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| 1 | Formation mechanism and control methods of acicular ferrite in HSLA steels:A review显示文摘High strength low alloy(HSLA) steels have been widely used in pipelines,power plant components,civil structures and so on,due to their outstanding mechanical properties as high strength and toughness,and excellent weldability.Multi-phase microstructures containing acicular ferrite or acicular ferrite dominated phase have been proved to possess good comprehensive properties in HSLA steels.This paper mainly focuses on the formation mechanisms and control methods of acicular ferrite in HSLA steels.Effect of austenitizing conditions,continuous cooling rate,and isothermal quenching time and temperature on acicular ferrite transformation was reviewed.Furthermore,the modified process to control the formation of multi-phase microstructures containing acicular ferrite,as intercritical heat treatments,step quenching treatments and thermo-mechanical controlled processing,was summarized.The favorable combination of mechanical properties can be achieved by these modified treatments. | Yi Shao Chenxi Liu Zesheng Yan Huijun Li Yongchang Liu | 2018 | Journal of Materials Science & Technology2018，34，5： | 13 |
| 2 | De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome显示文摘 | Yongyi Yuan Jianguo Zhang Qing Chang Jin Zeng Feng Xin Jianjun Wang Qingyan Zhu Jing Wu Jingqiao Lu Weiwei Guo Xukun Yan Hui Jiang Binfei Zhou Qi Li Xue Gao Huijun Yuan Shiming Yang Dongyi Han Zixu Mao Ping Chen Xi Lin Pu Dai | 2014 | Cell Research2014，24，11： | 13 |
| 3 | Graft-accelerated virus-induced gene silencing facilitates functional genomics in rose flowers显示文摘Rose has emerged as a model ornamental plant for studies of flower development, senescence, and morphology, as well as the metabolism of floral fragrances and colors.Virus-induced gene silencing(VIGS) has long been used in functional genomics studies of rose by vacuum infiltration of cuttings or seedlings with an Agrobacterium suspension carrying TRV-derived vectors. However, VIGS in rose flowers remains a challenge because of its low efficiency and long time to establish silencing. Here we present a novel and rapid VIGS method that can be used to analyze gene function in rose,called ‘graft-accelerated VIGS', where axil ary sprouts are cut from the rose plant and vacuum infiltrated with Agrobacterium. The inoculated scions are then grafted back onto the plants to flower and silencing phenotypes can be observed within 5 weeks, post-infiltration. Using this new method, we successfully silenced expression of the RhDFR_1, RhA G, and RhNUDX_1 in rose flowers, and affected their color, petal number, as well as fragrance, respectively. This grafting method will facilitate high-throughput functional analysis of genes in rose flowers. Importantly, it may also be applied to other woody species that are not currently amenable to VIGS by conventional leaf or plantlet/seedling infiltration methods. | Huijun Yan Shaochuan Shi Nan Ma Xiaoqian Cao Hao Zhang Xianqin qiu Qigang Wang Hongying Jian Ningning Zhou Zhao Zhang Kaixue Tang | 2018 | Journal of Integrative Plant Biology2018，60，1： | 11 |
| 4 | Inheritance of Perpetual Blooming in Rosa chinensis ‘Old Blush'显示文摘Perpetual blooming is one of the most important biological and economical traits in modern rose, while the genetic basis underlining the control of this trait is poorly investigated. With an aim in dissecting the genetic determinism of perpetual blooming, we developed six rose populations(OB, W, F1, F2, BC1 OB and BC1W) derived from a WOB population [interspecific diploid hybridization between Rosa chinensis ‘Old Blush'(OB) and R. wichuriana ‘Basye's Thornless'(W)]. Perpetual blooming is absent both in a F1 population with 296 individuals and a BC1 W population(W as the