in-depth understanding of how functional ligand affects the splitting of transition metal 3d electron orbital,thereby changing the electron transfer from transition metal active site to CO2,which is closely related to the Gibbs free energy of the rate-determining step (CO2+e^-+*→*CO2^-). | Xinyi Ren Song Liu Huicong Li Jie Ding Linghui Liu Zhichong Kuang Ling Li Hongbin Yang Fuquan Bai Yanqiang Huang Tao Zhang Bin Liu | 2020 | Science China Chemistry2020，63，12： | 3 |
| 13 | Reflections on the Catastrophic 2020 Yangtze River Basin Flooding in Southern China显示文摘During the summer of 2020,southern China suffered from catastrophic flooding,the massive basin flood mainly occurred in the Yangtze River's middle and lower reaches.As of July 20,2020,the cumulative precipitation since the rain season started exceeded 500 mm over most of the Yangtze River Basin,reaching>1,200 mm in some areas of the lower reaches,exceeding the same period in 1998,the severest flood year in the past 60 years.Several water gauge stations at Poyang Lake and Chaohu Lake exceeded their historical record values.The water levels in the Wuhan section of the Yangtze River were among the highest ever recorded.As of July 22,2020,45.5 million people had been affected by the floods,with 142 people having died or were missing,and the direct economic losses expected to be around 116 billion RMB(~16.5 billion US dollars).However,the losses from this flood are much lower than those of previous major floods.For example,the catastrophic 1998 flooding led to 1,526 deaths and economic losses of 255 billion RMB(~36.4 billion US dollars).The reasons behind this are worthy of further study and discussion,and may be used for reference in the future and for other countries. | Ke Wei Chaojun Ouyang Hongtao Duan Yunliang Li Mingxing Chen Jiao Ma Huicong An Shu Zhou | 2020 | The Innovation2020，1，2： | 2 |
| 14 | The roles and activation of endocardial Notch signaling in heart regeneration显示文摘As a highly conserved signaling pathway in metazoans,the Notch pathway plays important roles in embryonic development and tissue regeneration.Recently,cardiac injury and regeneration have become an increasingly popular topic for biomedical research,and Notch signaling has been shown to exert crucial functions during heart regeneration as well.In this review,we briefly summarize the molecular functions of the endocardial Notch pathway in several cardiac injury and stress models.Although there is an increase in appreciating the importance of endocardial Notch signaling in heart regeneration,the mechanism of its activation is not fully understood.This review highlights recent findings on the activation of the endocardial Notch pathway by hemodynamic blood flow change in larval zebrafish ventricle after partial ablation,a process involving primary cilia,mechanosensitive ion channel Trpv4 and mechanosensitive transcription factor Klf2. | Huicong Li Cheng Chang Xueyu Li Ruilin Zhang | 2021 | Cell Regeneration2021，10，1： | 2 |
| 15 | Efficient polysulfide blocker from conductive niobium nitride@graphene for Li-S batteries显示文摘Lithium sulfur batteries are one of the most promising alternative electrochemical systems,but their practical applications are largely hindered by the serious shuttling problems and sluggish redox kinetics.Here,the conductive and polar niobium nitride(NbN)is in-situ introduced onto graphene with ultrasmall size and high dispersion,and their composite is used to construct an efficient lithium polysulfide blocking layer.The graphene helps to construct highly conductive pathways,and niobium nitride serves as the sulfiphilic sites to chemically adsorb the migrating lithium polysulfides and catalyze their redox conversion.Hence,the cells with the Nb N/G interlayers exhibit a long cycle life with a lower capacity decay of 0.096%/cycle at 1 C for 300 cycles and high rate capability of 937 m Ah g^-1 at 2 C.Further coupling with a sulfur/carbon nanofiber electrode,the cell with an ultra-high sulfur loading of 10.8 mg cm^-2 delivers an areal capacity of 12.5 m Ah cm^-2 at 0.1 C. | Huifa Shi Zhenhua Sun Wei Lv Shujie Xiao Huicong Yang Ying Shi Ke Chen Shaogang Wang Bingsen Zhang Quan-Hong Yang Feng Li | 2020 | Journal of Energy Chemistry2020，29，6： | 1 |
| 16 | Resilience to natural hazards: a geographic perspective显示文摘 | Hongjian Zhou Jing’ai Wang Jinhong Wan Huicong Jia | 2010 | Natural Hazards2010，，1： | 1 |
| 17 | Multi-scales Analysis of Driving Forces on Land Use/Cover Change in China:Taking Farmland Returning to Forest or Grassland as a Case显示文摘Increasing populations are causing an increase in food demands, and the area of cultivated land expands every year. Inappropriate land transition from ecology to production results in the constant decline of the ecological security level and influences the regional sustainable development. Adjusting unreasonable land use mode and reconstructing natural land cover are important ways to maintain and improve the ecological environment. Also reclaiming farmland as areas for forests and grasslands (FRFG) is another way. Successful implementation of FRFG in China is the result of comprehensive effect of the multi-scales driving forces. This paper analyses the driving forces of FRFG in China on a national (country) –regional (province) – local (county) – household (farmer) level