backcross parent) with 150 individuals. However, the perpetual blooming trait showed a typical 3︰1 segregation in a backcross population BC1 OB with OB as the backcross parent. In this population with 300 individuals, 83 plants had the perpetual blooming phenotype while the other 217 featured non-perpetual blooming, indicating that the perpetual blooming trait is very likely controlled by two recessive genes in R. chinensis(rpb1 and rpb2). These genetic data suggest that the inheritance of rose perpetual blooming may be controlled by a complex mechanism. | LI Shubin ZHOU Ningning ZHOU Qing YAN Huijun JIAN Hongying WANG Qigang CHEN Min QIU Xianqin ZHANG Hao WANG Shufang LI Shufa TANG Kaixue | 2015 | Horticultural Plant Journal2015，1，2： | 9 |
| 5 | A detached petal disc assay and virus-induced gene silencing facilitate the study of Botrytis cinerea resistance in rose flowers显示文摘Fresh-cut roses(Rosa hybrida)are one of the most important ornamental crops worldwide,with annual trade in the billions of dollars.Gray mold disease caused by the pathogen Botrytis cinerea is the most serious fungal threat to cut roses,causing extensive postharvest losses.In this study,we optimized a detached petal disc assay(DPDA)for artificial B.cinerea inoculation and quantification of disease symptoms in rose petals.Furthermore,as the identification of rose genes involved in B.cinerea resistance could provide useful genetic and genomic resources,we devised a virusinduced gene silencing(VIGS)procedure for the functional analysis of B.cinerea resistance genes in rose petals.We used RhPR10.1 as a reporter of silencing efficiency and found that the rose cultivar‘Samantha’showed the greatest decrease in RhPR10.1 expression among the cultivars tested.To determine whether jasmonic acid and ethylene are required for B.cinerea resistance in rose petals,we used VIGS to silence the expression of RhLOX5 and RhEIN3(encoding a jasmonic acid biosynthesis pathway protein and an ethylene regulatory protein,respectively)and found that petal susceptibility to B.cinerea was affected.Finally,a VIGS screen of B.cinerea-induced rose transcription factors demonstrated the potential benefits of this method for the high-throughput identification of gene function in B.cinerea resistance.Collectively,our data show that the combination of the DPDA and VIGS is a reliable and highthroughput method for studying B.cinerea resistance in rose. | Xiaoqian Cao Huijun Yan Xintong Liu Dandan Li Mengjie Sui Jie Wu Hongqiang Yu Zhao Zhang | 2019 | Horticulture Research2019，6，1： | 5 |
| 6 | Greenland Ice Sheet Contribution to Future Global Sea Level Rise based on CMIP5 Models显示文摘Sea level rise(SLR) is one of the major socioeconomic risks associated with global warming. Mass losses from the Greenland ice sheet(GrIS) will be partially responsible for future SLR, although there are large uncertainties in modeled climate and ice sheet behavior. We used the ice sheet model SICOPOLIS(SImulation COde for POLythermal Ice Sheets) driven by climate projections from 20 models in the fifth phase of the Coupled Model Intercomparison Project(CMIP5) to estimate the GrIS contribution to global SLR. Based on the outputs of the 20 models, it is estimated that the GrIS will contribute 0–16(0–27) cm to global SLR by 2100 under the Representative Concentration Pathways(RCP) 4.5(RCP 8.5) scenarios. The projected SLR increases further to 7–22(7–33) cm with 2×basal sliding included. In response to the results of the multimodel ensemble mean, the ice sheet model projects a global SLR of 3 cm and 7 cm(10 cm and 13 cm with 2×basal sliding) under the RCP 4.5 and RCP 8.5 scenarios, respectively. In addition, our results suggest that the uncertainty in future sea level projection caused by the large spread in climate projections could be reduced with model-evaluation and the selective use of model outputs. | YAN Qing WANG Huijun Ola M.JOHANNESSEN ZHANG Zhongshi | 2014 | Advances in Atmospheric Sciences2014，31，1： | 5 |
| 7 | Simulation of Greenland ice sheet during the mid-Pliocene warm period显示文摘One of the key uncertainties in future sea-level projections is attributed to the Greenland ice sheet(GrIS).Studying the response of the GrIS to climate changes during the past warm periods is helpful for understanding future changes in the GrIS.In this study,using three global climate models(Community Atmosphere Model version3.1 and version 4.0 and Norwegian Earth System Model)and a three-dimensional ice sheet model,we investigate the climate and ice sheet changes over Greenland during the mid-Pliocene warm period(*3 Ma BP).The results show that the regionally averaged summer temperature over Greenland is 9.4–13.4°C higher during the mid-Pliocene period than during the pre-industrial era and the annual mean precipitation is 65.2–108.3 mm a-1greater.In response to this warm-wet climate,the GrIS shows a substantial decrease in size during the mid-Pliocene,with little ice existing along the eastern coast of Greenland.Compared to that simulated in the control run,the global sea level is approximately 7.8–8.1 m higher during the mid-Pliocene due to the decrease in the size of the GrIS.In addition,paleoclimate proxies also indicate that it is unlikely that a large-scale ice sheet exists over Greenland during the mid-Pliocene warm period. | Qing Yan Zhongshi Zhang Huijun Wang Ran Zhang | 2014 | Chinese Science Bulletin2014，59，2： | 3 |
| 8 | Biodegradation of 3,5-dimethyl-2,4-dichlorophenol in saline wastewater by newly isolated Penicillium sp.yz11-22N2显示文摘In this study,the performance of 3,5-dimethyl-2,4-dichlorophenol(DCMX) degradation by a screened strain was investigated.18 S r DNA and the neighbor-joining method were used for identification of the isolated strain.The results of phylogenetic analysis and scanning electron micrographs showed that the most probable identity of the screened strain should be Penicillium sp.Growth characteristics of Penicillium sp.and degradation processes of DCMX were examined.Fourier transform infrared spectroscopy of the inoculated DCMX solution was recorded,which supported the capacity of DCMX degradation by the screened Penicillium sp.Under different salinity conditions,the highest growth rate and removal efficiency for DCMX were obtained at p H 6.0.The removal efficiency decreased from 100%to 66% when the DCMX concentration increased from 5 to 60 mg/L,respectively.Using a Box–Behnken design,the maximum DCMX removal efficiency was determined to be 98.4%.With acclimation to salinity,higher removal efficiency could be achieved.The results demonstrate that the screened Penicillium sp.has the capability for degradation of DCMX. | Zhou Yan Huijun He Chunping Yang Guangming Zeng Le Luo Panpan Jiao Huiru Li Li Lu | 2017 | Journal of Environmental Sciences2017，29，7： | 3 |
| 9 | Expression and characterization of Kunitz domain 3 and C-terminal of human tissue factor pathway inhibitor-2显示文摘人的织物因素小径 inhibitor-2 (hTFPI-2 ) 是一个丝氨酸朊酶禁止者,它的禁止的活动被肝磷脂提高。Kunitz 领域 3 并且 hTFPI-2 (hTFPI-2/KD3C ) 的 C 终端,向肝磷脂钙举办这项活动,成功地在 Pichia pastoris 被表示了并且由 SP-Sepharose 和 heparin-Sepharose 层析净化了。转变红外线的光谱学(FTIR )(CD ) ,拉曼光谱学,和圆形的二色性试验的 Fourier 结果暗示 hTFPI-2/KD3C 包含了螺旋和 -strand, 的小内容但是大量随机的卷和二种二硫化物契约, gauche-gauche-gauche (ggg ) 和 trans-gauche-trans (tgt ) 。有肝磷脂钙的 hTFPI-2/KD3C 的相互作用被 CD 调查。肝磷脂钙在 hTFPI-2/KD3C 导致了海滨到取决于 hTFPI-2/KD3C 和肝磷脂钙的比率的不同程度,这被发现。 | Lina Zhu Jiping Wang Jingui Mu Huijun Wang Chenqi Zhang Jue Wang Xingang Liu Xiaomin Yan Linsen Dai Duan Ma | 2009 | Acta Biochimica et Biophysica Sinica2009，41，11： | 3 |