scale, and the results are: driving forces at the national scale include ecological and food security and the western development of China; at the regional scale, ecological and economic benefits become the main factors to influence the dimension of FRFG under the same policy. The driving forces can be divided into 6 types: industrial structure adjustment, water source protection, flood prevention, the Three-Gorge Project protection, reduction of the amount of sediment flowing into the Yellow River and wind erosion desertification prevention. The driving forces at the local scale can be divided into 12 types with developing leading industries, increasing farmers’ income and improving agricultural production conditions as the main types; at the household scale, the nationalpolicy meeting farmers’ demands and the optimization of individual interests are all driving forces. | Zhou Hongjian Huang Shuling Wang Yuanyuan Wang Jing'ai Jia Huicong | 2006 | Chinese Journal of Population,Resources and Environment2006，4，3： | 1 |
| 18 | Probing the active sites of 2D nanosheets with Fe-N-C carbon shell encapsulated Fe_(x)C/Fe species for boosting sodium-ion storage performances显示文摘Developing stable but high active metal-nitrogen-carbon(M-N-C)-based hard carbon anode is a promising way to be the alternatives to graphene and blank hard carbon for sodium-ion batteries(SIBs),requiring the precise tailoring of the electronic structure for optimizing the Na+intercalation behavior,yet is greatly challenging.Herein,Fe-N-C graphitic layer-encapsulating Fe3C species within hard carbon nanosheets(Fe-N-C/Fe3C@HCNs)are rationally engineered by pyrolysis of self-assembled polymer.Impressively,the Fe-N-C/Fe3C@HCNs exhibit outstanding rate capacity(242 mAh·g^(−1)at 2,000 mA·g^(−1)),which is 2.1 and 4.2 times higher than that of Fe-N-C and N-doped carbon(N-C),respectively,and prolonged cycling stability(176 mAh·g^(−1)at 2,000 mA·g^(−1)after 2,000 cycles).Theoretical calculations unveil that the Fe3C species enhance the electronic transfer from Na to Fe-N-C,resulting in the charge redistribution between the interfaces of Fe3C and Fe-N-C.Thus,the optimized adsorption behavior towards Na+reduces the thermodynamic energy barriers.The synergistic effect of Fe3C and Fe-N-C species maintains the structural integrity of electrode materials during the sodiation/desodiation process.The in-depth insight into the advanced Na+storage mechanisms of Fe3C@Fe-N-C offers precise guidance for the rational establishment of confinement heterostructures in SIBs. | Huicong Xia Pengfei Yuan Lingxing Zan Gan Qu Yunchuan Tu Kaixin Zhu Yifan Wei Zeyu WeiFangying Zheng Mo Zhang Yongfeng Hu Dehui Deng Jianan Zhang | 2022 | Nano Research2022，15，8： | 1 |
| 19 | In situ apolipoprotein E-enriched corona guides dihydroartemisinin-decorating nanoparticles towards LDLr-mediated tumor-homing chemotherapy显示文摘The therapeutic efficiency of active targeting nanoparticulate drug delivery systems(nano-DDS)is highly compromised by the plasma proteins adsorption on nanoparticles(NPs)surface,which significantly hinders cell membrane receptors to recognize the designed ligands,and provokes the off-target toxicity and rapid clearance of NPs in vivo.Herein,we report a novel dihydroartemisinin(DHA)-decorating nano-DDS that in situ specifically recruits endogenous apolipoprotein E(apoE)on the NPs surface.The apoE-anchored corona is able to prolong PLGA-PEG2000-DHA(PPD)NPs circulation capability in blood,facilitate NPs accumulating in tumor cells by the passive enhanced permeability and retention(EPR)effect and low-density lipoprotein receptor(LDLr)-mediated target transport,and ultimately improve the in vivo antitumor activity.Our findings demonstrate that the strategy of in situ regulated apoE-enriched corona ensures NPs an efficient LDLr-mediated tumor-homing chemotherapy. | Zhenbao Li Jiaojiao Zhu Yongqi Wang Mei Zhou Dan Li Shunzhe Zheng LiLi Yin Cong Luo Huicong Zhang Lu Zhong Wei Li JianWang Shuangying Gui Biao Cai Yongjun Wang Jin Sun | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，4： | 1 |
| 20 | District prediction of cholera risk in China based on environmental factors显示文摘The epidemics of cholera are impacted by many climatic and environmental factors such as precipitation, temperature, elevation and so on. The paper analyzed the suitable degree of V. cholerae in China using MaxEnt based on some geographic and climatic factors, and predicted the cholera risk in each district of China according to the suitable degree. The result shows that the areas in coastal southeast, central China and western Sichuan Basin are relatively suitable for V. cholerae and the suitable degree is higher in the Xinjiang Basin than in surrounding areas. The variables of precipitation, temperature and DEM are three main environmental risky factors that affecting the distribution of cholera in China. The variables of relative humidity, the distance to the sea and air pressure also have impacts on cholera, but sunshine duration and drainage density have little impact. The AUC value of MaxEnt based model is above 0.9 which indicates a high accuracy. | XU Min CAO ChunXiang WANG DuoChun KAN Biao JIA HuiCong XU YunFei LI XiaoWen | 2013 | Chinese Science Bulletin2013，58，23： | 1 |
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