| 10 | Influences of anion concentration and valence on dispersion and aggregation of titanium dioxide nanoparticles in aqueous solutions显示文摘Dispersion and aggregation of nanoparticles in aqueous solutions are important factors for safe application of nanoparticles. In this study, dispersion and aggregation of nano-TiO_2 in aqueous solutions containing various anions were investigated. The influences of anion concentration and valence on the aggregation size, zeta potential and aggregation kinetics were individually investigated. Results showed that the zeta potential decreased from 19.8 to-41.4 mV when PO_4^(3-) concentration was increased from 0 to 50 mg/L, while the corresponding average size of nano-TiO_2 particles decreased from 613.2 to 540.3 nm. Both SO_4^(2-) and NO_3^-enhanced aggregation of nano-TiO_2in solution. As SO_4^(2-) concentration was increased from 0 to 500 mg/L, the zeta potential decreased from 19.8 to 1.4 mV, and aggregate sizes increased from 613.2 to 961.3 nm.The trend for NO_3^- fluctuation was similar to that for SO_4^(2-) although the range of variation for NO_3^- was relatively narrow. SO_4^(2-) and NO_3^-accelerated the aggregation rapidly, while PO_4^(3-) did so slowly. These findings facilitate the understanding of aggregation and dispersion mechanisms of nano-TiO_2 in aqueous solutions in the presence of anions of interest. | Huijun He | 2017 | Journal of Environmental Sciences2017，29，4： | 2 |
| 11 | Simulation of sea surface temperature changes in the Middle Pliocene warm period and comparison with reconstructions显示文摘The Middle Pliocene (ca 3.12–2.97 Ma) is a recent warm period in the Earth’s history. In many respects, the warmth of the Middle Pliocene is similar to the probable warm situation of the late 21st century predicted by climate models. Understanding the Middle Pliocene climate is important in predicting the future climate with global warming. Here, we used the latest reconstructions for the Middle Pliocene—Pliocene Research Interpretation and Synoptic Mapping (PRISM) version 3—to simulate the Middle Pliocene climate with a fully coupled model Fast Ocean Atmosphere Model. From comparison of the results of simulations with reconstructions, we considered two important scientific topics of Middle Pliocene climate modeling: extreme warming in the subpolar North Atlantic and a permanent El Ni?o in the tropical Pacific. Our simulations illustrate that the global annual mean sea surface temperature (SST) in the Middle Pliocene was about 2.3°C higher than that in the pre-industrial era. The warming was stronger at midand high latitudes than at low latitudes. The simulated SST changes agree with SST reconstructions in PRISM3 data, especially for the North Atlantic, North Pacific and west coast of South America. However, there were still discrepancies between the simulation of the SST and reconstructions for the subpolar North Atlantic and tropical Pacific. In the case of the Atlantic, the weakened meridional overturning circulation in the simulation did not support the reconstruction of the extremely warm condition in the subpolar North Atlantic. In the case of the tropical Pacific, the whole ocean warmed, especially the eastern tropical Pacific, which did not support the permanent El Ni?o suggested by the reconstruction. From evaluation of the modeling and reconstruction, we suggest that the above discrepancies were due to uncertainties in reconstructions, difficulties in paleoclimate modeling and deficiencies of climate models. The discrepancies should be reduced through consideration of both the modeling and data. | YAN Qing ZHANG ZhongShi WANG HuiJun JIANG DaBang ZHENG WeiPeng | 2011 | Chinese Science Bulletin2011，56，9： | 2 |
| 12 | Decoding algorithms of single photon counting imager based on two-dimensional Vernier anodes显示文摘The decoding algorithms of two-dimensional Vernier anodes are deduced theoretically.The precision of decoding and uniqueness of encoding are proved.The influencing factors of detection sensitivity and spatial resolution are discussed.The single photon imaging system is constructed,and the two-dimensional Vernier collector is fabricated.The image of the ultra-weak emission source is reconstructed.The spatial resolution of the system is about 100μm. | YANG Hao ZHAO BaoSheng YAN QiuRong LIU YongAn HU HuiJun | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，11： | 2 |
| 13 | Shared Gene Regulation during Human Somatic Cell Reprogramming显示文摘人的导致的 pluripotent 茎(iPS ) 细胞有能力区分进所有体的细胞并且维持无限的自强。因此,他们为许多疾病在基本研究和临床的治疗有大潜力。识别人的体的房间 reprogramming 的潜在地通用的机制,我们在经历 reprogramming 的房间的三种类型学习了基因表示变化。通常在 iPS 房间的正式就职期间调整的 570 基因的集合包括已知的胚胎的茎(ES ) 房间标记和 pluripotency 相关基因。我们也识别了可能与体的房间 reprogramming 有关的新奇基因和生物范畴。例如,一些下面调整的基因被预言 pluripotency microRNA 簇 miR302/367 的目标,和从这些通常认为的目标基因的蛋白质根据我们的网络分析与干细胞 pluripotency 因素 POU5F1 交往。我们的结果识别了候选人基因集合在在体的房间 reprogramming 期间操作的机制上指导研究。 | Xiang Wang Xuesong Chen Huijun Zhang Wenyi Qin Yan Xue Fanyi Zeng | 2012 | Journal of Genetics and Genomics2012，39，12： | 2 |
| 14 | A simple and efficient criterion for ready screening of potential topological insulators显示文摘Topological materials are a new and rapidly expanding class of quantum matter. To date, identification of the topological nature of a given compound material demands specific determination of the appropriate topological invariant through detailed electronic structure calculations. Here we present an efficient criterion that allows ready screening of potential topological materials, using topological insulators as prototypical examples. The criterion is inherently tied to the band inversion induced by spin-orbit coupling,and is uniquely defined by a minimal number of two elemental physical properties of the constituent elements: the atomic number and Pauling electronegativity. The validity and predictive power of the criterion is demonstrated by rationalizing many known topological insulators and potential candidates in the tetradymite and half-Heusler families, and the underlying design principle is naturally also extendable to predictive discoveries of other classes of topological materials. | Guohua Cao Huijun Liu Xing-Qiu Chen Yan Sun Jinghua Liang Rui Yu Zhenyu Zhang | 2017 | Science Bulletin2017，62，24： | 1 |
| 15 | Positive association of the human GABA-A-receptor beta 2 subunit gene haplotype with schizophrenia in the Chinese Han population显示文摘 | Jixia Liu Yongyong Shi Wei Tang Tingwei Guo Dawei Li Yifeng Yang Xinzhi Zhao Hongsheng Wang Xingwang Li Guoyin Feng Niufan Gu Shaomin Zhu Huijun Liu Yangling Guo Jianguo Shi Hong Sang Lijuan Yan Lin He | 2005 | Biochemical and Biophysical Research Communications2005，，3： | 1 |
| 16 | Research on the structure configuration synthesis and design criteria of five-axis machining centers 显示文摘 | JianhuiLiu Huijun Zou Hongsen Yan | 2006 | The International Journal of Advanced Manufacture Technology2006，，： | 1 |
| 17 | Usable values for Chinese standard reference samples of stream sediments, soils and rocks: GSDg-12, GSS1-8 and GSP,1-6显示文摘 | Xie Xuejin Yan Mingcai Li Lianzhong Shen Huijun | 1985 | Geostandards Newsletter1985，9，2： | 1 |
| 18 | Electrochemistry and voltammetric determination of tannic acid on a single-wall carbon nanotube-coated glassy carbon electrode显示文摘 | Huijun Wan Qiaoli Zou Rui Yan Faqiong Zhao Baizhao Zeng | 2007 | Microchimica Acta (-)2007，，1： | 1 |
| 19 | Usable values for Chinese standard reference samples of stream sediments, soils, and rocks: GSD 9-12, GSS 1-8 and GSR 1-6显示文摘 | Xie Xuejing Yan Mingcai Li Lianzhong Shen Huijun | 1985 | Geostandard Newslett1985，9，2： | 1 |
| 20 | Geochemical standard reference samples GSD 9-12, GSS 1-8 and GSR 1-6显示文摘 | Xie Xuejing Yan Mingcai Wang Chunshu Li Lianzhong Shen Huijun | 1989 | Geostandard Newslett1989，13，1： | 1 |
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